Protein: CLD4
Claudin-4 (Clostridium perfringens enterotoxin receptor) (CPE-R) (CPE-receptor) (Williams-Beuren syndrome chromosomal region 8 protein)

Gene: CLD4, CLDN4
Organism: Homo sapiens
Interactions: 71
UniProt ID: O14493

Gene Ontology (top 5):
GO:0004888 - transmembrane signaling receptor activity
GO:0005198 - structural molecule activity
GO:0005254 - chloride channel activity
GO:0005886 - plasma membrane
GO:0005911 - cell-cell junction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

146001

FFAR2
Free fatty acid receptor 2

2

3

High-throughput

0.606

High

146020

ICAM3
Intercellular adhesion molecule 3

2

2

High-throughput

0.606

High

146023

CXA8
Gap junction alpha-8 protein

2

1

High-throughput

0.606

High

146035

AQP6
Aquaporin-6

2

4

High-throughput

0.606

High

146053

GOLM1
Golgi membrane protein 1

2

1

High-throughput

0.606

High

146045

TSPO2
Translocator protein 2

2

0

High-throughput

0.580

High

146052

SYT2
Synaptotagmin-2

2

0

High-throughput

0.580

High

146041

AR13B
ADP-ribosylation factor-like protein 13B

2

2

High-throughput

0.553

High

146042

TM52B
Transmembrane protein 52B

2

1

High-throughput

0.553

High

146043

F209A
Protein FAM209A

2

2

High-throughput

0.553

High

146046

DHB13
17-beta-hydroxysteroid dehydrogenase 13

2

2

High-throughput

0.553

High

146047

CLC14
C-type lectin domain family 14 member A

2

2

High-throughput

0.553

High

146030

ZO1
Tight junction protein ZO-1

1

20

Small-scale

0.501

High

146000

YKT6
Synaptobrevin homolog YKT6

1

1

Small-scale

0.479

High

146003

CTND1
Catenin delta-1

1

1

Small-scale

0.479

High

146006

EGFR
Epidermal growth factor receptor

1

2

Small-scale

0.479

High

146009

ITB1
Integrin beta-1

1

3

Small-scale

0.479

High

146010

YES
Tyrosine-protein kinase Yes

1

2

Small-scale

0.479

High

146013

PLAK
Junction plakoglobin

1

1

Small-scale

0.479

High

146014

ITB5
Integrin beta-5

1

1

Small-scale

0.479

High

146015

AT2B1
Plasma membrane calcium-transporting ATPase 1

1

1

Small-scale

0.479

High

146017

EPHA2
Ephrin type-A receptor 2

1

1

Small-scale

0.479

High

146018

EPHB2
Ephrin type-B receptor 2

1

2

Small-scale

0.479

High

146019

MARCS
Myristoylated alanine-rich C-kinase substrate

1

2

Small-scale

0.479

High

146021

MUC18
Cell surface glycoprotein MUC18

1

1

Small-scale

0.479

High

146022

NOTC1
Neurogenic locus notch homolog protein 1

1

1

Small-scale

0.479

High

146025

CXAR
Coxsackievirus and adenovirus receptor

1

1

Small-scale

0.479

High

146027

DSC2
Desmocollin-2

1

1

Small-scale

0.479

High

146029

NOTC2
Neurogenic locus notch homolog protein 2

1

2

Small-scale

0.479

High

146034

DLG1
Disks large homolog 1

1

3

Small-scale

0.479

High

146036

DSG2
Desmoglein-2

1

1

Small-scale

0.479

High

117925

SNP23
Synaptosomal-associated protein 23

1

0

Small-scale

0.458

High

145998

SPTN2
Spectrin beta chain, non-erythrocytic 2

1

0

Small-scale

0.458

High

146002

E41L2
Band 4.1-like protein 2

1

0

Small-scale

0.458

High

146005

CBPD
Carboxypeptidase D

1

0

Small-scale

0.458

High

146008

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

0

Small-scale

0.458

High

146011

4F2
Amino acid transporter heavy chain SLC3A2

1

0

Small-scale

0.458

High

146012

MPRI
Cation-independent mannose-6-phosphate receptor

1

0

Small-scale

0.458

High

146016

MARK3
MAP/microtubule affinity-regulating kinase 3

1

0

Small-scale

0.458

High

146024

RAB7A
Ras-related protein Rab-7a

1

0

Small-scale

0.458

High

146026

LAT1
Large neutral amino acids transporter small subunit 1

1

0

Small-scale

0.458

High

146028

AKA12
A-kinase anchor protein 12

1

0

Small-scale

0.458

High

146031

S20A2
Sodium-dependent phosphate transporter 2

1

0

Small-scale

0.458

High

146032

AHNK
Neuroblast differentiation-associated protein AHNAK

1

0

Small-scale

0.458

High

146039

AAAT
Neutral amino acid transporter B(0)

1

0

Small-scale

0.458

High

146040

OCLN
Occludin

1

0

Small-scale

0.458

High

146048

LIPB1
Liprin-beta-1

1

0

Small-scale

0.458

High

146049

LSR
Lipolysis-stimulated lipoprotein receptor

1

0

Small-scale

0.458

High

146055

FERM2
Fermitin family homolog 2

1

0

Small-scale

0.458

High

146056

KIRR1
Kin of IRRE-like protein 1

1

0

Small-scale

0.458

High

146057

DCBD2
Discoidin, CUB and LCCL domain-containing protein 2

1

0

Small-scale

0.458

High

146059

ERBIN
Erbin

1

0

Small-scale

0.458

High

146060

EHD1
EH domain-containing protein 1

1

0

Small-scale

0.458

High

146061

ADDG
Gamma-adducin

1

0

Small-scale

0.458

High

146062

CEIP2
Inactive cell surface hyaluronidase CEMIP2

1

0

Small-scale

0.458

High

146063

LCAP
Leucyl-cystinyl aminopeptidase

1

0

Small-scale

0.458

High

146064

S39AA
Zinc transporter ZIP10

1

0

Small-scale

0.458

High

146065

BAIP2
BAR/IMD domain-containing adapter protein 2

1

0

Small-scale

0.458

High

146067

S4A7
Sodium bicarbonate cotransporter 3

1

0

Small-scale

0.458

High

146004

IGSF3
Immunoglobulin superfamily member 3

1

1

Small-scale

0.437

High

146033

AP1B1
AP-1 complex subunit beta-1

1

1

Small-scale

0.437

High

146038

TRIPB
Thyroid receptor-interacting protein 11

1

1

Small-scale

0.437

High

146051

PHAR4
Phosphatase and actin regulator 4

1

2

Small-scale

0.437

High

146054

ESR2
Estrogen receptor beta

1

2

High-throughput

0.437

High

146044

MF14B
Hippocampus abundant transcript-like protein 1

2

0

High-throughput

0.316

High

146050

TRI59
Tripartite motif-containing protein 59

2

0

High-throughput

0.316

High

146058

TM237
Transmembrane protein 237

2

0

High-throughput

0.316

High

146007

SHBG
Sex hormone-binding globulin

1

0

Small-scale

0.251

Low

145999

PGRC2
Membrane-associated progesterone receptor component 2

1

0

Small-scale

0.249

Low

146037

GOGB1
Golgin subfamily B member 1

1

0

Small-scale

0.249

Low

146066

MAN1
Inner nuclear membrane protein Man1

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024