Protein: POLK
DNA polymerase kappa (EC 2.7.7.7) (DINB protein) (DINP)

Gene: POLK
Organism: Homo sapiens
Interactions: 55
UniProt ID: Q9UBT6

Gene Ontology (top 5):
GO:0003684 - damaged DNA binding
GO:0003887 - DNA-directed DNA polymerase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1354315

REV1
DNA repair protein REV1

6

14

Small-scale

0.948

High

517517

PCNA
Proliferating cell nuclear antigen

5

14

Small-scale

0.920

High

1345448

RAD18
E3 ubiquitin-protein ligase RAD18

2

2

Small-scale

0.624

High

1235384

KCD17
BTB/POZ domain-containing protein KCTD17

3

2

High-throughput

0.609

High

1229732

SPART
Spartin

2

0

High-throughput

0.602

High

387659

P53
Cellular tumor antigen p53

2

3

High-throughput

0.584

High

278178

PIAS1
E3 SUMO-protein ligase PIAS1

1

3

High-throughput

0.536

High

988153

RAD51
DNA repair protein RAD51 homolog 1

1

1

High-throughput

0.536

High

1079022

UB2V2
Ubiquitin-conjugating enzyme E2 variant 2

1

2

High-throughput

0.536

High

1197596

PCGF5
Polycomb group RING finger protein 5

1

1

High-throughput

0.536

High

1314637

RBM4
RNA-binding protein 4

1

2

High-throughput

0.536

High

1315382

KLF16
Krueppel-like factor 16

1

1

High-throughput

0.536

High

1348075

KCTD5
BTB/POZ domain-containing protein KCTD5

1

2

High-throughput

0.536

High

538435

ENPL
Endoplasmin

1

4

High-throughput

0.515

High

1086339

H31T
Histone H3.1t

1

4

High-throughput

0.515

High

313363

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

1

0

High-throughput

0.513

High

786503

STAT6
Signal transducer and activator of transcription 6

1

0

High-throughput

0.513

High

1054645

RBM39
RNA-binding protein 39

1

0

High-throughput

0.513

High

1061089

NOLC1
Nucleolar and coiled-body phosphoprotein 1

1

0

High-throughput

0.513

High

1139529

TUT7
Terminal uridylyltransferase 7

1

0

High-throughput

0.513

High

1164894

FIP1
Pre-mRNA 3'-end-processing factor FIP1

1

0

High-throughput

0.513

High

1314737

RPAP1
RNA polymerase II-associated protein 1

1

0

High-throughput

0.513

High

1319430

BHE41
Class E basic helix-loop-helix protein 41

1

0

High-throughput

0.513

High

1336567

SRA1
Steroid receptor RNA activator 1

1

0

High-throughput

0.513

High

360504

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.493

High

502641

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.493

High

1255927

DTD1
D-aminoacyl-tRNA deacylase 1

1

0

High-throughput

0.493

High

1314602

TRAIP
E3 ubiquitin-protein ligase TRAIP

1

3

Small-scale

0.481

High

1050631

WRN
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN

1

0

Small-scale

0.480

High

579750

XRCC1
DNA repair protein XRCC1

1

1

Small-scale

0.479

High

658448

DPOD1
DNA polymerase delta catalytic subunit

1

4

Small-scale

0.479

High

669042

PML
Protein PML

1

1

High-throughput

0.479

High

680494

TIA1
Cytotoxic granule associated RNA binding protein TIA1

1

1

High-throughput

0.479

High

708536

MCM4
DNA replication licensing factor MCM4

1

1

Small-scale

0.479

High

794330

MSH2
DNA mismatch repair protein Msh2

1

3

Small-scale

0.479

High

855571

MSH6
DNA mismatch repair protein Msh6

1

3

Small-scale

0.479

High

952673

H33
Histone H3.3

1

4

High-throughput

0.479

High

1042746

CUL3
Cullin-3

1

2

High-throughput

0.479

High

1055649

MCM6
DNA replication licensing factor MCM6

1

1

Small-scale

0.479

High

1070801

RBBP5
Retinoblastoma-binding protein 5

1

1

High-throughput

0.479

High

1222618

SLX4
Structure-specific endonuclease subunit SLX4

1

1

High-throughput

0.479

High

1354317

SYNP2
Synaptopodin-2

1

1

High-throughput

0.479

High

1057248

KCTD2
BTB/POZ domain-containing protein KCTD2

1

2

High-throughput

0.470

High

652503

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

Small-scale

0.458

High

1161846

FBX38
F-box only protein 38

1

0

High-throughput

0.458

High

1354316

XPO7
Exportin-7

1

0

Small-scale

0.458

High

101784

F8W8I6
TIA1 cytotoxic granule associated RNA binding protein

1

1

High-throughput

0.445

High

108822

H0Y9Y3
Synaptopodin 2

1

1

High-throughput

0.445

High

111565

K7EK07
Histone H3

1

4

High-throughput

0.445

High

1335460

PARVG
Gamma-parvin

3

0

High-throughput

0.347

High

850508

PLXA3
Plexin-A3

1

0

High-throughput

0.279

Low

1165497

SBSN
Suprabasin

1

0

High-throughput

0.279

Low

1254113

C99L2
CD99 antigen-like protein 2

1

0

High-throughput

0.279

Low

1309579

APOL2
Apolipoprotein L2

1

0

High-throughput

0.279

Low

1315963

MAK16
Protein MAK16 homolog

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024