Protein: FHL1
Four and a half LIM domains protein 1 (FHL-1) (Skeletal muscle LIM-protein 1) (SLIM) (SLIM-1)

Gene: FHL1
Organism: Homo sapiens
Interactions: 126
UniProt ID: Q13642

Gene Ontology (top 5):
GO:0003254 - regulation of membrane depolarization
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

839860

CSRP3
Cysteine and glycine-rich protein 3

1

18

High-throughput

0.698

High

1044547

PDLI3
PDZ and LIM domain protein 3

1

19

High-throughput

0.698

High

1044566

AJUBA
LIM domain-containing protein ajuba

1

18

High-throughput

0.691

High

1044580

PDLI7
PDZ and LIM domain protein 7

1

18

High-throughput

0.691

High

986904

SUH
Recombining binding protein suppressor of hairless

4

1

Small-scale

0.686

High

973761

AKA12
A-kinase anchor protein 12

3

13

High-throughput

0.674

High

1044537

HES1
Transcription factor HES-1

1

1

High-throughput

0.656

High

1044536

FHL2
Four and a half LIM domains protein 2

1

18

Small-scale

0.647

High

962502

MYPC1
Myosin-binding protein C, slow-type

2

12

Small-scale

0.646

High

673578

MPIP3
M-phase inducer phosphatase 3

2

5

Small-scale

0.631

High

379379

MYCN
N-myc proto-oncogene protein

1

14

High-throughput

0.618

High

1044563

FERM2
Fermitin family homolog 2

1

6

Small-scale

0.618

High

1044559

TITIN
Titin

2

11

Small-scale

0.613

High

394686

A4
Amyloid-beta precursor protein

2

13

High-throughput

0.608

High

369562

ESR1
Estrogen receptor

2

18

Small-scale

0.601

High

378045

PRIO
Major prion protein

2

1

Small-scale

0.585

High

435087

SP1
Transcription factor Sp1

2

20

Small-scale

0.584

High

673401

MPIP1
M-phase inducer phosphatase 1

2

5

Small-scale

0.584

High

998683

EP300
Histone acetyltransferase p300

2

10

Small-scale

0.584

High

1044577

PKHG2
Pleckstrin homology domain-containing family G member 2

2

18

Small-scale

0.584

High

1035425

SMAD4
Mothers against decapentaplegic homolog 4

1

17

Small-scale

0.578

High

1044540

SMAD2
Mothers against decapentaplegic homolog 2

1

17

Small-scale

0.578

High

331282

CHK2
Serine/threonine-protein kinase Chk2

1

5

Small-scale

0.573

High

909540

1433E
14-3-3 protein epsilon

1

4

Small-scale

0.573

High

987968

RING1
E3 ubiquitin-protein ligase RING1

1

9

Small-scale

0.573

High

1044548

ZEP3
Transcription factor HIVEP3

1

11

Small-scale

0.573

High

496985

TAU
Microtubule-associated protein tau

2

12

High-throughput

0.571

High

1044568

SRPK1
SRSF protein kinase 1

1

6

High-throughput

0.569

High

819628

NRIP1
Nuclear receptor-interacting protein 1

1

0

Small-scale

0.569

High

822259

KC1D
Casein kinase I isoform delta

1

2

Small-scale

0.561

High

950172

SMAD3
Mothers against decapentaplegic homolog 3

1

17

Small-scale

0.561

High

1044545

HIF1A
Hypoxia-inducible factor 1-alpha

1

5

Small-scale

0.561

High

1044586

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

1

Small-scale

0.561

High

608276

KCNA5
Potassium voltage-gated channel subfamily A member 5

2

0

Small-scale

0.559

High

620151

PAX7
Paired box protein Pax-7

1

4

High-throughput

0.541

High

1044544

NFIL3
Nuclear factor interleukin-3-regulated protein

1

5

High-throughput

0.541

High

1044567

CLMN
Calmin

1

11

High-throughput

0.541

High

1044571

DOCK9
Dedicator of cytokinesis protein 9

1

4

High-throughput

0.541

High

1044581

ZBT40
Zinc finger and BTB domain-containing protein 40

1

19

High-throughput

0.541

High

1044584

MACF1
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5

1

8

High-throughput

0.541

High

325723

LATS1
Serine/threonine-protein kinase LATS1

1

4

High-throughput

0.536

High

529085

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.536

High

1044542

MK14
Mitogen-activated protein kinase 14

1

8

High-throughput

0.536

High

1044554

ZN444
Zinc finger protein 444

1

20

High-throughput

0.536

High

1044556

ZN784
Zinc finger protein 784

1

18

High-throughput

0.536

High

1044558

NEK7
Serine/threonine-protein kinase Nek7

1

4

High-throughput

0.536

High

1044573

MYLK2
Myosin light chain kinase 2, skeletal/cardiac muscle

1

8

High-throughput

0.536

High

1044575

KDM4C
Lysine-specific demethylase 4C

1

3

High-throughput

0.536

High

1044579

ZNF71
Endothelial zinc finger protein induced by tumor necrosis factor alpha

1

19

High-throughput

0.536

High

417277

ENOA
Alpha-enolase

1

0

High-throughput

0.518

High

873698

SLUR1
Secreted Ly-6/uPAR-related protein 1

1

0

High-throughput

0.513

High

1044546

UPP1
Uridine phosphorylase 1

1

0

High-throughput

0.513

High

263434

DEAF1
Deformed epidermal autoregulatory factor 1 homolog

1

4

High-throughput

0.508

High

268077

EED
Polycomb protein EED

1

5

High-throughput

0.508

High

1044543

DREB
Drebrin

1

8

High-throughput

0.508

High

1044549

MYOME
Myomegalin

1

9

High-throughput

0.508

High

915186

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

6

Small-scale

0.506

High

515587

SRF
Serum response factor

1

1

Small-scale

0.501

High

234708

ZIC3
Zinc finger protein ZIC 3

1

18

High-throughput

0.500

High

623622

IBP5
Insulin-like growth factor-binding protein 5

1

1

High-throughput

0.494

High

1044541

LAMA4
Laminin subunit alpha-4

1

1

High-throughput

0.494

High

1044574

TXNIP
