Protein: TBL2
Transducin beta-like protein 2 (WS beta-transducin repeats protein) (WS-betaTRP) (Williams-Beuren syndrome chromosomal region 13 protein)

Gene: TBL2
Organism: Homo sapiens
Interactions: 151
UniProt ID: Q9Y4P3

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0019901 - protein kinase binding
GO:0030968 - endoplasmic reticulum unfolded protein response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

714705

CNR2
Cannabinoid receptor 2

1

1

Small-scale

0.691

High

1016050

SCAP
Sterol regulatory element-binding protein cleavage-activating protein

1

18

High-throughput

0.691

High

370806

ESR1
Estrogen receptor

4

20

High-throughput

0.676

High

1349220

E2AK3
Eukaryotic translation initiation factor 2-alpha kinase 3

3

13

Small-scale

0.640

High

182234

PDPK1
3-phosphoinositide-dependent protein kinase 1

4

5

High-throughput

0.638

High

1355177

SEC63
Translocation protein SEC63 homolog

2

7

High-throughput

0.621

High

283067

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

19

High-throughput

0.618

High

626806

PTAFR
Platelet-activating factor receptor

1

2

High-throughput

0.618

High

1315176

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

2

High-throughput

0.618

High

1377076

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

4

High-throughput

0.618

High

1054118

GRB7
Growth factor receptor-bound protein 7

1

8

Small-scale

0.618

High

1203531

SKAP1
Src kinase-associated phosphoprotein 1

1

19

High-throughput

0.618

High

1319164

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

9

High-throughput

0.618

High

1327647

UBP44
Ubiquitin carboxyl-terminal hydrolase 44

1

15

High-throughput

0.595

High

229165

PRKN
E3 ubiquitin-protein ligase parkin

2

19

High-throughput

0.584

High

890537

SC61B
Protein transport protein Sec61 subunit beta

2

1

High-throughput

0.584

High

1284195

LRC59
Leucine-rich repeat-containing protein 59

2

7

High-throughput

0.584

High

702817

CADH5
Cadherin-5

2

5

High-throughput

0.574

High

199979

SPIT2
Kunitz-type protease inhibitor 2

2

3

High-throughput

0.558

High

885963

EVA1C
Protein eva-1 homolog C

2

1

High-throughput

0.558

High

182968

R113A
E3 ubiquitin-protein ligase RNF113A

1

1

High-throughput

0.553

High

714605

GRK5
G protein-coupled receptor kinase 5

1

8

High-throughput

0.553

High

1063707

SUZ12
Polycomb protein SUZ12

1

2

High-throughput

0.553

High

1067667

P2RY6
P2Y purinoceptor 6

1

4

High-throughput

0.553

High

1147001

A16L1
Autophagy-related protein 16-1

1

20

High-throughput

0.553

High

1172425

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.553

High

1331727

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.553

High

1343850

ANLN
Anillin

1

5

High-throughput

0.553

High

1357228

FZR1
Fizzy-related protein homolog

1

20

High-throughput

0.553

High

196237

RRP8
Ribosomal RNA-processing protein 8

1

2

High-throughput

0.536

High

269951

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

15

High-throughput

0.536

High

307149

RTN3
Reticulon-3

1

4

High-throughput

0.536

High

401200

RLA0
Large ribosomal subunit protein uL10

1

5

High-throughput

0.536

High

642701

RL13
Large ribosomal subunit protein eL13

1

3

High-throughput

0.536

High

1199470

LYRIC
Protein LYRIC

1

3

High-throughput

0.536

High

1283341

CCD47
PAT complex subunit CCDC47

1

2

High-throughput

0.536

High

508292

FGFR1
Fibroblast growth factor receptor 1

2

13

High-throughput

0.521

High

1153474

PKHA7
Pleckstrin homology domain-containing family A member 7

1

20

High-throughput

0.514

High

1053846

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

0

High-throughput

0.513

High

1125182

TTMP
TPA-induced transmembrane protein

1

0

High-throughput

0.513

High

1282505

NCLN
BOS complex subunit NCLN

1

0

High-throughput

0.513

High

1377893

TX264
Testis-expressed protein 264

1

0

High-throughput

0.513

High

180519

MAGB2
Melanoma-associated antigen B2

1

6

High-throughput

0.489

High

326261

TSN15
Tetraspanin-15

1

2

High-throughput

0.489

High

570392

HLAG
HLA class I histocompatibility antigen, alpha chain G

1

1

High-throughput

0.489

High

941884

GBRE
