Protein: NGAP
Ras GTPase-activating protein nGAP (RAS protein activator-like 2)

Gene: NGAP, RASAL2
Organism: Homo sapiens
Interactions: 150
UniProt ID: Q9UJF2

Gene Ontology (top 5):
GO:0002021 - response to dietary excess
GO:0005096 - GTPase activator activity
GO:0005829 - cytosol
GO:0007165 - signal transduction
GO:0009749 - response to glucose

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

666184

SHC1
SHC-transforming protein 1

2

20

High-throughput

0.811

High

1139217

DAB2P
Disabled homolog 2-interacting protein

2

13

High-throughput

0.789

High

1299782

SYGP1
Ras/Rap GTPase-activating protein SynGAP

2

14

High-throughput

0.776

High

350662

RASK
GTPase KRas

2

20

High-throughput

0.754

High

916057

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.754

High

905231

1433G
14-3-3 protein gamma

6

20

High-throughput

0.735

High

822192

KC1A
Casein kinase I isoform alpha

5

7

High-throughput

0.725

High

683798

1433B
14-3-3 protein beta/alpha

5

20

High-throughput

0.716

High

647363

1433T
14-3-3 protein theta

4

20

High-throughput

0.699

High

982601

1433F
14-3-3 protein eta

4

20

High-throughput

0.699

High

617702

CRCM
Colorectal mutant cancer protein

4

7

High-throughput

0.692

High

830500

KC1E
Casein kinase I isoform epsilon

3

16

High-throughput

0.675

High

927633

1433Z
14-3-3 protein zeta/delta

3

20

High-throughput

0.650

High

120704

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

348993

RASN
GTPase NRas

1

20

High-throughput

0.618

High

349718

RASH
GTPase HRas

1

20

High-throughput

0.618

High

411884

LCK
Tyrosine-protein kinase Lck

1

19

High-throughput

0.618

High

434065

LYN
Tyrosine-protein kinase Lyn

1

20

High-throughput

0.618

High

436564

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.618

High

545691

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.618

High

564728

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.618

High

598538

NF1
Neurofibromin

1

14

High-throughput

0.618

High

845335

RAB7A
Ras-related protein Rab-7a

1

6

High-throughput

0.618

High

845798

RAB9A
Ras-related protein Rab-9A

1

11

High-throughput

0.618

High

852669

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.618

High

892671

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

894568

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.618

High

895315

RAB2A
Ras-related protein Rab-2A

1

9

High-throughput

0.618

High

901032

RHOA
Transforming protein RhoA

1

20

High-throughput

0.618

High

901267

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.618

High

914440

RB11A
Ras-related protein Rab-11A

1

3

High-throughput

0.618

High

925715

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

951447

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.618

High

1070446

RAB35
Ras-related protein Rab-35

1

10

High-throughput

0.618

High

1076808

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.618

High

1183601

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.618

High

1269248

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.618

High

1335382

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.618

High

1355995

AGAP1
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1

1

20

High-throughput

0.618

High

910133

1433E
14-3-3 protein epsilon

2

6

High-throughput

0.611

High

1076394

IKBB
NF-kappa-B inhibitor beta

2

11

High-throughput

0.611

High

213052

STX6
Syntaxin-6

1

0

High-throughput

0.586

High

1023835

TRAF1
TNF receptor-associated factor 1

1

4

High-throughput

0.573

High

178852

STX7
Syntaxin-7

1

1

High-throughput

0.553

High

318244

DIRA3
GTP-binding protein Di-Ras3

1

11

High-throughput

0.553

High

1296759

RHOV
Rho-related GTP-binding protein RhoV

1

20

High-throughput

0.553

High

1330979

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.553

High

203258

SYNJ1
Synaptojanin-1

1

2

High-throughput

0.541

High

822398

KC1D
Casein kinase I isoform delta

1

5

High-throughput

0.536

High

871822

HSP72
Heat shock-related 70 kDa protein 2

1

4

High-throughput

0.536

High

1191813

ANS1B
