Protein: CWC15
Spliceosome-associated protein CWC15 homolog

Gene: CWC15
Organism: Homo sapiens
Interactions: 89
UniProt ID: Q9P013

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0000974 - Prp19 complex
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1349487

PRP19
Pre-mRNA-processing factor 19

3

2

Small-scale

0.855

High

1264440

CTBL1
Beta-catenin-like protein 1

6

2

Small-scale

0.746

High

1303817

CDC5L
Cell division cycle 5-like protein

4

2

Small-scale

0.691

High

1289460

SIR1
NAD-dependent protein deacetylase sirtuin-1

3

1

High-throughput

0.667

High

1347878

SIR5
NAD-dependent protein deacylase sirtuin-5, mitochondrial

3

1

High-throughput

0.667

High

1039903

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.656

High

1288353

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

2

High-throughput

0.618

High

1105494

LRRK1
Leucine-rich repeat serine/threonine-protein kinase 1

2

1

High-throughput

0.602

High

1346733

DJC17
DnaJ homolog subfamily C member 17

2

0

High-throughput

0.595

High

278555

SPF27
Pre-mRNA-splicing factor SPF27

2

0

Small-scale

0.576

High

209490

PLRG1
Pleiotropic regulator 1

1

1

Small-scale

0.575

High

1146906

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.553

High

440777

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

1

High-throughput

0.536

High

453925

RU2A
U2 small nuclear ribonucleoprotein A'

1

2

High-throughput

0.536

High

757782

IF4A3
Eukaryotic initiation factor 4A-III

1

1

High-throughput

0.536

High

958000

FGD1
FYVE, RhoGEF and PH domain-containing protein 1

2

1

High-throughput

0.521

High

1218350

ARHGJ
Rho guanine nucleotide exchange factor 19

2

1

High-throughput

0.521

High

268886

SF3B1
Splicing factor 3B subunit 1

1

0

High-throughput

0.513

High

327820

SYF2
Pre-mRNA-splicing factor SYF2

1

0

High-throughput

0.513

High

446819

SNRPA
U1 small nuclear ribonucleoprotein A

1

0

High-throughput

0.513

High

448837

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.513

High

508749

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.513

High

539169

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

0

High-throughput

0.513

High

739327

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.513

High

881319

CTBP2
C-terminal-binding protein 2

1

0

High-throughput

0.513

High

911756

RUXE
Small nuclear ribonucleoprotein E

1

0

High-throughput

0.513

High

984544

KPCD
Protein kinase C delta type

1

0

High-throughput

0.513

High

989158

FMR1
Fragile X messenger ribonucleoprotein 1

1

0

High-throughput

0.513

High

1042706

CUL3
Cullin-3

1

0

High-throughput

0.513

High

1054634

RBM39
RNA-binding protein 39

1

0

High-throughput

0.513

High

1074252

SF3A1
Splicing factor 3A subunit 1

1

0

High-throughput

0.513

High

1084650

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

0

High-throughput

0.513

High

1087886

PCKGM
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial

1

0

High-throughput

0.513

High

1260029

CCD12
Coiled-coil domain-containing protein 12

1

0

High-throughput

0.513

High

1308999

USB1
U6 snRNA phosphodiesterase 1

1

0

High-throughput

0.513

High

1334089

ARMT1
Damage-control phosphatase ARMT1

1

0

High-throughput

0.513

High

1349486

ISY1
Pre-mRNA-splicing factor ISY1 homolog

1

0

High-throughput

0.513

High

1349488

PPIE
Peptidyl-prolyl cis-trans isomerase E

1

0

High-throughput

0.513

High

1349489

PPIL1
Peptidyl-prolyl cis-trans isomerase-like 1

1

0

High-throughput

0.513

High

1349490

TSSC4
U5 small nuclear ribonucleoprotein TSSC4

1

0

High-throughput

0.513

High

1294312

SPF45
Splicing factor 45

1

1

High-throughput

0.508

High

1130674

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.501

High

1269791

ESR2
Estrogen receptor beta

1

1

High-throughput

0.484

High

348094

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

377750

GCR
Glucocorticoid receptor

1

1

High-throughput

0.479

High

379963

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

1080414

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

High-throughput

0.479

High

1347089

RBM22
Pre-mRNA-splicing factor RBM22

1

1

High-throughput

0.479

High

295332

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

375000

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

719200

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

824473

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

899570

MGN
Protein mago nashi homolog

1

0

High-throughput

0.458

High

918052

H4
Histone H4

1

0

High-throughput

0.458

High

935314

H31
Histone H3.1

1

0

High-throughput

0.458

High

959729

VIGLN
Vigilin

1

0

High-throughput

0.458

High

961301

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

967482

EWS
RNA-binding protein EWS

1

0

High-throughput

0.458

High

1024430

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

0

High-throughput

0.458

High

1055494

DHX8
ATP-dependent RNA helicase DHX8

1

0

High-throughput

0.458

High

1063654

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.458

High

1073738

SF3A2
Splicing factor 3A subunit 2

1

0

High-throughput

0.458

High

1081427

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

1153953

IFIX
Pyrin and HIN domain-containing protein 1

1

0

High-throughput

0.458

High

1200708

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1201728

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.458

High

1221791

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1243971

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

1251054

SNIP1
Smad nuclear-interacting protein 1

1

0

High-throughput

0.458

High

1313201

DDX23
Probable ATP-dependent RNA helicase DDX23

1

0

High-throughput

0.458

High

1343723

ANLN
Anillin

1

0

High-throughput

0.458

High

1348356

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

1349485

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

324894

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

1

High-throughput

0.437

High

402558

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

504879

HSP7C
Heat shock cognate 71 kDa protein

1

0

Small-scale

0.426

High

1222613

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.426

High

207208

SGCE
Epsilon-sarcoglycan

1

0

High-throughput

0.282

High

826492

FNTB
Protein farnesyltransferase subunit beta

1

0

High-throughput

0.279

Low

1316139

ANGL4
Angiopoietin-related protein 4

1

0

High-throughput

0.279

Low

101242

APRIO
Alternative prion protein

1

0

Small-scale

0.261

Low

378194

PRIO
Major prion protein

1

0

Small-scale

0.261

Low

395943

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.261

Low

571230

EGLN
Endoglin

1

0

High-throughput

0.261

Low

149374

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

892639

RAC3
Ras-related C3 botulinum toxin substrate 3

1

0

High-throughput

0.249

Low

932419

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.249

Low

992522

SOS2
Son of sevenless homolog 2

1

0

High-throughput

0.249

Low

240223

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024