Protein: PLD6
Mitochondrial cardiolipin hydrolase (EC 3.1.4.-) (Choline phosphatase 6) (Mitochondrial phospholipase) (MitoPLD) (Phosphatidylcholine-hydrolyzing phospholipase D6) (Phospholipase D6) (PLD6) (Protein zucchini homolog)

Gene: PLD6
Organism: Homo sapiens
Interactions: 144
UniProt ID: Q8N2A8

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005794 - Golgi apparatus
GO:0007286 - spermatid development
GO:0008053 - mitochondrial fusion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1231455

SPP2B
Signal peptide peptidase-like 2B

2

2

High-throughput

0.628

High

1231474

KCNS3
Potassium voltage-gated channel subfamily S member 3

2

1

High-throughput

0.628

High

1231507

TDRKH
Tudor and KH domain-containing protein

2

3

High-throughput

0.611

High

777219

PEX19
Peroxisomal biogenesis factor 19

3

1

High-throughput

0.609

High

502316

BIP
Endoplasmic reticulum chaperone BiP

2

0

High-throughput

0.585

High

977414

KCNC4
Potassium voltage-gated channel subfamily C member 4

2

1

High-throughput

0.574

High

117181

DX39A
ATP-dependent RNA helicase DDX39A

1

1

High-throughput

0.553

High

687003

ACHA3
Neuronal acetylcholine receptor subunit alpha-3

1

2

High-throughput

0.536

High

1051886

IF4A2
Eukaryotic initiation factor 4A-II

1

0

High-throughput

0.517

High

439834

NEP
Neprilysin

1

0

High-throughput

0.513

High

768547

ADCY8
Adenylate cyclase type 8

1

0

High-throughput

0.513

High

871932

AT12A
Potassium-transporting ATPase alpha chain 2

1

0

High-throughput

0.513

High

487032

LYAG
Lysosomal alpha-glucosidase

1

1

High-throughput

0.489

High

677152

ACHB4
Neuronal acetylcholine receptor subunit beta-4

1

2

High-throughput

0.489

High

798523

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

1

2

High-throughput

0.489

High

1170263

LRC55
Leucine-rich repeat-containing protein 55

1

1

High-throughput

0.489

High

153021

IMPA2
Inositol monophosphatase 2

1

1

High-throughput

0.479

High

271597

ERAL1
GTPase Era, mitochondrial

1

1

High-throughput

0.479

High

565381

TMM11
Transmembrane protein 11, mitochondrial

1

1

High-throughput

0.479

High

670620

ERP29
Endoplasmic reticulum resident protein 29

1

2

High-throughput

0.479

High

718984

PHB1
Prohibitin 1

1

3

High-throughput

0.479

High

929559

RACK1
Small ribosomal subunit protein RACK1

1

1

High-throughput

0.479

High

933891

TBB4B
Tubulin beta-4B chain

1

1

High-throughput

0.479

High

1058474

GANAB
Neutral alpha-glucosidase AB

1

1

High-throughput

0.479

High

1072781

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

1

High-throughput

0.479

High

1173902

UBP30
Ubiquitin carboxyl-terminal hydrolase 30

1

1

High-throughput

0.479

High

1223954

CHSS2
Chondroitin sulfate synthase 2

1

1

High-throughput

0.479

High

1231451

ATAD1
Outer mitochondrial transmembrane helix translocase

1

1

High-throughput

0.479

High

1231456

HM13
Minor histocompatibility antigen H13

1

2

High-throughput

0.479

High

1231464

AKAP1
A-kinase anchor protein 1, mitochondrial

1

2

High-throughput

0.479

High

1231470

EFGM
Elongation factor G, mitochondrial

1

1

High-throughput

0.479

High

1231473

PHB2
Prohibitin-2

1

3

High-throughput

0.479

High

1231475

TBA1C
Tubulin alpha-1C chain

1

3

High-throughput

0.479

High

1231481

TBB2B
Tubulin beta-2B chain

1

1

High-throughput

0.479

High

1231484

RAB34
Ras-related protein Rab-34

1

1

High-throughput

0.479

High

1231493

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

1

High-throughput

0.479

High

1231494

DJC11
DnaJ homolog subfamily C member 11

1

4

High-throughput

0.479

High

1231510

MTCH2
Mitochondrial carrier homolog 2

1

3

High-throughput

0.479

High

157607

MGST3
Glutathione S-transferase 3, mitochondrial

1

0

High-throughput

0.458

High

166439

PUR4
Phosphoribosylformylglycinamidine synthase

1

0

High-throughput

0.458

High

231123

OPA1
Dynamin-like GTPase OPA1, mitochondrial

1

0

High-throughput

0.458

High

260240

ENTP6
Ectonucleoside triphosphate diphosphohydrolase 6

1

0

High-throughput

0.458

High

444754

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

1

0

