Protein: AKA12
A-kinase anchor protein 12 (AKAP-12) (A-kinase anchor protein 250 kDa) (AKAP 250) (Gravin) (Myasthenia gravis autoantigen)

Gene: AKA12, AKAP12
Organism: Homo sapiens
Interactions: 134
UniProt ID: Q02952

Gene Ontology (top 5):
GO:0005516 - calmodulin binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

533819

KAP2
cAMP-dependent protein kinase type II-alpha regulatory subunit

3

2

Small-scale

0.847

High

498255

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

2

1

High-throughput

0.737

High

973761

FHL1
Four and a half LIM domains protein 1

3

13

High-throughput

0.674

High

200383

HS12A
Heat shock 70 kDa protein 12A

3

1

High-throughput

0.671

High

566362

KPCA
Protein kinase C alpha type

3

4

Small-scale

0.633

High

338306

EGFR
Epidermal growth factor receptor

2

13

Small-scale

0.624

High

717009

CTNB1
Catenin beta-1

2

8

High-throughput

0.611

High

973775

EID3
EP300-interacting inhibitor of differentiation 3

2

0

High-throughput

0.585

High

506976

LAMP1
Lysosome-associated membrane glycoprotein 1

2

2

High-throughput

0.584

High

547014

EZRI
Ezrin

2

7

High-throughput

0.584

High

914019

RB11A
Ras-related protein Rab-11A

2

2

High-throughput

0.584

High

383753

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

13

High-throughput

0.576

High

166695

CE290
Centrosomal protein of 290 kDa

2

13

High-throughput

0.571

High

182136

PDPK1
3-phosphoinositide-dependent protein kinase 1

2

2

High-throughput

0.571

High

235076

DOK2
Docking protein 2

2

1

High-throughput

0.571

High

272542

OFD1
Centriole and centriolar satellite protein OFD1

2

10

High-throughput

0.571

High

408605

KPCB
Protein kinase C beta type

2

4

High-throughput

0.571

High

442810

HCK
Tyrosine-protein kinase HCK

2

10

High-throughput

0.571

High

522923

SRC
Proto-oncogene tyrosine-protein kinase Src

2

10

High-throughput

0.571

High

596393

RASA1
Ras GTPase-activating protein 1

2

12

High-throughput

0.571

High

657828

ELK4
ETS domain-containing protein Elk-4

2

11

High-throughput

0.571

High

666074

SHC1
SHC-transforming protein 1

2

14

High-throughput

0.571

High

805396

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

2

15

High-throughput

0.571

High

848539

CAV2
Caveolin-2

2

3

High-throughput

0.571

High

876973

CASP9
Caspase-9

2

1

High-throughput

0.571

High

924490

GRB2
Growth factor receptor-bound protein 2

2

16

High-throughput

0.571

High

969071

KPCE
Protein kinase C epsilon type

2

4

High-throughput

0.571

High

972179

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

2

15

High-throughput

0.571

High

973759

PAK1
Serine/threonine-protein kinase PAK 1

2

6

High-throughput

0.571

High

973763

KPCD1
Serine/threonine-protein kinase D1

2

7

High-throughput

0.571

High

973774

ABI1
Abl interactor 1

2

3

High-throughput

0.571

High

973778

SH2D3
SH2 domain-containing protein 3C

2

18

High-throughput

0.571

High

973784

SH3K1
SH3 domain-containing kinase-binding protein 1

2

10

High-throughput

0.571

High

973788

SCLT1
Sodium channel and clathrin linker 1

2

13

High-throughput

0.571

High

973790

SH3G3
Endophilin-A3

2

9

High-throughput

0.571

High

429021

ADRB2
Beta-2 adrenergic receptor

1

4

Small-scale

0.561

High

861706

PLK1
Serine/threonine-protein kinase PLK1

1

6

Small-scale

0.561

High

973787

HS12B
Heat shock 70 kDa protein 12B

2

1

High-throughput

0.558

High

217795

ORC4
Origin recognition complex subunit 4

1

1

High-throughput

0.536

High

257768

SIN3B
Paired amphipathic helix protein Sin3b

1

2

High-throughput

0.536

High

334184

LDHA
L-lactate dehydrogenase A chain

1

3

High-throughput

0.536

High

381940

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

