Protein: SPT4H
Transcription elongation factor SPT4 (hSPT4) (DRB sensitivity-inducing factor 14 kDa subunit) (DSIF p14) (DRB sensitivity-inducing factor small subunit) (DSIF small subunit)

Gene: SPT4H, SUPT4H1
Organism: Homo sapiens
Interactions: 44
UniProt ID: P63272

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000993 - RNA polymerase II complex binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006355 - regulation of DNA-templated transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

123910

SPT5H
Transcription elongation factor SPT5

15

4

Small-scale

0.986

High

246565

MCE1
mRNA-capping enzyme

2

1

High-throughput

0.584

High

864938

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

1

High-throughput

0.536

High

930107

1433F
14-3-3 protein eta

1

3

High-throughput

0.536

High

930108

SSRP1
FACT complex subunit SSRP1

1

1

High-throughput

0.536

High

846741

SMCA2
Probable global transcription activator SNF2L2

1

0

High-throughput

0.518

High

930106

EWS
RNA-binding protein EWS

1

0

High-throughput

0.518

High

446578

SNRPA
U1 small nuclear ribonucleoprotein A

1

0

High-throughput

0.513

High

448606

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.513

High

508443

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.513

High

679692

FGF9
Fibroblast growth factor 9

1

0

High-throughput

0.513

High

909431

1433E
14-3-3 protein epsilon

1

0

High-throughput

0.513

High

911802

RUXF
Small nuclear ribonucleoprotein F

1

0

High-throughput

0.513

High

930110

FOXF2
Forkhead box protein F2

1

0

High-throughput

0.513

High

930114

PXK
PX domain-containing protein kinase-like protein

1

0

High-throughput

0.513

High

930118

RNF34
E3 ubiquitin-protein ligase RNF34

1

0

High-throughput

0.513

High

930120

TMA16
Translation machinery-associated protein 16

1

0

High-throughput

0.513

High

930124

PAK5
Serine/threonine-protein kinase PAK 5

1

0

High-throughput

0.513

High

930111

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.489

High

930126

MFHA1
Malignant fibrous histiocytoma-amplified sequence 1

1

1

High-throughput

0.489

High

646784

1433T
14-3-3 protein theta

1

3

High-throughput

0.489

High

904432

1433G
14-3-3 protein gamma

1

3

High-throughput

0.489

High

930112

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.486

High

394505

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

125357

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

2

High-throughput

0.479

High

886079

H2B1D
Histone H2B type 1-D

1

3

High-throughput

0.479

High

890947

PP4C
Serine/threonine-protein phosphatase 4 catalytic subunit

1

1

High-throughput

0.479

High

930122

H2B1L
Histone H2B type 1-L

1

2

High-throughput

0.479

High

346474

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

908335

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

930109

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.458

High

930117

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

930119

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

930121

MYCBP
c-Myc-binding protein

1

0

High-throughput

0.458

High

930123

SP110
Sp110 nuclear body protein

1

0

High-throughput

0.458

High

893533

SEM1
26S proteasome complex subunit SEM1

1

0

High-throughput

0.426

High

930115

CCD71
Coiled-coil domain-containing protein 71

1

0

High-throughput

0.279

Low

930116

DOK4
Docking protein 4

1

0

High-throughput

0.279

Low

146620

SOCS2
Suppressor of cytokine signaling 2

1

0

High-throughput

0.269

Low

117268

PDLI1
PDZ and LIM domain protein 1

1

0

High-throughput

0.265

Low

930125

NSG2
Neuronal vesicle trafficking-associated protein 2

1

0

High-throughput

0.265

Low

531787

PDIA4
Protein disulfide-isomerase A4

1

0

High-throughput

0.249

Low

930113

SEML
Putative protein SEM1, isoform 2

1

0

High-throughput

0.249

Low

444876

ANXA5
Annexin A5

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024