Protein: T2FB
General transcription factor IIF subunit 2 (General transcription factor IIF 30 kDa subunit) (Transcription initiation factor IIF subunit beta) (TFIIF-beta) (Transcription initiation factor RAP30)

Gene: T2FB, GTF2F2
Organism: Homo sapiens
Interactions: 141
UniProt ID: P13984

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005674 - transcription factor TFIIF complex
GO:0006366 - transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

534072

T2FA
General transcription factor IIF subunit 1

8

2

Small-scale

0.967

High

534069

RPB2
DNA-directed RNA polymerase II subunit RPB2

2

2

High-throughput

0.789

High

534067

T2EB
Transcription initiation factor IIE subunit beta

1

1

Small-scale

0.647

High

243864

BRD4
Bromodomain-containing protein 4

3

2

High-throughput

0.640

High

534056

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

2

2

Small-scale

0.639

High

534089

RPB7
DNA-directed RNA polymerase II subunit RPB7

2

1

High-throughput

0.611

High

534066

T2EA
General transcription factor IIE subunit 1

2

1

Small-scale

0.602

High

534098

TF2B
Transcription initiation factor IIB

2

1

Small-scale

0.602

High

295585

RMP
Unconventional prefoldin RPB5 interactor 1

2

0

Small-scale

0.585

High

534075

BAG6
Large proline-rich protein BAG6

2

0

High-throughput

0.585

High

534144

ANLN
Anillin

2

0

High-throughput

0.585

High

359617

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

2

1

High-throughput

0.584

High

534083

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

2

1

Small-scale

0.584

High

534093

H31
Histone H3.1

2

2

High-throughput

0.584

High

534106

FHL2
Four and a half LIM domains protein 2

2

0

High-throughput

0.580

High

534155

MARE3
Microtubule-associated protein RP/EB family member 3

2

0

High-throughput

0.580

High

534146

CBLN4
Cerebellin-4

2

1

High-throughput

0.574

High

368910

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

534060

RPB1
DNA-directed RNA polymerase II subunit RPB1

2

2

Small-scale

0.571

High

317402

YETS4
YEATS domain-containing protein 4

1

2

Small-scale

0.561

High

534076

RL27A
Large ribosomal subunit protein uL15

1

0

High-throughput

0.554

High

534055

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

3

Small-scale

0.536

High

534084

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

2

High-throughput

0.536

High

534087

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

1

High-throughput

0.536

High

534053

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

Small-scale

0.527

High

534070

OTX2
Homeobox protein OTX2

1

0

High-throughput

0.513

High

534086

APC15
Anaphase-promoting complex subunit 15

1

0

High-throughput

0.513

High

534092

SUMO1
Small ubiquitin-related modifier 1

1

0

High-throughput

0.513

High

534095

SERF2
Small EDRK-rich factor 2

1

0

High-throughput

0.513

High

534102

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

0

High-throughput

0.513

High

534104

NOG2
Nucleolar GTP-binding protein 2

1

0

High-throughput

0.513

High

534114

LBH
Protein LBH

1

0

High-throughput

0.513

High

534129

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.513

High

534139

TCAL7
Transcription elongation factor A protein-like 7

1

0

High-throughput

0.513

High

534079

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.505

High

345299

FOS
Protein c-Fos

1

1

Small-scale

0.501

High

487093

ANDR
Androgen receptor

1

1

Small-scale

0.501

High

534057

TBP
TATA-box-binding protein

1

1

Small-scale

0.501

High

534059

TCEA1
Transcription elongation factor A protein 1

1

3

Small-scale

0.501

High

534062

ARNT
Aryl hydrocarbon receptor nuclear translocator

1

1

Small-scale

0.501

High

534074

AHR
Aryl hydrocarbon receptor

1

1

Small-scale

0.501

High

534123

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.493

High

345819

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.480

High

401340

JUN
Transcription factor Jun

1

0

Small-scale

0.480

High

534054

ATF4
Cyclic AMP-dependent transcription factor ATF-4

1

0

Small-scale

0.480

High

534073

MSX2
Homeobox protein MSX-2

1

0

Small-scale

0.480

High

534105

KLF5
Krueppel-like factor 5

1

0

Small-scale

0.480

High

125129

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

2

High-throughput

0.479

High

178098

IPO8
Importin-8

1

3

High-throughput

0.479

High

212100

HTSF1
17S U2 SnRNP complex component HTATSF1

1

1

Small-scale

0.479

High

331712

NSD2
Histone-lysine N-methyltransferase NSD2

1

1

Small-scale

0.479

High

534061

BRD2
Bromodomain-containing protein 2

1

2

High-throughput

0.479

High

534077

YAP1
Transcriptional coactivator YAP1

1

3

High-throughput

0.479

High

534078

CENPA
Histone H3-like centromeric protein A

1

2

High-throughput

0.479

High

534080

GSK3A
Glycogen synthase kinase-3 alpha

1

1

High-throughput

0.479

High

534081

GSK3B
Glycogen synthase kinase-3 beta

1

1

High-throughput

0.479

High

534082

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

1

High-throughput

0.479

High

534088

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

534096

H33
Histone H3.3

1

2

High-throughput

0.479

High

534099

EWS
RNA-binding protein EWS

1

1

High-throughput

0.479

High

534109

BRD3
Bromodomain-containing protein 3

1

2

High-throughput

0.479

High

534111

TAF5
Transcription initiation factor TFIID subunit 5

1

1

Small-scale

0.479

High

534141

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

1

High-throughput

0.479

High

534156

ASF1A
Histone chaperone ASF1A

1

1

High-throughput

0.479

High

534159

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

1

High-throughput

0.479

High

116659

UBXN8
UBX domain-containing protein 8

1

0

High-throughput

0.458

High

124158

TAF4
Transcription initiation factor TFIID subunit 4