Ankyrin repeat and sterile alpha motif domain-containing protein 1B

1

16

High-throughput

0.536

High

1236736

USBP1
Harmonin-binding protein USHBP1

1

9

High-throughput

0.523

High

324102

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.513

High

476536

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

4

High-throughput

0.501

High

149400

CTRO
Citron Rho-interacting kinase

1

5

High-throughput

0.479

High

196524

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

6

High-throughput

0.479

High

237338

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

1

High-throughput

0.479

High

253428

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

1

6

High-throughput

0.479

High

264433

GGYF1
GRB10-interacting GYF protein 1

1

4

High-throughput

0.479

High

302033

TRI37
E3 ubiquitin-protein ligase TRIM37

1

10

High-throughput

0.479

High

316285

NADK
NAD kinase

1

1

High-throughput

0.479

High

377788

GCR
Glucocorticoid receptor

1

8

High-throughput

0.479

High

507301

LAMP1
Lysosome-associated membrane glycoprotein 1

1

1

High-throughput

0.479

High

508255

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.479

High

547269

EZRI
Ezrin

1

6

High-throughput

0.479

High

567320

CXA1
Gap junction alpha-1 protein

1

2

High-throughput

0.479

High

568822

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

9

High-throughput

0.479

High

673531

MPIP2
M-phase inducer phosphatase 2

1

3

High-throughput

0.479

High

673637

MPIP3
M-phase inducer phosphatase 3

1

3

High-throughput

0.479

High

684382

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

835556

GSK3A
Glycogen synthase kinase-3 alpha

1

10

High-throughput

0.479

High

836071

GSK3B
Glycogen synthase kinase-3 beta

1

11

High-throughput

0.479

High

876532

AFAD
Afadin

1

20

High-throughput

0.479

High

880844

HDAC4
Histone deacetylase 4

1

5

High-throughput

0.479

High

913172

ARF6
ADP-ribosylation factor 6

1

8

High-throughput

0.479

High

960422

CDK16
Cyclin-dependent kinase 16

1

5

High-throughput

0.479

High

997233

CAMP2
Calmodulin-regulated spectrin-associated protein 2

1

10

High-throughput

0.479

High

1022468

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

7

High-throughput

0.479

High

1036184

BIRC3
Baculoviral IAP repeat-containing protein 3

1

3

High-throughput

0.479

High

1066841

KIF14
Kinesin-like protein KIF14

1

7

High-throughput

0.479

High

1110123

AR13B
ADP-ribosylation factor-like protein 13B

1

12

High-throughput

0.479

High

1136489

M3K21
Mitogen-activated protein kinase kinase kinase 21

1

4

High-throughput

0.479

High

1136558

SPD2A
SH3 and PX domain-containing protein 2A

1

8

High-throughput

0.479

High

1139647

DEN4C
DENN domain-containing protein 4C

1

5

High-throughput

0.479

High

1153437

PKHA7
Pleckstrin homology domain-containing family A member 7

1

14

High-throughput

0.479

High

1168005

GGYF2
GRB10-interacting GYF protein 2

1

12

High-throughput

0.479

High

1173160

SYDE1
Rho GTPase-activating protein SYDE1

1

9

High-throughput

0.479

High

1197848

PHLB2
Pleckstrin homology-like domain family B member 2

1

11

High-throughput

0.479

High

1217997

KSR1
Kinase suppressor of Ras 1

1

19

High-throughput

0.479

High

1230420

CXD3
Gap junction delta-3 protein

1

2

High-throughput

0.479

High

1253343

F110B
Protein FAM110B

1

1

High-throughput

0.479

High

1256265

DEN1A
DENN domain-containing protein 1A

1

7

High-throughput

0.479

High

1256915

PARD3
Partitioning defective 3 homolog

1

17

High-throughput

0.479

High

1285215

SH3K1
SH3 domain-containing kinase-binding protein 1

1

12

High-throughput

0.479

High

1296951

SNX27
Sorting nexin-27

1

14

High-throughput

0.479

High

1300689

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

1

20

High-throughput

0.479

High

1308731

SIN1
Target of rapamycin complex 2 subunit MAPKAP1

1

1

High-throughput

0.479

High

1311607

RTKN
Rhotekin

1

1

High-throughput

0.479

High

1330433

DNJC5
DnaJ homolog subfamily C member 5

1

1

High-throughput

0.479

High

1336728

MYO10
Unconventional myosin-X

