Protein: WNK4
Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase lysine-deficient 4) (Protein kinase with no lysine 4)

Gene: WNK4
Organism: Homo sapiens
Interactions: 22
UniProt ID: Q96J92

Gene Ontology (top 5):
GO:0002021 - response to dietary excess
GO:0003096 - renal sodium ion transport
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

320562

OXSR1
Serine/threonine-protein kinase OSR1

2

19

Small-scale

0.799

High

1294943

KLHL3
Kelch-like protein 3

10

8

Small-scale

0.757

High

1294940

WNK1
Serine/threonine-protein kinase WNK1

2

18

Small-scale

0.754

High

117022

SGK1
Serine/threonine-protein kinase Sgk1

1

17

Small-scale

0.724

High

781415

BCL6
B-cell lymphoma 6 protein

1

1

Small-scale

0.691

High

681984

AKT1
RAC-alpha serine/threonine-protein kinase

1

17

Small-scale

0.647

High

1042287

CUL3
Cullin-3

3

9

Small-scale

0.640

High

307202

KLHL2
Kelch-like protein 2

2

8

Small-scale

0.633

High

1294942

STK39
STE20/SPS1-related proline-alanine-rich protein kinase

1

19

Small-scale

0.621

High

432158

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.618

High

438435

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.618

High

449796

HMGB1
High mobility group protein B1

1

4

Small-scale

0.508

High

1294939

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

15

Small-scale

0.501

High

647192

1433T
14-3-3 protein theta

1

20

High-throughput

0.479

High

684267

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

909911

1433E
14-3-3 protein epsilon

1

15

High-throughput

0.479

High

1185133

MAEA
E3 ubiquitin-protein transferase MAEA

1

6

Small-scale

0.479

High

1272535

CSN5
COP9 signalosome complex subunit 5

1

4

Small-scale

0.479

High

1294941

RMD5A
E3 ubiquitin-protein transferase RMND5A

1

6

Small-scale

0.479

High

1243886

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

927406

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.445

High

1269365

ESR2
Estrogen receptor beta

1

11

High-throughput

0.445

High


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Last updated: 15 Jul 2024