Protein: VINC
Vinculin (Metavinculin) (MV)

Gene: VINC, VCL
Organism: Homo sapiens
Interactions: 247
UniProt ID: P18206

Gene Ontology (top 5):
GO:0002009 - morphogenesis of an epithelium
GO:0002162 - dystroglycan binding
GO:0003779 - actin binding
GO:0005198 - structural molecule activity
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

575696

CTNA1
Catenin alpha-1

5

16

Small-scale

0.929

High

575878

TLN1
Talin-1

4

18

Small-scale

0.908

High

575781

RAVR1
Ribonucleoprotein PTB-binding 1

1

2

Small-scale

0.716

High

575706

PAXI
Paxillin

5

17

Small-scale

0.708

High

575687

VINC
Vinculin

1

14

High-throughput

0.698

High

575718

ACTG
Actin, cytoplasmic 2

1

7

High-throughput

0.691

High

521714

CADH1
Cadherin-1

4

20

Small-scale

0.687

High

575712

BCAR1
Breast cancer anti-estrogen resistance protein 1

4

8

Small-scale

0.684

High

575697

CTNB1
Catenin beta-1

4

14

Small-scale

0.678

High

575700

FUS
RNA-binding protein FUS

1

2

High-throughput

0.665

High

575836

SRBS1
Sorbin and SH3 domain-containing protein 1

3

11

Small-scale

0.664

High

575746

TRIP6
Thyroid receptor-interacting protein 6

3

20

High-throughput

0.663

High

238947

LPXN
Leupaxin

3

19

High-throughput

0.661

High

235472

VINEX
Vinexin

3

10

High-throughput

0.653

High

528508

CFTR
Cystic fibrosis transmembrane conductance regulator

3

3

High-throughput

0.650

High

345878

MYC
Myc proto-oncogene protein

3

3

High-throughput

0.640

High

575709

VASP
Vasodilator-stimulated phosphoprotein

3

2

Small-scale

0.640

High

575859

ABI2
Abl interactor 2

2

5

High-throughput

0.632

High

575713

ACTB
Actin, cytoplasmic 1

1

7

High-throughput

0.618

High

575719

ACTC
Actin, alpha cardiac muscle 1

1

7

High-throughput

0.618

High

575724

EWS
RNA-binding protein EWS

1

1

High-throughput

0.618

High

575854

TNR6C
Trinucleotide repeat-containing gene 6C protein

1

4

High-throughput

0.618

High

575702

BRCA1
Breast cancer type 1 susceptibility protein

2

3

High-throughput

0.611

High

282306

NEBL
Nebulette

2

10

High-throughput

0.606

High

575688

VCAM1
Vascular cell adhesion protein 1

2

1

High-throughput

0.601

High

575716

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

2

1

High-throughput

0.601

High

226473

PRKN
E3 ubiquitin-protein ligase parkin

2

4

High-throughput

0.601

High

575749

ENOX2
Ecto-NOX disulfide-thiol exchanger 2

1

0

High-throughput

0.589

High

451360

CLCA
Clathrin light chain A

2

0

High-throughput

0.585

High

575708

GSK3B
Glycogen synthase kinase-3 beta

2

8

High-throughput

0.584

High

575711

TERA
Transitional endoplasmic reticulum ATPase

2

2

High-throughput

0.584

High

575804

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

2

3

High-throughput

0.584

High

575774

SAPC2
Suppressor APC domain-containing protein 2

2

0

High-throughput

0.580

High

575727

CAV1
Caveolin-1

2

5

High-throughput

0.571

High

575738

DAG1
Dystroglycan 1

1

2

Small-scale

0.561

High

575766

TBA1A
Tubulin alpha-1A chain

1

3

Small-scale

0.561

High

241265

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

1

2

High-throughput

0.553

High

575857

BIRC6
Baculoviral IAP repeat-containing protein 6

1

6

High-throughput

0.541

High

561356

LYAM2
E-selectin

1

0

Small-scale

0.537

High

117582

MYO1C
Unconventional myosin-Ic

1

2

High-throughput

0.536

High

164776

SC16A
Protein transport protein Sec16A

1

1

High-throughput

0.536

High

176378

SHIP2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

1

1

High-throughput

0.536

High

280017

MPDZ
Multiple PDZ domain protein

1

7

High-throughput

0.536

High

362795

FINC
Fibronectin

1

2

High-throughput

0.536

High

575737

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

8

High-throughput

0.536

High

575758

RHG17
Rho GTPase-activating protein 17

1

5

High-throughput

0.536

High

575767

HAKAI
E3 ubiquitin-protein ligase Hakai

1

2

Small-scale

0.536

High

575772

TT21B
Tetratricopeptide repeat protein 21B

1

2

