Protein: BID
BH3-interacting domain death agonist (p22 BID) (BID) [Cleaved into: BH3-interacting domain death agonist p15 (p15 BID); BH3-interacting domain death agonist p13 (p13 BID); BH3-interacting domain death agonist p11 (p11 BID)]

Gene: BID
Organism: Homo sapiens
Interactions: 121
UniProt ID: P55957

Gene Ontology (top 5):
GO:0001836 - release of cytochrome c from mitochondria
GO:0005123 - death receptor binding
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

879514

B2CL1
Bcl-2-like protein 1

9

10

Small-scale

0.971

High

879515

MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1

7

10

Small-scale

0.970

High

489391

BCL2
Apoptosis regulator Bcl-2

8

10

Small-scale

0.963

High

879538

B2CL2
Bcl-2-like protein 2

5

10

Small-scale

0.931

High

879526

BAK
Bcl-2 homologous antagonist/killer

4

10

Small-scale

0.885

High

879513

BAX
Apoptosis regulator BAX

3

10

Small-scale

0.865

High

879525

B2LA1
Bcl-2-related protein A1

2

10

Small-scale

0.768

High

486159

GRAB
Granzyme B

9

2

Small-scale

0.754

High

879522

CASP8
Caspase-8

3

4

Small-scale

0.646

High

788172

CASP3
Caspase-3

2

4

Small-scale

0.633

High

788240

CASP2
Caspase-2

2

4

Small-scale

0.602

High

552354

RFA2
Replication protein A 32 kDa subunit

2

0

Small-scale

0.559

High

879503

BID
BH3-interacting domain death agonist

2

0

Small-scale

0.559

High

216478

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

1

0

High-throughput

0.549

High

879511

REL
Proto-oncogene c-Rel

1

0

High-throughput

0.549

High

683229

1433B
14-3-3 protein beta/alpha

1

1

Small-scale

0.515

High

862261

NUDT6
Nucleoside diphosphate-linked moiety X motif 6

1

0

High-throughput

0.513

High

879543

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.513

High

879544

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

0

High-throughput

0.513

High

595526

GRAH
Granzyme H

1

2

Small-scale

0.501

High

879508

CAV1
Caveolin-1

1

0

Small-scale

0.493

High

381886

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

0

High-throughput

0.486

High

690137

GBP2
Guanylate-binding protein 2

1

0

High-throughput

0.486

High

879510

TLE1
Transducin-like enhancer protein 1

1

0

High-throughput

0.486

High

879519

DPYL1
Dihydropyrimidinase-related protein 1

1

0

High-throughput

0.486

High

879529

FBN3
Fibrillin-3 [Cleaved into: Fibrillin-3 C-terminal peptide]

