Protein: AIM2
Interferon-inducible protein AIM2 (Absent in melanoma 2)

Gene: AIM2
Organism: Homo sapiens
Interactions: 119
UniProt ID: O14862

Gene Ontology (top 5):
GO:0002218 - activation of innate immune response
GO:0002221 - pattern recognition receptor signaling pathway
GO:0002230 - positive regulation of defense response to virus by host
GO:0003690 - double-stranded DNA binding
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

157093

ASC
Apoptosis-associated speck-like protein containing a CARD

6

2

Small-scale

0.956

High

156983

AIM2
Interferon-inducible protein AIM2

4

4

Small-scale

0.881

High

157035

SQSTM
Sequestosome-1

2

1

Small-scale

0.571

High

117061

DX39A
ATP-dependent RNA helicase DDX39A

1

3

High-throughput

0.536

High

132050

PESC
Pescadillo homolog

1

3

High-throughput

0.536

High

132659

SDCB1
Syntenin-1

1

1

High-throughput

0.536

High

156984

HAT1
Histone acetyltransferase type B catalytic subunit

1

2

High-throughput

0.536

High

156988

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

10

High-throughput

0.536

High

156989

NBN
Nibrin

1

1

High-throughput

0.536

High

156992

MTA2
Metastasis-associated protein MTA2

1

3

High-throughput

0.536

High

156993

PHF14
PHD finger protein 14

1

3

High-throughput

0.536

High

156994

JUN
Transcription factor Jun

1

3

High-throughput

0.536

High

156995

AP2A
Transcription factor AP-2-alpha

1

2

High-throughput

0.536

High

156997

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

2

High-throughput

0.536

High

156999

XRCC6
X-ray repair cross-complementing protein 6

1

5

High-throughput

0.536

High

157000

XRCC5
X-ray repair cross-complementing protein 5

1

5

High-throughput

0.536

High

157001

RINI
Ribonuclease inhibitor

1

2

High-throughput

0.536

High

157002

TRI27
Zinc finger protein RFP

1

5

High-throughput

0.536

High

157006

CSK22
Casein kinase II subunit alpha'