1

0

Small-scale

0.458

High

160353

AURKA
Aurora kinase A

1

0

High-throughput

0.458

High

162378

XPO1
Exportin-1

1

0

High-throughput

0.458

High

179532

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.458

High

302369

CSTN1
Calsyntenin-1

1

0

High-throughput

0.458

High

394041

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.458

High

523488

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.458

High

528461

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.458

High

534052

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

534064

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

534065

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

High-throughput

0.458

High

534068

PML
Protein PML

1

0

High-throughput

0.458

High

534071

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

534085

NP1L1
Nucleosome assembly protein 1-like 1

1

0

High-throughput

0.458

High

534090

H2B1C
Histone H2B type 1-C/E/F/G/I

1

0

High-throughput

0.458

High

534094

RED1
Double-stranded RNA-specific editase 1

1

0

High-throughput

0.458

High

534097

PIPNA
Phosphatidylinositol transfer protein alpha isoform

1

0

High-throughput

0.458

High

534100

TAF10
Transcription initiation factor TFIID subunit 10

1

0

Small-scale

0.458

High

534101

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

0

High-throughput

0.458

High

534107

ZN638
Zinc finger protein 638

1

0

High-throughput

0.458

High

534108

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

534110

STK38
Serine/threonine-protein kinase 38

1

0

High-throughput

0.458

High

534112

MED1
Mediator of RNA polymerase II transcription subunit 1

1

0

Small-scale

0.458

High

534120

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

534121

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

534122

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

534125

RN168
E3 ubiquitin-protein ligase RNF168

1

0

High-throughput

0.458

High

534130

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

534134

FBXW7
F-box/WD repeat-containing protein 7

1

0

High-throughput

0.458

High

534138

CRBN
Protein cereblon

1

0

High-throughput

0.458

High

534140

DDX23
Probable ATP-dependent RNA helicase DDX23

1

0

High-throughput

0.458

High

534143

ESF1
ESF1 homolog

1

0

High-throughput

0.458

High

534147

MED29
Mediator of RNA polymerase II transcription subunit 29

1

0

High-throughput

0.458

High

534150

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

534151

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.458

High

534152

CDC23
Cell division cycle protein 23 homolog

1

0

High-throughput

0.458

High

534153

TASOR
Protein TASOR

1

0

High-throughput

0.458

High

534157

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

534116

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.437

High

534149

HECW2
E3 ubiquitin-protein ligase HECW2

1

2

High-throughput

0.437

High

496205

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

534103

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

0

High-throughput

0.426

High

534128

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.426

High

534117

T184A
Transmembrane protein 184A

2

0

High-throughput

0.328

High

534126

F177A
Protein FAM177A1

2

0

High-throughput

0.318

High

534136

ZMY19
Zinc finger MYND domain-containing protein 19

2

0

High-throughput

0.316

High

534132

DYT2B
Dynein light chain Tctex-type protein 2B

1

0

High-throughput

0.301

High

450637

PAEP
Glycodelin

1

0

High-throughput

0.279

Low

515794

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

0

High-throughput

0.279

Low

534058

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

0

High-throughput

0.279

Low

534063

CO8A1
Collagen alpha-1(VIII) chain

1

0

High-throughput

0.279

Low

534113

GAG2E
G antigen 2E

1

0

High-throughput

0.279

Low

534115

CP141
Cilia- and flagella-associated protein 141

1

0

High-throughput

0.279

Low

534127

CT197
Putative uncharacterized protein encoded by LINC02910

1

0

High-throughput

0.279

Low

534133

JPH3
Junctophilin-3

1

0

High-throughput

0.279

Low

534135

I27L1
Interferon alpha-inducible protein 27-like protein 1

1

0

High-throughput

0.279

Low

534148

PEN2
Gamma-secretase subunit PEN-2

1

0

High-throughput

0.279

Low

534158

ATG4B
Cysteine protease ATG4B

1

0

High-throughput

0.279

Low

534160

SPCS1
Signal peptidase complex subunit 1

1

0

High-throughput

0.279

Low

534161

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

0

High-throughput

0.279

Low

534137

PGAM5
Serine/threonine-protein phosphatase PGAM5, mitochondrial

1

0

High-throughput

0.269

Low

234609

MA1A2
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB

1

0

High-throughput

0.249

Low

316566

ACSL3
Fatty acid CoA ligase Acsl3

1

0

High-throughput

0.249

Low

364517

TRFE
Serotransferrin

1

0

High-throughput

0.249

Low

384196

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

393011

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

0

High-throughput

0.249

Low

453998

COX6C
Cytochrome c oxidase subunit 6C

1

0

High-throughput

0.249

Low

534091

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.249

Low

534118

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

534119

UBP53
Inactive ubiquitin carboxyl-terminal hydrolase 53

1

0

Small-scale

0.249

Low

534124

SHLD1
Shieldin complex subunit 1

1

0

Small-scale

0.249

Low

534142

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

534145

ATG3
Ubiquitin-like-conjugating enzyme ATG3

1

0

High-throughput

0.249

Low

534154

VAV3
Guanine nucleotide exchange factor VAV3

1

0

High-throughput

0.249

Low

534131

ARK74
Aflatoxin B1 aldehyde reductase member 4

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024