Protein: SOCS4
Suppressor of cytokine signaling 4 (SOCS-4) (Suppressor of cytokine signaling 7) (SOCS-7)

Gene: SOCS4
Organism: Homo sapiens
Interactions: 32
UniProt ID: Q8WXH5

Gene Ontology (top 5):
GO:0005942 - phosphatidylinositol 3-kinase complex
GO:0007175 - negative regulation of epidermal growth factor-activated receptor activity
GO:0016567 - protein ubiquitination
GO:0032436 - positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0035556 - intracellular signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1263831

CUL5
Cullin-5

4

20

High-throughput

0.895

High

1072259

ELOC
Elongin-C

3

10

Small-scale

0.821

High

1263830

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

2

20

High-throughput

0.819

High

924732

GRB2
Growth factor receptor-bound protein 2

2

20

High-throughput

0.732

High

992596

ACK1
Activated CDC42 kinase 1

2

20

High-throughput

0.686

High

1232485

PALS1
Protein PALS1

2

10

High-throughput

0.686

High

1263833

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

2

20

High-throughput

0.634

High

238424

JAK2
Tyrosine-protein kinase JAK2

1

20

Small-scale

0.618

High

499278

KIT
Mast/stem cell growth factor receptor Kit

1

20

Small-scale

0.618

High

338763

EGFR
Epidermal growth factor receptor

1

20

Small-scale

0.609

High

1072398

ELOB
Elongin-B

2

12

Small-scale

0.584

High

1263832

RET7
Retinoid-binding protein 7

2

2

High-throughput

0.579

High

207358

FRS3
Fibroblast growth factor receptor substrate 3

2

20

High-throughput

0.573

High

1262178

TEKT4
Tektin-4

2

2

High-throughput

0.553

High

1263837

RBX2
RING-box protein 2

1

11

High-throughput

0.536

High

103812

G5E9A7
DM1 locus, WD repeat containing

1

9

High-throughput

0.470

High

791812

HD
Huntingtin

1

7

High-throughput

0.470

High

1191496

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

14

High-throughput

0.470

High

1263746

JPH3
Junctophilin-3

1

2

High-throughput

0.470

High

208387

SPY1
Protein sprouty homolog 1

1

7

High-throughput

0.439

High

380918

VWF
von Willebrand factor

1

3

High-throughput

0.439

High

611475

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

19

High-throughput

0.439

High

1263836

MDFIC
MyoD family inhibitor domain-containing protein

1

1

High-throughput

0.439

High

1263838

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.437

High

276109

CNMD
Leukocyte cell-derived chemotaxin 1

2

0

High-throughput

0.310

High

1263834

LDH6B
L-lactate dehydrogenase A-like 6B

2

0

High-throughput

0.310

High

111328

J3KQ12
Seipin

1

0

High-throughput

0.268

Low

174119

SPTC1
Serine palmitoyltransferase 1

1

0

High-throughput

0.268

Low

204006

HTRA2
Serine protease HTRA2, mitochondrial

1

0

High-throughput

0.268

Low

782936

GARS
Glycine--tRNA ligase

1

0

High-throughput

0.268

Low

1263835

PANK2
Pantothenate kinase 2, mitochondrial

1

0

High-throughput

0.268

Low

1221931

PLPP6
Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024