High-throughput

0.458

High

486412

RO60
RNA-binding protein RO60

1

0

High-throughput

0.458

High

702624

ACSL1
Long-chain-fatty-acid--CoA ligase 1

1

0

High-throughput

0.458

High

782932

GARS
Glycine--tRNA ligase

1

0

High-throughput

0.458

High

839329

CPT1A
Carnitine O-palmitoyltransferase 1, liver isoform

1

0

High-throughput

0.458

High

844613

RAB5C
Ras-related protein Rab-5C

1

0

High-throughput

0.458

High

958305

AT2C1
Calcium-transporting ATPase type 2C member 1

1

0

High-throughput

0.458

High

966730

PFKAP
ATP-dependent 6-phosphofructokinase, platelet type

1

0

High-throughput

0.458

High

1023296

TRI32
E3 ubiquitin-protein ligase TRIM32

1

0

High-throughput

0.458

High

1028325

NDK3
Nucleoside diphosphate kinase 3

1

0

High-throughput

0.458

High

1186175

DYM
Dymeclin

1

0

High-throughput

0.458

High

1198735

PRUN1
Exopolyphosphatase PRUNE1

1

0

High-throughput

0.458

High

1220587

MIRO2
Mitochondrial Rho GTPase 2

1

0

High-throughput

0.458

High

1231454

COQ8A
Atypical kinase COQ8A, mitochondrial

1

0

High-throughput

0.458

High

1231466

S2546
Mitochondrial outer membrane protein SLC25A46

1

0

Small-scale

0.458

High

1231469

CNDP2
Cytosolic non-specific dipeptidase

1

0

High-throughput

0.458

High

1231476

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

1

0

High-throughput

0.458

High

1231489

ITM2C
Integral membrane protein 2C

1

0

High-throughput

0.458

High

1231492

CYRIB
CYFIP-related Rac1 interactor B

1

0

High-throughput

0.458

High

1231495

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.458

High

1231505

CPSF3
Cleavage and polyadenylation specificity factor subunit 3

1

0

High-throughput

0.458

High

1231508

ACOT9
Acyl-coenzyme A thioesterase 9, mitochondrial

1

0

High-throughput

0.458

High

161113

CLGN
Calmegin

1

1

High-throughput

0.437

High

172593

GNPAT
Dihydroxyacetone phosphate acyltransferase

1

1

High-throughput

0.437

High

263287

SC22B
Vesicle-trafficking protein SEC22b

1

2

High-throughput

0.437

High

654532

CALX
Calnexin

1

1

High-throughput

0.437

High

832134

PSB2
Proteasome subunit beta type-2

1

1

High-throughput

0.437

High

878690

HNRH2
Heterogeneous nuclear ribonucleoprotein H2

1

2

High-throughput

0.437

High

881643

PEX3
Peroxisomal biogenesis factor 3

1

1

High-throughput

0.437

High

1034490

OS9
Protein OS-9

1

1

High-throughput

0.437

High

1161395

SKI3
Superkiller complex protein 3

1

1

High-throughput

0.437

High

1231449

ARL10
ADP-ribosylation factor-like protein 10

1

4

High-throughput

0.437

High

1231465

RRF2M
Ribosome-releasing factor 2, mitochondrial

1

1

High-throughput

0.437

High

1231468

ERLEC
Endoplasmic reticulum lectin 1

1

1

High-throughput

0.437

High

1231483

GTPB2
GTP-binding protein 2

1

2

High-throughput

0.437

High

1231491

AAAS
Aladin

1

1

High-throughput

0.437

High

1231498

CHPF2
Chondroitin sulfate glucuronyltransferase

1

1

High-throughput

0.437

High

1231509

HYOU1
Hypoxia up-regulated protein 1

1

1

High-throughput

0.437

High

684201

1433S
14-3-3 protein sigma

3

0

High-throughput

0.347

High

1083459

C3AR
C3a anaphylatoxin chemotactic receptor

2

0

High-throughput

0.328

High

1165161

I27RA
Interleukin-27 receptor subunit alpha

2

0

High-throughput

0.328

High

1231461

SL9A6
Sodium/hydrogen exchanger 6

2

0

High-throughput

0.328

High

1100202

MICB
MHC class I polypeptide-related sequence B

2

0

High-throughput

0.318

High

198159

MSH5
MutS protein homolog 5

1

0

High-throughput

0.279

Low

253899

LRP3
Low-density lipoprotein receptor-related protein 3

1

0

High-throughput

0.279

Low

723885

SCN4A
Sodium channel protein type 4 subunit alpha

1

0

High-throughput

0.279

Low

884328

PCBP3
Poly(rC)-binding protein 3

1

0

High-throughput

0.279

Low

957433

IDD
Integral membrane protein DGCR2/IDD

1

0

High-throughput

0.279

Low

1035672

VPP3
V-type proton ATPase 116 kDa subunit a 3

1

0

High-throughput

0.279

Low

1125052

TTMP
TPA-induced transmembrane protein

1

0

High-throughput

0.279

Low

1231450

SIDT2
SID1 transmembrane family member 2

1

0

High-throughput

