Protein: DCA11
DDB1- and CUL4-associated factor 11 (WD repeat-containing protein 23)

Gene: DCA11, DCAF11
Organism: Homo sapiens
Interactions: 128
UniProt ID: Q8TEB1

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0016567 - protein ubiquitination
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0080008 - Cul4-RING E3 ubiquitin ligase complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1082295

DDB1
DNA damage-binding protein 1

15

20

Small-scale

0.984

High

1043117

CUL4A
Cullin-4A

14

20

Small-scale

0.761

High

1043471

CUL4B
Cullin-4B

9

20

Small-scale

0.754

High

1184916

CSN6
COP9 signalosome complex subunit 6

8

1

Small-scale

0.750

High

1255935

CSN5
COP9 signalosome complex subunit 5

6

8

Small-scale

0.729

High

1255950

DDA1
DET1- and DDB1-associated protein 1

5

3

Small-scale

0.718

High

1255960

CSN7A
COP9 signalosome complex subunit 7a

5

2

High-throughput

0.718

High

897277

CSN2
COP9 signalosome complex subunit 2

4

5

High-throughput

0.694

High

1255949

CSN4
COP9 signalosome complex subunit 4

4

1

High-throughput

0.694

High

1255965

CSN3
COP9 signalosome complex subunit 3

4

4

High-throughput

0.694

High

1255963

APC4
Anaphase-promoting complex subunit 4

1

1

High-throughput

0.691

High

843304

TCPD
T-complex protein 1 subunit delta

3

20

High-throughput

0.667

High

1255954

CSN7B
COP9 signalosome complex subunit 7b

3

2

High-throughput

0.667

High

1054262

SLBP
Histone RNA hairpin-binding protein

2

1

Small-scale

0.653

High

1255945

CSN8
COP9 signalosome complex subunit 8

3

0

High-throughput

0.646

High

861859

PLK1
Serine/threonine-protein kinase PLK1

2

7

High-throughput

0.628

High

1024190

CSN1
COP9 signalosome complex subunit 1

2

4

High-throughput

0.628

High

1081233

NF2L2
Nuclear factor erythroid 2-related factor 2

2

10

Small-scale

0.624

High

658270

5HT2C
5-hydroxytryptamine receptor 2C

1

1

High-throughput

0.618

High

896157

UBC12
NEDD8-conjugating enzyme Ubc12

1

6

High-throughput

0.618

High

929582

RACK1
Small ribosomal subunit protein RACK1

1

18

High-throughput

0.618

High

1246124

COP1
E3 ubiquitin-protein ligase COP1

1

18

High-throughput

0.618

High

1255952

PDCL3
Phosducin-like protein 3

1

4

High-throughput

0.618

High

1255964

NOB1
RNA-binding protein NOB1

1

1

High-throughput

0.618

High

1255937

CUL5
Cullin-5

2

20

High-throughput

0.611

High

573390

TCPA
T-complex protein 1 subunit alpha

3

20

High-throughput

0.609

High

770950

TCPZ
T-complex protein 1 subunit zeta

3

20

High-throughput

0.609

High

821330

TCPE
T-complex protein 1 subunit epsilon

3

20

High-throughput

0.609

High

826792

TCPG
T-complex protein 1 subunit gamma

3

20

High-throughput

0.609

High

943376

TCPB
T-complex protein 1 subunit beta

3

20

High-throughput

0.609

High

1255947

TCPH
T-complex protein 1 subunit eta

3

20

High-throughput

0.609

High

921355

RBX1
E3 ubiquitin-protein ligase RBX1

2

2

Small-scale

0.584

High

506013

ODB2
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

2

2

High-throughput

0.574

High

1223658

MICU2
Calcium uptake protein 2, mitochondrial

2

2

High-throughput

0.574

High

1255932

TCPW
T-complex protein 1 subunit zeta-2

2

20

High-throughput

0.574

High

758291

CDN1A
Cyclin-dependent kinase inhibitor 1

1

1

Small-scale

0.573

High

581196

TNNI1
Troponin I, slow skeletal muscle

2

1

High-throughput

0.553

High

822807

TNNI2
Troponin I, fast skeletal muscle

2

1

High-throughput

0.553

High

1205868

GPSM1
G-protein-signaling modulator 1

2

14

