Protein: ZBT21
Zinc finger and BTB domain-containing protein 21 (Zinc finger protein 295)

Gene: ZBT21, ZBTB21
Organism: Homo sapiens
Interactions: 160
UniProt ID: Q9ULJ3

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1262093

KBTB7
Kelch repeat and BTB domain-containing protein 7

2

3

High-throughput

0.811

High

1281636

ABTB1
Ankyrin repeat and BTB/POZ domain-containing protein 1

2

1

High-throughput

0.811

High

905244

1433G
14-3-3 protein gamma

6

11

High-throughput

0.735

High

647373

1433T
14-3-3 protein theta

4

11

High-throughput

0.699

High

683806

1433B
14-3-3 protein beta/alpha

4

11

High-throughput

0.699

High

982611

1433F
14-3-3 protein eta

4

11

High-throughput

0.699

High

1044737

FHL3
Four and a half LIM domains protein 3

3

4

High-throughput

0.667

High

1146395

2ABD
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

2

2

High-throughput

0.628

High

215937

ZBT14
Zinc finger and BTB domain-containing protein 14

1

20

Small-scale

0.618

High

822195

KC1A
Casein kinase I isoform alpha

1

2

High-throughput

0.618

High

960424

CDK16
Cyclin-dependent kinase 16

1

3

High-throughput

0.618

High

1042825

CUL3
Cullin-3

1

20

High-throughput

0.618

High

1300885

PASK
PAS domain-containing serine/threonine-protein kinase

1

1

High-throughput

0.618

High

1356890

ZBT21
Zinc finger and BTB domain-containing protein 21

1

5

Small-scale

0.618

High

910146

1433E
14-3-3 protein epsilon

2

1

High-throughput

0.611

High

927648

1433Z
14-3-3 protein zeta/delta

2

11

High-throughput

0.611

High

1298864

NP1L5
Nucleosome assembly protein 1-like 5

2

1

High-throughput

0.611

High

159745

CASQ2
Calsequestrin-2

3

3

High-throughput

0.609

High

1016748

CETN1
Centrin-1

2

0

High-throughput

0.602

High

154266

CHK1
Serine/threonine-protein kinase Chk1

1

0

High-throughput

0.586

High

1222636

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.586

High

439296

GSTA1
Glutathione S-transferase A1

2

0

High-throughput

0.585

High

1354640

FXL17
F-box/LRR-repeat protein 17

1

1

High-throughput

0.575

High

217065

PRIC3
Prickle planar cell polarity protein 3

2

3

High-throughput

0.574

High

166628

DCLK1
Serine/threonine-protein kinase DCLK1

1

1

High-throughput

0.553

High

230930

MAST3
Microtubule-associated serine/threonine-protein kinase 3

1

3

High-throughput

0.553

High

1287283

KLH29
Kelch-like protein 29

1

1

High-throughput

0.553

High

1291604

OTUB1
Ubiquitin thioesterase OTUB1

2

0

High-throughput

0.547

High

380879

S100B
Protein S100-B

1

3

High-throughput

0.536

High

418783

NPM
Nucleophosmin

1

8

High-throughput

0.536

High

557002

CREB1
Cyclic AMP-responsive element-binding protein 1

1

1

High-throughput

0.536

High

958790

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

2

High-throughput

0.536

High

980573

NOTC2
Neurogenic locus notch homolog protein 2

1

13

High-throughput

0.536

High

1239032

TEX19
Testis-expressed protein 19

1

1

High-throughput

0.536

High

1057211

MELK
Maternal embryonic leucine zipper kinase

1

0

High-throughput

0.517

High

361251

TNNC2
Troponin C, skeletal muscle

1

0

High-throughput

0.513

High

862316

NUBP1
Cytosolic Fe-S cluster assembly factor NUBP1

1

0

High-throughput

0.513

High

880368

DPOE2
DNA polymerase epsilon subunit 2

1

0

High-throughput

0.513

High

899079

PSME3
Proteasome activator complex subunit 3

1

0

High-throughput

0.513

High

934022

TBB4B
Tubulin beta-4B chain

1

0

High-throughput

0.513

High

1029352

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

0

High-throughput

0.513

High

661478

S10A2
Protein S100-A2

1

3

High-throughput

0.489

High

232582

KDM1A
Lysine-specific histone demethylase 1A

1

4

High-throughput

0.479

High

245083

BRD4
Bromodomain-containing protein 4

1

2

High-throughput

0.479

High

253430

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

1

11

High-throughput

0.479

High

264438

GGYF1
GRB10-interacting GYF protein 1

1

2

High-throughput

0.479

High

319376

BRD1
Bromodomain-containing protein 1

1

2

High-throughput

0.479

High

387717

P53
Cellular tumor antigen p53

1

6

High-throughput

0.479

High

455988

PARP1
Poly [ADP-ribose] polymerase 1

1

2

High-throughput

0.479

High

487831

ANDR
Androgen receptor

1

11

High-throughput

0.479

High

554038

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

598542

NF1
Neurofibromin

1