High-throughput

0.536

High

575830

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

1

High-throughput

0.536

High

575853

MKNK2
MAP kinase-interacting serine/threonine-protein kinase 2

1

2

High-throughput

0.536

High

575864

RCC2
Protein RCC2

1

1

High-throughput

0.536

High

575868

LIMA1
LIM domain and actin-binding protein 1

1

9

High-throughput

0.536

High

575731

PSME1
Proteasome activator complex subunit 1

1

0

High-throughput

0.518

High

575875

POMP
Proteasome maturation protein

1

0

High-throughput

0.518

High

329336

AGR2
Anterior gradient protein 2 homolog

1

3

High-throughput

0.515

High

575820

OPTN
Optineurin

1

5

High-throughput

0.515

High

575705

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.513

High

575722

HTRA4
Serine protease HTRA4

1

0

High-throughput

0.513

High

575744

L2GL1
Lethal(2) giant larvae protein homolog 1

1

0

High-throughput

0.513

High

575780

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

1

0

High-throughput

0.513

High

575792

PPHLN
Periphilin-1

1

0

High-throughput

0.513

High

575821

CDCA5
Sororin

1

0

High-throughput

0.513

High

575861

HPBP1
Hsp70-binding protein 1

1

0

High-throughput

0.513

High

200161

TGFI1
Transforming growth factor beta-1-induced transcript 1 protein

1

16

Small-scale

0.501

High

298947

SRBS2
Sorbin and SH3 domain-containing protein 2

1

12

Small-scale

0.501

High

443036

ITA5
Integrin alpha-5

1

3

Small-scale

0.501

High

575777

NRAP
Nebulin-related-anchoring protein

1

5

Small-scale

0.501

High

575844

NDEL1
Nuclear distribution protein nudE-like 1

1

1

Small-scale

0.500

High

575733

BRME1
Break repair meiotic recombinase recruitment factor 1

1

1

High-throughput

0.494

High

237874

AP180
Clathrin coat assembly protein AP180

1

1

High-throughput

0.489

High

575751

RBM26
RNA-binding protein 26

1

3

High-throughput

0.489

High

575841

TRI15
E3 ubiquitin-protein ligase TRIM15

1

1

Small-scale

0.481

High

575723

CLH1
Clathrin heavy chain 1

1

0

Small-scale

0.480

High

119149

LEG9
Galectin-9

1

1

High-throughput

0.479

High

154923

NDC80
Kinetochore protein NDC80 homolog

1

4

High-throughput

0.479

High

159880

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

2

High-throughput

0.479

High

160372

AURKA
Aurora kinase A

1

2

High-throughput

0.479

High

236878

BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

1

6

High-throughput

0.479

High

300878

HAUS5
HAUS augmin-like complex subunit 5

1

1

High-throughput

0.479

High

322163

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

2

High-throughput

0.479

High

330847

PAK4
Serine/threonine-protein kinase PAK 4

1

2

High-throughput

0.479

High

384232

NTRK1
High affinity nerve growth factor receptor

1

13

High-throughput

0.479

High

413823

GELS
Gelsolin

1

1

Small-scale

0.479

High

503403

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.479

High

507841

FGFR1
Fibroblast growth factor receptor 1

1

14

High-throughput

0.479

High

530412

ITA4
Integrin alpha-4

1

3

High-throughput

0.479

High

551907

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.479

High

575689

FGFR4
Fibroblast growth factor receptor 4

1

14

High-throughput

0.479

High

575690

CDK2
Cyclin-dependent kinase 2

1

3

High-throughput

0.479

High

575691

MOES
Moesin

1

6

High-throughput

0.479

High

575694

CADH5
Cadherin-5

1

20

Small-scale

0.479

High

575695

TTK
Dual specificity protein kinase TTK

1

2

High-throughput

0.479

High

575701

VGFR2
Vascular endothelial growth factor receptor 2

1

5

Small-scale

0.479

High

575703

CCNF
Cyclin-F

1

1

High-throughput

0.479

High

575704

YAP1
Transcriptional coactivator YAP1

1

7

High-throughput

0.479

High

575707

GSK3A
Glycogen synthase kinase-3 alpha

1

8

High-throughput

0.479

High

575710

KIF11
Kinesin-like protein KIF11

1

2

High-throughput

0.479

High

575714

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

2

High-throughput

0.479

High

575717

1433Z
