Protein: RASA1
Ras GTPase-activating protein 1 (GAP) (GTPase-activating protein) (RasGAP) (Ras p21 protein activator) (p120GAP)

Gene: RASA1
Organism: Homo sapiens
Interactions: 143
UniProt ID: P20936

Gene Ontology (top 5):
GO:0000281 - mitotic cytokinesis
GO:0001570 - vasculogenesis
GO:0001726 - ruffle
GO:0001784 - phosphotyrosine residue binding
GO:0001953 - negative regulation of cell-matrix adhesion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

596429

DOK1
Docking protein 1

9

20

Small-scale

0.966

High

349120

RASH
GTPase HRas

5

20

Small-scale

0.927

High

452350

PGFRB
Platelet-derived growth factor receptor beta

6

20

Small-scale

0.921

High

596435

RHG35
Rho GTPase-activating protein 35

4

14

Small-scale

0.890

High

337924

EGFR
Epidermal growth factor receptor

4

20

Small-scale

0.888

High

383603

ERBB2
Receptor tyrosine-protein kinase erbB-2

3

20

High-throughput

0.857

High

557601

NCK1
SH2/SH3 adapter protein NCK1

2

20

Small-scale

0.838

High

596428

RHG07
Rho GTPase-activating protein 7

2

13

Small-scale

0.827

High

580921

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

3

7

Small-scale

0.827

High

596362

EPHB2
Ephrin type-B receptor 2

2

20

Small-scale

0.812

High

596401

FAK2
Protein-tyrosine kinase 2-beta

2

20

Small-scale

0.806

High

348508

RASN
GTPase NRas

2

20

Small-scale

0.793

High

596357

ERBB3
Receptor tyrosine-protein kinase erbB-3

2

20

High-throughput

0.778

High

596404

ERBB4
Receptor tyrosine-protein kinase erbB-4

2

20

High-throughput

0.778

High

596400

GAB1
GRB2-associated-binding protein 1

2

20

Small-scale

0.777

High

181795

SOCS1
Suppressor of cytokine signaling 1

2

20

Small-scale

0.776

High

522768

SRC
Proto-oncogene tyrosine-protein kinase Src

2

20

Small-scale

0.768

High

147389

SOCS3
Suppressor of cytokine signaling 3

1

20

Small-scale

0.757

High

235043

DOK2
Docking protein 2

2

20

Small-scale

0.754

High

411293

INSR
Insulin receptor

2

20

Small-scale

0.754

High

596395

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

7

7

Small-scale

0.739

High

168729

ARC1B
Actin-related protein 2/3 complex subunit 1B

2

4

High-throughput

0.737

High

596359

S10A4
Protein S100-A4

2

8

High-throughput

0.737

High

596403

ACAP2
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2

2

20

High-throughput

0.737

High

596430

COR1B
Coronin-1B

2

12

High-throughput

0.737

High

596442

COR1C
Coronin-1C

2

11

High-throughput

0.737

High

435533

IGF1R
Insulin-like growth factor 1 receptor

1

20

Small-scale

0.734

High

442777

HCK
Tyrosine-protein kinase HCK

1

20

Small-scale

0.724

High

596383

EPHB3
Ephrin type-B receptor 3

1

20

Small-scale

0.724

High

596391

RACK1
Small ribosomal subunit protein RACK1

1

8

Small-scale

0.724

High

160378

AURKA
Aurora kinase A

1

10

High-throughput

0.698

High

210982

BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1

1

16

High-throughput

0.698

High

596367

BMR1A
Bone morphogenetic protein receptor type-1A

1

4

High-throughput

0.698

High

596373

DCC
Netrin receptor DCC

1

6

High-throughput

0.698

High

596398

PTPRJ
Receptor-type tyrosine-protein phosphatase eta

1

13

High-throughput

0.698

High

596406

STK11
Serine/threonine-protein kinase STK11

1

2

High-throughput

0.698

High

441429

MET
Hepatocyte growth factor receptor

1

20

High-throughput

0.692

High

499231

KIT
Mast/stem cell growth factor receptor Kit

1

20

High-throughput

0.692

High

411591

LCK
Tyrosine-protein kinase Lck

1

20

Small-scale

0.647

High

507850

FGFR1
Fibroblast growth factor receptor 1

1

20

Small-scale

0.647

High

596366

FLT3
Receptor-type tyrosine-protein kinase FLT3

1

20

Small-scale

0.647

High

596369

CSK
Tyrosine-protein kinase CSK

1

20

Small-scale

0.647

High

596414

ABI1
Abl interactor 1

1

20

Small-scale

0.647

High

596372

HD
Huntingtin

2

4

Small-scale

0.634

High

596415

AN36B
