Protein: ILKAP
Integrin-linked kinase-associated serine/threonine phosphatase 2C (ILKAP) (EC 3.1.3.16)

Gene: ILKAP
Organism: Homo sapiens
Interactions: 86
UniProt ID: Q9H0C8

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0017018 - myosin phosphatase activity
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
GO:0043124 - negative regulation of canonical NF-kappaB signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

176274

PPM1G
Protein phosphatase 1G

1

2

High-throughput

0.691

High

154238

CHK1
Serine/threonine-protein kinase Chk1

1

20

Small-scale

0.647

High

850710

KS6A3
Ribosomal protein S6 kinase alpha-3

1

5

Small-scale

0.647

High

1082632

MK14
Mitogen-activated protein kinase 14

1

14

Small-scale

0.647

High

1261494

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

2

0

High-throughput

0.602

High

1033547

ILK
Integrin-linked protein kinase

1

5

Small-scale

0.573

High

1291572

OTUB1
Ubiquitin thioesterase OTUB1

2

0

High-throughput

0.547

High

169202

MUSK
Muscle, skeletal receptor tyrosine-protein kinase

1

20

High-throughput

0.541

High

338957

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.541

High

383969

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

High-throughput

0.541

High

499286

KIT
Mast/stem cell growth factor receptor Kit

1

12

High-throughput

0.541

High

665427

EPHA3
Ephrin type-A receptor 3

1

8

High-throughput

0.541

High

729688

VGFR2
Vascular endothelial growth factor receptor 2

1

12

High-throughput

0.541

High

968335

ROR1
Inactive tyrosine-protein kinase transmembrane receptor ROR1

1

20

High-throughput

0.541

High

968477

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

20

High-throughput

0.541

High

1031167

PTK7
Inactive tyrosine-protein kinase 7

1

10

High-throughput

0.541

High

1071009

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

High-throughput

0.541

High

117816

MYO1C
Unconventional myosin-Ic

1

1

High-throughput

0.536

High

296977

LTN1
E3 ubiquitin-protein ligase listerin

1

1

High-throughput

0.536

High

764691

CUX1
Homeobox protein cut-like 1

1

2

High-throughput

0.536

High

1035582

SMAD4
Mothers against decapentaplegic homolog 4

1

3

High-throughput

0.536

High

1191565

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

1

High-throughput

0.515

High

528026

RINI
Ribonuclease inhibitor

1

0

High-throughput

0.513

High

786635

STA5A
Signal transducer and activator of transcription 5A

1

0

High-throughput

0.513

High

883432

CF298
Cilia- and flagella-associated protein 298

1

0

High-throughput

0.513

High

911511

RS11
Small ribosomal subunit protein uS17

1

0

High-throughput

0.513

High

932049

TPM4
Tropomyosin alpha-4 chain

1

0

High-throughput

0.513

High

1245070

FBH1
F-box DNA helicase 1

1

0

High-throughput

0.513

High

1270244

TAF4B
Transcription initiation factor TFIID subunit 4B

1

0

High-throughput

0.513

High

175192

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

2

High-throughput

0.501

High

435754

IGF1R
Insulin-like growth factor 1 receptor

1

18

High-throughput

0.494

High

601994

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

20

High-throughput

0.494

High

665328

EPHA2
Ephrin type-A receptor 2

1

8

High-throughput

0.494

High

972365

TIE2
Angiopoietin-1 receptor

1

7

High-throughput

0.494

High

1168415

LMTK1
Serine/threonine-protein kinase LMTK1

1

20

High-throughput

0.494

High

1219443

LMTK2
Serine/threonine-protein kinase LMTK2

1

20

High-throughput

0.494

High

794121

MATR3
Matrin-3

1

0

High-throughput

0.493

High

214660

MYO1B
Unconventional myosin-Ib

1

1

High-throughput

0.489

High

1068077

PDK1
[Pyruvate dehydrogenase

1

2

High-throughput

0.489

High

1253805

CERK1
Ceramide kinase

1

2

High-throughput

0.489

High

160181

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

0

Small-scale

0.480

High

1327508

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

197086

PRP4
U4/U6 small nuclear ribonucleoprotein Prp4

1

1

High-throughput

0.479

High

228638

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

244916

BRD4
Bromodomain-containing protein 4

1

1

High-throughput

0.479

High

298786

UFL1
E3 UFM1-protein ligase 1

1

1

High-throughput

0.479

High

360394

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

1

High-throughput

0.479

High

455855

PARP1
Poly [ADP-ribose] polymerase 1

1

2

High-throughput

0.479

High

553665

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.479

High

617067

PTPRE
Receptor-type tyrosine-protein phosphatase epsilon

1

2

High-throughput

0.479

High

652199

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.479

High

668967

PML
Protein PML

1

2

High-throughput

0.479

High

909097

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

944418

PRKDC
DNA-dependent protein kinase catalytic subunit

1

1

High-throughput

0.479

High

952614

H33
Histone H3.3

1

2

High-throughput

0.479

High

1026533

RFA4
Replication protein A 30 kDa subunit

1

3

High-throughput

0.479

High

1029855

TIF1B
Transcription intermediary factor 1-beta

1

2

High-throughput

0.479

High

1327506

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

1327507

VDAC3
Voltage-dependent anion-selective channel protein 3

1

2

High-throughput

0.479

High

1327509

TRRAP
Transformation/transcription domain-associated protein

1

1

High-throughput

0.479

High

202523

PRPF3
U4/U6 small nuclear ribonucleoprotein Prp3

1

0

High-throughput

0.458

High

570053

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

621275

RIR1
Ribonucleoside-diphosphate reductase large subunit

1

0

High-throughput

0.458

High

736720

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.458

High

857510

HMGA2
High mobility group protein HMGI-C

1

0

Small-scale

0.458

High

918673

H2B1C
Histone H2B type 1-C/E/F/G/I

1

0

High-throughput

0.458

High

1027249

CBX3
Chromobox protein homolog 3

1

0

High-throughput

0.458

High

1188840

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1200651

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1221723

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1222567

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.458

High

1295731

MAEL
Protein maelstrom homolog

1

0

Small-scale

0.458

High

1327504

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

0

High-throughput

0.458

High

1281532

CNKR1
Connector enhancer of kinase suppressor of ras 1

1

2

Small-scale

0.457

High

402459

JUN
Transcription factor Jun

1

1

High-throughput

0.445

High

1327505

PTPRH
Receptor-type tyrosine-protein phosphatase H

1

2

High-throughput

0.445

High

721397

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

1171638

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.437

High

1293987

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.437

High

616928

PTPRB
Receptor-type tyrosine-protein phosphatase beta

1

2

High-throughput

0.407

High

261893

NDUS6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

2

0

High-throughput

0.328

High

680326

CASQ1
Calsequestrin-1

1

0

High-throughput

0.279

Low

851129

LUM
Lumican

1

0

High-throughput

0.279

Low

1085059

DREB
Drebrin

1

0

High-throughput

0.279

Low

1185578

CHSTF
Carbohydrate sulfotransferase 15

1

0

High-throughput

0.279

Low

1297195

CEP19
Centrosomal protein of 19 kDa

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024