2

High-throughput

0.479

High

652587

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

673534

MPIP2
M-phase inducer phosphatase 2

1

1

High-throughput

0.479

High

673639

MPIP3
M-phase inducer phosphatase 3

1

1

High-throughput

0.479

High

684389

1433S
14-3-3 protein sigma

1

11

High-throughput

0.479

High

721759

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

750531

COIL
Coilin

1

3

High-throughput

0.479

High

782690

HNF4A
Hepatocyte nuclear factor 4-alpha

1

5

High-throughput

0.479

High

799035

GATA4
Transcription factor GATA-4

1

1

High-throughput

0.479

High

802518

ATRX
Transcriptional regulator ATRX

1

3

Small-scale

0.479

High

831787

CEBPA
CCAAT/enhancer-binding protein alpha

1

6

High-throughput

0.479

High

876535

AFAD
Afadin

1

5

High-throughput

0.479

High

880851

HDAC4
Histone deacetylase 4

1

6

High-throughput

0.479

High

902806

SUMO2
Small ubiquitin-related modifier 2

1

5

Small-scale

0.479

High

952696

H33
Histone H3.3

1

8

High-throughput

0.479

High

971829

HEN1
Helix-loop-helix protein 1

1

3

High-throughput

0.479

High

997235

CAMP2
Calmodulin-regulated spectrin-associated protein 2

1

1

High-throughput

0.479

High

1014220

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

1

2

High-throughput

0.479

High

1020236

PTN13
Tyrosine-protein phosphatase non-receptor type 13

1

1

High-throughput

0.479

High

1022471

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

2

High-throughput

0.479

High

1027325

CBX3
Chromobox protein homolog 3

1

20

High-throughput

0.479

High

1038813

HDAC1
Histone deacetylase 1

1

4

High-throughput

0.479

High

1060646

ZN638
Zinc finger protein 638

1

1

High-throughput

0.479

High

1076939

PTN14
Tyrosine-protein phosphatase non-receptor type 14

1

1

High-throughput

0.479

High

1120157

CRTC2
CREB-regulated transcription coactivator 2

1

5

High-throughput

0.479

High

1136560

SPD2A
SH3 and PX domain-containing protein 2A

1

2

High-throughput

0.479

High

1139651

DEN4C
DENN domain-containing protein 4C

1

2

High-throughput

0.479

High

1153445

PKHA7
Pleckstrin homology domain-containing family A member 7

1

16

High-throughput

0.479

High

1161849

FBX38
F-box only protein 38

1

1

High-throughput

0.479

High

1164923

CRTC3
CREB-regulated transcription coactivator 3

1

1

High-throughput

0.479

High

1168009

GGYF2
GRB10-interacting GYF protein 2

1

3

High-throughput

0.479

High

1189028

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.479

High

1189739

MYCPP
C-myc promoter-binding protein

1

2

High-throughput

0.479

High

1197852

PHLB2
Pleckstrin homology-like domain family B member 2

1

2

High-throughput

0.479

High

1200750

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

1217999

KSR1
Kinase suppressor of Ras 1

1

6

High-throughput

0.479

High

1230066

RPTOR
Regulatory-associated protein of mTOR

1

1

High-throughput

0.479

High

1253345

F110B
Protein FAM110B

1

1

High-throughput

0.479

High

1256267

DEN1A
DENN domain-containing protein 1A

1

2

High-throughput

0.479

High

1256286

SH3R3
E3 ubiquitin-protein ligase SH3RF3

1

3

High-throughput

0.479

High

1260201

HDAC7
Histone deacetylase 7

1

6

High-throughput

0.479

High

1300692

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

1

1

High-throughput

0.479

High

1300992

CIC
Protein capicua homolog

1

5

High-throughput

0.479

High

1309183

F110A
Protein FAM110A

1

1

High-throughput

0.479

High

1328300

CCDC8
Coiled-coil domain-containing protein 8

1

2

High-throughput

0.479

High

1334858

PKHA5
Pleckstrin homology domain-containing family A member 5

1

15

High-throughput

0.479

High

1347415

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

1

High-throughput

0.479

High

1355275

LIMA1
LIM domain and actin-binding protein 1

1

1

High-throughput

0.479

High

1355993

NGAP
Ras GTPase-activating protein nGAP

1

2

High-throughput

0.479

High

1356484

RCOR1
REST corepressor 1

1

4

High-throughput

0.479

High

1356892

AGAP1
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1

1

2

High-throughput

0.479

High

1356893

BAIP2
BAR/IMD domain-containing adapter protein 2

1

1

High-throughput

0.479

High

1356894

GAB2
GRB2-associated-binding protein 2

1

14

High-throughput

0.479

High

1356895

HDAC5
Histone deacetylase 5

1

6

High-throughput

0.479

High

1356898

STA13
StAR-related lipid transfer protein 13