14-3-3 protein zeta/delta

1

5

High-throughput

0.479

High

575725

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

3

High-throughput

0.479

High

575726

DYST
Dystonin

1

13

High-throughput

0.479

High

575728

RON
Macrophage-stimulating protein receptor

1

16

High-throughput

0.479

High

575729

PTN12
Tyrosine-protein phosphatase non-receptor type 12

1

1

High-throughput

0.479

High

575732

ZO1
Tight junction protein ZO-1

1

9

High-throughput

0.479

High

575734

FOXO1
Forkhead box protein O1

1

2

High-throughput

0.479

High

575735

BIRC3
Baculoviral IAP repeat-containing protein 3

1

5

High-throughput

0.479

High

575736

CUL4A
Cullin-4A

1

1

High-throughput

0.479

High

575740

TRI14
Tripartite motif-containing protein 14

1

2

High-throughput

0.479

High

575743

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.479

High

575748

ZYX
Zyxin

1

20

High-throughput

0.479

High

575750

DUS28
Dual specificity phosphatase 28

1

3

High-throughput

0.479

High

575760

EDC4
Enhancer of mRNA-decapping protein 4

1

3

High-throughput

0.479

High

575761

CEP85
Centrosomal protein of 85 kDa

1

5

High-throughput

0.479

High

575763

DNMBP
Dynamin-binding protein

1

6

High-throughput

0.479

High

575764

TRI67
Tripartite motif-containing protein 67

1

9

High-throughput

0.479

High

575765

MOB3C
MOB kinase activator 3C

1

3

High-throughput

0.479

High

575770

ZFY16
Zinc finger FYVE domain-containing protein 16

1

3

High-throughput

0.479

High

575776

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

575778

GOLI
E3 ubiquitin-protein ligase RNF130

1

1

High-throughput

0.479

High

575779

CEP97
Centrosomal protein of 97 kDa

1

3

High-throughput

0.479

High

575782

DCP1B
mRNA-decapping enzyme 1B

1

2

High-throughput

0.479

High

575783

RHG24
Rho GTPase-activating protein 24

1

6

High-throughput

0.479

High

575785

ENAH
Protein enabled homolog

1

5

High-throughput

0.479

High

575786

NHLC2
NHL repeat-containing protein 2

1

1

High-throughput

0.479

High

575789

RN149
E3 ubiquitin-protein ligase RNF149

1

2

High-throughput

0.479

High

575791

NAV1
Neuron navigator 1

1

3

High-throughput

0.479

High

575798

CIP2A
Protein CIP2A

1

1

High-throughput

0.479

High

575799

ALMS1
Centrosome-associated protein ALMS1

1

2

High-throughput

0.479

High

575800

BICD2
Protein bicaudal D homolog 2

1

5

High-throughput

0.479

High

575801

FBF1
Fas-binding factor 1

1

4

High-throughput

0.479

High

575806

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

High-throughput

0.479

High

575809

HDAC2
Histone deacetylase 2

1

2

High-throughput

0.479

High

575811

LPP
Lipoma-preferred partner

1

20

High-throughput

0.479

High

575813

MRTFA
Myocardin-related transcription factor A

1

7

High-throughput

0.479

High

575815

ARMC5
Armadillo repeat-containing protein 5

1

7

High-throughput

0.479

High

575817

CHM4C
Charged multivesicular body protein 4c

1

1

High-throughput

0.479

High

575824

CLMN
Calmin

1

9

High-throughput

0.479

High

575827

PASK
PAS domain-containing serine/threonine-protein kinase

1

3

High-throughput

0.479

High

575828

RUFY1
RUN and FYVE domain-containing protein 1

1

3

High-throughput

0.479

High

575831

SH3G1
Endophilin-A2

1

9

High-throughput

0.479

High

575835

LRC61
Leucine-rich repeat-containing protein 61

1

1

High-throughput

0.479

High

575837

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

3

High-throughput

0.479

High

575842

TB182
182 kDa tankyrase-1-binding protein

1

3

High-throughput

0.479

High

575846

SLK
STE20-like serine/threonine-protein kinase

1

6

High-throughput

0.479

High

575847

PTN23
Tyrosine-protein phosphatase non-receptor type 23

1

1

High-throughput

0.479

High

575848

WNK1
Serine/threonine-protein kinase WNK1

1

5

High-throughput

0.479

High

575849

ASB7
Ankyrin repeat and SOCS box protein 7

1

6

High-throughput

0.479

High

575850

PEAK1
Inactive tyrosine-protein kinase PEAK1

1

6

High-throughput

0.479

High

575851

