Protein: STXB1
Syntaxin-binding protein 1 (MUNC18-1) (N-Sec1) (Protein unc-18 homolog 1) (Unc18-1) (Protein unc-18 homolog A) (Unc-18A) (p67)

Gene: STXB1, STXBP1
Organism: Homo sapiens
Interactions: 123
UniProt ID: P61764

Gene Ontology (top 5):
GO:0000149 - SNARE binding
GO:0002576 - platelet degranulation
GO:0003006 - developmental process involved in reproduction
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

901809

STX19
Syntaxin-19

7

20

High-throughput

0.973

High

901790

STX1A
Syntaxin-1A

9

20

Small-scale

0.963

High

901780

STX3
Syntaxin-3

5

20

Small-scale

0.927

High

269405

STX11
Syntaxin-11

4

20

High-throughput

0.920

High

901778

STX5
Syntaxin-5

3

20

High-throughput

0.871

High

699253

STX2
Syntaxin-2

3

20

Small-scale

0.847

High

898829

STX1B
Syntaxin-1B

2

20

Small-scale

0.757

High

901818

SYTL4
Synaptotagmin-like protein 4

5

1

Small-scale

0.709

High

135018

TRI38
E3 ubiquitin-protein ligase TRIM38

4

1

High-throughput

0.709

High

394463

A4
Amyloid-beta precursor protein

3

3

Small-scale

0.667

High

566993

CXA1
Gap junction alpha-1 protein

3

9

High-throughput

0.667

High

496720

TAU
Microtubule-associated protein tau

3

7

Small-scale

0.656

High

118263

HAX1
HCLS1-associated protein X-1

3

0

High-throughput

0.638

High

901791

DGUOK
Deoxyguanosine kinase, mitochondrial

3

0

High-throughput

0.638

High

901793

BOREA
Borealin

3

0

High-throughput

0.638

High

901833

KTU
Protein kintoun

3

0

High-throughput

0.638

High

901834

ARMC1
Armadillo repeat-containing protein 1

3

0

High-throughput

0.638

High

901839

NUFP1
FMR1-interacting protein NUFIP1

3

0

High-throughput

0.638

High

901843

RRP7A
Ribosomal RNA-processing protein 7 homolog A

3

0

High-throughput

0.638

High

901782

TUSC3
Tumor suppressor candidate 3

2

1

High-throughput

0.628

High

901836

GPC5B
G-protein coupled receptor family C group 5 member B

2

7

High-throughput

0.628

High

901776

STX4
Syntaxin-4

1

20

Small-scale

0.618

High

901806

SPICE
Spindle and centriole-associated protein 1

2

1

High-throughput

0.606

High

901773

APBA1
Amyloid-beta A4 precursor protein-binding family A member 1

2

6

Small-scale

0.602

High

791448

HD
Huntingtin

2

2

High-throughput

0.588

High

227051

PRKN
E3 ubiquitin-protein ligase parkin

2

3

High-throughput

0.584

High

658878

MK01
Mitogen-activated protein kinase 1

2

0

High-throughput

0.580

High

901796

CENPP
Centromere protein P

2

0

High-throughput

0.580

High

837908

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.573

High

901824

APBA2
Amyloid-beta A4 precursor protein-binding family A member 2

2

6

Small-scale

0.571

High

865026

TTC3
E3 ubiquitin-protein ligase TTC3

1

5

High-throughput

0.541

High

336446

SODC
Superoxide dismutase [Cu-Zn]

