Protein: T22D4
TSC22 domain family protein 4 (TSC22-related-inducible leucine zipper protein 2)

Gene: T22D4, TSC22D4
Organism: Homo sapiens
Interactions: 122
UniProt ID: Q9Y3Q8

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006970 - response to osmotic stress
GO:0030425 - dendrite

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

256841

T22D2
TSC22 domain family protein 2

3

14

High-throughput

0.861

High

1077370

T22D1
TSC22 domain family protein 1

3

14

High-throughput

0.861

High

1304685

T22D3
TSC22 domain family protein 3

3

10

High-throughput

0.861

High

1355633

NRBP
Nuclear receptor-binding protein

10

17

Small-scale

0.759

High

1345645

NRBP2
Nuclear receptor-binding protein 2

5

20

High-throughput

0.726

High

1049362

KEAP1
Kelch-like ECH-associated protein 1

5

2

Small-scale

0.713

High

1029364

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

5

0

High-throughput

0.696

High

1038094

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

5

0

High-throughput

0.692

High

196692

ZBT24
Zinc finger and BTB domain-containing protein 24

3

1

High-throughput

0.675

High

245651

TBL1X
F-box-like/WD repeat-containing protein TBL1X

3

4

High-throughput

0.667

High

901079

RHOA
Transforming protein RhoA

3

8

High-throughput

0.667

High

1241819

PDPR
Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial

3

1

High-throughput

0.667

High

1317207

WNK3
Serine/threonine-protein kinase WNK3

3

17

High-throughput

0.667

High

1318261

KPCD2
Serine/threonine-protein kinase D2

3

2

High-throughput

0.667

High

1330751

WNK1
Serine/threonine-protein kinase WNK1

3

19

High-throughput

0.667

High

1354609

STK39
STE20/SPS1-related proline-alanine-rich protein kinase

3

2

High-throughput

0.667

High

1356378

FBW1B
F-box/WD repeat-containing protein 11

3

3

High-throughput

0.667

High

1377160

FBW1A
F-box/WD repeat-containing protein 1A

3

4

High-throughput

0.667

High

1377724

WNK2
Serine/threonine-protein kinase WNK2

3

18

High-throughput

0.667

High

169998

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

3

0

High-throughput

0.646

High

854155

GDS1
Rap1 GTPase-GDP dissociation stimulator 1

3

0

High-throughput

0.638

High

1062978

MD2BP
MAD2L1-binding protein

3

0

High-throughput

0.638

High

275354

ZMY10
Zinc finger MYND domain-containing protein 10

2

0

High-throughput

0.629

High

1281209

LHX4
LIM/homeobox protein Lhx4

2

4

High-throughput

0.628

High

1347335

PIHD1
PIH1 domain-containing protein 1

2

0

High-throughput

0.618

High

1292945

MTNB
Methylthioribulose-1-phosphate dehydratase

2

0

High-throughput

0.616

High

1041297

CUL1
Cullin-1

2

5

High-throughput

0.611

High

1104107

P3H1
Prolyl 3-hydroxylase 1

2

2

High-throughput

0.611

High

1318191

TBL1R
F-box-like/WD repeat-containing protein TBL1XR1

2

3

High-throughput

0.611

High

274455

CRTAP
Cartilage-associated protein

3

2

High-throughput

0.609

High

532256

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

3

1

High-throughput

0.609

High

638596

RBTN1
Rhombotin-1

2

3

High-throughput

0.606

High

453729

ROA1
Heterogeneous nuclear ribonucleoprotein A1

2

8

High-throughput

0.601

High

1354662

LRWD1
Leucine-rich repeat and WD repeat-containing protein 1

2

0

High-throughput

0.585

High

325470

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

1

High-throughput

0.582

High

901763

PFD3
Prefoldin subunit 3

2

0