1

8

Small-scale

0.479

High

1343630

KI13B
Kinesin-like protein KIF13B

1

7

High-throughput

0.479

High

1343764

ANLN
Anillin

1

4

High-throughput

0.479

High

1344962

LATS2
Serine/threonine-protein kinase LATS2

1

7

High-throughput

0.479

High

1345062

INP5E
Phosphatidylinositol polyphosphate 5-phosphatase type IV

1

5

High-throughput

0.479

High

1355272

LIMA1
LIM domain and actin-binding protein 1

1

9

High-throughput

0.479

High

1355992

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

1

2

High-throughput

0.479

High

1355993

ZBT21
Zinc finger and BTB domain-containing protein 21

1

2

High-throughput

0.479

High

1355996

CBY1
Protein chibby homolog 1

1

2

High-throughput

0.479

High

1151293

Q6FHY5
MEOX2 protein

1

4

High-throughput

0.470

High

1299189

MIA2
Melanoma inhibitory activity protein 2

1

9

High-throughput

0.470

High

449835

HMGB1
High mobility group protein B1

1

3

Small-scale

0.464

High

1302349

CK5P2
CDK5 regulatory subunit-associated protein 2

1

12

High-throughput

0.445

High

838346

MEOX2
Homeobox protein MOX-2

1

4

High-throughput

0.439

High

101265

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

166625

DCLK1
Serine/threonine-protein kinase DCLK1

1

17

High-throughput

0.437

High

216985

KIF1C
Kinesin-like protein KIF1C

1

7

High-throughput

0.437

High

230926

MAST3
Microtubule-associated serine/threonine-protein kinase 3

1

8

High-throughput

0.437

High

279753

FLOT1
Flotillin-1

1

6

High-throughput

0.437

High

348182

MYC
Myc proto-oncogene protein

1

6

High-throughput

0.437

High

670273

MARCS
Myristoylated alanine-rich C-kinase substrate

1

5

High-throughput

0.437

High

721728

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.437

High

793514

MUC18
Cell surface glycoprotein MUC18

1

8

High-throughput

0.437

High

940596

CXAR
Coxsackievirus and adenovirus receptor

1

6

High-throughput

0.437

High

975101

CAV1
Caveolin-1

1

6

High-throughput

0.437

High

1060643

ZN638
Zinc finger protein 638

1

3

High-throughput

0.437

High

1072624

EPHA7
Ephrin type-A receptor 7

1

13

High-throughput

0.437

High

1084232

OCLN
Occludin

1

2

High-throughput

0.437

High

1148260

RNF43
E3 ubiquitin-protein ligase RNF43

1

3

High-throughput

0.437

High

1149009

AN34A
Ankyrin repeat domain-containing protein 34A

1

14

High-throughput

0.437

High

1152172

LTOR1
Ragulator complex protein LAMTOR1

1

3

High-throughput

0.437

High

1172184

TRI67
Tripartite motif-containing protein 67

1

9

High-throughput

0.437

High

1172786

CE128
Centrosomal protein of 128 kDa

1

8

High-throughput

0.437

High

1203949

RGPS2
Ras-specific guanine nucleotide-releasing factor RalGPS2

1

2

High-throughput

0.437

High

1263472

SRS12
Serine/arginine-rich splicing factor 12

1

7

High-throughput

0.437

High

1283093

CK052
Uncharacterized protein C11orf52

1

4

High-throughput

0.437

High

1297944

HS12B
Heat shock 70 kDa protein 12B

1

1

High-throughput

0.437

High

1301721

TESK2
Dual specificity testis-specific protein kinase 2

1

3

High-throughput

0.437

High

1309748

LPIN3
Phosphatidate phosphatase LPIN3

1

1

High-throughput

0.437

High

1336473

E41LA
Band 4.1-like protein 4A

1

7

High-throughput

0.437

High

1348454

FA53C
Protein FAM53C

1

1

High-throughput

0.437

High

1350020

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

1

3

High-throughput

0.437

High

1350449

CING
Cingulin

1

8

High-throughput

0.437

High

1355994

PPM1H
Protein phosphatase 1H

1

1

High-throughput

0.437

High

1355997

KCTD3
BTB/POZ domain-containing protein KCTD3

1

2

High-throughput

0.437

High

240243

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

3

High-throughput

0.407

High

132629

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

0

High-throughput

0.249

Low

305674

ZFPL1
Zinc finger protein-like 1

1

0

High-throughput

0.249

Low

648920

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.249

Low

825592

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.249

Low

1203895

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024