Protein: ULA1
NEDD8-activating enzyme E1 regulatory subunit (Amyloid beta precursor protein-binding protein 1, 59 kDa) (APP-BP1) (Amyloid protein-binding protein 1) (Proto-oncogene protein 1)

Gene: ULA1, NAE1
Organism: Homo sapiens
Interactions: 54
UniProt ID: Q13564

Gene Ontology (top 5):
GO:0004839 - ubiquitin activating enzyme activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1039432

UBA3
NEDD8-activating enzyme E1 catalytic subunit

11

13

Small-scale

0.974

High

896070

UBC12
NEDD8-conjugating enzyme Ubc12

9

20

Small-scale

0.973

High

1039423

NEDD8
NEDD8

7

4

Small-scale

0.947

High

227383

PRKN
E3 ubiquitin-protein ligase parkin

2

7

High-throughput

0.754

High

1039444

UBQL4
Ubiquilin-4

1

7

High-throughput

0.698

High

1039434

UBE2F
NEDD8-conjugating enzyme UBE2F

1

20

Small-scale

0.647

High

394679

A4
Amyloid-beta precursor protein

2

5

Small-scale

0.634

High

908500

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

20

High-throughput

0.618

High

1039431

ZBT44
Zinc finger and BTB domain-containing protein 44

2

1

High-throughput

0.611

High

1039422

TRIPC
E3 ubiquitin-protein ligase TRIP12

1

7

Small-scale

0.561

High

1016057

SRBP2
Sterol regulatory element-binding protein 2

1

1

High-throughput

0.541

High

782899

GARS
Glycine--tRNA ligase

1

0

Small-scale

0.537

High

1039430

SERB1
SERPINE1 mRNA-binding protein 1

1

2

High-throughput

0.536

High

1039443

LRTM1
Leucine-rich repeat and transmembrane domain-containing protein 1

1

1

High-throughput

0.536

High

1039447

NTNG1
Netrin-G1

1

1

High-throughput

0.536

High

1039449

SAR1B
Small COPII coat GTPase SAR1B

1

2

High-throughput

0.536

High

1039436

UIMC1
BRCA1-A complex subunit RAP80

1

1

High-throughput

0.515

High

842116

R144A
E3 ubiquitin-protein ligase RNF144A

1

0

High-throughput

0.513

High

1000239

RIPP1
Protein ripply1

1

0

High-throughput

0.513

High

1039427

ZN684
Zinc finger protein 684

1

0

High-throughput

0.513

High

1039448

WIF1
Wnt inhibitory factor 1

1

0

High-throughput

0.513

High

174864

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

4

High-throughput

0.501

High

1039437

TGS1
Trimethylguanosine synthase

1

0

High-throughput

0.493

High

1039424

ANR39
Ankyrin repeat domain-containing protein 39

1

4

High-throughput

0.489

High

205369

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.479

High

244401

BRD4
Bromodomain-containing protein 4

1

3

High-throughput

0.479

High

294808

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.479

High

383788

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

1

Small-scale

0.479

High

384797

NTRK1
High affinity nerve growth factor receptor

1

4

High-throughput

0.479

High

401959

JUN
Transcription factor Jun

1

7

High-throughput

0.479

High

552666

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.479

High

569698

CEBPB
CCAAT/enhancer-binding protein beta

1

5

High-throughput

0.479

High

651141

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.479

High

1026400

RFA4
Replication protein A 30 kDa subunit

1

4

High-throughput

0.479

High

1036550

SQSTM
Sequestosome-1

1

1

High-throughput

0.479

High

1039421

ASPP2
Apoptosis-stimulating of p53 protein 2

1

5

Small-scale

0.479

High

1039428

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.479

High

1039433

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

1039438

DNJC7
DnaJ homolog subfamily C member 7

1

5

High-throughput

0.479

High

1039440

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

2

Small-scale

0.479

High

1039441

PKHA4
Pleckstrin homology domain-containing family A member 4

1

5

High-throughput

0.479

High

1039442

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.479

High

1039445

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

1039446

HERC5
E3 ISG15--protein ligase HERC5

1

9

Small-scale

0.479

High

1039425

DCAF6
DDB1- and CUL4-associated factor 6

1

0

High-throughput

0.458

High

1039435

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

378043

PRIO
Major prion protein

1

2

High-throughput

0.445

High

1039426

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

6

High-throughput

0.445

High

100739

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

720402

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.437

High

831301

CEBPA
CCAAT/enhancer-binding protein alpha

1

5

High-throughput

0.408

High

1039439

ALG8
Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase

1

0

High-throughput

0.282

High

1039429

T183A
Transmembrane protein 183A

1

0

High-throughput

0.279

Low

429525

HEXB
Beta-hexosaminidase subunit beta

1

0

High-throughput

0.268

Low


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Last updated: 15 Jul 2024