Protein: RPA2
DNA-directed RNA polymerase I subunit RPA2 (RNA polymerase I subunit 2) (EC 2.7.7.6) (DNA-directed RNA polymerase I 135 kDa polypeptide) (RPA135)

Gene: RPA2, POLR1B
Organism: Homo sapiens
Interactions: 120
UniProt ID: Q9H9Y6

Gene Ontology (top 5):
GO:0001054 - RNA polymerase I activity
GO:0001650 - fibrillar center
GO:0003677 - DNA binding
GO:0003899 - DNA-directed 5'-3' RNA polymerase activity
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

317162

RPA1
DNA-directed RNA polymerase I subunit RPA1

8

20

Small-scale

0.967

High

169958

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

4

16

High-throughput

0.903

High

897631

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

4

8

High-throughput

0.903

High

1107793

RPA43
DNA-directed RNA polymerase I subunit RPA43

4

1

High-throughput

0.903

High

1326416

RPA49
DNA-directed RNA polymerase I subunit RPA49

4

5

Small-scale

0.886

High

921169

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

3

9

High-throughput

0.861

High

179827

RPA34
DNA-directed RNA polymerase I subunit RPA34

3

3

High-throughput

0.847

High

864991

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

2

6

High-throughput

0.789

High

1334517

RRN3
RNA polymerase I-specific transcription initiation factor RRN3

2

2

Small-scale

0.789

High

1334518

RPA12
DNA-directed RNA polymerase I subunit RPA12

2

13

High-throughput

0.789

High

583802

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

4

9

High-throughput

0.704

High

582500

NUCL
Nucleolin

1

1

High-throughput

0.691

High

682988

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

2

High-throughput

0.691

High

1203513

SKAP1
Src kinase-associated phosphoprotein 1

3

3

High-throughput

0.667

High

156068

RPC1
DNA-directed RNA polymerase III subunit RPC1

1

20

High-throughput

0.618

High

583587

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

16

High-throughput

0.618

High

625049

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

20

High-throughput

0.618

High

677011

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

10

High-throughput

0.618

High

738888

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

12

High-throughput

0.618

High

854474

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

1

9

High-throughput

0.618

High

913957

RPB7
DNA-directed RNA polymerase II subunit RPB7

1

11

High-throughput

0.618

High

1334513

RPC5
DNA-directed RNA polymerase III subunit RPC5

1

3

High-throughput

0.618

High

1334514

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

10

High-throughput

0.618

High

1334527

RPC10
DNA-directed RNA polymerase III subunit RPC10

1

12

High-throughput

0.618

High

1334528

RPC8
DNA-directed RNA polymerase III subunit RPC8

1

11

High-throughput

0.618

High

383983

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

1

Small-scale

0.611

High

854370

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

2

6

High-throughput

0.611

High

1334525

GPN3
GPN-loop GTPase 3

3

13

High-throughput

0.609

High

553749

RFA2
Replication protein A 32 kDa subunit

2

2

High-throughput

0.584

High

652288

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

3

High-throughput

0.584

High

721480

RFA3
Replication protein A 14 kDa subunit

2

2

High-throughput

0.584

High

850197

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

2

0

High-throughput

0.576

High

484481

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

9

High-throughput

0.575

High

370468

ESR1
Estrogen receptor

2

4

High-throughput

0.571

High

210503

ZN207
BUB3-interacting and GLEBS motif-containing protein ZNF207

1

1

High-throughput

0.541

High

622532

CCND1
G1/S-specific cyclin-D1

1

2

High-throughput

0.541

High

1334000

MED20
Mediator of RNA polymerase II transcription subunit 20

1

1

High-throughput

0.541

High

1334521

HDAC6
Histone deacetylase 6

1

1

High-throughput

0.541

High

853712

IMA5
Importin subunit alpha-5

1

4

High-throughput

0.536

High

1202128

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

3

High-throughput

0.536

High

1283590

TRI52
E3 ubiquitin-protein ligase TRIM52

1

2

High-throughput

0.536

High

1334021

WDR76
WD repeat-containing protein 76

1

6

High-throughput

0.536

High

1334509

GPN1
GPN-loop GTPase 1

1

13

High-throughput

0.536

High

902459

RL37
Large ribosomal subunit protein eL37

1

0

High-throughput

0.518

High

1050155

GIT2
ARF GTPase-activating protein GIT2

1

0

High-throughput

0.518

High

1199142

LDB1
LIM domain-binding protein 1

1

0

High-throughput

0.518

High

311762

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

1

0

High-throughput

0.513

High

686067

ARRB2
Beta-arrestin-2

1

0

High-throughput

0.513

High

1062972

MD2BP
MAD2L1-binding protein

1

0

High-throughput

0.513

High

1282427

FBXW5
F-box/WD repeat-containing protein 5

1

0

High-throughput

0.513

High

1334522

TRI10
Tripartite motif-containing protein 10

1

0

High-throughput

0.513

High

1235459

LZTR1
Leucine-zipper-like transcriptional regulator 1

1

1

High-throughput

0.494

High

847661

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.493

High

1332001

TAF1D
TATA box-binding protein-associated factor RNA polymerase I subunit D

1

0

High-throughput

0.493

High

246282