High-throughput

0.580

High

1310481

RHG09
Rho GTPase-activating protein 9

2

0

High-throughput

0.580

High

1335797

CBX8
Chromobox protein homolog 8

2

0

High-throughput

0.580

High

950339

SMAD3
Mothers against decapentaplegic homolog 3

1

2

High-throughput

0.573

High

1072084

PCBP1
Poly(rC)-binding protein 1

1

1

High-throughput

0.573

High

234308

PEPL
Periplakin

1

2

High-throughput

0.573

High

638433

RBTN2
Rhombotin-2

1

3

High-throughput

0.573

High

871507

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

1

1

High-throughput

0.573

High

1025245

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

1

High-throughput

0.573

High

1223061

CC146
Coiled-coil domain-containing protein 146

1

1

High-throughput

0.573

High

1223147

TEX11
Testis-expressed protein 11

2

1

High-throughput

0.559

High

1330073

CPVL
Probable serine carboxypeptidase CPVL

2

2

High-throughput

0.558

High

1354319

CTNL1
Alpha-catulin

2

1

High-throughput

0.553

High

150645

ABLM1
Actin-binding LIM protein 1

1

6

High-throughput

0.541

High

277552

CCNK
Cyclin-K

1

2

High-throughput

0.541

High

637615

PSA1
Proteasome subunit alpha type-1

1

4

High-throughput

0.541

High

929739

RACK1
Small ribosomal subunit protein RACK1

1

5

High-throughput

0.541

High

1252568

LNX1
E3 ubiquitin-protein ligase LNX

1

5

High-throughput

0.541

High

1281504

FBXW7
F-box/WD repeat-containing protein 7

1

3

High-throughput

0.541

High

1282079

TRI63
E3 ubiquitin-protein ligase TRIM63

1

7

High-throughput

0.541

High

1298655

FRMD6
FERM domain-containing protein 6

1

4

High-throughput

0.541

High

1317548

TRI55
Tripartite motif-containing protein 55

1

7

High-throughput

0.541

High

1356280

ZN580
Zinc finger protein 580

1

1

High-throughput

0.541

High

156381

PSA7
Proteasome subunit alpha type-7

1

4

High-throughput

0.536

High

264254

CDC45
Cell division control protein 45 homolog

1

1

High-throughput

0.536

High

1342217

WDR6
tRNA

1

7

High-throughput

0.536

High

1264348

MYLIP
E3 ubiquitin-protein ligase MYLIP

1

4

High-throughput

0.523

High

500919

CLUS
Clusterin

1

0

High-throughput

0.518

High

836629

MTHFS
5-formyltetrahydrofolate cyclo-ligase

1

0

High-throughput

0.518

High

844296

FXR2
RNA-binding protein FXR2

1

0

High-throughput

0.518

High

1017265

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

0

High-throughput

0.518

High

1067711

CD5R1
Cyclin-dependent kinase 5 activator 1

1

0

High-throughput

0.518

High

1262007

UBCP1
Ubiquitin-like domain-containing CTD phosphatase 1

1

0

High-throughput

0.518

High

1326647

NIF3L
NIF3-like protein 1

1

0

High-throughput

0.518

High

1349201

SACS
Sacsin

1

0

High-throughput

0.518

High

231774

KIF1B
Kinesin-like protein KIF1B

1

1

High-throughput

0.515

High

388820

HSPB1
Heat shock protein beta-1

1

4

High-throughput

0.515

High

1295660

MY15B
Unconventional myosin-XVB

1

1

High-throughput

0.515

High

1357350

UBQL1
Ubiquilin-1

1

3

High-throughput

0.515

High

1377635

RNF11
RING finger protein 11

1

1

High-throughput

0.515

High

215173

LANC1
Glutathione S-transferase LANCL1

1

0

High-throughput

0.513

High

1063134

ABRX2
BRISC complex subunit Abraxas 2

1

0

High-throughput

0.513

High

1298664

ZN558
Zinc finger protein 558

1

0

High-throughput

0.513

High

1313887

NOC4L
Nucleolar complex protein 4 homolog

1

1

High-throughput

0.494

High

1333965