PKHA5
Pleckstrin homology domain-containing family A member 5

1

10

High-throughput

0.479

High

575856

E41L5
Band 4.1-like protein 5

1

5

High-throughput

0.479

High

575858

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

5

High-throughput

0.479

High

575860

GGA3
ADP-ribosylation factor-binding protein GGA3

1

1

High-throughput

0.479

High

575862

PD1L1
Programmed cell death 1 ligand 1

1

2

High-throughput

0.479

High

575865

SI1L2
Signal-induced proliferation-associated 1-like protein 2

1

3

High-throughput

0.479

High

575866

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

575867

LIMD1
LIM domain-containing protein 1

1

20

High-throughput

0.479

High

575869

TBK1
Serine/threonine-protein kinase TBK1

1

8

High-throughput

0.479

High

575870

KDIS
Kinase D-interacting substrate of 220 kDa

1

4

High-throughput

0.479

High

575872

MACF1
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5

1

13

High-throughput

0.479

High

575874

COR2B
Coronin-2B

1

2

Small-scale

0.479

High

558979

H15
Histone H1.5

1

1

High-throughput

0.470

High

263511

PR40A
Pre-mRNA-processing factor 40 homolog A

1

6

High-throughput

0.464

High

168882

ARPC2
Actin-related protein 2/3 complex subunit 2

1

0

Small-scale

0.458

High

200492

CP110
Centriolar coiled-coil protein of 110 kDa

1

0

High-throughput

0.458

High

203209

SYNJ1
Synaptojanin-1

1

0

High-throughput

0.458

High

209656

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

243287

DNJA2
DnaJ homolog subfamily A member 2

1

0

High-throughput

0.458

High

430046

PROF1
Profilin-1

1

0

High-throughput

0.458

High

562503

IL7RA
Interleukin-7 receptor subunit alpha

1

0

High-throughput

0.458

High

575699

GDE
Glycogen debranching enzyme

1

0

High-throughput

0.458

High

575715

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.458

High

575741

DPYL1
Dihydropyrimidinase-related protein 1

1

0

High-throughput

0.458

High

575754

FOCAD
Focadhesin

1

0

Small-scale

0.458

High

575756

HAUS3
HAUS augmin-like complex subunit 3

1

0

High-throughput

0.458

High

575757

CRBG3
Very large A-kinase anchor protein

1

0

High-throughput

0.458

High

575768

CCD80
Coiled-coil domain-containing protein 80

1

0

High-throughput

0.458

High

575771

CLAP1
CLIP-associating protein 1

1

0

High-throughput

0.458

High

575773

SLN11
Schlafen family member 11

1

0

High-throughput

0.458

High

575775

N4BP2
NEDD4-binding protein 2

1

0

High-throughput

0.458

High

575784

ARFG2
ADP-ribosylation factor GTPase-activating protein 2

1

0

High-throughput

0.458

High

575788

SPC24
Kinetochore protein Spc24

1

0

High-throughput

0.458

High

575793

KNL1
Kinetochore scaffold 1

1

0

High-throughput

0.458

High

575797

FBX30
F-box only protein 30

1

0

High-throughput

0.458

High

575802

SMCR8
Guanine nucleotide exchange protein SMCR8

1

0

High-throughput

0.458

High

575814

SKA1
Spindle and kinetochore-associated protein 1

1

0

High-throughput

0.458

High

575818

HAUS1
HAUS augmin-like complex subunit 1

1

0

High-throughput

0.458

High

575825

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

575829

NUP88
Nuclear pore complex protein Nup88

1

0

High-throughput

0.458

High

575834

HAUS8
HAUS augmin-like complex subunit 8

1

0

High-throughput

0.458

High

575855

Q9HCK3
KIAA1569 protein

1

0

High-throughput

0.458

High

575881

NUBP2
Cytosolic Fe-S cluster assembly factor NUBP2

1

0

High-throughput

0.458

High

575863

VSX1
Visual system homeobox 1

1

2

High-throughput

0.457

High

270569

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

4

High-throughput

0.445

High

472673

FBSP1
F-box/SPRY domain-containing protein 1

1

11

High-throughput

0.445

High

496259

TAU
Microtubule-associated protein tau

1

7

High-throughput

0.445

High

575720

UBX2A
UBX domain-containing protein 2A

1

3

High-throughput

0.445

High

575721

RAE1L
mRNA export factor RAE1

1

2

High-throughput

0.445

High

575739

UBE4A
Ubiquitin conjugation factor E4 A

1

1

