Protein: ZBP1
Z-DNA-binding protein 1 (DNA-dependent activator of IFN-regulatory factors) (DAI) (Tumor stroma and activated macrophage protein DLM-1)

Gene: ZBP1
Organism: Homo sapiens
Interactions: 44
UniProt ID: Q9H171

Gene Ontology (top 5):
GO:0002218 - activation of innate immune response
GO:0003677 - DNA binding
GO:0003692 - left-handed Z-DNA binding
GO:0003723 - RNA binding
GO:0003725 - double-stranded RNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1328503

RIPK3
Receptor-interacting serine/threonine-protein kinase 3

4

3

Small-scale

0.878

High

1328497

ZBP1
Z-DNA-binding protein 1

2

1

Small-scale

0.776

High

1038318

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

4

4

Small-scale

0.674

High

881284

CTBP2
C-terminal-binding protein 2

1

1

High-throughput

0.578

High

1032604

CTBP1
C-terminal-binding protein 1

1

1

High-throughput

0.578

High

1024760

TRAF3
TNF receptor-associated factor 3

1

0

High-throughput

0.554

High

1317001

TRI34
E3 ubiquitin-protein ligase TRIM34

1

0

Small-scale

0.554

High

1328502

PALD
Paladin

1

0

High-throughput

0.554

High

315422

NSA2
Ribosome biogenesis protein NSA2 homolog

1

0

High-throughput

0.513

High

777732

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

1242748

ZN740
Zinc finger protein 740

1

0

High-throughput

0.513

High

232496

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.493

High

1268301

ZN516
Zinc finger protein 516

1

0

High-throughput

0.493

High

1300489

VPS35
Vacuolar protein sorting-associated protein 35

1

0

High-throughput

0.493

High

1328501

ORC3
Origin recognition complex subunit 3

1

0

High-throughput

0.493

High

791968

HD
Huntingtin

1

0

High-throughput

0.493

High

1076530

TRIP6
Thyroid receptor-interacting protein 6

1

1

High-throughput

0.481

High

1120812

KLH12
Kelch-like protein 12

1

1

High-throughput

0.481

High

1216709

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

2

High-throughput

0.481

High

158542

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

1

Small-scale

0.479

High

181642

CFLAR
CASP8 and FADD-like apoptosis regulator

1

1

Small-scale

0.479

High

201431

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

1

Small-scale

0.479

High

1059365

CASP8
Caspase-8

1

1

Small-scale

0.479

High

1317081

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

1

Small-scale

0.479

High

1327694

SHRPN
Sharpin

1

1

Small-scale

0.479

High

868732

ATX1
Ataxin-1

1

0

High-throughput

0.458

High

969982

KIF23
Kinesin-like protein KIF23

1

0

High-throughput

0.458

High

989115

FMR1
Fragile X messenger ribonucleoprotein 1

1

0

High-throughput

0.458

High

1036345

BIRC2
Baculoviral IAP repeat-containing protein 2

1

0

Small-scale

0.458

High

1066672

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1239416

MLKL
Mixed lineage kinase domain-like protein

1

0

Small-scale

0.458

High

1285701

OTUL
Ubiquitin thioesterase otulin

1

0

Small-scale

0.458

High

1290058

RNF31
E3 ubiquitin-protein ligase RNF31

1

0

Small-scale

0.458

High

1292214

AURKB
Aurora kinase B

1

0

High-throughput

0.458

High

1328498

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.458

High

1328499

ECT2
Protein ECT2

1

0

High-throughput

0.458

High

1328500

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

Small-scale

0.458

High

157368

BCKD
Branched-chain alpha-ketoacid dehydrogenase kinase

1

1

High-throughput

0.437

High

1040684

KRR1
KRR1 small subunit processome component homolog

1

0

Small-scale

0.426

High

110688

H3BTL2
Protein-serine/threonine kinase

1

1

High-throughput

0.407

High

1166347

PXDC2
Plexin domain-containing protein 2

1

0

High-throughput

0.301

High

520747

ODBA
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial

1

0

High-throughput

0.279

Low

1318067

RAB34
Ras-related protein Rab-34

1

0

High-throughput

0.269

Low


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Last updated: 15 Jul 2024