High-throughput

0.553

High

1170953

TRI67
Tripartite motif-containing protein 67

1

14

High-throughput

0.553

High

1255951

TRI55
Tripartite motif-containing protein 55

1

20

High-throughput

0.541

High

1079549

NEDD8
NEDD8

1

2

High-throughput

0.536

High

1144592

TENS2
Tensin-2

2

4

High-throughput

0.526

High

1255955

ELP3
Elongator complex protein 3

1

0

High-throughput

0.517

High

1255957

PAR11
Protein mono-ADP-ribosyltransferase PARP11

1

6

High-throughput

0.515

High

471627

TFPT
TCF3 fusion partner

1

0

High-throughput

0.513

High

1255931

CSN9
COP9 signalosome complex subunit 9

1

0

High-throughput

0.513

High

1255953

PIF1
ATP-dependent DNA helicase PIF1

1

0

High-throughput

0.513

High

1255961

FXL17
F-box/LRR-repeat protein 17

1

0

High-throughput

0.513

High

923832

FKB1A
Peptidyl-prolyl cis-trans isomerase FKBP1A

1

4

Small-scale

0.512

High

358840

CRYAA
Alpha-crystallin A chain

1

4

High-throughput

0.501

High

890762

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

3

Small-scale

0.501

High

1229742

ZN444
Zinc finger protein 444

1

1

High-throughput

0.489

High

1255948

MICU1
Calcium uptake protein 1, mitochondrial

1

2

High-throughput

0.489

High

1255956

MAGE1
Melanoma-associated antigen E1

1

5

High-throughput

0.489

High

1255959

TBCC1
TBCC domain-containing protein 1

1

1

High-throughput

0.489

High

1255938

TRI63
E3 ubiquitin-protein ligase TRIM63

1

13

High-throughput

0.481

High

118583

EYA2
Eyes absent homolog 2

1

8

High-throughput

0.479

High

118765

AIP
AH receptor-interacting protein

1

7

High-throughput

0.479

High

121820

PSD11
26S proteasome non-ATPase regulatory subunit 11

1

5

High-throughput

0.479

High

228153

PRKN
E3 ubiquitin-protein ligase parkin

1

15

High-throughput

0.479

High

323435

TTC4
Tetratricopeptide repeat protein 4

1

14

High-throughput

0.479

High

625521

CDK2
Cyclin-dependent kinase 2

1

4

Small-scale

0.479

High

667764

NOS1
Nitric oxide synthase 1

1

1

High-throughput

0.479

High

779786

CCNF
Cyclin-F

1

6

High-throughput

0.479

High

830184

PRI2
DNA primase large subunit

1

1

High-throughput

0.479

High

1023207

FLII
Protein flightless-1 homolog

1

2

High-throughput

0.479

High

1032522

CTBP1
C-terminal-binding protein 1

1

7

Small-scale

0.479

High

1042119

CUL3
Cullin-3

1

20

High-throughput

0.479

High

1049280

KEAP1
Kelch-like ECH-associated protein 1

1

2

High-throughput

0.479

High

1072393

ELOB
Elongin-B

1

1

High-throughput

0.479

High

1232178

ASCC3
Activating signal cointegrator 1 complex subunit 3

1

14

High-throughput

0.479

High

1255942

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

3

Small-scale

0.479

High

1255944

NUP88
Nuclear pore complex protein Nup88

1

1

High-throughput

0.479

High

1255958

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

5

Small-scale

0.479

High

1255962

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.479

High

1255966

RUVB2
RuvB-like 2

1

4

High-throughput

0.479

High

1255967

NUDC
Nuclear migration protein nudC

1

13

High-throughput

0.479

High

1255968

DRG1
Developmentally-regulated GTP-binding protein 1

1

5

High-throughput

0.479

High

1255971

RTCB
RNA-splicing ligase RtcB homolog

1

1

High-throughput

0.479

High

1022656

AF1Q
Protein AF1q

1

0

High-throughput

0.458

High

1047450

PEBB
Core-binding factor subunit beta

1

0

High-throughput

0.458

High

1255940

DCNL1
DCN1-like protein 1

1

0

High-throughput

0.458

High

517381

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.438