High-throughput

0.445

High

575742

UBX2B
UBX domain-containing protein 2B

1

3

High-throughput

0.445

High

575745

PP1R7
Protein phosphatase 1 regulatory subunit 7

1

5

High-throughput

0.445

High

575753

CE350
Centrosome-associated protein 350

1

2

High-throughput

0.445

High

575759

PKHA7
Pleckstrin homology domain-containing family A member 7

1

10

High-throughput

0.445

High

575762

CSAG1
Chondrosarcoma-associated gene 1 protein

1

1

High-throughput

0.445

High

575807

UBXN4
UBX domain-containing protein 4

1

4

High-throughput

0.445

High

575819

FAF2
FAS-associated factor 2

1

2

High-throughput

0.445

High

575839

ASPC1
Tether containing UBX domain for GLUT4

1

1

High-throughput

0.445

High

575840

UBXN6
UBX domain-containing protein 6

1

1

High-throughput

0.445

High

575871

NSF1C
NSFL1 cofactor p47

1

3

High-throughput

0.445

High

575876

PLAP
Phospholipase A-2-activating protein

1

5

High-throughput

0.445

High

416929

IF4E
Eukaryotic translation initiation factor 4E

1

0

High-throughput

0.438

High

575692

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.437

High

575698

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

575747

EZH2
Histone-lysine N-methyltransferase EZH2

1

3

High-throughput

0.437

High

575755

DCA15
DDB1- and CUL4-associated factor 15

1

1

High-throughput

0.437

High

575769

KCTD9
BTB/POZ domain-containing protein KCTD9

1

1

High-throughput

0.437

High

575803

PHIP
PH-interacting protein

1

2

Small-scale

0.437

High

575808

ESR2
Estrogen receptor beta

1

8

High-throughput

0.437

High

575838

K1671
Uncharacterized protein KIAA1671

1

1

High-throughput

0.437

High

575843

TANC1
Protein TANC1

1

5

High-throughput

0.437

High

575852

RC3H2
Roquin-2

1

4

High-throughput

0.437

High

575873

TRI33
E3 ubiquitin-protein ligase TRIM33

1

2

High-throughput

0.437

High

266104

ERLN1
Erlin-1

1

0

High-throughput

0.426

High

575693

METK2
S-adenosylmethionine synthase isoform type-2

1

0

High-throughput

0.426

High

575794

SVIP
Small VCP/p97-interacting protein

1

0

High-throughput

0.426

High

575796

NPL4
Nuclear protein localization protein 4 homolog

1

0

High-throughput

0.426

High

575805

IP6K1
Inositol hexakisphosphate kinase 1

1

0

High-throughput

0.426

High

575810

UFD1
Ubiquitin recognition factor in ER-associated degradation protein 1

1

0

High-throughput

0.426

High

575822

NGLY1
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase

1

0

High-throughput

0.426

High

575823

VCIP1
Deubiquitinating protein VCPIP1

1

0

High-throughput

0.426

High

575826

RILP
Rab-interacting lysosomal protein

1

0

Small-scale

0.426

High

575832

SELS
Selenoprotein S

1

0

High-throughput

0.426

High

575882

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

0

High-throughput

0.426

High

116661

UBXN8
UBX domain-containing protein 8

1

2

High-throughput

0.407

High

575790

SPRY3
SPRY domain-containing protein 3

1

2

High-throughput

0.407

High

575880

CSAG2
Chondrosarcoma-associated gene 2/3 protein

1

1

High-throughput

0.407

High

575812

TEKT1
Tektin-1

1

0

High-throughput

0.299

High

575752

GKAP1
G kinase-anchoring protein 1

1

0

High-throughput

0.279

Low

575845

ASCC2
Activating signal cointegrator 1 complex subunit 2

1

0

High-throughput

0.279

Low

575877

AP3M1
AP-3 complex subunit mu-1

1

0

High-throughput

0.279

Low

575730

P2R3A
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha

1

0

High-throughput

0.249

Low

575795

THOC2
THO complex subunit 2

1

0

High-throughput

0.249

Low

575833

PHAF1
Phagosome assembly factor 1

1

0

High-throughput

0.249

Low

575879

LOXL2
Lysyl oxidase homolog 2

1

0

High-throughput

0.249

Low

123360

GET1
Guided entry of tail-anchored proteins factor 1

1

0

High-throughput

0.232

Low

575787

UBAC2
Ubiquitin-associated domain-containing protein 2

1

0

High-throughput

0.232

Low

575816

P5CR2
Pyrroline-5-carboxylate reductase 2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024