Protein: MCR
Mineralocorticoid receptor (MR) (Nuclear receptor subfamily 3 group C member 2)

Gene: MCR, NR3C2
Organism: Homo sapiens
Interactions: 37
UniProt ID: P08235

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
GO:0003707 - nuclear steroid receptor activity
GO:0004879 - nuclear receptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

377021

GCR
Glucocorticoid receptor

2

20

Small-scale

0.783

High

437642

NCOA1
Nuclear receptor coactivator 1

2

20

Small-scale

0.757

High

437644

CARME
Carnosine N-methyltransferase

3

1

High-throughput

0.667

High

170218

TIF1A
Transcription intermediary factor 1-alpha

3

20

Small-scale

0.651

High

437656

FAF1
FAS-associated factor 1

2

8

Small-scale

0.649

High

437626

RXRA
Retinoic acid receptor RXR-alpha

1

20

High-throughput

0.621

High

437652

DAXX
Death domain-associated protein 6

1

4

Small-scale

0.552

High

437643

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

9

High-throughput

0.536

High

437639

EP300
Histone acetyltransferase p300

1

20

Small-scale

0.515

High

437651

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.513

High

437653

PRAF1
Prenylated Rab acceptor protein 1

1

2

High-throughput

0.494

High

437627

ACSL1
Long-chain-fatty-acid--CoA ligase 1

1

6

High-throughput

0.481

High

437631

PRS8
26S proteasome regulatory subunit 8

1

20

High-throughput

0.481

High

437632

SUMO1
Small ubiquitin-related modifier 1

1

15

Small-scale

0.481

High

437633

UBC9
SUMO-conjugating enzyme UBC9

1

13

Small-scale

0.481

High

437645

PROX1
Prospero homeobox protein 1

1

3

High-throughput

0.481

High

437654

C8AP2
CASP8-associated protein 2

1

1

Small-scale

0.481

High

116957

SGK1
Serine/threonine-protein kinase Sgk1

1

17

Small-scale

0.479

High

118677

AIP
AH receptor-interacting protein

1

20

Small-scale

0.479

High

431441

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.479

High

437625

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.479

High

437628

NRIP1
Nuclear receptor-interacting protein 1

1

19

Small-scale

0.479

High

437629

PPP5
Serine/threonine-protein phosphatase 5

1

20

Small-scale

0.479

High

437630

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

14

Small-scale

0.479

High

437634

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

20

Small-scale

0.479

High

437635

CAV1
Caveolin-1

1

5

Small-scale

0.479

High

437636

1433F
14-3-3 protein eta

1

20

High-throughput

0.479

High

437637

UBE3A
Ubiquitin-protein ligase E3A

1

20

Small-scale

0.479

High

437638

PPID
Peptidyl-prolyl cis-trans isomerase D

1

8

Small-scale

0.479

High

437640

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

20

Small-scale

0.479

High

437641

TEBP
Prostaglandin E synthase 3

1

8

Small-scale

0.479

High

437646

CBP
CREB-binding protein

1

20

Small-scale

0.479

High

437647

KAT2A
Histone acetyltransferase KAT2A

1

20

Small-scale

0.479

High

437648

KAT2B
Histone acetyltransferase KAT2B

1

20

Small-scale

0.479

High

437649

T22D3
TSC22 domain family protein 3

1

1

Small-scale

0.479

High

437650

DNJC7
DnaJ homolog subfamily C member 7

1

20

Small-scale

0.479

High

437655

CHIP
E3 ubiquitin-protein ligase CHIP

1

20

Small-scale

0.479

High


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Last updated: 15 Jul 2024