Protein: KIF2C
Kinesin-like protein KIF2C (Kinesin-like protein 6) (Mitotic centromere-associated kinesin) (MCAK)

Gene: KIF2C
Organism: Homo sapiens
Interactions: 166
UniProt ID: Q99661

Gene Ontology (top 5):
GO:0000775 - chromosome, centromeric region
GO:0000776 - kinetochore
GO:0003777 - microtubule motor activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

116899

KIF2A
Kinesin-like protein KIF2A

2

18

High-throughput

0.811

High

1233708

KIF2B
Kinesin-like protein KIF2B

2

17

High-throughput

0.811

High

1077095

MARE1
Microtubule-associated protein RP/EB family member 1

9

15

Small-scale

0.754

High

1305465

KIF2C
Kinesin-like protein KIF2C

1

13

Small-scale

0.713

High

1305492

DYN3
Dynamin-3

3

3

High-throughput

0.667

High

584459

TNR1A
Tumor necrosis factor receptor superfamily member 1A

2

5

High-throughput

0.628

High

1255364

TCP1L
T-complex protein 10A homolog 1

2

1

High-throughput

0.628

High

1127136

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

12

Small-scale

0.622

High

1066578

KIF14
Kinesin-like protein KIF14

1

18

High-throughput

0.618

High

1205419

KI18B
Kinesin-like protein KIF18B

1

18

High-throughput

0.618

High

1131824

CE170
Centrosomal protein of 170 kDa

2

16

High-throughput

0.611

High

395566

A4
Amyloid-beta precursor protein

2

11

High-throughput

0.602

High

1037089

MED21
Mediator of RNA polymerase II transcription subunit 21

2

0

High-throughput

0.602

High

1293226

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.602

High

347695

MYC
Myc proto-oncogene protein

2

8

High-throughput

0.584

High

1051430

DCTN1
Dynactin subunit 1

2

14

High-throughput

0.584

High

1305491

MARE3
Microtubule-associated protein RP/EB family member 3

2

15

High-throughput

0.584

High

313981

PPN
Papilin

2

5

High-throughput

0.574

High

1103168

KLH40
Kelch-like protein 40

2

3

High-throughput

0.574

High

1153142

TYW3
tRNA wybutosine-synthesizing protein 3 homolog

2

2

High-throughput

0.574

High

370284

ESR1
Estrogen receptor

2

18

High-throughput

0.571

High

861907

PLK1
Serine/threonine-protein kinase PLK1

1

13

Small-scale

0.561

High

1173218

PAXI1
PAX-interacting protein 1

1

5

High-throughput

0.552

High

1282572

ZN566
Zinc finger protein 566

1

4

High-throughput

0.541

High

200230

SRGP3
SLIT-ROBO Rho GTPase-activating protein 3

1

5

High-throughput

0.536

High

201974

WDR62
WD repeat-containing protein 62

1

7

High-throughput

0.536

High

281047

KRT38
Keratin, type I cuticular Ha8

1

16

High-throughput

0.536

High

381026

SEMG1
Semenogelin-1

1

1

High-throughput

0.536

High

422563

CENPB
Major centromere autoantigen B

1

1

High-throughput

0.536

High

575154

RL7
Large ribosomal subunit protein uL30

1

2

High-throughput

0.536

High

580683

ML12A
Myosin regulatory light chain 12A

1

10

High-throughput

0.536

High

586939

CSK22
Casein kinase II subunit alpha'