1

3

High-throughput

0.536

High

157007

COT2
COUP transcription factor 2

1

3

High-throughput

0.536

High

157010

PML
Protein PML

1

7

High-throughput

0.536

High

157011

HXA13
Homeobox protein Hox-A13

1

1

High-throughput

0.536

High

157013

MTREX
Exosome RNA helicase MTR4

1

13

High-throughput

0.536

High

157014

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

3

High-throughput

0.536

High

157015

CTCF
Transcriptional repressor CTCF

1

3

High-throughput

0.536

High

157016

NU153
Nuclear pore complex protein Nup153

1

10

High-throughput

0.536

High

157017

DNLI3
DNA ligase 3

1

2

High-throughput

0.536

High

157018

MRE11
Double-strand break repair protein MRE11

1

1

High-throughput

0.536

High

157020

MECP2
Methyl-CpG-binding protein 2

1

4

High-throughput

0.536

High

157022

MSH6
DNA mismatch repair protein Msh6

1

4

High-throughput

0.536

High

157023

COPA
Coatomer subunit alpha

1

5

High-throughput

0.536

High

157024

HIRA
Protein HIRA

1

5

High-throughput

0.536

High

157025

DSRAD
Double-stranded RNA-specific adenosine deaminase

1

11

High-throughput

0.536

High

157027

PRS4
26S proteasome regulatory subunit 4

1

1

High-throughput

0.536

High

157030

TFAP4
Transcription factor AP-4

1

1

High-throughput

0.536

High

157031

RING1
E3 ubiquitin-protein ligase RING1

1

4

High-throughput

0.536

High

157033

FOXC1
Forkhead box protein C1

1

1

High-throughput

0.536

High

157034

MTA1
Metastasis-associated protein MTA1

1

3

High-throughput

0.536

High

157036

HDAC1
Histone deacetylase 1

1

2

High-throughput

0.536

High

157037

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

1

High-throughput

0.536

High

157038

SAFB2
Scaffold attachment factor B2

1

11

High-throughput

0.536

High

157039

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

4

High-throughput

0.536

High

157042

MDC1
Mediator of DNA damage checkpoint protein 1

1

9

High-throughput

0.536

High

157043

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

8

High-throughput

0.536

High

157044

SAFB1
Scaffold attachment factor B1

1

12

High-throughput

0.536

High

157045

RBBP7
Histone-binding protein RBBP7

1

8

High-throughput

0.536

High

157050

HMBX1
Homeobox-containing protein 1

1

2

High-throughput

0.536

High

157055

SUGP2
SURP and G-patch domain-containing protein 2

1

2

High-throughput

0.536

High

157056

RB12B
RNA-binding protein 12B

1

10

High-throughput

0.536

High

157058

LEMD2
LEM domain-containing protein 2

1

1

High-throughput

0.536

High

157063

P66B
Transcriptional repressor p66-beta

1

1

High-throughput

0.536

High

157064

DNJC9
DnaJ homolog subfamily C member 9

1

3

High-throughput

0.536

High

157065

H1X
Histone H1.10

1

3

High-throughput

0.536

High

157068

AP2C
Transcription factor AP-2 gamma

1

2

High-throughput

0.536

High

157069

RREB1
Ras-responsive element-binding protein 1

1

1

High-throughput

0.536

High

157070

HDAC2
Histone deacetylase 2

1

2

High-throughput

0.536

High

157071

RAD50
DNA repair protein RAD50

1

4

High-throughput

0.536

High

157072

RENT1
Regulator of nonsense transcripts 1

1

10

High-throughput

0.536

High

157074

STRBP
Spermatid perinuclear RNA-binding protein

1

10

High-throughput

0.536

High

157075

DDX50
ATP-dependent RNA helicase DDX50

1

7

High-throughput

0.536

High

157077

BC11A
B-cell lymphoma/leukemia 11A

1

1

High-throughput

0.536

High

157080

CHM4B
Charged multivesicular body protein 4b

1

1

High-throughput

0.536

High

157082

CYBP
Calcyclin-binding protein

1

2

High-throughput

0.536

High

157084

NCOA5
Nuclear receptor coactivator 5

1

1

High-throughput

0.536

High

157085

MOV10
Helicase MOV-10

1

10

High-throughput

0.536

High

157087

SLTM
SAFB-like transcription modulator

1

9

High-throughput

0.536

High

157088

RCC2
Protein RCC2

1

3

High-throughput

0.536

High

157089

PARP2
Poly [ADP-ribose] polymerase 2

1

3

High-throughput

0.536

High

157090

TCF20
Transcription factor 20

1

3

High-throughput

0.536

High

157091

MBD1
Methyl-CpG-binding domain protein 1

1

4

High-throughput

0.536

High

157094

SATB2
DNA-binding protein SATB2

1

2

High-throughput

0.536

High

157095

ZN148
Zinc finger protein 148

1

3

High-throughput

0.536

High

157097

LAS1L
Ribosomal biogenesis protein LAS1L

1

3

High-throughput

0.536

High

156986

ZBT39
Zinc finger and BTB domain-containing protein 39

1

0

High-throughput

0.513

High

156990

BAF
Barrier-to-autointegration factor

1

0

High-throughput

0.513

High

157003

XRCC1
DNA repair protein XRCC1

1

0

High-throughput

0.513

High

157005

TFE3
Transcription factor E3

1

0

High-throughput

0.513

High

157008

EF1B
Elongation factor 1-beta

1

0

High-throughput

0.513

High

157019

EMD
Emerin

1

0

High-throughput

0.513

High

157021

AL3A2
Aldehyde dehydrogenase family 3 member A2

1

0

High-throughput

0.513

High

157026

MAZ
Myc-associated zinc finger protein

1

0

High-throughput

0.513

High

157029

GTF2I
General transcription factor II-I

1

0

High-throughput

0.513

High

157032

TFCP2
Alpha-globin transcription factor CP2

1

0

High-throughput

0.513

High

157046

FSCN1
Fascin

1

0

High-throughput

0.513

High

157047

BEND3
BEN domain-containing protein 3

1

0

High-throughput

0.513

High

157053

KAISO
Transcriptional regulator Kaiso

1

0

High-throughput

0.513

High

157054

VRK3
Serine/threonine-protein kinase VRK3

1

0

High-throughput

0.513

High

157086

POTE1
Protection of telomeres protein 1

1

0

High-throughput

0.513

High

157009

CASP1
Caspase-1

1

1

Small-scale

0.494

High

156991

PRDM1
PR domain zinc finger protein 1

1

0

Small-scale

0.493

High

156996

NPM
Nucleophosmin

1

0

High-throughput

0.493

High

156985

ZN646
Zinc finger protein 646

1

1

High-throughput

0.489

High

157040

RCN2
Reticulocalbin-2

1

4

High-throughput

0.489

High

157048

H2A2A
Histone H2A type 2-A

1

2

High-throughput

0.489

High

157051

SAMD1
Sterile alpha motif domain-containing protein 1

1

3

High-throughput

0.489

High

157052

CE024
UPF0461 protein C5orf24

1

1

High-throughput

0.489

High

157059

ZBT44
Zinc finger and BTB domain-containing protein 44

1

2

High-throughput

0.489

High

157060

ZN740
Zinc finger protein 740

1

4

High-throughput

0.489

High

157061

ZN384
Zinc finger protein 384

1

1

High-throughput

0.489

High

157076

BC11B
B-cell lymphoma/leukemia 11B

1

1

High-throughput

0.489

High

157079

NKX24
Homeobox protein Nkx-2.4

1

2

High-throughput

0.489

High

157081

IKZF5
Zinc finger protein Pegasus

1

8

High-throughput

0.489

High

157096

ZN711
Zinc finger protein 711

1

2

High-throughput

0.489

High

157028

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.481

High

157067

AN32B
Acidic leucine-rich nuclear phosphoprotein 32 family member B

1

1

High-throughput

0.481

High

156987

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

157004

E2AK2
Interferon-induced, double-stranded RNA-activated protein kinase

1

1

Small-scale

0.479

High

157073

TRI11
E3 ubiquitin-protein ligase TRIM11

1

5

Small-scale

0.479

High

157092

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

1

2

Small-scale

0.479

High

157083

POPD3
Popeye domain-containing protein 3

1

1

Small-scale

0.470

High

157066

APBP2
Amyloid protein-binding protein 2

1

0

High-throughput

0.460

High

156998

IRF1
Interferon regulatory factor 1

1

0

Small-scale

0.458

High

157012

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

2

High-throughput

0.445

High

157041

BECN1
Beclin-1

1

0

Small-scale

0.426

High

157049

ZSC25
Zinc finger and SCAN domain-containing protein 25

1

0

High-throughput

0.279

Low

157057

ZN444
Zinc finger protein 444

1

0

High-throughput

0.279

Low

157062

THEM6
Protein THEM6

1

0

High-throughput

0.279

Low

157078

ADNP
Activity-dependent neuroprotector homeobox protein

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024