Protein: RHG21
Rho GTPase-activating protein 21 (Rho GTPase-activating protein 10) (Rho-type GTPase-activating protein 21)

Gene: RHG21, ARHGAP21
Organism: Homo sapiens
Interactions: 170
UniProt ID: Q5T5U3

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005096 - GTPase activator activity
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1133709

ANLN
Anillin

2

3

High-throughput

0.789

High

900564

RHOA
Transforming protein RhoA

2

20

High-throughput

0.768

High

350234

RASK
GTPase KRas

2

15

High-throughput

0.754

High

915737

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.754

High

960375

CDK16
Cyclin-dependent kinase 16

2

3

High-throughput

0.737

High

927135

1433Z
14-3-3 protein zeta/delta

5

20

High-throughput

0.714

High

646969

1433T
14-3-3 protein theta

4

20

High-throughput

0.694

High

683416

1433B
14-3-3 protein beta/alpha

4

20

High-throughput

0.694

High

904676

1433G
14-3-3 protein gamma

4

20

High-throughput

0.694

High

982104

1433F
14-3-3 protein eta

4

20

High-throughput

0.694

High

1021671

MYO1E
Unconventional myosin-Ie

1

5

High-throughput

0.691

High

1133693

MY18A
Unconventional myosin-XVIIIa

1

4

High-throughput

0.691

High

717149

CTNB1
Catenin beta-1

4

9

Small-scale

0.666

High

716707

CTNA1
Catenin alpha-1

3

5

High-throughput

0.633

High

909650

1433E
14-3-3 protein epsilon

2

11

High-throughput

0.621

High

324818

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

9

High-throughput

0.618

High

120481

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

318156

DIRA3
GTP-binding protein Di-Ras3

1

3

High-throughput

0.618

High

349384

RASH
GTPase HRas

1

10

High-throughput

0.618

High

411755

LCK
Tyrosine-protein kinase Lck

1

20

High-throughput

0.618

High

433814

LYN
Tyrosine-protein kinase Lyn

1

20

High-throughput

0.618

High

545426

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.618

High

557714

NCK1
SH2/SH3 adapter protein NCK1

1

20

High-throughput

0.618

High

561393

FER
Tyrosine-protein kinase Fer

1

20

High-throughput

0.618

High

564562

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.618

High

822288

KC1D
Casein kinase I isoform delta

1

10

High-throughput

0.618

High

830389

KC1E
Casein kinase I isoform epsilon

1

14

High-throughput

0.618

High

835398

GSK3A
Glycogen synthase kinase-3 alpha

1

12

High-throughput

0.618

High

835811

GSK3B
Glycogen synthase kinase-3 beta

1

12

High-throughput

0.618

High

876410

AFAD
Afadin

1

20

High-throughput

0.618

High

891826

ACTB
Actin, cytoplasmic 1

1

18

High-throughput

0.618

High

892420

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

894109

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.618

High

895119

RAB2A
Ras-related protein Rab-2A

1

3

High-throughput

0.618

High

897369

ARF3
ADP-ribosylation factor 3

1

8

High-throughput

0.618

High

901178

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.618

High

912946

ARF6
ADP-ribosylation factor 6

1

8

High-throughput

0.618

High

925343

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

950502

ARF1
ADP-ribosylation factor 1

1

8

Small-scale

0.618

High

950634

ARF5
ADP-ribosylation factor 5

1

8

High-throughput

0.618

High

951062

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.618

High

1070234

RAB35
Ras-related protein Rab-35

1

1

High-throughput

0.618

High

1133670

RHG21
Rho GTPase-activating protein 21

1

15

Small-scale

0.618

High

1133690

PARD3
Partitioning defective 3 homolog

1

19

High-throughput

0.618

High

1133703

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.618

High

1133706

ECT2
Protein ECT2

1

7

High-throughput

0.618

High

1133707

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.618

High

1133715

ZO2
Tight junction protein ZO-2

1

8

High-throughput

0.618

High

521990

CADH1
Cadherin-1

2

9

High-throughput

0.611

High

1131444

SAPC1
Suppressor APC domain-containing protein 1

3

1

High-throughput

0.609

High

684094

1433S
14-3-3 protein sigma

2

20

High-throughput

0.601

High

1133672

CP135
Centrosomal protein of 135 kDa

2

6

High-throughput

0.584

High

1133722

NINL
Ninein-like protein

2

10

High-throughput

0.584

High

239149

CTND1
Catenin delta-1

2

8

High-throughput

0.571

High

427578

ANXA2
Annexin A2

2

1

High-throughput

0.571

High

999598

AHNK
