Protein: NDKA
Nucleoside diphosphate kinase A (NDK A) (NDP kinase A) (EC 2.7.4.6) (Granzyme A-activated DNase) (GAAD) (Metastasis inhibition factor nm23) (NM23-H1) (Tumor metastatic process-associated protein)

Gene: NDKA, NME1
Organism: Homo sapiens
Interactions: 163
UniProt ID: P15531

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0003723 - RNA binding
GO:0004536 - DNA nuclease activity
GO:0004550 - nucleoside diphosphate kinase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

548853

NDKA
Nucleoside diphosphate kinase A

12

16

Small-scale

0.983

High

548860

NDKB
Nucleoside diphosphate kinase B

7

17

Small-scale

0.957

High

548904

NDK3
Nucleoside diphosphate kinase 3

6

17

Small-scale

0.954

High

135572

NDKM
Nucleoside diphosphate kinase, mitochondrial

6

17

High-throughput

0.954

High

169782

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

6

1

High-throughput

0.736

High

233736

NDK8
Putative nucleoside diphosphate kinase

2

16

High-throughput

0.712

High

548941

NTAQ1
Protein N-terminal glutamine amidohydrolase

5

0

High-throughput

0.689

High

548884

FXR2
RNA-binding protein FXR2

3

4

High-throughput

0.672

High

548893

NTF2
Nuclear transport factor 2

2

3

High-throughput

0.606

High

548933

LNX1
E3 ubiquitin-protein ligase LNX

2

2

High-throughput

0.606

High

548971

TNPO3
Transportin-3

2

2

High-throughput

0.606

High

548887

TERF1
Telomeric repeat-binding factor 1

2

1

Small-scale

0.601

High

548970

STRAP
Serine-threonine kinase receptor-associated protein

1

1

Small-scale

0.600

High

548892

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

2

1

Small-scale

0.595

High

226430

PRKN
E3 ubiquitin-protein ligase parkin

2

8

High-throughput

0.584

High

345837

MYC
Myc proto-oncogene protein

2

2

Small-scale

0.584

High

548912

Q32Q12
Nucleoside diphosphate kinase

1

16

High-throughput

0.575

High

155521

TNPO2
Transportin-2

1

2

High-throughput

0.573

High

416562

S10A6
Protein S100-A6

2

2

High-throughput

0.571

High

428002

TBB5
Tubulin beta chain

2

6

High-throughput

0.571

High

437863

HS90B
Heat shock protein HSP 90-beta

2

1

High-throughput

0.571

High

499509

CH60
60 kDa heat shock protein, mitochondrial

2

6

High-throughput

0.571

High

501638

BIP
Endoplasmic reticulum chaperone BiP

2

6

High-throughput

0.571

High

503373

HSP7C
Heat shock cognate 71 kDa protein

2

3

High-throughput

0.571

High

518572

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

2

2

High-throughput

0.571

High

531023

EF2
Elongation factor 2

2

5

High-throughput

0.571

High

548854

DESP
Desmoplakin

2

3

High-throughput

0.571

High

548857

TCPA
T-complex protein 1 subunit alpha

2

3

High-throughput

0.571

High

548862

SYVC
Valine--tRNA ligase

2

3

High-throughput

0.571

High

548863

1433T
14-3-3 protein theta

2

5

High-throughput

0.571

High

548864

PTN6
Tyrosine-protein phosphatase non-receptor type 6

2

1

High-throughput

0.571

High

548865

PRDX6
Peroxiredoxin-6

2

3

High-throughput

0.571

High

548870

GRP75
Stress-70 protein, mitochondrial

2

9

High-throughput

0.571

High

548871

TCPZ
T-complex protein 1 subunit zeta

2

3

High-throughput

0.571

High

548872

SYIC
Isoleucine--tRNA ligase, cytoplasmic

2

1

High-throughput

0.571

High

548875

TCPE
T-complex protein 1 subunit epsilon

2

4

High-throughput

0.571

High

548876

FAS
Fatty acid synthase

2

2

High-throughput

0.571

High

548877

TCPG
T-complex protein 1 subunit gamma

2

4

High-throughput

0.571

High

548881

TCPQ
T-complex protein 1 subunit theta

2

5

High-throughput

0.571

High

548882

TCPD
T-complex protein 1 subunit delta

2

3

High-throughput

0.571

High

548896

1433Z
14-3-3 protein zeta/delta

2

5

High-throughput

0.571

High

548897

TCPB
T-complex protein 1 subunit beta

2

4

High-throughput

0.571

High

548902

PRDX1
Peroxiredoxin-1

2

3

High-throughput

0.571

High

548905

TIF1B
Transcription intermediary factor 1-beta

2

1

High-throughput

0.571

High

548915

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

4

High-throughput

0.571

High

548918

RBP10
Ran-binding protein 10

2

5

High-throughput

0.571

High

548946

TCPH
T-complex protein 1 subunit eta

2

4

High-throughput

0.571

High

548961

GID8
Glucose-induced degradation protein 8 homolog

2

4

High-throughput

0.571

High

548968

RUVB1
RuvB-like 1

2

2

High-throughput

0.571

High

500927

MCF2
Proto-oncogene DBL

1

3

