Protein: DOCK4
Dedicator of cytokinesis protein 4

Gene: DOCK4
Organism: Homo sapiens
Interactions: 67
UniProt ID: Q8N1I0

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005096 - GTPase activator activity
GO:0005730 - nucleolus
GO:0005737 - cytoplasm
GO:0005794 - Golgi apparatus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

924698

GRB2
Growth factor receptor-bound protein 2

6

20

High-throughput

0.946

High

1230987

ELMO1
Engulfment and cell motility protein 1

4

20

Small-scale

0.897

High

1230992

ELMO2
Engulfment and cell motility protein 2

3

20

High-throughput

0.849

High

786389

STAT1
Signal transducer and activator of transcription 1-alpha/beta

2

1

High-throughput

0.811

High

1230990

ELMO3
Engulfment and cell motility protein 3

2

20

High-throughput

0.811

High

1224218

DOCK3
Dedicator of cytokinesis protein 3

1

12

High-throughput

0.691

High

1230995

ERMAP
Erythroid membrane-associated protein

2

1

High-throughput

0.628

High

925429

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

1078864

ITSN1
Intersectin-1

1

4

High-throughput

0.618

High

827243

ARRB1
Beta-arrestin-1

2

0

High-throughput

0.602

High

338691

EGFR
Epidermal growth factor receptor

2

16

Small-scale

0.584

High

1230988

ARHG1
Rho guanine nucleotide exchange factor 1

2

3

High-throughput

0.584

High

1230996

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

1

3

High-throughput

0.575

High

1109014

RHGBB
Inactive Rho GTPase-activating protein 11B

2

8

High-throughput

0.571

High

484307

VSIG8
V-set and immunoglobulin domain-containing protein 8

2

4

High-throughput

0.552

High

498310

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

2

0

High-throughput

0.547

High

362243

GLPA
Glycophorin-A

1

1

High-throughput

0.536

High

957431

IDD
Integral membrane protein DGCR2/IDD

1

2

High-throughput

0.536

High

499921

CH60
60 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.515

High

541067

HNRPL
Heterogeneous nuclear ribonucleoprotein L

1

1

High-throughput

0.515

High

683533

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.515

High

856417

EFNA4
Ephrin-A4

1

0

High-throughput

0.513

High

1218809

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1230989

MUL1
Mitochondrial ubiquitin ligase activator of NFKB 1

1

0

High-throughput

0.513

High

1230999

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.513

High

152310

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

5

Small-scale

0.501

High

1231005

NPTN
Neuroplastin

1

2

High-throughput

0.489

High

1231004

RN115
E3 ubiquitin-protein ligase RNF115

1

1

Small-scale

0.481

High

815698

TNFL6
Tumor necrosis factor ligand superfamily member 6

1

0

Small-scale

0.480

High

134120

DDX3X
ATP-dependent RNA helicase DDX3X

1

1

High-throughput

0.479

High

385158

NTRK1
High affinity nerve growth factor receptor

1

6

High-throughput

0.479

High

409162

K2C8
Keratin, type II cytoskeletal 8

1

1

High-throughput

0.479

High

430261

PROF1
Profilin-1

1

5

High-throughput

0.479

High

443649

VIME
Vimentin

1

3

High-throughput

0.479

High

714557

GRK5
G protein-coupled receptor kinase 5

1

2

High-throughput

0.479

High

749672

BRCA1
Breast cancer type 1 susceptibility protein

1

1

High-throughput

0.479

High

757681

IF4A3
Eukaryotic initiation factor 4A-III

1

3

High-throughput

0.479

High

823445

PAXI
Paxillin

1

1

High-throughput

0.479

High

850682

KS6A3
Ribosomal protein S6 kinase alpha-3

1

6

High-throughput

0.479

High

893086

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

904844

1433G
14-3-3 protein gamma

1

20

High-throughput

0.479

High

908806

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.479

High

982263

1433F
14-3-3 protein eta

1

20

High-throughput

0.479

High

1071660

KS6A2
Ribosomal protein S6 kinase alpha-2

1

6

High-throughput

0.479

High

1073450

KS6A1
Ribosomal protein S6 kinase alpha-1

1

6

High-throughput

0.479

High

1168576

SYNE3
Nesprin-3

1

4

High-throughput

0.479

High

1169964

RHG36
Rho GTPase-activating protein 36

1

8

High-throughput

0.479

High

1170781

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.479

High

1230986

BICD2
Protein bicaudal D homolog 2

1

5

High-throughput

0.479

High

1230991

BICD1
Protein bicaudal D homolog 1

1

4

High-throughput

0.479

High

1230994

ARHGH
Rho guanine nucleotide exchange factor 17

1

3

High-throughput

0.479

High

1230998

PKHA4
Pleckstrin homology domain-containing family A member 4

1

10

High-throughput

0.479

High

1231002

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

1231003

MARE3
Microtubule-associated protein RP/EB family member 3

1

3

High-throughput

0.479

High

166278

GRRE1
Granule associated Rac and RHOG effector protein 1

1

0

High-throughput

0.458

High

296947

LTN1
E3 ubiquitin-protein ligase listerin

1

0

High-throughput

0.458

High

326710

SNAI1
Zinc finger protein SNAI1

1

0

High-throughput

0.458

High

418452

NPM
Nucleophosmin

1

0

High-throughput

0.458

High

899520

MGN
Protein mago nashi homolog

1

0

High-throughput

0.458

High

1230993

ZDH15
Palmitoyltransferase ZDHHC15

1

0

Small-scale

0.458

High

1231001

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

Small-scale

0.458

High

1124557

ODFP2
Outer dense fiber protein 2

1

3

High-throughput

0.445

High

100941

APRIO
Alternative prion protein

1

3

High-throughput

0.437

High

1159391

FBX42
F-box only protein 42

1

2

High-throughput

0.437

High

1231000

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

1

High-throughput

0.437

High

1160073

RL22L
Ribosomal protein eL22-like

1

0

High-throughput

0.249

Low

1230997

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024