NBN
Nibrin

1

0

Small-scale

0.479

High

123014

MEN1
Menin

1

1

High-throughput

0.479

High

149305

CTRO
Citron Rho-interacting kinase

1

3

High-throughput

0.479

High

181458

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

3

High-throughput

0.479

High

270220

RPC9
DNA-directed RNA polymerase III subunit RPC9

1

3

High-throughput

0.479

High

295673

RMP
Unconventional prefoldin RPB5 interactor 1

1

2

High-throughput

0.479

High

309076

KI20A
Kinesin-like protein KIF20A

1

2

High-throughput

0.479

High

323161

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.479

High

347927

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.479

High

402751

RPC4
DNA-directed RNA polymerase III subunit RPC4

1

3

High-throughput

0.479

High

455886

PARP1
Poly [ADP-ribose] polymerase 1

1

1

High-throughput

0.479

High

557797

NCK1
SH2/SH3 adapter protein NCK1

1

2

High-throughput

0.479

High

603727

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

2

High-throughput

0.479

High

655472

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

1

High-throughput

0.479

High

824394

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.479

High

841328

CDK7
Cyclin-dependent kinase 7

1

5

High-throughput

0.479

High

897821

ABCE1
ATP-binding cassette sub-family E member 1

1

4

High-throughput

0.479

High

924874

GRB2
Growth factor receptor-bound protein 2

1

1

High-throughput

0.479

High

1029889

TIF1B
Transcription intermediary factor 1-beta

1

2

High-throughput

0.479

High

1034129

TCOF
Treacle protein

1

1

Small-scale

0.479

High

1035003

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

3

High-throughput

0.479

High

1064165

TNIP1
TNFAIP3-interacting protein 1

1

3

High-throughput

0.479

High

1066720

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.479

High

1076390

IKBB
NF-kappa-B inhibitor beta

1

2

High-throughput

0.479

High

1085961

IF16
Gamma-interferon-inducible protein 16

1

1

High-throughput

0.479

High

1101299

CL16A
Protein CLEC16A

1

1

High-throughput

0.479

High

1136300

RC3H1
Roquin-1

1

1

High-throughput

0.479

High

1137954

RPRD2
Regulation of nuclear pre-mRNA domain-containing protein 2

1

10

High-throughput

0.479

High

1171764

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.479

High

1221367

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

1

3

High-throughput

0.479

High

1236507

SIR6
NAD-dependent protein deacylase sirtuin-6

1

2

High-throughput

0.479

High

1269651

ESR2
Estrogen receptor beta

1

4

High-throughput

0.479

High

1298993

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

1

13

High-throughput

0.479

High

1332492

RPAP3
RNA polymerase II-associated protein 3

1

8

High-throughput

0.479

High

1332624

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.479

High

1334508

RC3H2
Roquin-2

1

5

High-throughput

0.479

High

1334510

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

1

14

High-throughput

0.479

High

1334511

ANLN
Anillin

1

1

High-throughput

0.479

High

1334519

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

1

High-throughput

0.479

High

1334520

UXT
Protein UXT

1

2

High-throughput

0.479

High

1334523

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

1334524

PFD2
Prefoldin subunit 2

1

2

High-throughput

0.479

High

682212

AKT2
RAC-beta serine/threonine-protein kinase

1

0

High-throughput

0.460

High

117828

MYO1C
Unconventional myosin-Ic

1

0

Small-scale

0.458

High

233638

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

842669

RL14
Large ribosomal subunit protein eL14

1

0

High-throughput

0.458

High

933056

ACTS
Actin, alpha skeletal muscle

1

0

Small-scale

0.458

High

1061068

NOLC1
Nucleolar and coiled-body phosphoprotein 1

1

0

Small-scale

0.458

High

1256406

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1286471

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

484416

RPC22
Protein POLR1D, isoform 2

1

1

High-throughput

0.445

High

1233208

RYBP
RING1 and YY1-binding protein

1

1

High-throughput

0.445

High

171677

PFD6
Prefoldin subunit 6

1

4

High-throughput

0.437

High

385542

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.437

High

1150698

GL1AD
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5

1

2

High-throughput

0.437

High

1298303

DAA10
Dynein axonemal assembly factor 10

1

2

High-throughput

0.437

High

1334512

PDRG1
p53 and DNA damage-regulated protein 1

1

2

High-throughput

0.437

High

1334515

PIHD1
PIH1 domain-containing protein 1

1

2

High-throughput

0.437

High

1334526

HECD1
E3 ubiquitin-protein ligase HECTD1

1

8

High-throughput

0.437

High

1201274

Q86V94
LOC554223 protein

2

0

High-throughput

0.318

High

1114453

AMZ1
Archaemetzincin-1

1

0

High-throughput

0.279

Low

1128371

SOLH1
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1

1

0

High-throughput

0.279

Low

1136843

FAXC
Failed axon connections homolog

1

0

High-throughput

0.279

Low

1239025

TEX19
Testis-expressed protein 19

1

0

High-throughput

0.279

Low

1087934

PTN21
Tyrosine-protein phosphatase non-receptor type 21

1

0

High-throughput

0.249

Low

1334516

GFOD1
Glucose-fructose oxidoreductase domain-containing protein 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024