Protein: DPYL2
Dihydropyrimidinase-related protein 2 (DRP-2) (Collapsin response mediator protein 2) (CRMP-2) (N2A3) (Unc-33-like phosphoprotein 2) (ULIP-2)

Gene: DPYL2, DPYSL2
Organism: Homo sapiens
Interactions: 121
UniProt ID: Q16555

Gene Ontology (top 5):
GO:0004157 - dihydropyrimidinase activity
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0005886 - plasma membrane
GO:0006139 - nucleobase-containing compound metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1050916

DPYL3
Dihydropyrimidinase-related protein 3

9

17

High-throughput

0.976

High

1083135

DPYL5
Dihydropyrimidinase-related protein 5

7

18

High-throughput

0.971

High

1083101

DPYL2
Dihydropyrimidinase-related protein 2

6

18

High-throughput

0.942

High

1050867

DPYL1
Dihydropyrimidinase-related protein 1

5

18

Small-scale

0.925

High

1048473

DPYS
Dihydropyrimidinase

2

16

High-throughput

0.811

High

147335

DPYL4
Dihydropyrimidinase-related protein 4

2

17

High-throughput

0.806

High

1083144

GORS2
Golgi reassembly-stacking protein 2

5

1

High-throughput

0.722

High

1083150

KTU
Protein kintoun

3

5

High-throughput

0.667

High

814960

LEG7
Galectin-7

2

3

High-throughput

0.611

High

1083102

DGUOK
Deoxyguanosine kinase, mitochondrial

2

4

High-throughput

0.611

High

1083136

KLDC3
Kelch domain-containing protein 3

2

5

High-throughput

0.611

High

1083151

ARMC1
Armadillo repeat-containing protein 1

2

3

High-throughput

0.611

High

118325

HAX1
HCLS1-associated protein X-1

3

5

High-throughput

0.609

High

1083137

WDR83
WD repeat domain-containing protein 83

3

4

High-throughput

0.609

High

1083155

NUFP1
FMR1-interacting protein NUFIP1

3

4

High-throughput

0.609

High

779496

CCNF
Cyclin-F

2

3

High-throughput

0.601

High

1083118

Q8IXW6
Dihydropyrimidinase-like 3

1

18

High-throughput

0.594

High

1083149

DISC1
Disrupted in schizophrenia 1 protein

2

2

High-throughput

0.590

High

791594

HD
Huntingtin

2

6

High-throughput

0.588

High

227582

PRKN
E3 ubiquitin-protein ligase parkin

2

6

High-throughput

0.584

High

1043826

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

2

8

High-throughput

0.584

High

1083158

TNIK
TRAF2 and NCK-interacting protein kinase

2

6

High-throughput

0.576

High

1083113

TAFA3
Chemokine-like protein TAFA-3

2

1

High-throughput

0.574

High

504144

HSP7C
Heat shock cognate 71 kDa protein

2

4

High-throughput

0.571

High

833602

NUMB
Protein numb homolog

1

2

Small-scale

0.561

High

321555

AP2A1
AP-2 complex subunit alpha-1

1

0

Small-scale

0.537

High

497102

TAU
Microtubule-associated protein tau

1

9

High-throughput

0.536

High

506592

BCR
Breakpoint cluster region protein

1

6

High-throughput

0.536

High

849547

GPM6A
Neuronal membrane glycoprotein M6-a

1

4

High-throughput

0.536

High

1065925

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

3

High-throughput

0.536

High

1083107

SPSB3
SPRY domain-containing SOCS box protein 3

1

9

High-throughput

0.536

High

1083138

TX101
Testis-expressed protein 101

1

1

High-throughput

0.536

High

1083157

CDC23
Cell division cycle protein 23 homolog

1

1

High-throughput

0.536

High

1083161

X5DQV1
Collapsin response mediator protein 1 isoform B

1

18

High-throughput

0.528

High

234523

DSCAM
Cell adhesion molecule DSCAM

1

0

High-throughput

0.518

High

670793

BLVRB
Flavin reductase

1

0

High-throughput

0.513

High

862293

NUBP1
Cytosolic Fe-S cluster assembly factor NUBP1

1

0

High-throughput

0.513

High

894057

CDC42
Cell division control protein 42 homolog

1

3

High-throughput

0.501

High

930240

UBC9
SUMO-conjugating enzyme UBC9

1

3

Small-scale

0.501

High

1083122

ARI1B
AT-rich interactive domain-containing protein 1B

1

2

High-throughput

0.500

High

1083139

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

8

High-throughput

0.500

High

1083156

LEF1
Lymphoid enhancer-binding factor 1

1

2

High-throughput

0.494

High

1083117

TF2LY
Homeobox protein TGIF2LY

1

1

High-throughput

0.489

High

1083126

NEK7
Serine/threonine-protein kinase Nek7

1

2

High-throughput

0.489

High

1083133

MMAB
Corrinoid adenosyltransferase MMAB

1

2

High-throughput

0.489

High

1063720

EXOS7
Exosome complex component RRP42

1

3

High-throughput

0.481

High

125490

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

8

High-throughput

0.479

High

205441

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.479

High

322694

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.479

High

384912

NTRK1
High affinity nerve growth factor receptor

1

10

High-throughput

0.479

High

428235

TBB5
Tubulin beta chain

1

7

High-throughput

0.479

High

610419

CBL
E3 ubiquitin-protein ligase CBL

1

4

High-throughput

0.479

High

625465

CDK2
Cyclin-dependent kinase 2

1

3

High-throughput

0.479

High

685696

PRDX2
Peroxiredoxin-2

1

3

Small-scale

0.479

High

737826

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

3

Small-scale

0.479

High

808651

YAP1
Transcriptional coactivator YAP1

1

10

High-throughput

0.479

High

835789

GSK3B
Glycogen synthase kinase-3 beta

1

4

Small-scale

0.479

High

