Protein: TIA1
Cytotoxic granule associated RNA binding protein TIA1 (Nucleolysin TIA-1 isoform p40) (RNA-binding protein TIA-1) (T-cell-restricted intracellular antigen-1) (TIA-1) (p40-TIA-1)

Gene: TIA1
Organism: Homo sapiens
Interactions: 114
UniProt ID: P31483

Gene Ontology (top 5):
GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
GO:0001818 - negative regulation of cytokine production
GO:0003723 - RNA binding
GO:0003730 - mRNA 3'-UTR binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

680439

TIAR
Nucleolysin TIAR

2

15

Small-scale

0.776

High

680455

ELAV1
ELAV-like protein 1

2

17

Small-scale

0.776

High

446516

SNRPA
U1 small nuclear ribonucleoprotein A

1

19

Small-scale

0.665

High

680422

TIA1
Cytotoxic granule associated RNA binding protein TIA1

1

14

Small-scale

0.665

High

680450

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

17

Small-scale

0.665

High

202596

TXNL1
Thioredoxin-like protein 1

1

2

High-throughput

0.618

High

441896

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

16

Small-scale

0.618

High

680437

SRSF3
Serine/arginine-rich splicing factor 3

1

18

Small-scale

0.618

High

680441

EWS
RNA-binding protein EWS

1

10

High-throughput

0.618

High

680445

G3BP1
Ras GTPase-activating protein-binding protein 1

1

12

High-throughput

0.618

High

680465

RAVR1
Ribonucleoprotein PTB-binding 1

1

14

High-throughput

0.618

High

680490

RC3H2
Roquin-2

1

11

High-throughput

0.618

High

680454

SF01
Splicing factor 1

1

4

High-throughput

0.590

High

496405

TAU
Microtubule-associated protein tau

2

7

Small-scale

0.586

High

320990

PTBP3
Polypyrimidine tract-binding protein 3

1

13

High-throughput

0.575

High

448558

RU1C
U1 small nuclear ribonucleoprotein C

1

2

Small-scale

0.561

High

680452

FASTK
Fas-activated serine/threonine kinase

1

1

Small-scale

0.561

High

680438

CYC
Cytochrome c

2

0

Small-scale

0.559

High

269205

WBP4
WW domain-binding protein 4

1

5

Small-scale

0.541

High

390083

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.536

High

654106

CALX
Calnexin

1

1

High-throughput

0.536

High

680426

KI67
Proliferation marker protein Ki-67

1

8

High-throughput

0.536

High

680429

SOX2
Transcription factor SOX-2

1

3

High-throughput

0.536

High

680446

CUL1
Cullin-1

1

20

High-throughput

0.536

High

680447

CUL2
Cullin-2

1

20

High-throughput

0.536

High

680448

CUL3
Cullin-3

1

20

High-throughput

0.536

High

680449

CUL4A
Cullin-4A

1

20

High-throughput

0.536

High

680463

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

5

High-throughput

0.536

High

680464

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.536

High

680473

CSN5
COP9 signalosome complex subunit 5

1

4

High-throughput

0.536

High

680474

CUL5
Cullin-5

1

20

High-throughput

0.536

High

680478

DCNL1
DCN1-like protein 1

1

3

High-throughput

0.536

High

581473

VCAM1
Vascular cell adhesion protein 1

2

7

High-throughput

0.521

High

680444

ILF3
Interleukin enhancer-binding factor 3

1

10

Small-scale

0.515

High

680435

TM258
Transmembrane protein 258

1

0

High-throughput

0.513

High

680436

DAD1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

1

0

High-throughput

0.513

High

680459

RICTR
Rapamycin-insensitive companion of mTOR

1

0

Small-scale

0.513

High

680475

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.513

High

390731

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.489

High

680428

STT3A
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A

1

1

High-throughput

0.489

High

680469

STT3B
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B

1

1

High-throughput

0.489

High

680484

MAGT1
Magnesium transporter protein 1

1

1

High-throughput

0.489

High

111478

J9JIF5
CXXC-type zinc finger protein 4

1

1

High-throughput

0.479

High

119198

LEG9
Galectin-9

1

2

High-throughput

0.479

High

122516

MEN1
Menin

1

3

High-throughput

0.479

High

130142

ELL2
RNA polymerase II elongation factor ELL2

1

2

High-throughput

0.479

High

226635

PRKN
E3 ubiquitin-protein ligase parkin

1

13

High-throughput

0.479

High

312493

ARI2
E3 ubiquitin-protein ligase ARIH2

1

10

High-throughput

0.479

High

328745

TOP3B
DNA topoisomerase 3-beta-1

1

1

High-throughput

0.479

High

340792

KAD1
Adenylate kinase isoenzyme 1

1

1

High-throughput

0.479

High

346042

MYC
Myc proto-oncogene protein

1

7

High-throughput

0.479

High

369064

ESR1
Estrogen receptor

1

17

Small-scale

0.479

High

379055

MYCN
N-myc proto-oncogene protein

1

7

High-throughput

0.479

High

415223

ATPB
ATP synthase subunit beta, mitochondrial

1

1

Small-scale

0.479

High

452203

HMOX1
Heme oxygenase 1

1

1

Small-scale

0.479

High

528634

CFTR