Gamma-aminobutyric acid receptor subunit epsilon

1

1

High-throughput

0.489

High

977430

KCNC4
Potassium voltage-gated channel subfamily C member 4

1

2

High-throughput

0.489

High

1032213

ITAD
Integrin alpha-D

1

2

High-throughput

0.489

High

1042924

CUL3
Cullin-3

1

20

High-throughput

0.489

High

1136858

FAXC
Failed axon connections homolog

1

1

High-throughput

0.489

High

1233075

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

1

High-throughput

0.489

High

1272734

CSN5
COP9 signalosome complex subunit 5

1

8

High-throughput

0.489

High

1343208

GPC5C
G-protein coupled receptor family C group 5 member C

1

2

High-throughput

0.489

High

1346728

EVA1B
Protein eva-1 homolog B

1

1

High-throughput

0.489

High

1357313

CLC4A
C-type lectin domain family 4 member A

1

2

High-throughput

0.489

High

1377890

PCDB3
Protocadherin beta-3

1

3

High-throughput

0.489

High

1377891

PCDGL
Protocadherin gamma-C4

1

3

High-throughput

0.489

High

1377892

WIF1
Wnt inhibitory factor 1

1

2

High-throughput

0.489

High

207676

AKA10
A-kinase anchor protein 10, mitochondrial

1

0

High-throughput

0.481

High

123125

MEN1
Menin

1

5

High-throughput

0.479

High

164049

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

2

High-throughput

0.479

High

168089

NPC1
NPC intracellular cholesterol transporter 1

1

2

High-throughput

0.479

High

298923

UFL1
E3 UFM1-protein ligase 1

1

2

High-throughput

0.479

High

349027

RASN
GTPase NRas

1

7

High-throughput

0.479

High

350726

RASK
GTPase KRas

1

6

High-throughput

0.479

High

360577

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

9

High-throughput

0.479

High

377831

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

391280

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.479

High

442630

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

9

High-throughput

0.479

High

545720

RAC2
Ras-related C3 botulinum toxin substrate 2

1

6

High-throughput

0.479

High

591171

BTF3
Transcription factor BTF3

1

3

High-throughput

0.479

High

649851

RL10
Large ribosomal subunit protein uL16

1

3

High-throughput

0.479

High

839251

EMD
Emerin

1

2

High-throughput

0.479

High

873167

PTN5
Tyrosine-protein phosphatase non-receptor type 5

1

2

High-throughput

0.479

High

901088

RHOA
Transforming protein RhoA

1

6

High-throughput

0.479

High

918200

H4
Histone H4

1

9

High-throughput

0.479

High

1022249

NFX1
Transcriptional repressor NF-X1

1

7

High-throughput

0.479

High

1062722

EMC2
ER membrane protein complex subunit 2

1

11

High-throughput

0.479

High

1066940

KIF14
Kinesin-like protein KIF14

1

9

High-throughput

0.479

High

1128564

HABP4
Intracellular hyaluronan-binding protein 4

1

4

High-throughput

0.479

High

1166103

LMBRL
Protein LMBR1L

1

1

High-throughput

0.479

High

1201804

ZCH18
Zinc finger CCCH domain-containing protein 18

1

20

High-throughput

0.479

High

1240850

RN149
E3 ubiquitin-protein ligase RNF149

1

5

High-throughput

0.479

High

1241087

SERB1
SERPINE1 mRNA-binding protein 1

1

4

High-throughput

0.479

High

1294178

DDRGK
DDRGK domain-containing protein 1

1

5

High-throughput

0.479

High

1296129

DNJC1
DnaJ homolog subfamily C member 1

1

13

High-throughput

0.479

High

1311464

ESYT1
Extended synaptotagmin-1

1

1

High-throughput

0.479

High

1328653

UN93B
Protein unc-93 homolog B1

1

2

High-throughput

0.479

High

1343322

RTN4
Reticulon-4

1

4

High-throughput

0.479

High

1377215

DJC16
DnaJ homolog subfamily C member 16

1

13

High-throughput

0.479

High

795349

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.458

High

1045378

APR
Phorbol-12-myristate-13-acetate-induced protein 1

1

0

High-throughput

0.458

High

1300818

PANX1
Pannexin-1

1

0

High-throughput

0.458

High

1303649

SEC62
Translocation protein SEC62

1

0

High-throughput

0.458

High

348347

MYC
Myc proto-oncogene protein

1

19

High-throughput

0.445

High

402671

JUN
Transcription factor Jun

1

12

High-throughput

0.445

High

1356723

AGO1
Protein argonaute-1

1

3

High-throughput

0.445

High

838376

MEOX2
Homeobox protein MOX-2

1

8

High-throughput

0.439

High

117465

BACH