1

3

High-throughput

0.479

High

1356899

ZN330
Zinc finger protein 330

1

1

High-throughput

0.479

High

237342

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

0

High-throughput

0.458

High

314699

PARN
Poly(A)-specific ribonuclease PARN

1

0

High-throughput

0.458

High

316288

NADK
NAD kinase

1

0

High-throughput

0.458

High

1162711

LARP1
La-related protein 1

1

0

High-throughput

0.458

High

1172946

FGD6
FYVE, RhoGEF and PH domain-containing protein 6

1

0

High-throughput

0.458

High

1185273

RFIP2
Rab11 family-interacting protein 2

1

0

High-throughput

0.458

High

1198513

TBCD1
TBC1 domain family member 1

1

0

High-throughput

0.458

High

1232343

MILK1
MICAL-like protein 1

1

0

High-throughput

0.458

High

1263476

SRS12
Serine/arginine-rich splicing factor 12

1

0

High-throughput

0.458

High

1288381

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

0

High-throughput

0.458

High

1291008

EDC3
Enhancer of mRNA-decapping protein 3

1

0

High-throughput

0.458

High

1301723

TESK2
Dual specificity testis-specific protein kinase 2

1

0

High-throughput

0.458

High

1308733

SIN1
Target of rapamycin complex 2 subunit MAPKAP1

1

0

High-throughput

0.458

High

1309749

LPIN3
Phosphatidate phosphatase LPIN3

1

0

High-throughput

0.458

High

1311609

RTKN
Rhotekin

1

0

High-throughput

0.458

High

1317674

PANK2
Pantothenate kinase 2, mitochondrial

1

0

High-throughput

0.458

High

1318036

OSBL6
Oxysterol-binding protein-related protein 6

1

0

High-throughput

0.458

High

1342888

DCP1A
mRNA-decapping enzyme 1A

1

0

High-throughput

0.458

High

1345063

INP5E
Phosphatidylinositol polyphosphate 5-phosphatase type IV

1

0

High-throughput

0.458

High

1347940

CWC25
Pre-mRNA-splicing factor CWC25 homolog

1

0

High-throughput

0.458

High

1348384

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

1348456

FA53C
Protein FAM53C

1

0

High-throughput

0.458

High

1349856

SH3B4
SH3 domain-binding protein 4

1

0

High-throughput

0.458

High

1354406

ZMYM2
Zinc finger MYM-type protein 2

1

0

High-throughput

0.458

High

1356315

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

1

0

High-throughput

0.458

High

1356891

PPM1H
Protein phosphatase 1H

1

0

High-throughput

0.458

High

1356897

CBY1
Protein chibby homolog 1

1

0

High-throughput

0.458

High

101280

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

216988

KIF1C
Kinesin-like protein KIF1C

1

3

High-throughput

0.437

High

231763

KIF1B
Kinesin-like protein KIF1B

1

3

High-throughput

0.437

High

995297

GOGA2
Golgin subfamily A member 2

1

4

High-throughput

0.437

High

1109700

TBC25
TBC1 domain family member 25

1

1

High-throughput

0.437

High

1136491

M3K21
Mitogen-activated protein kinase kinase kinase 21

1

2

High-throughput

0.437

High

1149011

AN34A
Ankyrin repeat domain-containing protein 34A

1

14

High-throughput

0.437

High

1173162

SYDE1
Rho GTPase-activating protein SYDE1

1

13

High-throughput

0.437

High

1243700

NAV1
Neuron navigator 1

1

1

High-throughput

0.437

High

1260798

DEP1B
DEP domain-containing protein 1B

1

13

High-throughput

0.437

High

1335967

TANC2
Protein TANC2

1

3

High-throughput

0.437

High

1343632

KI13B
Kinesin-like protein KIF13B

1

3

High-throughput

0.437

High

225078

ZNRD2
Protein ZNRD2

1

0

High-throughput

0.279

Low

640034

PTX3
Pentraxin-related protein PTX3

1

0

High-throughput

0.279

Low

1233812

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

0

High-throughput

0.279

Low

1356896

CLC11
C-type lectin domain family 11 member A

1

0

High-throughput

0.279

Low

196528

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

0

High-throughput

0.249

Low

928712

DYLT1
Dynein light chain Tctex-type 1

1

0

High-throughput

0.249

Low

1156247

REEP3
Receptor expression-enhancing protein 3

1

0

High-throughput

0.249

Low

1203950

RGPS2
Ras-specific guanine nucleotide-releasing factor RalGPS2

1

0

High-throughput

0.249

Low

1284908

DACT3
Dapper homolog 3

1

0

High-throughput

0.249

Low

1327091

MFR1L
Mitochondrial fission regulator 1-like

1

0

High-throughput

0.249

Low

1350022

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

1

0

High-throughput

0.249

Low

1350450

CING
Cingulin

1

0

High-throughput

0.249

Low

1356900

KCTD3
BTB/POZ domain-containing protein KCTD3

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024