1

1

High-throughput

0.536

High

678265

COR1A
Coronin-1A

1

1

High-throughput

0.536

High

816567

CXA8
Gap junction alpha-8 protein

1

9

High-throughput

0.536

High

901784

LAPM5
Lysosomal-associated transmembrane protein 5

1

1

High-throughput

0.536

High

901794

PLPP4
Phospholipid phosphatase 4

1

3

High-throughput

0.536

High

901805

KIBRA
Protein KIBRA

1

2

High-throughput

0.536

High

901812

MARH1
E3 ubiquitin-protein ligase MARCHF1

1

1

High-throughput

0.536

High

901814

S39A7
Zinc transporter SLC39A7

1

2

High-throughput

0.536

High

901816

HS105
Heat shock protein 105 kDa

1

3

High-throughput

0.536

High

901820

HVCN1
Voltage-gated hydrogen channel 1

1

2

High-throughput

0.536

High

901825

CML1
Chemerin-like receptor 1

1

2

High-throughput

0.536

High

261457

NCOR1
Nuclear receptor corepressor 1

1

3

High-throughput

0.515

High

780955

ID1
DNA-binding protein inhibitor ID-1

1

0

High-throughput

0.513

High

801055

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.513

High

849524

GPM6A
Neuronal membrane glycoprotein M6-a

1

0

High-throughput

0.513

High

901788

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

0

High-throughput

0.513

High

901801

URP2
Fermitin family homolog 3

1

0

High-throughput

0.513

High

901832

DJC11
DnaJ homolog subfamily C member 11

1

0

High-throughput

0.513

High

901840

DPOG2
DNA polymerase subunit gamma-2

1

0

High-throughput

0.513

High

815853

MTR1A
Melatonin receptor type 1A

1

1

High-throughput

0.508

High

901783

SQSTM
Sequestosome-1

1

0

Small-scale

0.505

High

159942

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

5

Small-scale

0.501

High

566345

KPCA
Protein kinase C alpha type

1

5

Small-scale

0.501

High

503813

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.500

High

157888

KLF11
Krueppel-like factor 11

1

0

High-throughput

0.493

High

602193

DRD4
D(4) dopamine receptor

1

0

High-throughput

0.493

High

796061

MAGA9
Melanoma-associated antigen 9

1

1

High-throughput

0.489

High

901797

CERS6
Ceramide synthase 6

1

2

High-throughput

0.489

High

901798

TBCD9
TBC1 domain family member 9

1

3

High-throughput

0.489

High

901808

PHTF2
Protein PHTF2

1

1

High-throughput

0.489

High

901821

CXD4
Gap junction delta-4 protein

1

9

High-throughput

0.489

High

901772

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

3

Small-scale

0.481

High

377219

GCR
Glucocorticoid receptor

1

4

High-throughput

0.479

High

384595

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.479

High

498242

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

1

1

High-throughput

0.479

High

552407

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.479

High

650855

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.479

High

793254

MUC18
Cell surface glycoprotein MUC18

1

1

High-throughput

0.479

High

882211

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

3

High-throughput

0.479

High

901768

1433E
14-3-3 protein epsilon

1

1

High-throughput

0.479

High

901770

TBA4A
Tubulin alpha-4A chain

1

1

Small-scale

0.479

High

901771

CDK5
Cyclin-dependent kinase 5

1

2

Small-scale

0.479

High

901777

TP4A2
Protein tyrosine phosphatase type IVA 2

1

1

Small-scale

0.479

High

901779

TIF1B
Transcription intermediary factor 1-beta

1

5

High-throughput

0.479

High

901789

KIF14
Kinesin-like protein KIF14

1

7

High-throughput

0.479

High

901799

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.479

High

901813

PREX1
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein

1

2

Small-scale

0.479

High

901827

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

2

Small-scale

0.479

High

901785

TBB2A
Tubulin beta-2A chain

1

0

Small-scale

0.458

High

901787

RBM39
RNA-binding protein 39

1

0

High-throughput

0.458

High

131227

BIN1
Myc box-dependent-interacting protein 1

1

4

High-throughput

0.457

High

164595

SPTN2
Spectrin beta chain, non-erythrocytic 2

1

3

High-throughput

0.457

High

224709

KALRN
Kalirin

1

4

High-throughput

0.457

High

231082

OPA1
Dynamin-like GTPase OPA1, mitochondrial

1

1

High-throughput

0.457

High

521517

ACTN1
Alpha-actinin-1

1

2

High-throughput

0.457

High

901769

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.457

High

901774

DYST
Dystonin

1

5

High-throughput

0.457

High

901800

TCPR1
Tectonin beta-propeller repeat-containing protein 1

1

1

High-throughput

0.457

High

901823

ABCA3
Phospholipid-transporting ATPase ABCA3

1

1

High-throughput

0.457

High

901826

SH3G1
Endophilin-A2

1

2

High-throughput

0.457

High

901831

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

1

1

High-throughput

0.457

High

901837

ARHGC
Rho guanine nucleotide exchange factor 12

1

3

High-throughput

0.457

High

239897

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

1

High-throughput

0.445

High

438046

HS90B
Heat shock protein HSP 90-beta

1

5

High-throughput

0.445

High

893266

SNP25
Synaptosomal-associated protein 25

1

11

Small-scale

0.445

High

901822

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

1

High-throughput

0.445

High

901842

ITM2B
Integral membrane protein 2B

1

1

High-throughput

0.445

High

242692

IF2P
Eukaryotic translation initiation factor 5B

1

0

High-throughput

0.438

High

825805

NASP
Nuclear autoantigenic sperm protein

1

0

High-throughput

0.438

High

854085

GDS1
Rap1 GTPase-GDP dissociation stimulator 1

1

0

High-throughput

0.438

High

901802

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

0

High-throughput

0.438

High

901804

KCMB4
Calcium-activated potassium channel subunit beta-4

1

0

High-throughput

0.438

High

901811

CEP70
Centrosomal protein of 70 kDa

1

0

High-throughput

0.438

High

901817

MY18A
Unconventional myosin-XVIIIa

1

0

High-throughput

0.438

High

901828

PARVB
Beta-parvin

1

0

High-throughput

0.438

High

901829

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

901835

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.438

High

901838

PARP2
Poly [ADP-ribose] polymerase 2

1

0

High-throughput

0.438

High

901781

PLD1
Phospholipase D1

1

0

Small-scale

0.433

High

834258

PSN1
Presenilin-1

1

0

Small-scale

0.426

High

901786

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.426

High

901815

NICA
Nicastrin

1

0

Small-scale

0.426

High

901803

SESD1
SEC14 domain and spectrin repeat-containing protein 1

1

4

High-throughput

0.417

High

901807

AN36B
Ankyrin repeat domain-containing protein 36B

1

3

High-throughput

0.417

High

901819

T4S18
Transmembrane 4 L6 family member 18

2

0

High-throughput

0.328

High

901775

BRME1
Break repair meiotic recombinase recruitment factor 1

1

0

High-throughput

0.299

High

883090

DSCR6
Protein ripply3

1

0

High-throughput

0.282

High

901830

TM140
Transmembrane protein 140

1

0

High-throughput

0.269

Low

901795

OBI1
ORC ubiquitin ligase 1

1

0

High-throughput

0.238

Low

901810

CC148
Coiled-coil domain-containing protein 148

1

0

High-throughput

0.238

Low

901841

NP1L2
Nucleosome assembly protein 1-like 2

1

0

High-throughput

0.238

Low

901792

WHAL1
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024