Cytosolic acyl coenzyme A thioester hydrolase

1

1

High-throughput

0.437

High

125816

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

7

High-throughput

0.437

High

295455

RECQ4
ATP-dependent DNA helicase Q4

1

20

High-throughput

0.437

High

385787

NTRK1
High affinity nerve growth factor receptor

1

14

High-throughput

0.437

High

398151

ISG15
Ubiquitin-like protein ISG15

1

13

High-throughput

0.437

High

554151

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.437

High

652709

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.437

High

719665

MERL
Merlin

1

3

High-throughput

0.437

High

721874

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.437

High

780383

CCNF
Cyclin-F

1

8

High-throughput

0.437

High

781494

BCL6
B-cell lymphoma 6 protein

1

1

High-throughput

0.437

High

807889

MAP1B
Microtubule-associated protein 1B

1

9

High-throughput

0.437

High

818654

SOX2
Transcription factor SOX-2

1

20

High-throughput

0.437

High

835583

GSK3A
Glycogen synthase kinase-3 alpha

1

9

High-throughput

0.437

High

879869

TPTE
Putative tyrosine-protein phosphatase TPTE

1

3

High-throughput

0.437

High

999250

EP300
Histone acetyltransferase p300

1

16

High-throughput

0.437

High

1053705

GRM2
Metabotropic glutamate receptor 2

1

1

High-throughput

0.437

High

1156757

TECT3
Tectonic-3

1

1

High-throughput

0.437

High

1189105

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

6

High-throughput

0.437

High

1204875

GOLI
E3 ubiquitin-protein ligase RNF130

1

5

High-throughput

0.437

High

1235727

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

1

High-throughput

0.437

High

1239783

NHLC2
NHL repeat-containing protein 2

1

1

High-throughput

0.437

High

1244770

NUP35
Nucleoporin NUP35

1

1

High-throughput

0.437

High

1256512

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

4

High-throughput

0.437

High

1271007

KAT6A
Histone acetyltransferase KAT6A

1

20

High-throughput

0.437

High

1284284

CLUA1
Clusterin-associated protein 1

1

1

High-throughput

0.437

High

1291493

TSN17
Tetraspanin-17

1

3

High-throughput

0.437

High

1292909

TECT2
Tectonic-2

1

1

High-throughput

0.437

High

1304212

RING2
E3 ubiquitin-protein ligase RING2

1

18

High-throughput

0.437

High

1330903

Q9H4D1
Protein kinase

1

6

High-throughput

0.437

High

1342861

BRD7
Bromodomain-containing protein 7

1

19

High-throughput

0.437

High

1344478

ST7
Suppressor of tumorigenicity 7 protein

1

1

High-throughput

0.437

High

1348313

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

1

High-throughput

0.437

High

1348930

TLS1
Splicing factor C9orf78

1

4

High-throughput

0.437

High

1354181

HDAC6
Histone deacetylase 6

1

20

High-throughput

0.437

High

1354992

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.437

High

1357030

HECD1
E3 ubiquitin-protein ligase HECTD1

1

14

High-throughput

0.437

High

883689

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

6

High-throughput

0.407

High

967104

XPC
DNA repair protein complementing XP-C cells

1

1

High-throughput

0.407

High

1233286

RYBP
RING1 and YY1-binding protein

1

3

High-throughput

0.407

High

1318913

ZDHC5
Palmitoyltransferase ZDHHC5

1

5

High-throughput

0.407

High

560316

DPEP1
Dipeptidase 1

2

0

High-throughput

0.328

High

245449

RAMP3
Receptor activity-modifying protein 3

1

0

High-throughput

0.279

Low

259238

GLRA3
Glycine receptor subunit alpha-3

1

0

High-throughput

0.279

Low

362166

ACHA
Acetylcholine receptor subunit alpha

1

0

High-throughput

0.279

Low

1293561

TM169
Transmembrane protein 169

1

0

High-throughput

0.279

Low

1343110

TMM9B
Transmembrane protein 9B

1

0

High-throughput

0.279

Low

1079809

EREP1
Endosomal transmembrane epsin interactor 1

1

0

High-throughput

0.249

Low

1087641

CAH9
Carbonic anhydrase 9

1

0

High-throughput

0.249

Low

1221013

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

High-throughput

0.249

Low

1244017

FBX22
F-box only protein 22

1

0

High-throughput

0.249

Low

1303210

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.249

Low

1346223

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024