Protein: MK10
Mitogen-activated protein kinase 10 (MAP kinase 10) (MAPK 10) (EC 2.7.11.24) (MAP kinase p49 3F12) (Stress-activated protein kinase 1b) (SAPK1b) (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3)

Gene: MK10, MAPK10
Organism: Homo sapiens
Interactions: 58
UniProt ID: P53779

Gene Ontology (top 5):
GO:0004705 - JUN kinase activity
GO:0004708 - MAP kinase kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

800973

MP2K4
Dual specificity mitogen-activated protein kinase kinase 4

3

20

Small-scale

0.845

High

864853

MK10
Mitogen-activated protein kinase 10

3

17

Small-scale

0.840

High

401690

JUN
Transcription factor Jun

9

20

Small-scale

0.759

High

864872

PMYT1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase

1

20

Small-scale

0.756

High

864868

DDI1
Protein DDI1 homolog 1

2

4

High-throughput

0.726

High

800865

MK09
Mitogen-activated protein kinase 9

1

17

High-throughput

0.691

High

864879

JIP3
C-Jun-amino-terminal kinase-interacting protein 3

3

19

Small-scale

0.679

High

864869

TCPW
T-complex protein 1 subunit zeta-2

3

18

High-throughput

0.667

High

659264

DUS1
Dual specificity protein phosphatase 1

1

20

Small-scale

0.665

High

864881

DUS10
Dual specificity protein phosphatase 10

1

20

Small-scale

0.665

High

349215

RASH
GTPase HRas

1

9

Small-scale

0.647

High

790960

CDN2C
Cyclin-dependent kinase 4 inhibitor C

1

15

Small-scale

0.647

High

804088

CDN1B
Cyclin-dependent kinase inhibitor 1B

1

12

Small-scale

0.647

High

864874

DUS9
Dual specificity protein phosphatase 9

1

20

Small-scale

0.647

High

827134

ARRB1
Beta-arrestin-1

3

9

Small-scale

0.646

High

547757

ATF2
Cyclic AMP-dependent transcription factor ATF-2

2

20

Small-scale

0.643

High

334167

LDHA
L-lactate dehydrogenase A chain

3

9

High-throughput

0.635

High

201919

WDR62
WD repeat-containing protein 62

2

15

High-throughput

0.628

High

546987

EZRI
Ezrin

2

12

High-throughput

0.628

High

640075

MOES
Moesin

2

12

High-throughput

0.628

High

864875

DUS16
Dual specificity protein phosphatase 16

1

20

Small-scale

0.618

High

864866

ZN239
Zinc finger protein 239

1

0

Small-scale

0.614

High

864855

TCPB
T-complex protein 1 subunit beta

2

18

High-throughput

0.611

High

685857

ARRB2
Beta-arrestin-2

2

9

Small-scale

0.595

High

118247

HAX1
HCLS1-associated protein X-1

2

0

High-throughput

0.588

High

790718

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

19

Small-scale

0.573

High

864857

TF65
Transcription factor p65

1

10

High-throughput

0.573

High

568080

JUND
Transcription factor JunD

1

20

Small-scale

0.569

High

584226

ELK1
ETS domain-containing protein Elk-1

1

20

Small-scale

0.569

High

864859

MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1

1

13

Small-scale

0.569

High

864856

MYT1
Myelin transcription factor 1

1

3

Small-scale

0.561

High

864877

HDAC9
Histone deacetylase 9

1

13

Small-scale

0.561

High

166682

CE290
Centrosomal protein of 290 kDa

1

12

High-throughput

0.541

High

864858

UBE3A
Ubiquitin-protein ligase E3A

1

4

High-throughput

0.541

High

864870

CBP
CREB-binding protein

1

10

High-throughput

0.541

High

864878

KI26A
Kinesin-like protein KIF26A

1

4

High-throughput

0.541

High

518619

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

2

High-throughput

0.536

High

719688

RADI
Radixin

1

12

High-throughput

0.536

High

864867

C1TM
Monofunctional C1-tetrahydrofolate synthase, mitochondrial

1

2

High-throughput

0.536

High

864860

TF3C1
General transcription factor 3C polypeptide 1

1

0

High-throughput

0.518

High

864863

U119A
Protein unc-119 homolog A

1

0

High-throughput

0.518

High

675820

GCH1
GTP cyclohydrolase 1

1

1

Small-scale

0.515

High

199310

ZW10
Centromere/kinetochore protein zw10 homolog

1

0

High-throughput

0.513

High

225233

3BP5
SH3 domain-binding protein 5

1

2

Small-scale

0.501

High

394391

A4
Amyloid-beta precursor protein

1

6

High-throughput

0.501

High

496629

TAU
Microtubule-associated protein tau

1

17

Small-scale

0.501

High

864861

KIF5A
Kinesin heavy chain isoform 5A

1

2

Small-scale

0.501

High

864862

JIP2
C-Jun-amino-terminal kinase-interacting protein 2

1

12

Small-scale

0.501

High

864880

FBX7
F-box only protein 7

1

1

High-throughput

0.501

High

864871

PLIN2
Perilipin-2

1

0

High-throughput

0.486

High

864865

TNIP1
TNFAIP3-interacting protein 1

1

6

High-throughput

0.481

High

864876

DBLOH
Diablo IAP-binding mitochondrial protein

1

0

Small-scale

0.480

High

386367

P53
Cellular tumor antigen p53

1

11

Small-scale

0.479

High

571371

DDX5
Probable ATP-dependent RNA helicase DDX5

1

6

High-throughput

0.479

High

864854

CTBP2
C-terminal-binding protein 2

1

4

High-throughput

0.479

High

864864

HDAC1
Histone deacetylase 1

1

8

Small-scale

0.479

High

864873

TCPH
T-complex protein 1 subunit eta

1

19

High-throughput

0.479

High


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Last updated: 15 Jul 2024