1

5

High-throughput

0.536

High

591395

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

7

High-throughput

0.536

High

654043

MAP4
Microtubule-associated protein 4

1

14

High-throughput

0.536

High

675219

CLIP1
CAP-Gly domain-containing linker protein 1

1

12

High-throughput

0.536

High

702139

RL9
Large ribosomal subunit protein uL6

1

2

High-throughput

0.536

High

796164

MAGA9
Melanoma-associated antigen 9

1

7

High-throughput

0.536

High

806134

RL5
Large ribosomal subunit protein uL18

1

1

High-throughput

0.536

High

821015

PRC2A
Protein PRRC2A

1

12

High-throughput

0.536

High

827266

ARRB1
Beta-arrestin-1

1

2

High-throughput

0.536

High

846576

DUS3
Dual specificity protein phosphatase 3

1

5

High-throughput

0.536

High

876717

BRPF1
Peregrin

1

5

High-throughput

0.536

High

970640

SEMG2
Semenogelin-2

1

1

High-throughput

0.536

High

990919

ZO1
Tight junction protein ZO-1

1

16

High-throughput

0.536

High

1023097

STK4
Serine/threonine-protein kinase 4

1

19

High-throughput

0.536

High

1026644

FADD
FAS-associated death domain protein

1

2

High-throughput

0.536

High

1027419

STK3
Serine/threonine-protein kinase 3

1

17

High-throughput

0.536

High

1039798

SNW1
SNW domain-containing protein 1

1

4

High-throughput

0.536

High

1121622

BOREA
Borealin

1

1

High-throughput

0.536

High

1127893

RRP12
RRP12-like protein

1

2

High-throughput

0.536

High

1128522

HABP4
Intracellular hyaluronan-binding protein 4

1

3

High-throughput

0.536

High

1135215

RBM26
RNA-binding protein 26

1

4

High-throughput

0.536

High

1140446

K2C79
Keratin, type II cytoskeletal 79

1

10

High-throughput

0.536

High

1190184

CLAP1
CLIP-associating protein 1

1

3

High-throughput

0.536

High

1197584

PCGF5
Polycomb group RING finger protein 5

1

9

High-throughput

0.536

High

1242113

LS14A
Protein LSM14 homolog A

1

5

High-throughput

0.536

High

1268079

MY18A
Unconventional myosin-XVIIIa

1

9

High-throughput

0.536

High

1271747

TANK
TRAF family member-associated NF-kappa-B activator

1

2

High-throughput

0.536

High

1295828

ZN668
Zinc finger protein 668

1

2

High-throughput

0.536

High

1303686

CDC5L
Cell division cycle 5-like protein

1

5

High-throughput

0.536

High

1305468

CAB45
45 kDa calcium-binding protein

1

9

High-throughput

0.536

High

1305483

TBCD7
TBC1 domain family member 7

1

1

High-throughput

0.536

High

1305484

ARP3B
Actin-related protein 3B

1

5

High-throughput

0.536

High

1305487

MBD1
Methyl-CpG-binding domain protein 1

1

4

High-throughput

0.536

High

1305493

RBMX2
RNA-binding motif protein, X-linked 2

1

9

High-throughput

0.536

High

1305496

SAR1B
Small COPII coat GTPase SAR1B

1

6

High-throughput

0.536

High

648070

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

1

0

High-throughput

0.513

High

722634

T2FA
General transcription factor IIF subunit 1

1

0

High-throughput

0.513

High

920539

RS25
Small ribosomal subunit protein eS25

1

0

High-throughput

0.513

High

986978

SUH
Recombining binding protein suppressor of hairless

1

0

High-throughput

0.513

High

1056810

ESPL1
Separin

1

0

High-throughput

0.513

High

1125681

SGO1
Shugoshin 1

1

0

High-throughput

0.513

High

1204456

FBX11
F-box only protein 11

1

0

High-throughput

0.513

High

1237065

HORM2
HORMA domain-containing protein 2

1

0

High-throughput

0.513

High

1243247

DDHD1
Phospholipase DDHD1

1

0

High-throughput

0.513

High

1261486

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

1

0

High-throughput

0.513

High

1305472

S6A15
Sodium-dependent neutral amino acid transporter B(0)AT2

1

0

High-throughput

0.513

High

1305476

PAAT
ATPase PAAT

1

0

High-throughput

0.513

High

1305481

TEX10
Testis-expressed protein 10

1

0

High-throughput

0.513

High

1305485

BCCIP
BRCA2 and CDKN1A-interacting protein

1

0

High-throughput

0.513

High

1305489

FBX5
F-box only protein 5

1

0

High-throughput

0.513

High

772126

VHL
von Hippel-Lindau disease tumor suppressor

1

4

Small-scale

0.508

High

931814

CSK2B
Casein kinase II subunit beta

1

1

High-throughput

0.508

High

160733

AURKA
Aurora kinase A

1

7

Small-scale

0.501

High

902733

SUMO2
Small ubiquitin-related modifier 2

1

5

High-throughput

0.501

High

307273

RCBT2
RCC1 and BTB domain-containing protein 2

1

7

High-throughput

0.489

High

648589

CALL3
Calmodulin-like protein 3

1

7

High-throughput

0.489

High

678053

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

1

High-throughput

0.489

High

1034722

ADAM9
Disintegrin and metalloproteinase domain-containing protein 9

1

3

High-throughput

0.489

High

1102629

INSY1
Inhibitory synaptic factor 1

1

3

High-throughput

0.489

High

1138140

PR38B
Pre-mRNA-splicing factor 38B

1

3

High-throughput

0.489

High

1173310

ANKS3
Ankyrin repeat and SAM domain-containing protein 3

1

14

High-throughput

0.489

High

1289239

RMXL1
RNA binding motif protein, X-linked-like-1

1

9

High-throughput

0.489

High

1293850

MR1L1
MORF4 family-associated protein 1-like 1

1

3

High-throughput

0.489

High

1305469

WDR18
WD repeat-containing protein 18

1

7

High-throughput

0.489

High

1305471

NDEL1
Nuclear distribution protein nudE-like 1

1

15

High-throughput

0.481

High

1305473

CENPH
Centromere protein H

1

0

Small-scale

0.480

High

125669

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

