Protein: TNR16
Tumor necrosis factor receptor superfamily member 16 (Gp80-LNGFR) (Low affinity neurotrophin receptor p75NTR) (Low-affinity nerve growth factor receptor) (NGF receptor) (Low-affinity nerve growth factor receptor p75NGFR) (Low-affinity nerve growth factor receptor p75NGR) (p75 ICD) (CD antigen CD271)

Gene: TNR16, NGFR
Organism: Homo sapiens
Interactions: 67
UniProt ID: P08138

Gene Ontology (top 5):
GO:0001540 - amyloid-beta binding
GO:0001678 - intracellular glucose homeostasis
GO:0004888 - transmembrane signaling receptor activity
GO:0005035 - death receptor activity
GO:0005516 - calmodulin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

351488

NGF
Beta-nerve growth factor

6

1

Small-scale

0.951

High

393954

A4
Amyloid-beta precursor protein

4

4

Small-scale

0.902

High

436603

TNR16
Tumor necrosis factor receptor superfamily member 16

3

15

Small-scale

0.834

High

436613

IRAK1
Interleukin-1 receptor-associated kinase 1

2

1

Small-scale

0.754

High

436611

CD80
T-lymphocyte activation antigen CD80

1

5

Small-scale

0.747

High

267337

TNR21
Tumor necrosis factor receptor superfamily member 21

1

15

Small-scale

0.724

High

436651

TRAF6
TNF receptor-associated factor 6

4

20

Small-scale

0.692

High

384118

NTRK1
High affinity nerve growth factor receptor

4

14

Small-scale

0.679

High

436639

NECD
Necdin

3

9

Small-scale

0.664

High

436621

SQSTM
Sequestosome-1

3

4

Small-scale

0.640

High

436634

LIGO1
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1

3

2

Small-scale

0.640

High

436638

SORT
Sortilin

3

8

Small-scale

0.640

High

436641

TRAF4
TNF receptor-associated factor 4

2

20

Small-scale

0.629

High

201745

RIPK2
Receptor-interacting serine/threonine-protein kinase 2

1

10

Small-scale

0.618

High

436608

NTF3
Neurotrophin-3

1

1

Small-scale

0.618

High

436625

TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein

1

10

Small-scale

0.618

High

436640

MYD88
Myeloid differentiation primary response protein MyD88

1

1

Small-scale

0.618

High

158372

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

2

17

Small-scale

0.584

High

436642

RTN4R
Reticulon-4 receptor

2

5

Small-scale

0.584

High

436652

MAGD1
Melanoma-associated antigen D1

2

9

Small-scale

0.584

High

436609

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

1

3

Small-scale

0.573

High

436635

NSE3
Non-structural maintenance of chromosomes element 3 homolog

1

9

Small-scale

0.573

High

436645

BFAR
Bifunctional apoptosis regulator

1

3

Small-scale

0.573

High

436643

MAGH1
Melanoma-associated antigen H1

2

9

Small-scale

0.570

High

385941

P53
Cellular tumor antigen p53

1

4

Small-scale

0.561

High

436618

TRAF2
TNF receptor-associated factor 2

1

20

Small-scale

0.561

High

225174

BNI3L
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

1

0

Small-scale

0.549

High

436628

FSCN1
Fascin

1

0

Small-scale

0.549

High

436615

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.537

High

436650

SALL2
Sal-like protein 2

1

7

Small-scale

0.535

High

436629

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

4

High-throughput

0.515

High

436647

CHIP
E3 ubiquitin-protein ligase CHIP

1

11

High-throughput

0.515

High

117242

PDLI1
PDZ and LIM domain protein 1

1

1

Small-scale

0.512

High

363555

TTHY
Transthyretin

1

1

High-throughput

0.508

High

378615

KITH
Thymidine kinase, cytosolic

1

1

High-throughput

0.508

High

436604

H2AX
Histone H2AX

1

1

High-throughput

0.508

High

436607

ANXA7
Annexin A7

1

3

High-throughput

0.508

High

436627

SMN
Survival motor neuron protein

1

1

High-throughput

0.508

High

436633

STMN2
Stathmin-2

1

1

High-throughput

0.508

High

301556

TRI37
E3 ubiquitin-protein ligase TRIM37

1

6

Small-scale

0.501

High

436605

EGR1
Early growth response protein 1

1

9

Small-scale

0.501

High

436617

CAV1
Caveolin-1

1

4

Small-scale

0.501

High

436636

SORC2
VPS10 domain-containing receptor SorCS2 [Cleaved into: SorCS2 122 kDa chain; SorCS2 104 kDa chain; SorCS2 18 kDa chain]

1

8

Small-scale

0.501

High

390665

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.486

High

436606

RCC1
Regulator of chromosome condensation

1

0

High-throughput

0.486

High

436612

CDN1A
Cyclin-dependent kinase inhibitor 1

1

0

High-throughput

0.486

High

436632

UFD1
Ubiquitin recognition factor in ER-associated degradation protein 1

1

0

High-throughput

0.486

High

129526

TRAF5
TNF receptor-associated factor 5

1

20

Small-scale

0.479

High

167447

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

18

Small-scale

0.479

High

436610

SHC1
SHC-transforming protein 1

1

11

Small-scale

0.479

High

436619

TRAF1
TNF receptor-associated factor 1

1

20

Small-scale

0.479

High

436620

TRAF3
TNF receptor-associated factor 3

1

20

Small-scale

0.479

High

436623

ITA9
Integrin alpha-9

1

3

Small-scale

0.479

High

436626

NTRK2
BDNF/NT-3 growth factors receptor

1

15

Small-scale

0.479

High

436630

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

20

Small-scale

0.479

High

436646

KDIS
Kinase D-interacting substrate of 220 kDa

1

3

Small-scale

0.479

High

436648

SORC3
VPS10 domain-containing receptor SorCS3

1

8

Small-scale

0.479

High

436614

BACE1
Beta-secretase 1

1

0

Small-scale

0.458

High

436616

BEX3
Protein BEX3

1

3

Small-scale

0.445

High

436622

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

6

High-throughput

0.445

High

436624

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

3

High-throughput

0.445

High

436631

TSC1
Hamartin

1

6

Small-scale

0.445

High

436637

SCN2A
Sodium channel protein type 2 subunit alpha

1

3

High-throughput

0.445

High

436644

BEX1
Protein BEX1

1

3

Small-scale

0.437

High

239721

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.426

High

436649

TCF19
Transcription factor 19

1

0

Small-scale

0.288

High


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024