Protein: KNL1
Kinetochore scaffold 1 (ALL1-fused gene from chromosome 15q14 protein) (AF15q14) (Bub-linking kinetochore protein) (Blinkin) (Cancer susceptibility candidate gene 5 protein) (Cancer/testis antigen 29) (CT29) (Kinetochore-null protein 1) (Protein CASC5) (Protein D40/AF15q14)

Gene: KNL1
Organism: Homo sapiens
Interactions: 106
UniProt ID: Q8NG31

Gene Ontology (top 5):
GO:0000070 - mitotic sister chromatid segregation
GO:0000776 - kinetochore
GO:0001669 - acrosomal vesicle
GO:0001675 - acrosome assembly
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

211040

BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1

11

1

Small-scale

0.758

High

307996

ZWINT
ZW10 interactor

9

1

Small-scale

0.755

High

1245337

MIS12
Protein MIS12 homolog

8

1

Small-scale

0.750

High

906025

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

6

1

Small-scale

0.737

High

737934

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

6

1

Small-scale

0.735

High

236955

BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

5

1

Small-scale

0.733

High

1240491

SPC24
Kinetochore protein Spc24

6

1

Small-scale

0.732

High

1245327

NSL1
Kinetochore-associated protein NSL1 homolog

7

0

Small-scale

0.720

High

1245339

DSN1
Kinetochore-associated protein DSN1 homolog

8

0

Small-scale

0.720

High

1245343

SPC25
Kinetochore protein Spc25

5

0

Small-scale

0.686

High

155047

NDC80
Kinetochore protein NDC80 homolog

4

0

Small-scale

0.673

High

1245335

NUF2
Kinetochore protein Nuf2

3

0

High-throughput

0.646

High

885581

MLF1
Myeloid leukemia factor 1

3

0

High-throughput

0.638

High

1158376

PMF1
Polyamine-modulated factor 1

3

0

High-throughput

0.638

High

211216

BUB3
Mitotic checkpoint protein BUB3

2

2

High-throughput

0.628

High

744431

ETFB
Electron transfer flavoprotein subunit beta

2

0

High-throughput

0.602

High

1152362

CNDH2
Condensin-2 complex subunit H2

2

0

High-throughput

0.602

High

347378

MYC
Myc proto-oncogene protein

2

0

High-throughput

0.559

High

1245324

BAD
Bcl2-associated agonist of cell death

2

0

High-throughput

0.547

High

708337

TTK
Dual specificity protein kinase TTK

1

0

Small-scale

0.545

High

1024569

CAF1B
Chromatin assembly factor 1 subunit B

1

3

High-throughput

0.536

High

149892

RFXK
DNA-binding protein RFXANK

1

0

High-throughput

0.513

High

323909

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.513

High

382080

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

0

High-throughput

0.513

High

639023

S100P
Protein S100-P

1

0

High-throughput

0.513

High

668839

PML
Protein PML

1

0

High-throughput

0.513

High

714316

HSP74
Heat shock 70 kDa protein 4

1

0

High-throughput

0.513

High

818271

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.513

High

975453

PPARD
Peroxisome proliferator-activated receptor delta

1

0

High-throughput

0.513

High

1050717

FHL2
Four and a half LIM domains protein 2

1

0

High-throughput

0.513

High

1128342

SOLH1
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1

1

0

High-throughput

0.513

High

1132088

SNPC4
snRNA-activating protein complex subunit 4

1

0

High-throughput

0.513

High

1231023

K2C78
Keratin, type II cytoskeletal 78

1

0

High-throughput

0.513

High

1245322

KI18A
Kinesin-like protein KIF18A

1

0

High-throughput

0.513

High

1245328

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.513

High

1245329

DNJC7
DnaJ homolog subfamily C member 7

1

0

High-throughput

0.513

High

1245330

NPAS1
Neuronal PAS domain-containing protein 1

1

0

High-throughput

0.513

High

1245331

NAA11
N-alpha-acetyltransferase 11

1

0

High-throughput

0.513

High

1245334

DUS16
Dual specificity protein phosphatase 16

1

0

High-throughput

0.513

High

1245336

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.513

High

1245340

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.513

High

1245347

HSPB8
Heat shock protein beta-8

1

0

High-throughput

0.513

High

1245348

VPS28
Vacuolar protein sorting-associated protein 28 homolog

1

0

High-throughput

0.513

High

1245352

POLH
DNA polymerase eta

1

0

High-throughput

0.513

High

146640

SOCS2
Suppressor of cytokine signaling 2

1

0

High-throughput

0.493

High

671875

PDIA3
Protein disulfide-isomerase A3

1

0

High-throughput

0.493

High

377509

GCR
Glucocorticoid receptor

1

1

High-throughput

0.479

High

487600

ANDR
Androgen receptor

1

1

High-throughput

0.479

High

553232

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