2

High-throughput

0.536

High

529001

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.536

High

568631

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

2

High-throughput

0.536

High

895047

RAB2A
Ras-related protein Rab-2A

1

3

High-throughput

0.536

High

973806

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

2

High-throughput

0.536

High

507613

ACADM
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

973805

SAMH1
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

1

0

High-throughput

0.513

High

414875

CDK1
Cyclin-dependent kinase 1

1

5

Small-scale

0.501

High

890618

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

3

Small-scale

0.501

High

973755

PDE4D
3',5'-cyclic-AMP phosphodiesterase 4D

1

0

Small-scale

0.493

High

973757

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

3

High-throughput

0.489

High

973786

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

1

10

High-throughput

0.489

High

120399

RHOD
Rho-related GTP-binding protein RhoD

1

18

High-throughput

0.479

High

155177

KIF3C
Kinesin-like protein KIF3C

1

3

High-throughput

0.479

High

166369

KIF3B
Kinesin-like protein KIF3B

1

3

High-throughput

0.479

High

178493

STX7
Syntaxin-7

1

1

High-throughput

0.479

High

205291

TGON2
Trans-Golgi network integral membrane protein 2

1

14

High-throughput

0.479

High

279522

FLOT1
Flotillin-1

1

2

High-throughput

0.479

High

322504

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

19

High-throughput

0.479

High

325139

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

1

High-throughput

0.479

High

348627

RASN
GTPase NRas

1

9

High-throughput

0.479

High

350094

RASK
GTPase KRas

1

9

High-throughput

0.479

High

386567

P53
Cellular tumor antigen p53

1

5

High-throughput

0.479

High

418191

NPM
Nucleophosmin

1

4

High-throughput

0.479

High

433709

LYN
Tyrosine-protein kinase Lyn

1

10

High-throughput

0.479

High

499699

CH60
60 kDa heat shock protein, mitochondrial

1

4

High-throughput

0.479

High

503933

HSP7C
Heat shock cognate 71 kDa protein

1

9

High-throughput

0.479

High

527407

LAMP2
Lysosome-associated membrane glycoprotein 2

1

2

High-throughput

0.479

High

531125

EF2
Elongation factor 2

1

4

High-throughput

0.479

High

532506

TCTP
Translationally-controlled tumor protein

1

2

High-throughput

0.479

High

545332

RAC2
Ras-related C3 botulinum toxin substrate 2

1

12

High-throughput

0.479

High

564487

RHOQ
Rho-related GTP-binding protein RhoQ

1

17

High-throughput

0.479

High

592213

RAB5A
Ras-related protein Rab-5A

1

3

High-throughput

0.479

High

674400

UFO
Tyrosine-protein kinase receptor UFO

1

7

Small-scale

0.479

High

749398

BRCA1
Breast cancer type 1 susceptibility protein

1

11

High-throughput

0.479

High

793281

MUC18
Cell surface glycoprotein MUC18

1

3

High-throughput

0.479

High

838628

GDIB
Rab GDP dissociation inhibitor beta

1

3

High-throughput

0.479

High

844884

RAB7A
Ras-related protein Rab-7a

1

3

High-throughput

0.479

High

881502

ARL4C
ADP-ribosylation factor-like protein 4C

1

8

High-throughput

0.479

High

892327

RAC3
Ras-related C3 botulinum toxin substrate 3

1

13

High-throughput

0.479

High

893919

CDC42
Cell division control protein 42 homolog

1

14

High-throughput

0.479

High

900397

RHOA
Transforming protein RhoA

1

16

High-throughput

0.479

High

901132

RND3
Rho-related GTP-binding protein RhoE

1

17

High-throughput

0.479

High

912864

ARF6
ADP-ribosylation factor 6

1

1

High-throughput

0.479

High

915621

RHOB
Rho-related GTP-binding protein RhoB

1

16

High-throughput

0.479

High

925213

RAC1
Ras-related C3 botulinum toxin substrate 1

1

14

High-throughput

0.479

High

950936