Neuroblast differentiation-associated protein AHNAK

2

3

High-throughput

0.571

High

1133700

PKP4
Plakophilin-4

2

8

High-throughput

0.571

High

1133711

MAT2B
Methionine adenosyltransferase 2 subunit beta

2

1

High-throughput

0.571

High

669391

EF1D
Elongation factor 1-delta

1

0

High-throughput

0.554

High

1133674

CAVN1
Caveolae-associated protein 1

2

0

High-throughput

0.547

High

262478

TULP3
Tubby-related protein 3

1

3

High-throughput

0.541

High

317273

PCNT
Pericentrin

1

11

High-throughput

0.541

High

117724

MYO1C
Unconventional myosin-Ic

1

4

High-throughput

0.536

High

170665

AXIN1
Axin-1

1

1

High-throughput

0.536

High

323814

BAG2
BAG family molecular chaperone regulator 2

1

2

High-throughput

0.536

High

380789

S100B
Protein S100-B

1

9

High-throughput

0.536

High

598161

FLNA
Filamin-A

1

7

High-throughput

0.536

High

626158

APC
Adenomatous polyposis coli protein

1

3

High-throughput

0.536

High

685983

ARRB2
Beta-arrestin-2

1

3

High-throughput

0.536

High

724864

MYH9
Myosin-9

1

2

High-throughput

0.536

High

809327

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

7

High-throughput

0.536

High

813056

CAZA2
F-actin-capping protein subunit alpha-2

1

5

High-throughput

0.536

High

906489

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

2

High-throughput

0.536

High

1084969

DREB
Drebrin

1

2

High-throughput

0.536

High

1133682

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

2

High-throughput

0.536

High

1133685

SYNPO
Synaptopodin

1

4

High-throughput

0.536

High

1133697

MYO19
Unconventional myosin-XIX

1

6

High-throughput

0.536

High

1133705

EGLN3
Prolyl hydroxylase EGLN3

1

3

High-throughput

0.536

High

1133710

MYO5C
Unconventional myosin-Vc

1

1

High-throughput

0.536

High

1133717

LIMA1
LIM domain and actin-binding protein 1

1

7

High-throughput

0.536

High

531859

PDIA4
Protein disulfide-isomerase A4

2

4

High-throughput

0.521

High

1133699

PP1RA
Serine/threonine-protein phosphatase 1 regulatory subunit 10

2

2

High-throughput

0.521

High

1133704

PRR36
Proline-rich protein 36

2

5

High-throughput

0.521

High

435119

SP1
Transcription factor Sp1

1

15

High-throughput

0.512

High

161210

VP26C
Vacuolar protein sorting-associated protein 26C

1

1

High-throughput

0.494

High

595261

LMNB1
Lamin-B1

1

16

High-throughput

0.489

High

638980

S100P
Protein S100-P

1

10

High-throughput

0.489

High

648522

CALL3
Calmodulin-like protein 3

1

6

High-throughput

0.489

High

661290

S10A2
Protein S100-A2

1

10

High-throughput

0.489

High

1133714

FBLN5
Fibulin-5

1

2

High-throughput

0.489

High

1133720

PNMA2
Paraneoplastic antigen Ma2

1

5

High-throughput

0.489

High

162840

XPO1
Exportin-1

1

11

High-throughput

0.479

High

205499

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.479

High

215140

LANC1
Glutathione S-transferase LANCL1

1

1

High-throughput

0.479

High

236777

CCNT1
Cyclin-T1

1

2

High-throughput

0.479

High

279587

FLOT1
Flotillin-1

1

4

High-throughput

0.479

High

302532

CE152
Centrosomal protein of 152 kDa

1

5

High-throughput

0.479

High

341383

PLMN
Plasminogen

1

1

High-throughput

0.479

High

409106

K2C8
Keratin, type II cytoskeletal 8

1

2

High-throughput

0.479

High

416450

S10A9
Protein S100-A9

1

10

High-throughput

0.479

High

430214

PROF1
Profilin-1

1

9

High-throughput

0.479

High

507056

LAMP1
Lysosome-associated membrane glycoprotein 1

1

3

High-throughput

0.479

High

547091

EZRI
Ezrin

1

11

High-throughput

0.479

High

567103

CXA1
Gap junction alpha-1 protein

1

2

High-throughput

0.479

High

615755

GCSP
Glycine dehydrogenase

1

1

High-throughput

0.479

High

640115

MOES
Moesin

1

11

High-throughput

0.479

High

657506

TMOD1
Tropomodulin-1

1

2

High-throughput

0.479

High

678630

METK2
S-adenosylmethionine synthase isoform type-2

1

4

High-throughput

0.479

High

737857

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

2

High-throughput

0.479

High

742342

SYUA
Alpha-synuclein

1

3

High-throughput

0.479

High

749576

BRCA1
Breast cancer type 1 susceptibility protein

1

4

High-throughput

0.479

High

781915

PERI
Peripherin

1

10

High-throughput

0.479

High

818132

SOX2
Transcription factor SOX-2

1

5

High-throughput

0.479

High

840495

VASP
Vasodilator-stimulated phosphoprotein

1