874981

TERA
Transitional endoplasmic reticulum ATPase

1

7

High-throughput

0.479

High

905929

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

2

Small-scale

0.479

High

908616

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

5

High-throughput

0.479

High

980264

K1C17
Keratin, type I cytoskeletal 17

1

2

High-throughput

0.479

High

1028141

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

7

Small-scale

0.479

High

1030266

G3BP1
Ras GTPase-activating protein-binding protein 1

1

4

High-throughput

0.479

High

1041671

CUL3
Cullin-3

1

3

High-throughput

0.479

High

1071885

PCBP1
Poly(rC)-binding protein 1

1

1

Small-scale

0.479

High

1083103

BOREA
Borealin

1

2

High-throughput

0.479

High

1083105

RN123
E3 ubiquitin-protein ligase RNF123

1

1

High-throughput

0.479

High

1083106

VIR
Protein virilizer homolog

1

1

High-throughput

0.479

High

1083108

RICTR
Rapamycin-insensitive companion of mTOR

1

1

High-throughput

0.479

High

1083109

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

7

High-throughput

0.479

High

1083110

TRI67
Tripartite motif-containing protein 67

1

9

High-throughput

0.479

High

1083111

TBA1A
Tubulin alpha-1A chain

1

13

High-throughput

0.479

High

1083114

MARH3
E3 ubiquitin-protein ligase MARCHF3

1

1

High-throughput

0.479

High

1083115

NAA40
N-alpha-acetyltransferase 40

1

2

High-throughput

0.479

High

1083120

NIN
Ninein

1

1

High-throughput

0.479

High

1083121

NHLC2
NHL repeat-containing protein 2

1

1

High-throughput

0.479

High

1083124

PREX1
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein

1

2

Small-scale

0.479

High

1083125

BICD2
Protein bicaudal D homolog 2

1

5

High-throughput

0.479

High

1083128

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

1083131

ARMC5
Armadillo repeat-containing protein 5

1

2

High-throughput

0.479

High

1083132

SPDLY
Protein Spindly

1

4

High-throughput

0.479

High

1083142

RGAP1
Rac GTPase-activating protein 1

1

3

High-throughput

0.479

High

1083143

PKHA4
Pleckstrin homology domain-containing family A member 4

1

8

High-throughput

0.479

High

1083147

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

1

High-throughput

0.479

High

1083153

MARH2
E3 ubiquitin-protein ligase MARCHF2

1

1

High-throughput

0.479

High

1083154

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

1083159

BAG5
BAG family molecular chaperone regulator 5

1

1

High-throughput

0.479

High

305855

UBL3
Ubiquitin-like protein 3

1

0

Small-scale

0.458

High

1083119

MILK1
MICAL-like protein 1

1

0

Small-scale

0.458

High

1083127

NUDC2
NudC domain-containing protein 2

1

0

High-throughput

0.458

High

1083130

OTUL
Ubiquitin thioesterase otulin

1

0

Small-scale

0.458

High

1083141

TOLIP
Toll-interacting protein

1

0

High-throughput

0.458

High

1083145

NGB
Neuroglobin

1

0

High-throughput

0.458

High

1083152

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1057481

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

2

Small-scale

0.445

High

1083140

ZDHC5
Palmitoyltransferase ZDHHC5

1

1

High-throughput

0.445

High

244503

BRD4
Bromodomain-containing protein 4

1

2

High-throughput

0.437

High

346900

MYC
Myc proto-oncogene protein

1

4

High-throughput

0.437

High

552837

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.437

High

569784

CEBPB
CCAAT/enhancer-binding protein beta

1

2

High-throughput

0.437

High

651323

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.437

High

720575

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

832493

MCM2
DNA replication licensing factor MCM2

1

4

High-throughput

0.437

High

903256

WDR5
WD repeat-containing protein 5

1

5

High-throughput

0.437

High

1026428

RFA4
Replication protein A 30 kDa subunit

1

4

High-throughput

0.437

High

1043015

CUL4A
Cullin-4A

1

3

High-throughput

0.437

High

1079985

EZH2
Histone-lysine N-methyltransferase EZH2

1

4

High-throughput

0.437

High

1083112

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.437

High

1083116

MGDP1
Magnesium-dependent phosphatase 1

1

2

High-throughput

0.437

High

1083129

HDAC2
Histone deacetylase 2

1

5

High-throughput

0.437

High

1083148

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

3

High-throughput

0.437

High

1083160

RRP7A
Ribosomal RNA-processing protein 7 homolog A

1

2

High-throughput

0.437

High

1083123

STT3B
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B

1

0

High-throughput

0.279

Low

1083146

LUC7L
Putative RNA-binding protein Luc7-like 1

1

0

High-throughput

0.251

Low

964345

RUNX1
Runt-related transcription factor 1

1

0

High-throughput

0.249

Low

1049049

TRI14
Tripartite motif-containing protein 14

1

0

High-throughput

0.249

Low

1081272

E2F4
Transcription factor E2F4

1

0

High-throughput

0.249

Low

1083104

TET5C
Terminal nucleotidyltransferase 5C

1

0

High-throughput

0.249

Low

1083134

CGRF1
Cell growth regulator with RING finger domain protein 1

1

0

High-throughput

0.249

Low

886286

DSCR9
Down syndrome critical region protein 9

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024