Protein: AGRL1
Adhesion G protein-coupled receptor L1 (Calcium-independent alpha-latrotoxin receptor 1) (CIRL-1) (Latrophilin-1) (Lectomedin-2)

Gene: AGRL1, ADGRL1
Organism: Homo sapiens
Interactions: 66
UniProt ID: O94910

Gene Ontology (top 5):
GO:0004930 - G protein-coupled receptor activity
GO:0005886 - plasma membrane
GO:0007157 - heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007166 - cell surface receptor signaling pathway
GO:0007186 - G protein-coupled receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

300346

NRG1
Pro-neuregulin-1, membrane-bound isoform

3

1

High-throughput

0.861

High

300373

VSIG4
V-set and immunoglobulin domain-containing protein 4

3

2

High-throughput

0.861

High

300370

FLRT1
Leucine-rich repeat transmembrane protein FLRT1

2

12

High-throughput

0.811

High

300327

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

4

High-throughput

0.691

High

300328

GPIX
Platelet glycoprotein IX

1

15

High-throughput

0.691

High

300337

EVA1C
Protein eva-1 homolog C

1

1

High-throughput

0.691

High

300349

EREP1
Endosomal transmembrane epsin interactor 1

3

1

High-throughput

0.667

High

245294

RAMP3
Receptor activity-modifying protein 3

1

0

High-throughput

0.656

High

300350

CC50B
Cell cycle control protein 50B

2

3

High-throughput

0.628

High

300361

GPR21
Probable G-protein coupled receptor 21

2

3

High-throughput

0.628

High

300371

CLC2D
C-type lectin domain family 2 member D

2

10

High-throughput

0.628

High

300372

PCDAC
Protocadherin alpha-12

2

7

High-throughput

0.628

High

300375

PCDGD
Protocadherin gamma-B1

2

10

High-throughput

0.628

High

300334

CD1B
T-cell surface glycoprotein CD1b

1

5

High-throughput

0.618

High

216370

EDIL3
EGF-like repeat and discoidin I-like domain-containing protein 3

3

3

High-throughput

0.609

High

300321

VNN2
Pantetheine hydrolase VNN2

2

0

High-throughput

0.602

High

300322

TSN15
Tetraspanin-15

2

14

High-throughput

0.601

High

206451

B4GA1
Beta-1,4-glucuronyltransferase 1

2

1

High-throughput

0.574

High

132277

CAC1A
Voltage-dependent P/Q-type calcium channel subunit alpha-1A

1

7

High-throughput

0.573

High

300331

APC
Adenomatous polyposis coli protein

1

1

High-throughput

0.541

High

300363

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

5

High-throughput

0.541

High

125949

UPK1A
Uroplakin-1a

1

17

High-throughput

0.536

High

131860

UPK2
Uroplakin-2

1

5

High-throughput

0.536

High

300330

ACHB2
Neuronal acetylcholine receptor subunit beta-2

1

3

High-throughput

0.536

High

300332

EDNRA
Endothelin-1 receptor

1

4

High-throughput

0.536

High

300335

SCN4A
Sodium channel protein type 4 subunit alpha

1

7

High-throughput

0.536

High

300344

EREP3
Protein ENTREP3

1

1

High-throughput

0.536

High

300347

KLRB1
Killer cell lectin-like receptor subfamily B member 1

1

11

High-throughput

0.536

High

300352

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

1

3

High-throughput

0.536

High

300355

TM11B
Transmembrane protease serine 11B

1

3

High-throughput

0.536

High

300364

TTYH1
Protein tweety homolog 1

1

2

High-throughput

0.536

High

267206

CLN5
Bis(monoacylglycero)phosphate synthase CLN5

1

0

High-throughput

0.513

High

300324

IL2RA
Interleukin-2 receptor subunit alpha

1

0

High-throughput

0.513

High

300340

VA0D1
V-type proton ATPase subunit d 1

1

0

High-throughput

0.513

High

300351

NKAI1
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1

1

0

High-throughput

0.513

High

300354

PCAT2
Lysophosphatidylcholine acyltransferase 2

1

0

High-throughput

0.513

High

300356

LSME2
Leucine-rich single-pass membrane protein 2

1

0

High-throughput

0.513

High

300362

TMM59
Transmembrane protein 59

1

0

High-throughput

0.513

High

300367

NRN1
Neuritin

1

0

High-throughput

0.513

High

300357

TM130
Transmembrane protein 130

1

1

High-throughput

0.489

High

300359

ZDH12
Palmitoyltransferase ZDHHC12

1

2

High-throughput

0.489

High

300374

TMED7
Transmembrane emp24 domain-containing protein 7

1

2

High-throughput

0.489

High

120252

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

300323

RASK
GTPase KRas

1

8

High-throughput

0.479

High

300325

LYN
Tyrosine-protein kinase Lyn

1

7

High-throughput

0.479

High

300326

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.479

High

300329

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.479

High

300338

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

300339

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

300341

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

300342

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.479

High

300343

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

300345

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

300365

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

300366

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

300369

CC50A
Cell cycle control protein 50A

1

3

High-throughput

0.479

High

300333

PSA3
Proteasome subunit alpha type-3

1

0

High-throughput

0.460

High

239662

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

3

High-throughput

0.445

High

300336

OR1D4
Olfactory receptor 1D4

1

3

High-throughput

0.445

High

300348

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

7

High-throughput

0.445

High

300320

KI20A
Kinesin-like protein KIF20A

1

3

High-throughput

0.437

High

300360

SNX27
Sorting nexin-27

1

13

High-throughput

0.437

High

300368

DISC1
Disrupted in schizophrenia 1 protein

1

1

High-throughput

0.417

High

300358

ZNRF4
E3 ubiquitin-protein ligase ZNRF4

2

0

High-throughput

0.328

High

118145

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.279

Low

300353

ARMC6
Armadillo repeat-containing protein 6

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024