High

171658

PFD6
Prefoldin subunit 6

1

6

High-throughput

0.437

High

180386

MAGB2
Melanoma-associated antigen B2

1

5

High-throughput

0.437

High

234254

PEPL
Periplakin

1

16

High-throughput

0.437

High

422067

LDHB
L-lactate dehydrogenase B chain

1

1

High-throughput

0.437

High

533497

ETFA
Electron transfer flavoprotein subunit alpha, mitochondrial

1

2

High-throughput

0.437

High

551785

DESP
Desmoplakin

1

15

High-throughput

0.437

High

598244

FLNA
Filamin-A

1

10

High-throughput

0.437

High

674959

PUR8
Adenylosuccinate lyase

1

1

High-throughput

0.437

High

839960

F10A1
Hsc70-interacting protein

1

10

High-throughput

0.437

High

848910

AL3A2
Aldehyde dehydrogenase family 3 member A2

1

3

High-throughput

0.437

High

901711

PFD3
Prefoldin subunit 3

1

6

High-throughput

0.437

High

960897

CLH1
Clathrin heavy chain 1

1

4

High-throughput

0.437

High

1159062

CEP85
Centrosomal protein of 85 kDa

1

18

High-throughput

0.437

High

1173693

VP13C
Intermembrane lipid transfer protein VPS13C

1

1

High-throughput

0.437

High

1189138

CC186
Coiled-coil domain-containing protein 186

1

7

High-throughput

0.437

High

1253186

TBC15
TBC1 domain family member 15

1

2

High-throughput

0.437

High

1255929

PP4R1
Serine/threonine-protein phosphatase 4 regulatory subunit 1

1

4

High-throughput

0.437

High

1255933

LPIN2
Phosphatidate phosphatase LPIN2

1

3

High-throughput

0.437

High

1255936

GLMN
Glomulin

1

1

High-throughput

0.437

High

1255939

GCP3
Gamma-tubulin complex component 3

1

1

High-throughput

0.437

High

1255943

PFD5
Prefoldin subunit 5

1

7

High-throughput

0.437

High

1255972

GRIP1
Glutamate receptor-interacting protein 1

1

3

High-throughput

0.437

High

172596

GNPAT
Dihydroxyacetone phosphate acyltransferase

2

0

High-throughput

0.328

High

1082526

2A5E
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform

2

0

High-throughput

0.328

High

1233310

PNKD
Probable hydrolase PNKD

2

0

High-throughput

0.318

High

329853

AGR2
Anterior gradient protein 2 homolog

2

0

High-throughput

0.316

High

1070874

RCN1
Reticulocalbin-1

2

0

High-throughput

0.316

High

389481

REL1
Prorelaxin H1 [Cleaved into: Relaxin B chain; Relaxin A chain]

1

0

High-throughput

0.279

Low

1152909

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.279

Low

1224049

TRM2A
tRNA

1

0

High-throughput

0.279

Low

1255969

B3GN3
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3

1

0

High-throughput

0.279

Low

1255970

GSTK1
Glutathione S-transferase kappa 1

1

0

High-throughput

0.279

Low

166443

PUR4
Phosphoribosylformylglycinamidine synthase

1

0

High-throughput

0.249

Low

325288

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

0

Small-scale

0.249

Low

864093

AP2S1
AP-2 complex subunit sigma

1

0

High-throughput

0.249

Low

953164

CCZ1B
Vacuolar fusion protein CCZ1 homolog B

1

0

High-throughput

0.249

Low

1047970

COTL1
Coactosin-like protein

1

0

High-throughput

0.249

Low

1137696

STRP1
Striatin-interacting protein 1

1

0

High-throughput

0.249

Low

1199595

LBN
Limbin

1

0

High-throughput

0.249

Low

1255930

OSCP1
Protein OSCP1

1

0

High-throughput

0.249

Low

1255934

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

0

High-throughput

0.249

Low

1255941

CDRTF
CMT1A duplicated region transcript 15 protein

1

0

High-throughput

0.249

Low

1255946

METH
Methionine synthase

1

0

High-throughput

0.249

Low

1255973

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024