0.279

Low

1231457

MAGE2
Melanoma-associated antigen E2

1

0

High-throughput

0.279

Low

1231467

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

1

0

High-throughput

0.279

Low

1231471

JMJD8
JmjC domain-containing protein 8

1

0

High-throughput

0.279

Low

1231486

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.279

Low

1231504

GGT7
Glutathione hydrolase 7

1

0

High-throughput

0.279

Low

129492

MANBA
Beta-mannosidase

1

0

High-throughput

0.249

Low

238801

UGDH
UDP-glucose 6-dehydrogenase

1

0

High-throughput

0.249

Low

305309

NXPH4
Neurexophilin-4

1

0

High-throughput

0.249

Low

313083

AGM1
Phosphoacetylglucosamine mutase

1

0

High-throughput

0.249

Low

403921

ITB1
Integrin beta-1

1

0

High-throughput

0.249

Low

423289

PDIA1
Protein disulfide-isomerase

1

0

High-throughput

0.249

Low

438808

SRPRA
Signal recognition particle receptor subunit alpha

1

0

High-throughput

0.249

Low

1231463

GPI8
GPI-anchor transamidase

1

0

High-throughput

0.249

Low

1231472

P2RX4
P2X purinoceptor 4

1

0

High-throughput

0.249

Low

1231477

ESYT1
Extended synaptotagmin-1

1

0

High-throughput

0.249

Low

1231478

LRRC1
Leucine-rich repeat-containing protein 1

1

0

High-throughput

0.249

Low

571029

PYRG1
CTP synthase 1

1

0

High-throughput

0.249

Low

664183

PCSK6
Proprotein convertase subtilisin/kexin type 6

1

0

High-throughput

0.249

Low

839632

SERPH
Serpin H1

1

0

High-throughput

0.249

Low

878541

PSA
Puromycin-sensitive aminopeptidase

1

0

High-throughput

0.249

Low

896931

ARP2
Actin-related protein 2

1

0

High-throughput

0.249

Low

972784

PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

1

0

High-throughput

0.249

Low

986528

GFPT1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1

1

0

High-throughput

0.249

Low

995397

LG3BP
Galectin-3-binding protein

1

0

High-throughput

0.249

Low

1015912

NU160
Nuclear pore complex protein Nup160

1

0

High-throughput

0.249

Low

1055341

KPRA
Phosphoribosyl pyrophosphate synthase-associated protein 1

1

0

High-throughput

0.249

Low

1202788

LRP11
Low-density lipoprotein receptor-related protein 11

1

0

High-throughput

0.249

Low

1217046

PLD3
5'-3' exonuclease PLD3

1

0

High-throughput

0.249

Low

1231447

ABD12
Lysophosphatidylserine lipase ABHD12

1

0

High-throughput

0.249

Low

1231448

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.249

Low

1231452

DIK2A
Divergent protein kinase domain 2A

1

0

High-throughput

0.249

Low

1231453

NUP43
Nucleoporin Nup43

1

0

High-throughput

0.249

Low

1231458

NEUFC
Neuferricin

1

0

High-throughput

0.249

Low

1231459

MAIP1
m-AAA protease-interacting protein 1, mitochondrial

1

0

High-throughput

0.249

Low

1231460

RGP1
RAB6A-GEF complex partner protein 2

1

0

High-throughput

0.249

Low

1231462

GCN1
Stalled ribosome sensor GCN1

1

0

High-throughput

0.249

Low

1231479

FUCO2
Plasma alpha-L-fucosidase

1

0

High-throughput

0.249

Low

1231480

THTPA
Thiamine-triphosphatase

1

0

High-throughput

0.249

Low

1231482

NUP85
Nuclear pore complex protein Nup85

1

0

High-throughput

0.249

Low

1231485

UCK2
Uridine-cytidine kinase 2

1

0

High-throughput

0.249

Low

1231487

TRABD
TraB domain-containing protein

1

0

High-throughput

0.249

Low

1231488

RISC
Retinoid-inducible serine carboxypeptidase

1

0

High-throughput

0.249

Low

1231490

EI2BG
Translation initiation factor eIF2B subunit gamma

1

0

High-throughput

0.249

Low

1231496

UGGG1
UDP-glucose:glycoprotein glucosyltransferase 1

1

0

High-throughput

0.249

Low

1231497

HACD3
Very-long-chain

1

0

High-throughput

0.249

Low

1231499

TXD16
Thioredoxin domain-containing protein 16

1

0

High-throughput

0.249

Low

1231500

SE1L1
Protein sel-1 homolog 1

1

0

High-throughput

0.249

Low

1231501

SEC63
Translocation protein SEC63 homolog

1

0

High-throughput

0.249

Low

1231502

VATH
V-type proton ATPase subunit H

1

0

High-throughput

0.249

Low

1231503

XPO7
Exportin-7

1

0

High-throughput

0.249

Low

1231506

PP6R1
Serine/threonine-protein phosphatase 6 regulatory subunit 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024