RHOG
Rho-related GTP-binding protein RhoG

1

13

High-throughput

0.479

High

973754

CAV1
Caveolin-1

1

3

High-throughput

0.479

High

973756

FOXO1
Forkhead box protein O1

1

6

High-throughput

0.479

High

973758

STK4
Serine/threonine-protein kinase 4

1

9

High-throughput

0.479

High

973762

TRI14
Tripartite motif-containing protein 14

1

1

High-throughput

0.479

High

973764

RAB35
Ras-related protein Rab-35

1

3

High-throughput

0.479

High

973765

RHOH
Rho-related GTP-binding protein RhoH

1

16

High-throughput

0.479

High

973768

AR13B
ADP-ribosylation factor-like protein 13B

1

3

High-throughput

0.479

High

973769

RHDF2
Inactive rhomboid protein 2

1

2

High-throughput

0.479

High

973770

TRI67
Tripartite motif-containing protein 67

1

17

High-throughput

0.479

High

973771

RHOU
Rho-related GTP-binding protein RhoU

1

17

High-throughput

0.479

High

973772

ZN598
E3 ubiquitin-protein ligase ZNF598

1

10

High-throughput

0.479

High

973773

NAA40
N-alpha-acetyltransferase 40

1

4

High-throughput

0.479

High

973776

ARL14
ADP-ribosylation factor-like protein 14

1

2

High-throughput

0.479

High

973779

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

4

High-throughput

0.479

High

973780

DYRK2
Dual specificity tyrosine-phosphorylation-regulated kinase 2

1

20

High-throughput

0.479

High

973781

NECT2
Nectin-2

1

3

High-throughput

0.479

High

973782

FBX32
F-box only protein 32

1

1

High-throughput

0.479

High

973789

FMNL2
Formin-like protein 2

1

1

High-throughput

0.479

High

973791

CP250
Centrosome-associated protein CEP250

1

10

High-throughput

0.479

High

973793

TOLIP
Toll-interacting protein

1

1

High-throughput

0.479

High

973794

SAV1
Protein salvador homolog 1

1

8

High-throughput

0.479

High

973795

Q9H4D1
Protein kinase

1

5

High-throughput

0.479

High

973796

RHOJ
Rho-related GTP-binding protein RhoJ

1

16

High-throughput

0.479

High

973797

PKHA4
Pleckstrin homology domain-containing family A member 4

1

9

High-throughput

0.479

High

973799

RHOF
Rho-related GTP-binding protein RhoF

1

17

High-throughput

0.479

High

973802

HDAC6
Histone deacetylase 6

1

10

Small-scale

0.479

High

973803

PRP19
Pre-mRNA-processing factor 19

1

15

Small-scale

0.479

High

973804

LAMP3
Lysosome-associated membrane glycoprotein 3

1

2

High-throughput

0.479

High

146028

CLD4
Claudin-4

1

0

Small-scale

0.458

High

212802

STX6
Syntaxin-6

1

0

High-throughput

0.458

High

544959

AMPN
Aminopeptidase N

1

0

High-throughput

0.458

High

973767

OCLN
Occludin

1

0

High-throughput

0.458

High

973785

GCP3
Gamma-tubulin complex component 3

1

0

High-throughput

0.458

High

883490

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

7

High-throughput

0.445

High

973760

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

16

High-throughput

0.445

High

100691

APRIO
Alternative prion protein

1

3

High-throughput

0.437

High

276820

SCO1
Protein SCO1 homolog, mitochondrial

1

1

High-throughput

0.437

High

973800

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

4

High-throughput

0.437

High

973801

ARL15
ADP-ribosylation factor-like protein 15

1

3

High-throughput

0.437

High

973766

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

0

High-throughput

0.279

Low

305421

ZFPL1
Zinc finger protein-like 1

1

0

High-throughput

0.249

Low

973783

CK052
Uncharacterized protein C11orf52

1

0

High-throughput

0.249

Low

973792

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

Small-scale

0.249

Low

973798

SFXN1
Sideroflexin-1

1

0

High-throughput

0.249

Low

224677

SSX4
Protein SSX4

1

0

High-throughput

0.232

Low

973777

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024