1

0

High-throughput

0.486

High

879561

ERG28
Ergosterol biosynthetic protein 28 homolog

1

0

High-throughput

0.486

High

568964

CAN2
Calpain-2 catalytic subunit

1

0

Small-scale

0.480

High

158434

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

1

Small-scale

0.479

High

161998

HNRDL
Heterogeneous nuclear ribonucleoprotein D-like

1

1

Small-scale

0.479

High

167504

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

1

Small-scale

0.479

High

503768

HSP7C
Heat shock cognate 71 kDa protein

1

1

Small-scale

0.479

High

613394

SFPQ
Splicing factor, proline- and glutamine-rich

1

1

Small-scale

0.479

High

713932

HS71L
Heat shock 70 kDa protein 1-like

1

1

Small-scale

0.479

High

751554

GRP75
Stress-70 protein, mitochondrial

1

2

Small-scale

0.479

High

879507

M2OM
Mitochondrial 2-oxoglutarate/malate carrier protein

1

1

Small-scale

0.479

High

879533

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

1

Small-scale

0.479

High

879537

CHD5
Chromodomain-helicase-DNA-binding protein 5

1

1

Small-scale

0.479

High

879541

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

1

Small-scale

0.479

High

879555

NOD2
Nucleotide-binding oligomerization domain-containing protein 2

1

1

Small-scale

0.479

High

879564

NOD1
Nucleotide-binding oligomerization domain-containing protein 1

1

1

Small-scale

0.479

High

879566

MTCH2
Mitochondrial carrier homolog 2

1

1

Small-scale

0.479

High

879567

NEMO
NF-kappa-B essential modulator

1

2

Small-scale

0.479

High

119940

AP3B1
AP-3 complex subunit beta-1

1

0

Small-scale

0.458

High

133946

DDX3X
ATP-dependent RNA helicase DDX3X

1

0

Small-scale

0.458

High

206733

B2L11
Bcl-2-like protein 11

1

0

Small-scale

0.458

High

268967

CSDE1
Cold shock domain-containing protein E1

1

0

Small-scale

0.458

High

273745

NU155
Nuclear pore complex protein Nup155

1

0

Small-scale

0.458

High

324303

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

390146

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

Small-scale

0.458

High

414841

CDK1
Cyclin-dependent kinase 1

1

0

Small-scale

0.458

High

418081

NPM
Nucleophosmin

1

0

High-throughput

0.458

High

430903

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

0

Small-scale

0.458

High

434468

FUMH
Fumarate hydratase, mitochondrial

1

0

Small-scale

0.458

High

509218

G6PD
Glucose-6-phosphate 1-dehydrogenase

1

0

Small-scale

0.458

High

606391

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

0

Small-scale

0.458

High

653944

MAP4
Microtubule-associated protein 4

1

0

Small-scale

0.458

High

657319

ABCD3
ATP-binding cassette sub-family D member 3

1

0

Small-scale

0.458

High

739045

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

0

Small-scale

0.458

High

768426

CAPG
Macrophage-capping protein

1

0

Small-scale

0.458

High

786292

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

0

Small-scale

0.458

High

799954

VDAC2
Voltage-dependent anion-selective channel protein 2

1

0

Small-scale

0.458

High

818908

COPD
Coatomer subunit delta

1

0

Small-scale

0.458

High

874734

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

879504

IF4A1
Eukaryotic initiation factor 4A-I

1

0

Small-scale

0.458

High

879506

RL23A
Large ribosomal subunit protein uL23

1

0

Small-scale

0.458

High

879509

IF4G1
Eukaryotic translation initiation factor 4 gamma 1

1

0

Small-scale

0.458

High

879512

PRDX1
Peroxiredoxin-1

1

0

Small-scale

0.458

High

879518

SQSTM
Sequestosome-1

1

0

Small-scale

0.458

High

879520

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

0

Small-scale

0.458

High

879521

FLNC
Filamin-C

1

0

Small-scale

0.458

High

879524

PCBP2
Poly(rC)-binding protein 2

1

0

Small-scale

0.458

High

879530

MYH14
Myosin-14

1

0

Small-scale

0.458

High

879531

BRAP
BRCA1-associated protein

1

0

Small-scale

0.458

High

879532

RBBP6
E3 ubiquitin-protein ligase RBBP6

1

0

Small-scale

0.458

High

879534

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

0

Small-scale

0.458

High

879535

AHNK2
Protein AHNAK2

1

0

Small-scale

0.458

High

879542

MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

1

0

Small-scale

0.458

High

879545

CND3
Condensin complex subunit 3

1

0

Small-scale

0.458

High

879546

COR1B
Coronin-1B

1

0

Small-scale

0.458

High

879549

NAT10
RNA cytidine acetyltransferase

1

0

Small-scale

0.458

High

879550

ADT4
ADP/ATP translocase 4

1

0

Small-scale

0.458

High

879551

XRN2
5'-3' exoribonuclease 2

1

0

Small-scale

0.458

High

879552

PABP3
Polyadenylate-binding protein 3

1

0

Small-scale

0.458

High

879556

ABCF3
ATP-binding cassette sub-family F member 3

1

0

Small-scale

0.458

High

879558

EP15R
Epidermal growth factor receptor substrate 15-like 1

1

0

Small-scale

0.458

High

879559

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

154331

TR10B
Tumor necrosis factor receptor superfamily member 10B

1

2

Small-scale

0.445

High

546991

EZRI
Ezrin

1

1

Small-scale

0.445

High

584356

TNR1A
Tumor necrosis factor receptor superfamily member 1A

1

2

Small-scale

0.445

High

632229

TNR6
Tumor necrosis factor receptor superfamily member 6

1

2

Small-scale

0.445

High

640079

MOES
Moesin

1

1

Small-scale

0.445

High

815668

TNFL6
Tumor necrosis factor ligand superfamily member 6

1

1

Small-scale

0.445

High

879517

FADD
FAS-associated death domain protein

1

2

Small-scale

0.445

High

879539

CASPA
Caspase-10

1

4

Small-scale

0.445

High

879516

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

1

Small-scale

0.437

High

879563

LIMC1
LIM and calponin homology domains-containing protein 1

1

1

Small-scale

0.437

High

800735

MK08
Mitogen-activated protein kinase 8

1

0

Small-scale

0.426

High

854755

GDIR1
Rho GDP-dissociation inhibitor 1

1

0

Small-scale

0.426

High

879505

RHOA
Transforming protein RhoA

1

0

Small-scale

0.426

High

650797

RFA1
Replication protein A 70 kDa DNA-binding subunit

3

0

Small-scale

0.346

High

879536

AR6P6
ADP-ribosylation factor-like protein 6-interacting protein 6

2

0

High-throughput

0.328

High

879557

MBD5
Methyl-CpG-binding domain protein 5

2

0

High-throughput

0.328

High

519374

FCG2A
Low affinity immunoglobulin gamma Fc region receptor II-a

2

0

High-throughput

0.318

High

879540

DDT4L
DNA damage-inducible transcript 4-like protein

2

0

High-throughput

0.316

High

879554

GSX1
GS homeobox 1

1

0

High-throughput

0.279

Low

879523

SETB1
Histone-lysine N-methyltransferase SETDB1

1

0

High-throughput

0.265

Low

879527

RBM48
RNA-binding protein 48

1

0

High-throughput

0.265

Low

879547

TBB2B
Tubulin beta-2B chain

1

0

High-throughput

0.265

Low

879548

CRNL1
Crooked neck-like protein 1

1

0

High-throughput

0.265

Low

879562

ZHX1
Zinc fingers and homeoboxes protein 1

1

0

High-throughput

0.265

Low

879565

PKHM1
Pleckstrin homology domain-containing family M member 1

1

0

High-throughput

0.265

Low

117266

PDLI1
PDZ and LIM domain protein 1

1

0

Small-scale

0.249

Low

260814

H2AY
Core histone macro-H2A.1

1

0

Small-scale

0.249

Low

551646

DESP
Desmoplakin

1

0

Small-scale

0.249

Low

577608

SON
Protein SON

1

0

Small-scale

0.249

Low

720089

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

879528

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

879553

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

879560

SEPT9
Septin-9

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024