Small-scale

0.562

High

535784

MIF
Macrophage migration inhibitory factor

1

1

Small-scale

0.561

High

548952

NIF3L
NIF3-like protein 1

1

1

High-throughput

0.560

High

160359

AURKA
Aurora kinase A

1

3

Small-scale

0.552

High

403766

ITB1
Integrin beta-1

1

2

Small-scale

0.552

High

548924

PRUN1
Exopolyphosphatase PRUNE1

1

0

Small-scale

0.549

High

329316

AGR2
Anterior gradient protein 2 homolog

2

1

Small-scale

0.549

High

548923

PCLI1
PTB-containing, cubilin and LRP1-interacting protein

1

0

High-throughput

0.549

High

388204

HSPB1
Heat shock protein beta-1

2

0

High-throughput

0.547

High

548885

SYRC
Arginine--tRNA ligase, cytoplasmic

2

0

High-throughput

0.547

High

548899

DSG1
Desmoglein-1

2

0

High-throughput

0.547

High

548883

FXR1
RNA-binding protein FXR1

1

4

High-throughput

0.541

High

128427

DNM1L
Dynamin-1-like protein

1

5

High-throughput

0.536

High

548927

FOXP4
Forkhead box protein P4

1

1

High-throughput

0.536

High

303574

SOX30
Transcription factor SOX-30

1

0

High-throughput

0.518

High

548956

GORS2
Golgi reassembly-stacking protein 2

1

0

High-throughput

0.518

High

548966

UBP18
Ubl carboxyl-terminal hydrolase 18

1

1

High-throughput

0.515

High

528481

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.513

High

548868

SOAT1
Sterol O-acyltransferase 1

1

0

High-throughput

0.513

High

548909

FL2D
Pre-mRNA-splicing regulator WTAP

1

0

High-throughput

0.513

High

548932

RIN3
Ras and Rab interactor 3

1

0

High-throughput

0.513

High

548955

SMYD3
Histone-lysine N-methyltransferase SMYD3

1

0

High-throughput

0.513

High

548895

RAC1
Ras-related C3 botulinum toxin substrate 1

1

2

Small-scale

0.501

High

548879

DYN2
Dynamin-2

1

5

Small-scale

0.500

High

548948

KLF16
Krueppel-like factor 16

1

2

High-throughput

0.500

High

548866

CCND3
G1/S-specific cyclin-D3

1

1

High-throughput

0.481

High

548964

NXF1
Nuclear RNA export factor 1

1

1

High-throughput

0.481

High

118534

EYA2
Eyes absent homolog 2

1

1

High-throughput

0.479

High

128014

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

1

1

High-throughput

0.479

High

165923

PER2
Period circadian protein homolog 2

1

1

Small-scale

0.479

High

294332

RECQ4
ATP-dependent DNA helicase Q4

1

2

High-throughput

0.479

High

301595

TRI37
E3 ubiquitin-protein ligase TRIM37

1

5

High-throughput

0.479

High

373634

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

6

High-throughput

0.479

High

378982

MYCN
N-myc proto-oncogene protein

1

2

High-throughput

0.479

High

450701

F16P1
Fructose-1,6-bisphosphatase 1

1

1

High-throughput

0.479

High

488558

ARAF
Serine/threonine-protein kinase A-Raf

1

6

High-throughput

0.479

High

548856

CEBPB
CCAAT/enhancer-binding protein beta

1

3

High-throughput

0.479

High

548858

EGR1
Early growth response protein 1

1

2

High-throughput

0.479

High

548861

TBG1
Tubulin gamma-1 chain

1

8

High-throughput

0.479

High

548867

BMI1
Polycomb complex protein BMI-1

1

2

High-throughput

0.479

High

548869

BRCA1
Breast cancer type 1 susceptibility protein

1

1

High-throughput

0.479

High

548874

TISD
mRNA decay activator protein ZFP36L2

1

1

High-throughput

0.479

High

548878

MCM2
DNA replication licensing factor MCM2

1

1

High-throughput

0.479

High

548880

PPT1
Palmitoyl-protein thioesterase 1

1

1

High-throughput

0.479

High

548890

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.479

High

548894

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.479

High

548898

SET
Protein SET

1

2

Small-scale

0.479

High

548900

DYN1
Dynamin-1

1

5

Small-scale

0.479

High

548901

DUS2
Dual specificity protein phosphatase 2

1

6

High-throughput

0.479

High

548903

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

3

Small-scale

0.479

High

548907

RBM39
RNA-binding protein 39

1

1

High-throughput

0.479

High

548908

EMC2
ER membrane protein complex subunit 2

1

1

High-throughput

0.479

High

548910

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

4

High-throughput

0.479

High

548911

CL16A
Protein CLEC16A

1

1

High-throughput

0.479

High

548920

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.479

High

548921

ASB18
Ankyrin repeat and SOCS box protein 18

1

1

High-throughput

0.479

High

548925

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

548926

GOLI
E3 ubiquitin-protein ligase RNF130

1

3