Thioredoxin-interacting protein

1

0

High-throughput

0.486

High

119363

LEG9
Galectin-9

1

3

High-throughput

0.479

High

129755

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

14

High-throughput

0.479

High

227397

PRKN
E3 ubiquitin-protein ligase parkin

1

17

High-throughput

0.479

High

322593

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

11

High-throughput

0.479

High

338399

EGFR
Epidermal growth factor receptor

1

18

High-throughput

0.479

High

354441

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

3

High-throughput

0.479

High

359925

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

14

High-throughput

0.479

High

475733

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

8

High-throughput

0.479

High

504046

HSP7C
Heat shock cognate 71 kDa protein

1

7

High-throughput

0.479

High

505630

EPB41
Protein 4.1

1

8

High-throughput

0.479

High

522967

SRC
Proto-oncogene tyrosine-protein kinase Src

1

20

Small-scale

0.479

High

523738

XRCC6
X-ray repair cross-complementing protein 6

1

1

High-throughput

0.479

High

552679

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

584958

RO52
E3 ubiquitin-protein ligase TRIM21

1

14

High-throughput

0.479

High

617540

CRCM
Colorectal mutant cancer protein

1

8

High-throughput

0.479

High

641766

U2AF2
Splicing factor U2AF 65 kDa subunit

1

7

High-throughput

0.479

High

658935

MK01
Mitogen-activated protein kinase 1

1

7

Small-scale

0.479

High

673478

MPIP2
M-phase inducer phosphatase 2

1

5

Small-scale

0.479

High

681836

AKT1
RAC-alpha serine/threonine-protein kinase

1

5

Small-scale

0.479

High

684023

1433S
14-3-3 protein sigma

1

20

Small-scale

0.479

High

708636

MCM5
DNA replication licensing factor MCM5

1

2

High-throughput

0.479

High

742286

SYUA
Alpha-synuclein

1

1

High-throughput

0.479

High

908504

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

4

High-throughput

0.479

High

927022

1433Z
14-3-3 protein zeta/delta

1

20

Small-scale

0.479

High

967161

EWS
RNA-binding protein EWS

1

5

High-throughput

0.479

High

1025014

REST
RE1-silencing transcription factor

1

20

High-throughput

0.479

High

1026403

RFA4
Replication protein A 30 kDa subunit

1

1

High-throughput

0.479

High

1035705

BIRC3
Baculoviral IAP repeat-containing protein 3

1

2

High-throughput

0.479

High

1041524

CUL3
Cullin-3

1

20

High-throughput

0.479

High

1044535

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

2

High-throughput

0.479

High

1044538

MDC1
Mediator of DNA damage checkpoint protein 1

1

15

High-throughput

0.479

High

1044539

SF3A1
Splicing factor 3A subunit 1

1

11

High-throughput

0.479

High

1044551

RICTR
Rapamycin-insensitive companion of mTOR

1

1

High-throughput

0.479

High

1044552

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.479

High

1044553

GOLI
E3 ubiquitin-protein ligase RNF130

1

3

High-throughput

0.479

High

1044555

RN149
E3 ubiquitin-protein ligase RNF149

1

2

High-throughput

0.479

High

1044557

BICD2
Protein bicaudal D homolog 2

1

10

High-throughput

0.479

High

1044560

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

High-throughput

0.479

High

1044561

CBP
CREB-binding protein

1

11

Small-scale

0.479

High

1044564

BICD1
Protein bicaudal D homolog 1

1

9

High-throughput

0.479

High

1044565

DDRGK
DDRGK domain-containing protein 1

1

2

High-throughput

0.479

High

1044576

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.479

High

1044578

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

7

High-throughput

0.479

High

1044583

BCLF1
Bcl-2-associated transcription factor 1

1

7

Small-scale

0.479

High

154185

CHK1
Serine/threonine-protein kinase Chk1

1

0

Small-scale

0.458

High

651156

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

914059

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.458

High

920961

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

0

Small-scale

0.458

High

961101

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

1018788

SF3A3
Splicing factor 3A subunit 3

1

0

High-throughput

0.458

High

1030223

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.458

High

1044570

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

1044572

IMUP
Immortalization up-regulated protein

1

0

Small-scale

0.458

High

1044585

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

0

High-throughput

0.458

High

100747

APRIO
Alternative prion protein

1

3

Small-scale

0.457

High

131246

BIN1
Myc box-dependent-interacting protein 1

1

9

High-throughput

0.457

High

563303

ZNF16
Zinc finger protein 16

1

10

Small-scale

0.457

High

401967

JUN
Transcription factor Jun

1

13

High-throughput

0.445

High

1044550

OTUD1
OTU domain-containing protein 1

1

2

High-throughput

0.437

High

1044569

ERP44
Endoplasmic reticulum resident protein 44

1

1

High-throughput

0.437

High

1044582

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

2

High-throughput

0.437

High

893274

SNP25
Synaptosomal-associated protein 25

1

0

Small-scale

0.426

High

1044562

TANK
TRAF family member-associated NF-kappa-B activator

1

0

High-throughput

0.426

High

720414

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024