GORS2
Golgi reassembly-stacking protein 2

1

4

High-throughput

0.494

High

281961

WFS1
Wolframin

1

0

High-throughput

0.493

High

657992

CLAT
Choline O-acetyltransferase

1

0

High-throughput

0.493

High

1217654

P3H2
Prolyl 3-hydroxylase 2

1

2

High-throughput

0.489

High

1345407

CAH10
Carbonic anhydrase-related protein 10

1

1

High-throughput

0.489

High

1357923

SH2B3
SH2B adapter protein 3

1

7

High-throughput

0.489

High

305122

RIMB1
Peripheral-type benzodiazepine receptor-associated protein 1

1

3

High-throughput

0.481

High

993655

TLE5
TLE family member 5

1

3

High-throughput

0.481

High

1329414

GO45
Golgin-45

1

1

High-throughput

0.481

High

568842

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

4

High-throughput

0.479

High

610122

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

8

High-throughput

0.479

High

905295

1433G
14-3-3 protein gamma

1

15

High-throughput

0.479

High

927695

1433Z
14-3-3 protein zeta/delta

1

15

High-throughput

0.479

High

982651

1433F
14-3-3 protein eta

1

15

High-throughput

0.479

High

609626

FGFR3
Fibroblast growth factor receptor 3

1

2

High-throughput

0.470

High

853527

IMA1
Importin subunit alpha-1

1

0

High-throughput

0.460

High

796817

RANG
Ran-specific GTPase-activating protein

1

0

High-throughput

0.458

High

378224

PRIO
Major prion protein

1

1

High-throughput

0.457

High

101308

APRIO
Alternative prion protein

1

2

High-throughput

0.439

High

995329

GOGA2
Golgin subfamily A member 2

1

2

High-throughput

0.439

High

1149408

K1C40
Keratin, type I cytoskeletal 40

1

1

High-throughput

0.439

High

180108

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

1

1

High-throughput

0.437

High

1072338

ELOC
Elongin-C

1

1

High-throughput

0.437

High

1072491

ELOB
Elongin-B

1

2

High-throughput

0.437

High

1222046

MILK2
MICAL-like protein 2

1

4

High-throughput

0.437

High

1354697

IF172
Intraflagellar transport protein 172 homolog

1

3

High-throughput

0.437

High

1377726

X5D7U3
Benzodiazapine receptor peripheral-associated protein 1 isoform K

1

2

High-throughput

0.417

High

1356125

CDC23
Cell division cycle protein 23 homolog

3

0

High-throughput

0.348

High

1245375

TTL
Tubulin--tyrosine ligase

3

0

High-throughput

0.347

High

158342

PCD17
Protocadherin-17

2

0

High-throughput

0.316

High

600076

SAT1
Diamine acetyltransferase 1

1

0

High-throughput

0.282

High

706819

CKS2
Cyclin-dependent kinases regulatory subunit 2

1

0

High-throughput

0.282

High

1235142

CCD33
Coiled-coil domain-containing protein 33

1

0

High-throughput

0.282

High

1297693

CCD42
Coiled-coil domain-containing protein 42

1

0

High-throughput

0.282

High

1311668

SYT17
Synaptotagmin-17

1

0

High-throughput

0.282

High

1327858

ENKD1
Enkurin domain-containing protein 1

1

0

High-throughput

0.282

High

402765

RPC4
DNA-directed RNA polymerase III subunit RPC4

1

0

High-throughput

0.279

Low

880334

TCL1A
T-cell leukemia/lymphoma protein 1A

1

0

High-throughput

0.279

Low

1138800

SPO16
Protein SPO16 homolog

1

0

High-throughput

0.279

Low

660771

GRN
Progranulin

1

0

High-throughput

0.268

Low

1377725

Q9Y649
GW128

1

0

High-throughput

0.268

Low

576275

LBP
Lipopolysaccharide-binding protein

1

0

High-throughput

0.251

Low

1242023

SMG8
Nonsense-mediated mRNA decay factor SMG8

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024