High-throughput

0.479

High

548928

Z3H7A
Zinc finger CCCH domain-containing protein 7A

1

4

High-throughput

0.479

High

548929

SMC5
Structural maintenance of chromosomes protein 5

1

1

High-throughput

0.479

High

548931

NUP43
Nucleoporin Nup43

1

1

High-throughput

0.479

High

548934

DUS19
Dual specificity protein phosphatase 19

1

6

High-throughput

0.479

High

548936

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

548937

AKAP1
A-kinase anchor protein 1, mitochondrial

1

2

High-throughput

0.479

High

548939

CHM4C
Charged multivesicular body protein 4c

1

1

High-throughput

0.479

High

548943

RANB9
Ran-binding protein 9

1

6

Small-scale

0.479

High

548945

EYA3
Eyes absent homolog 3

1

1

High-throughput

0.479

High

548949

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

3

High-throughput

0.479

High

548950

FACD2
Fanconi anemia group D2 protein

1

1

High-throughput

0.479

High

548958

DUS22
Dual specificity protein phosphatase 22

1

6

High-throughput

0.479

High

548960

PIHD1
PIH1 domain-containing protein 1

1

1

High-throughput

0.479

High

548962

OCAD1
OCIA domain-containing protein 1

1

3

High-throughput

0.479

High

548965

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

548967

HDAC5
Histone deacetylase 5

1

4

High-throughput

0.479

High

300047

PRP6
Pre-mRNA-processing factor 6

1

0

High-throughput

0.460

High

548940

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

0

High-throughput

0.460

High

548959

DD19A
ATP-dependent RNA helicase DDX19A

1

0

High-throughput

0.460

High

119140

LEG9
Galectin-9

1

0

High-throughput

0.458

High

241957

PAGE4
P antigen family member 4

1

0

High-throughput

0.458

High

310492

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

0

Small-scale

0.458

High

507358

ERG
Transcriptional regulator ERG

1

0

Small-scale

0.458

High

542165

PLAK
Junction plakoglobin

1

0

High-throughput

0.458

High

548855

GATA1
Erythroid transcription factor

1

0

Small-scale

0.458

High

548873

MAP1B
Microtubule-associated protein 1B

1

0

High-throughput

0.458

High

548886

ATX3
Ataxin-3

1

0

High-throughput

0.458

High

548888

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

0

High-throughput

0.458

High

548889

RAD
GTP-binding protein RAD

1

0

Small-scale

0.458

High

548891

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.458

High

548906

CUL3
Cullin-3

1

0

High-throughput

0.458

High

548913

MIDN
Midnolin

1

0

High-throughput

0.458

High

548916

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

548917

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.458

High

548935

NALP7
NACHT, LRR and PYD domains-containing protein 7

1

0

High-throughput

0.458

High

548938

KAT2A
Histone acetyltransferase KAT2A

1

0

Small-scale

0.458

High

548944

KCD15
BTB/POZ domain-containing protein KCTD15

1

0

Small-scale

0.458

High

548947

BAG1
BAG family molecular chaperone regulator 1

1

0

High-throughput

0.458

High

548957

FBX6
F-box only protein 6

1

0

High-throughput

0.458

High

548963

MARH5
E3 ubiquitin-protein ligase MARCHF5

1

0

High-throughput

0.458

High

382292

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

1

High-throughput

0.445

High

496225

TAU
Microtubule-associated protein tau

1

3

High-throughput

0.445

High

548914

H90B3
Putative heat shock protein HSP 90-beta-3

1

1

High-throughput

0.445

High

548953

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

1

High-throughput

0.445

High

548954

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

1

High-throughput

0.445

High

205000

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.437

High

548922

ASXL2
Putative Polycomb group protein ASXL2

1

5

High-throughput

0.437

High

548951

ASXL3
Putative Polycomb group protein ASXL3

1

5

High-throughput

0.437

High

548969

AAR2
Protein AAR2 homolog

1

2

High-throughput

0.437

High

548859

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

0

Small-scale

0.426

High

548930

SR1IP
Protein SREK1IP1

1

0

High-throughput

0.299

High

548942

PGAM5
Serine/threonine-protein phosphatase PGAM5, mitochondrial

2

0

High-throughput

0.298

High

264474

FBX24
F-box only protein 24

1

0

Small-scale

0.292

High

225510

PCDH7
Protocadherin-7

1

0

High-throughput

0.249

Low

548919

TIFAB
TRAF-interacting protein with FHA domain-containing protein B

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024