9

High-throughput

0.479

High

149211

CTRO
Citron Rho-interacting kinase

1

5

High-throughput

0.479

High

151158

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

16

High-throughput

0.479

High

228472

PRKN
E3 ubiquitin-protein ligase parkin

1

10

High-throughput

0.479

High

244841

BRD4
Bromodomain-containing protein 4

1

10

High-throughput

0.479

High

385410

NTRK1
High affinity nerve growth factor receptor

1

15

High-throughput

0.479

High

504632

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.479

High

538006

KPYM
Pyruvate kinase PKM

1

2

Small-scale

0.479

High

553527

RFA2
Replication protein A 32 kDa subunit

1

9

High-throughput

0.479

High

570000

CEBPB
CCAAT/enhancer-binding protein beta

1

8

High-throughput

0.479

High

575553

EGR1
Early growth response protein 1

1

6

High-throughput

0.479

High

640268

PTN3
Tyrosine-protein phosphatase non-receptor type 3

1

10

High-throughput

0.479

High

652059

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

8

High-throughput

0.479

High

656298

PSA5
Proteasome subunit alpha type-5

1

3

Small-scale

0.479

High

749813

BRCA1
Breast cancer type 1 susceptibility protein

1

14

High-throughput

0.479

High

779977

CCNF
Cyclin-F

1

6

High-throughput

0.479

High

882518

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

11

High-throughput

0.479

High

894797

RAB8A
Ras-related protein Rab-8A

1

3

Small-scale

0.479

High

905033

1433G
14-3-3 protein gamma

1

20

High-throughput

0.479

High

917807

H4
Histone H4

1

5

High-throughput

0.479

High

918637

H2B1C
Histone H2B type 1-C/E/F/G/I

1

17

High-throughput

0.479

High

935162

H31
Histone H3.1

1

20

High-throughput

0.479

High

961251

HSF1
Heat shock factor protein 1

1

1

High-throughput

0.479

High

982421

1433F
14-3-3 protein eta

1

20

High-throughput

0.479

High

1035278

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

4

High-throughput

0.479

High

1042370

CUL3
Cullin-3

1

9

High-throughput

0.479

High

1064066

TNIP1
TNFAIP3-interacting protein 1

1

18

High-throughput

0.479

High

1188773

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

6

High-throughput

0.479

High

1222538

SLX4
Structure-specific endonuclease subunit SLX4

1

10

High-throughput

0.479

High

1243902

FBX22
F-box only protein 22

1

3

High-throughput

0.479

High

1269447

ESR2
Estrogen receptor beta

1

16

High-throughput

0.479

High

1292182

AURKB
Aurora kinase B

1

7

Small-scale

0.479

High

1303139

RMD3
Regulator of microtubule dynamics protein 3

1

2

High-throughput

0.479

High

1305466

ANM1
Protein arginine N-methyltransferase 1

1

3

High-throughput

0.479

High

1305470

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

5

High-throughput

0.479

High

1305475

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.479

High

1305478

TRI36
E3 ubiquitin-protein ligase TRIM36

1

20

High-throughput

0.479

High

1305479

ANLN
Anillin

1

7

High-throughput

0.479

High

1305480

BIRC6
Baculoviral IAP repeat-containing protein 6

1

7

Small-scale

0.479

High

1305486

ZRAN1
Ubiquitin thioesterase ZRANB1

1

18

High-throughput

0.479

High

1305488

APC4
Anaphase-promoting complex subunit 4

1

3

Small-scale

0.479

High

1305495

TRAF6
TNF receptor-associated factor 6

1

20

Small-scale

0.479

High

1204322

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.458

High

1283252

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.458

High

1305477

ZN287
Zinc finger protein 287

1

1

High-throughput

0.445

High

205883

TGON2
Trans-Golgi network integral membrane protein 2

1

10

High-throughput

0.437

High

363273

FINC
Fibronectin

1

2

High-throughput

0.437

High

721253

RFA3
Replication protein A 14 kDa subunit

1

7

High-throughput

0.437

High

824307

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

3

High-throughput

0.437

High

1171394

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.437

High

1231317

RHG24
Rho GTPase-activating protein 24

1

6

High-throughput

0.437

High

1305474

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.437

High

1305490

HECD1
E3 ubiquitin-protein ligase HECTD1

1

16

High-throughput

0.437

High

1122401

SGO2
Shugoshin 2

1

0

Small-scale

0.426

High

1305482

GRHL1
Grainyhead-like protein 1 homolog

1

0

High-throughput

0.426

High

831627

CEBPA
CCAAT/enhancer-binding protein alpha

1

8

High-throughput

0.408

High

1086289

H31T
Histone H3.1t

1

20

Small-scale

0.408

High

581835

VCAM1
Vascular cell adhesion protein 1

1

5

High-throughput

0.407

High

1290288

SGF29
SAGA-associated factor 29

3

0

High-throughput

0.347

High

528129

BMP1
Bone morphogenetic protein 1

2

0

High-throughput

0.328

High

1240666

RELL2
RELT-like protein 2

2

0

High-throughput

0.328

High

1198765

RM52
Large ribosomal subunit protein mL52

1

0

High-throughput

0.279

Low

1245974

SMS2
Phosphatidylcholine:ceramide cholinephosphotransferase 2

1

0

High-throughput

0.279

Low

1290339

RRP36
Ribosomal RNA processing protein 36 homolog

1

0

High-throughput

0.279

Low

1304626

POP1
Ribonucleases P/MRP protein subunit POP1

1

0

High-throughput

0.279

Low

1305467

KXDL1
KxDL motif-containing protein 1

1

0

High-throughput

0.279

Low

1305494

UTP11
Probable U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.279

Low

118416

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024