Ankyrin repeat domain-containing protein 36B

1

8

High-throughput

0.618

High

324737

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

20

Small-scale

0.618

High

337344

ABL1
Tyrosine-protein kinase ABL1

1

20

Small-scale

0.618

High

349874

RASK
GTPase KRas

1

20

Small-scale

0.618

High

384251

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.618

High

433252

YES
Tyrosine-protein kinase Yes

1

20

Small-scale

0.618

High

557030

PGFRA
Platelet-derived growth factor receptor alpha

1

20

Small-scale

0.618

High

596355

RASA1
Ras GTPase-activating protein 1

1

14

High-throughput

0.618

High

596361

EPHA2
Ephrin type-A receptor 2

1

20

High-throughput

0.618

High

596365

VGFR2
Vascular endothelial growth factor receptor 2

1

20

Small-scale

0.618

High

596374

ZAP70
Tyrosine-protein kinase ZAP-70

1

20

Small-scale

0.618

High

596390

GRB2
Growth factor receptor-bound protein 2

1

20

Small-scale

0.618

High

596411

TRI67
Tripartite motif-containing protein 67

1

15

High-throughput

0.618

High

596424

SPSB1
SPRY domain-containing SOCS box protein 1

1

12

Small-scale

0.618

High

596384

EPHA4
Ephrin type-A receptor 4

1

20

High-throughput

0.590

High

596394

CAV1
Caveolin-1

2

8

Small-scale

0.585

High

167743

FYB1
FYN-binding protein 1

1

10

Small-scale

0.575

High

596396

DDR1
Epithelial discoidin domain-containing receptor 1

1

20

Small-scale

0.575

High

117585

MYO1C
Unconventional myosin-Ic

2

16

High-throughput

0.571

High

135365

PPP6
Serine/threonine-protein phosphatase 6 catalytic subunit

2

6

High-throughput

0.571

High

181297

ARPC5
Actin-related protein 2/3 complex subunit 5

2

2

High-throughput

0.571

High

225843

KPRB
Phosphoribosyl pyrophosphate synthase-associated protein 2

2

3

High-throughput

0.571

High

297293

MYO1D
Unconventional myosin-Id

2

18

High-throughput

0.571

High

388224

HSPB1
Heat shock protein beta-1

2

4

High-throughput

0.571

High

397266

ADT2
ADP/ATP translocase 2

2

7

High-throughput

0.571

High

503422

HSP7C
Heat shock cognate 71 kDa protein

2

6

High-throughput

0.571

High

515801

PRPS2
Ribose-phosphate pyrophosphokinase 2

2

3

High-throughput

0.571

High

542182

PLAK
Junction plakoglobin

2

11

High-throughput

0.571

High

596356

FLNA
Filamin-A

2

14

High-throughput

0.571

High

596368

GRP75
Stress-70 protein, mitochondrial

2

14

High-throughput

0.571

High

596375

CAPZB
F-actin-capping protein subunit beta

2

2

High-throughput

0.571

High

596377

FAS
Fatty acid synthase

2

2

High-throughput

0.571

High

596380

6PGD
6-phosphogluconate dehydrogenase, decarboxylating

2

1

High-throughput

0.571

High

596381

CAZA1
F-actin-capping protein subunit alpha-1

2

3

High-throughput

0.571

High

596385

ARPC4
Actin-related protein 2/3 complex subunit 4

2

2

High-throughput

0.571

High

596386

ACTB
Actin, cytoplasmic 1

2

14

High-throughput

0.571

High

596387

PRPS1
Ribose-phosphate pyrophosphokinase 1

2

3

High-throughput

0.571

High

596392

ACTG
Actin, cytoplasmic 2

2

14

High-throughput

0.571

High

596393

AKA12
A-kinase anchor protein 12

2

12

High-throughput

0.571

High

596397

TWF1
Twinfilin-1

2

8

High-throughput

0.571

High

596402

KPRA
Phosphoribosyl pyrophosphate synthase-associated protein 1

2

3

High-throughput

0.571

High

596408

DREB
Drebrin

2

13

High-throughput

0.571

High

596422

HS105
Heat shock protein 105 kDa

2

10

High-throughput

0.571

High

596433

RM44
Large ribosomal subunit protein mL44

2

1

High-throughput

0.571

High

596434

MAGE1
Melanoma-associated antigen E1

2

3

High-throughput

0.571

High

596443

DRG1
Developmentally-regulated GTP-binding protein 1

2

1

High-throughput

0.571

High

596445

RM42
Large ribosomal subunit protein mL42

2

1

High-throughput

0.571

High

596446

NS1BP
Influenza virus NS1A-binding protein

2

2

High-throughput

0.571

High

596379

CAV2
Caveolin-2

1

8

Small-scale

0.561

High

596426