921652

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

2

High-throughput

0.479

High

980816

TLE3
Transducin-like enhancer protein 3

1

3

High-throughput

0.479

High

1017410

CDC20
Cell division cycle protein 20 homolog

1

3

Small-scale

0.479

High

1026482

RFA4
Replication protein A 30 kDa subunit

1

1

High-throughput

0.479

High

1027139

CBX3
Chromobox protein homolog 3

1

1

High-throughput

0.479

High

1083319

RBBP7
Histone-binding protein RBBP7

1

1

High-throughput

0.479

High

1146637

A16L1
Autophagy-related protein 16-1

1

3

High-throughput

0.479

High

1234353

WDTC1
WD and tetratricopeptide repeats protein 1

1

2

High-throughput

0.479

High

1244385

NUP43
Nucleoporin Nup43

1

3

High-throughput

0.479

High

1245321

COP1
E3 ubiquitin-protein ligase COP1

1

3

High-throughput

0.479

High

1245325

PF21A
PHD finger protein 21A

1

1

High-throughput

0.479

High

1245326

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

3

High-throughput

0.479

High

1245341

SP110
Sp110 nuclear body protein

1

1

High-throughput

0.479

High

1245349

FBW1B
F-box/WD repeat-containing protein 11

1

1

High-throughput

0.479

High

131004

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

0

High-throughput

0.458

High

232344

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.458

High

232937

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

0

High-throughput

0.458

High

387144

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

575793

VINC
Vinculin

1

0

High-throughput

0.458

High

651734

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

720958

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

749695

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.458

High

831506

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.458

High

928638

DYLT1
Dynein light chain Tctex-type 1

1

0

High-throughput

0.458

High

1038549

HDAC1
Histone deacetylase 1

1

0

High-throughput

0.458

High

1056900

MDC1
Mediator of DNA damage checkpoint protein 1

1

0

High-throughput

0.458

High

1134059

DCA12
DDB1- and CUL4-associated factor 12

1

0

High-throughput

0.458

High

1161805

FBX38
F-box only protein 38

1

0

High-throughput

0.458

High

1185063

DET1
DET1 homolog

1

0

High-throughput

0.458

High

1188584

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1200503

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1221583

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1245323

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.458

High

1245332

CENPO
Centromere protein O

1

0

Small-scale

0.458

High

1245338

HIPK2
Homeodomain-interacting protein kinase 2

1

0

High-throughput

0.458

High

1245344

NLE1
Notchless protein homolog 1

1

0

High-throughput

0.458

High

1245345

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

1245346

PURG
Purine-rich element-binding protein gamma

1

0

High-throughput

0.458

High

1245350

RCOR1
REST corepressor 1

1

0

High-throughput

0.458

High

1245353

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

0

High-throughput

0.458

High

111548

K7EJH0
Kinetochore protein Spc24

1

1

High-throughput

0.445

High

316105

CBX6
Chromobox protein homolog 6

1

1

High-throughput

0.445

High

1245333

KTNB1
Katanin p80 WD40 repeat-containing subunit B1

1

2

High-throughput

0.445

High

282970

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

2

High-throughput

0.437

High

1245342

RC3H2
Roquin-2

1

1

High-throughput

0.437

High

718033

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.426

High

1238753

GG6L2
Golgin subfamily A member 6-like protein 2

1

1

High-throughput

0.407

High

645993

CRBB3
Beta-crystallin B3

1

0

High-throughput

0.279

Low

666818

CO4A5

1

0

High-throughput

0.279

Low

823069

AGRE5
Adhesion G protein-coupled receptor E5

1

0

High-throughput

0.279

Low

1101733

CF184
Cilia- and flagella-associated protein 184

1

0

High-throughput

0.279

Low

1139911

BSPRY
B box and SPRY domain-containing protein

1

0

High-throughput

0.279

Low

1238026

PRLD2
PRELI domain-containing protein 2

1

0

High-throughput

0.279

Low

1245351

TMCO1
Calcium load-activated calcium channel

1

0

High-throughput

0.269

Low

1159396

FBX42
F-box only protein 42

1

0

High-throughput

0.249

Low

1238040

CE120
Centrosomal protein of 120 kDa

1

0

High-throughput

0.249

Low

1223607

KATL2
Katanin p60 ATPase-containing subunit A-like 2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024