Cystic fibrosis transmembrane conductance regulator

1

6

Small-scale

0.479

High

589153

ANXA7
Annexin A7

1

1

Small-scale

0.479

High

590604

CD22
B-cell receptor CD22

1

7

Small-scale

0.479

High

659254

DUS1
Dual specificity protein phosphatase 1

1

4

Small-scale

0.479

High

680423

BMI1
Polycomb complex protein BMI-1

1

9

High-throughput

0.479

High

680424

PHB1
Prohibitin 1

1

5

High-throughput

0.479

High

680431

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

5

High-throughput

0.479

High

680432

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

7

High-throughput

0.479

High

680440

OTUD4
OTU domain-containing protein 4

1

5

High-throughput

0.479

High

680442

PO5F1
POU domain, class 5, transcription factor 1

1

1

High-throughput

0.479

High

680453

R3HD1
R3H domain-containing protein 1

1

4

High-throughput

0.479

High

680456

SMN
Survival motor neuron protein

1

1

High-throughput

0.479

High

680458

RBM20
RNA-binding protein 20

1

7

High-throughput

0.479

High

680460

BCOR
BCL-6 corepressor

1

3

High-throughput

0.479

High

680461

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.479

High

680470

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

2

High-throughput

0.479

High

680471

ESR2
Estrogen receptor beta

1

17

High-throughput

0.479

High

680472

RENT1
Regulator of nonsense transcripts 1

1

12

High-throughput

0.479

High

680477

RBM33
RNA-binding protein 33

1

6

High-throughput

0.479

High

680479

FUBP3
Far upstream element-binding protein 3

1

20

High-throughput

0.479

High

680480

PARK7
Parkinson disease protein 7

1

1

Small-scale

0.479

High

680481

TRI31
E3 ubiquitin-protein ligase TRIM31

1

5

High-throughput

0.479

High

680487

TDRD3
Tudor domain-containing protein 3

1

1

High-throughput

0.479

High

680489

NANOG
Homeobox protein NANOG

1

3

High-throughput

0.479

High

680491

ALG13
UDP-N-acetylglucosamine transferase subunit ALG13

1

7

High-throughput

0.479

High

680494

POLK
DNA polymerase kappa

1

1

High-throughput

0.479

High

680495

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

680496

UBQL2
Ubiquilin-2

1

3

High-throughput

0.479

High

680497

DDX20
Probable ATP-dependent RNA helicase DDX20

1

14

High-throughput

0.479

High

680498

KDIS
Kinase D-interacting substrate of 220 kDa

1

1

High-throughput

0.479

High

314845

FMNL1
Formin-like protein 1

1

0

Small-scale

0.458

High

414573

PTMA
Prothymosin alpha [Cleaved into: Prothymosin alpha, N-terminally processed; Thymosin alpha-1]

1

0

Small-scale

0.458

High

680433

GEMI4
Gem-associated protein 4

1

0

High-throughput

0.458

High

680457

MOONR
Protein moonraker

1

0

High-throughput

0.458

High

680462

DPPA4
Developmental pluripotency-associated protein 4

1

0

High-throughput

0.458

High

680476

KCD12
BTB/POZ domain-containing protein KCTD12

1

0

High-throughput

0.458

High

680492

4ET
Eukaryotic translation initiation factor 4E transporter

1

0

High-throughput

0.458

High

305985

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

16

High-throughput

0.445

High

680427

RS9
Small ribosomal subunit protein uS4

1

2

Small-scale

0.445

High

680430

TOB1
Protein Tob1

1

3

Small-scale

0.445

High

680434

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

16

High-throughput

0.445

High

680443

TAGL
Transgelin

1

1

High-throughput

0.445

High

680482

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

16

High-throughput

0.445

High

680483

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

16

High-throughput

0.445

High

680485

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

16

High-throughput

0.445

High

362864

FINC
Fibronectin

1

6

High-throughput

0.437

High

384351

NTRK1
High affinity nerve growth factor receptor

1

4

High-throughput

0.437

High

530453

ITA4
Integrin alpha-4

1

4

High-throughput

0.437

High

680467

NETO2
Neuropilin and tolloid-like protein 2

1

1

High-throughput

0.437

High

680468

TIP
T-cell immunomodulatory protein

1

2

High-throughput

0.437

High

680488

GORS2
Golgi reassembly-stacking protein 2

1

2

High-throughput

0.437

High

371369

ANGI
Angiogenin

1

0

High-throughput

0.426

High

473096

OST4
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4

1

0

High-throughput

0.279

Low

680425

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

0

High-throughput

0.279

Low

680451

MLEC
Malectin

1

0

High-throughput

0.279

Low

680466

KTAP2
Keratinocyte-associated protein 2

1

0

High-throughput

0.279

Low

680493

OSTC
Oligosaccharyltransferase complex subunit OSTC

1

0

High-throughput

0.279

Low

680486

WDCP
WD repeat and coiled-coil-containing protein

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024