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

3

Small-scale

0.561

High

596427

GMCL1
Germ cell-less protein-like 1

2

4

High-throughput

0.553

High

299757

PLPHP
Pyridoxal phosphate homeostasis protein

2

0

High-throughput

0.547

High

495971

MGST1
Microsomal glutathione S-transferase 1

2

0

High-throughput

0.547

High

596388

RUXE
Small nuclear ribonucleoprotein E

2

0

High-throughput

0.547

High

596389

RUXF
Small nuclear ribonucleoprotein F

2

0

High-throughput

0.547

High

596418

MTMRE
Myotubularin-related protein 14

2

0

High-throughput

0.547

High

596419

OLIG1
Oligodendrocyte transcription factor 1

2

2

High-throughput

0.542

High

414165

RB
Retinoblastoma-associated protein

1

1

High-throughput

0.541

High

596358

APC
Adenomatous polyposis coli protein

1

7

High-throughput

0.541

High

596382

PMS2
Mismatch repair endonuclease PMS2

1

1

High-throughput

0.541

High

596405

SMAD2
Mothers against decapentaplegic homolog 2

1

1

High-throughput

0.541

High

436066

ANXA6
Annexin A6

1

6

Small-scale

0.536

High

487126

ANDR
Androgen receptor

1

11

High-throughput

0.536

High

410605

CD5
T-cell surface glycoprotein CD5

1

2

Small-scale

0.536

High

596378

ACADV
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial

2

2

High-throughput

0.521

High

596437

TMOD3
Tropomodulin-3

2

4

High-throughput

0.521

High

330230

BCL10
B-cell lymphoma/leukemia 10

1

0

High-throughput

0.518

High

385840

CPNS1
Calpain small subunit 1

1

13

Small-scale

0.515

High

523517

XRCC6
X-ray repair cross-complementing protein 6

1

3

High-throughput

0.508

High

596413

TRM2A
tRNA

1

1

High-throughput

0.508

High

394106

A4
Amyloid-beta precursor protein

1

6

High-throughput

0.501

High

596440

MLH3
DNA mismatch repair protein Mlh3

1

1

High-throughput

0.494

High

596370

EIF1
Eukaryotic translation initiation factor 1

1

0

High-throughput

0.486

High

596371

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

18

High-throughput

0.481

High

596439

SL9A2
Sodium/hydrogen exchanger 2

1

0

Small-scale

0.480

High

208320

SPY1
Protein sprouty homolog 1

1

10

Small-scale

0.479

High

568243

ATF7
Cyclic AMP-dependent transcription factor ATF-7

1

2

High-throughput

0.479

High

596364

SDC2
Syndecan-2

1

3

Small-scale

0.479

High

596376

PAXI
Paxillin

1

11

Small-scale

0.479

High

596399

G3BP1
Ras GTPase-activating protein-binding protein 1

1

4

Small-scale

0.479

High

596410

RNF43
E3 ubiquitin-protein ligase RNF43

1

9

High-throughput

0.479

High

596431

RIOK1
Serine/threonine-protein kinase RIO1

1

3

High-throughput

0.479

High

596407

EZH2
Histone-lysine N-methyltransferase EZH2

1

5

High-throughput

0.464

High

596436

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

Small-scale

0.458

High

596421

TSC1
Hamartin

1

18

Small-scale

0.457

High

596416

ARF
Tumor suppressor ARF

1

0

High-throughput

0.438

High

596360

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.437

High

596409

RM02
Large ribosomal subunit protein uL2m

2

0

High-throughput

0.298

High

596412

RM10
Large ribosomal subunit protein uL10m

2

0

High-throughput

0.298

High

596423

RM24
Large ribosomal subunit protein uL24m

2

0

High-throughput

0.298

High

596425

RM53
Large ribosomal subunit protein mL53

2

0

High-throughput

0.298

High

596432

RM18
Large ribosomal subunit protein uL18m

2

0

High-throughput

0.298

High

596438

RM15
Large ribosomal subunit protein uL15m

2

0

High-throughput

0.298

High

596441

DPP2
Dipeptidyl peptidase 2

2

0

High-throughput

0.298

High

596444

RM11
Large ribosomal subunit protein uL11m

2

0

High-throughput

0.298

High

596363

KAIN
Kallistatin

1

0

High-throughput

0.265

Low

596417

ZN579
Zinc finger protein 579

1

0

High-throughput

0.265

Low

596420

BBS10
Bardet-Biedl syndrome 10 protein

1

0

High-throughput

0.265

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024