Protein: MEF2C
Myocyte-specific enhancer factor 2C (Myocyte enhancer factor 2C)

Gene: MEF2C
Organism: Homo sapiens
Interactions: 46
UniProt ID: Q06413

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000165 - MAPK cascade
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

968772

MEF2A
Myocyte-specific enhancer factor 2A

2

19

High-throughput

0.811

High

968809

MEF2B
Myocyte-specific enhancer factor 2B

2

16

High-throughput

0.811

High

880693

HDAC4
Histone deacetylase 4

11

20

Small-scale

0.756

High

987212

MEF2C
Myocyte-specific enhancer factor 2C

1

18

Small-scale

0.647

High

987223

HDAC7
Histone deacetylase 7

3

20

Small-scale

0.641

High

987234

HDAC5
Histone deacetylase 5

3

20

Small-scale

0.636

High

987215

MK07
Mitogen-activated protein kinase 7

2

16

Small-scale

0.633

High

987233

HDAC9
Histone deacetylase 9

2

20

High-throughput

0.632

High

987213

EP300
Histone acetyltransferase p300

2

6

Small-scale

0.595

High

545962

MYOD1
Myoblast determination protein 1

2

7

Small-scale

0.594

High

129123

IFRD1
Interferon-related developmental regulator 1

1

1

Small-scale

0.561

High

658488

TEAD1
Transcriptional enhancer factor TEF-1

1

3

Small-scale

0.561

High

727955

SOX18
Transcription factor SOX-18

1

6

Small-scale

0.561

High

987231

MYLK2
Myosin light chain kinase 2, skeletal/cardiac muscle

1

3

Small-scale

0.561

High

435063

SP1
Transcription factor Sp1

1

8

Small-scale

0.552

High

926958

1433Z
14-3-3 protein zeta/delta

1

4

High-throughput

0.541

High

963300

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

1

High-throughput

0.541

High

987221

MK14
Mitogen-activated protein kinase 14

1

14

High-throughput

0.541

High

987225

CSN5
COP9 signalosome complex subunit 5

1

1

High-throughput

0.541

High

987227

EPAS1
Endothelial PAS domain-containing protein 1

1

1

High-throughput

0.541

High

987228

PG12A
Group XIIA secretory phospholipase A2

1

0

High-throughput

0.518

High

134882

IMA3
Importin subunit alpha-3

1

1

High-throughput

0.501

High

546079

MYOG
Myogenin

1

8

Small-scale

0.501

High

930163

UBC9
SUMO-conjugating enzyme UBC9

1

2

Small-scale

0.501

High

987218

NCOA2
Nuclear receptor coactivator 2

1

5

Small-scale

0.501

High

987220

SMAD2
Mothers against decapentaplegic homolog 2

1

3

Small-scale

0.501

High

987232

HIPK2
Homeodomain-interacting protein kinase 2

1

7

Small-scale

0.500

High

840628

ASCL1
Achaete-scute homolog 1

1

4

Small-scale

0.481

High

987217

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.479

High

346604

MYC
Myc proto-oncogene protein

1

1

Small-scale

0.479

High

817960

SOX2
Transcription factor SOX-2

1

6

High-throughput

0.479

High

987214

TFCP2
Alpha-globin transcription factor CP2

1

2

High-throughput

0.479

High

987216

SKP2
S-phase kinase-associated protein 2

1

1

Small-scale

0.479

High

987219

ELF2
ETS-related transcription factor Elf-2

1

6

High-throughput

0.479

High

987224

TWST2
Twist-related protein 2

1

8

Small-scale

0.479

High

262437

TULP3
Tubby-related protein 3

1

0

High-throughput

0.458

High

983103

UBE3A
Ubiquitin-protein ligase E3A

1

0

Small-scale

0.458

High

987230

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.458

High

987222

ZBT44
Zinc finger and BTB domain-containing protein 44

1

1

High-throughput

0.457

High

987226

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

1

4

High-throughput

0.457

High

987229

ZN350
Zinc finger protein 350

1

1

High-throughput

0.457

High

401884

JUN
Transcription factor Jun

1

5

High-throughput

0.445

High

307025

RTN3
Reticulon-3

1

0

High-throughput

0.438

High

829167

SYAC
Alanine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.438

High

100701

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024