Protein: ARF
Tumor suppressor ARF (Alternative reading frame) (ARF) (Cyclin-dependent kinase inhibitor 2A) (p14ARF)

Gene: ARF, CDKN2A
Organism: Homo sapiens
Interactions: 52
UniProt ID: Q8N726

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0000422 - autophagy of mitochondrion
GO:0002039 - p53 binding
GO:0003677 - DNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

962866

MDM2
E3 ubiquitin-protein ligase Mdm2

7

1

Small-scale

0.737

High

387103

P53
Cellular tumor antigen p53

4

1

Small-scale

0.666

High

418461

NPM
Nucleophosmin

3

1

Small-scale

0.633

High

1192124

HUWE1
E3 ubiquitin-protein ligase HUWE1

2

1

Small-scale

0.612

High

1056597

TRIPC
E3 ubiquitin-protein ligase TRIP12

1

2

Small-scale

0.578

High

1236874

CARF
CDKN2A-interacting protein

2

1

Small-scale

0.576

High

1236871

ZN420
Zinc finger protein 420

1

0

Small-scale

0.561

High

435139

SP1
Transcription factor Sp1

1

2

Small-scale

0.561

High

1236877

DAXX
Death domain-associated protein 6

1

0

Small-scale

0.538

High

379616

MYCN
N-myc proto-oncogene protein

1

1

Small-scale

0.515

High

575500

EGR1
Early growth response protein 1

1

2

Small-scale

0.515

High

963646

E2F1
Transcription factor E2F1

1

0

Small-scale

0.493

High

990177

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

Small-scale

0.493

High

737922

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

3

High-throughput

0.479

High

906535

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

3

High-throughput

0.479

High

1031906

MTA1
Metastasis-associated protein MTA1

1

1

Small-scale

0.479

High

829033

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

0

Small-scale

0.458

High

942802

SRPK2
SRSF protein kinase 2

1

1

High-throughput

0.445

High

1199070

MTA70
N6-adenosine-methyltransferase catalytic subunit

1

1

High-throughput

0.445

High

1236870

HIPK4
Homeodomain-interacting protein kinase 4

1

1

High-throughput

0.445

High

1236873

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

1

High-throughput

0.445

High

1236879

DYR1B
Dual specificity tyrosine-phosphorylation-regulated kinase 1B

1

1

High-throughput

0.445

High

239361

CC14B
Dual specificity protein phosphatase CDC14B

1

0

High-throughput

0.438

High

265916

FRAT2
GSK-3-binding protein FRAT2

1

0

High-throughput

0.438

High

349484

RASH
GTPase HRas

1

0

High-throughput

0.438

High

351420

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

0

High-throughput

0.438

High

393820

ALDOB
Fructose-bisphosphate aldolase B

1

0

High-throughput

0.438

High

596416

RASA1
Ras GTPase-activating protein 1

1

0

High-throughput

0.438

High

657526

TMOD1
Tropomodulin-1

1

0

High-throughput

0.438

High

890262

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.438

High

972226

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

1

0

High-throughput

0.438

High

1047985

BAAT
Bile acid-CoA:amino acid N-acyltransferase

1

0

High-throughput

0.438

High

1048044

CYLC2
Cylicin-2

1

0

High-throughput

0.438

High

1085118

MAPK3
MAP kinase-activated protein kinase 3

1

0

High-throughput

0.438

High

1151031

SFRP4
Secreted frizzled-related protein 4

1

0

High-throughput

0.438

High

1236175

AMPO
Aminopeptidase O

1

0

High-throughput

0.438

High

117764

MYO1C
Unconventional myosin-Ic

1

0

High-throughput

0.426

High

603594

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.426

High

803642

BAG6
Large proline-rich protein BAG6

1

0

High-throughput

0.426

High

1041398

CUL2
Cullin-2

1

0

High-throughput

0.426

High

1057541

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

0

High-throughput

0.426

High

1066038

ARHG6
Rho guanine nucleotide exchange factor 6

1

0

High-throughput

0.426

High

1085440

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.426

High

1236872

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.426

High

1236878

CD11A
Cyclin-dependent kinase 11A

1

0

High-throughput

0.426

High

245824

CATL2
Cathepsin L2

1

0

High-throughput

0.238

Low

1220911

GLT12
Polypeptide N-acetylgalactosaminyltransferase 12

1

0

High-throughput

0.238

Low

1223493

TEFF1
Tomoregulin-1

1

0

High-throughput

0.238

Low

1236875

CC180
Coiled-coil domain-containing protein 180

1

0

High-throughput

0.238

Low

230639

KATIP
Katanin-interacting protein

1

0

High-throughput

0.232

Low

787168

RHG25
Rho GTPase-activating protein 25

1

0

High-throughput

0.232

Low

1236876

CFA97
Cilia- and flagella-associated protein 97

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024