5

High-throughput

0.479

High

969763

KIF23
Kinesin-like protein KIF23

1

5

High-throughput

0.479

High

974863

CAV1
Caveolin-1

1

2

High-throughput

0.479

High

990487

CKAP4
Cytoskeleton-associated protein 4

1

11

High-throughput

0.479

High

995380

LG3BP
Galectin-3-binding protein

1

3

High-throughput

0.479

High

1021414

ANK3
Ankyrin-3

1

10

High-throughput

0.479

High

1038444

HDAC1
Histone deacetylase 1

1

2

High-throughput

0.479

High

1051315

DCTN1
Dynactin subunit 1

1

7

High-throughput

0.479

High

1076971

MARE1
Microtubule-associated protein RP/EB family member 1

1

5

High-throughput

0.479

High

1080685

ZYX
Zyxin

1

8

High-throughput

0.479

High

1084036

OCLN
Occludin

1

3

High-throughput

0.479

High

1101100

CL16A
Protein CLEC16A

1

1

High-throughput

0.479

High

1124521

ODFP2
Outer dense fiber protein 2

1

4

High-throughput

0.479

High

1133673

RNF43
E3 ubiquitin-protein ligase RNF43

1

2

High-throughput

0.479

High

1133675

FIP1
Pre-mRNA 3'-end-processing factor FIP1

1

3

High-throughput

0.479

High

1133677

CE128
Centrosomal protein of 128 kDa

1

8

High-throughput

0.479

High

1133678

CNTRL
Centriolin

1

9

High-throughput

0.479

High

1133680

NAA40
N-alpha-acetyltransferase 40

1

2

High-throughput

0.479

High

1133681

DDX42
ATP-dependent RNA helicase DDX42

1

4

High-throughput

0.479

High

1133686

NIN
Ninein

1

11

High-throughput

0.479

High

1133688

NECP1
Adaptin ear-binding coat-associated protein 1

1

1

High-throughput

0.479

High

1133691

PPIL4
Peptidyl-prolyl cis-trans isomerase-like 4

1

3

High-throughput

0.479

High

1133702

CHM4B
Charged multivesicular body protein 4b

1

1

High-throughput

0.479

High

1133708

TRI36
E3 ubiquitin-protein ligase TRIM36

1

20

High-throughput

0.479

High

1133713

ANFY1
Rabankyrin-5

1

9

High-throughput

0.479

High

1133716

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.479

High

1133723

TRRAP
Transformation/transcription domain-associated protein

1

1

High-throughput

0.479

High

178583

STX7
Syntaxin-7

1

0

High-throughput

0.458

High

212864

STX6
Syntaxin-6

1

0

High-throughput

0.458

High

305491

ZFPL1
Zinc finger protein-like 1

1

0

High-throughput

0.458

High

908673

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

928613

DYLT1
Dynein light chain Tctex-type 1

1

0

High-throughput

0.458

High

1133689

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

1133712

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

High-throughput

0.458

High

484140

CALM3
Calmodulin-3

1

6

High-throughput

0.445

High

497161

TAU
Microtubule-associated protein tau

1

9

High-throughput

0.445

High

1133698

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

8

High-throughput

0.445

High

1032324

ZN177
Zinc finger protein 177

1

15

High-throughput

0.439

High

232219

KDM1A
Lysine-specific histone demethylase 1A

1

7

High-throughput

0.437

High

274552

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

3

High-throughput

0.437

High

396943

HMGN1
Non-histone chromosomal protein HMG-14

1

3

High-throughput

0.437

High

857479

HMGA2
High mobility group protein HMGI-C

1

1

High-throughput

0.437

High

1133676

SYNE3
Nesprin-3

1

6

High-throughput

0.437

High

1133679

PABP2
Polyadenylate-binding protein 2

1

7

High-throughput

0.437

High

1133683

PHF6
PHD finger protein 6

1

2

High-throughput

0.437

High

1133687

CE120
Centrosomal protein of 120 kDa

1

11

High-throughput

0.437

High

1133692

PSPC1
Paraspeckle component 1

1

10

High-throughput

0.437

High

1133694

CK052
Uncharacterized protein C11orf52

1

3

High-throughput

0.437

High

1133695

PF21A
PHD finger protein 21A

1

5

High-throughput

0.437

High

1133718

ATIF1
ATPase inhibitor, mitochondrial

1

2

High-throughput

0.437

High

1133719

RCOR1
REST corepressor 1

1

2

High-throughput

0.437

High

1133721

MARE3
Microtubule-associated protein RP/EB family member 3

1

5

High-throughput

0.437

High

1133671

BTBD8
BTB/POZ domain-containing protein 8

1

3

High-throughput

0.407

High

1133684

SPICE
Spindle and centriole-associated protein 1

1

0

High-throughput

0.249

Low

1133696

ENTR1
Endosome-associated-trafficking regulator 1

1

0

High-throughput

0.249

Low

1133701

NSRP1
Nuclear speckle splicing regulatory protein 1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024