Protein: FGR
Tyrosine-protein kinase Fgr (EC 2.7.10.2) (Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog) (Proto-oncogene c-Fgr) (p55-Fgr) (p58-Fgr) (p58c-Fgr)

Gene: FGR
Organism: Homo sapiens
Interactions: 85
UniProt ID: P09769

Gene Ontology (top 5):
GO:0001784 - phosphotyrosine residue binding
GO:0001819 - positive regulation of cytokine production
GO:0002768 - immune response-regulating cell surface receptor signaling pathway
GO:0002862 - negative regulation of inflammatory response to antigenic stimulus
GO:0004713 - protein tyrosine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

433222

YES
Tyrosine-protein kinase Yes

4

19

High-throughput

0.892

High

433535

LYN
Tyrosine-protein kinase Lyn

4

19

High-throughput

0.881

High

337821

EGFR
Epidermal growth factor receptor

3

20

High-throughput

0.867

High

300622

CDK14
Cyclin-dependent kinase 14

2

14

High-throughput

0.811

High

383551

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

20

High-throughput

0.778

High

454806

KSYK
Tyrosine-protein kinase SYK

2

20

Small-scale

0.775

High

454804

STAT3
Signal transducer and activator of transcription 3

2

16

Small-scale

0.767

High

454826

CDK18
Cyclin-dependent kinase 18

2

14

High-throughput

0.754

High

454844

DOK1
Docking protein 1

2

20

Small-scale

0.738

High

414692

CDK1
Cyclin-dependent kinase 1

2

12

High-throughput

0.737

High

454829

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

2

11

High-throughput

0.737

High

441406

MET
Hepatocyte growth factor receptor

1

20

High-throughput

0.692

High

454791

KIT
Mast/stem cell growth factor receptor Kit

1

20

High-throughput

0.692

High

118679

AIP
AH receptor-interacting protein

1

13

High-throughput

0.691

High

454792

CDK4
Cyclin-dependent kinase 4

1

13

High-throughput

0.691

High

454794

SRC
Proto-oncogene tyrosine-protein kinase Src

1

20

High-throughput

0.691

High

454830

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

1

13

High-throughput

0.691

High

431451

HS90A
Heat shock protein HSP 90-alpha

4

20

Small-scale

0.672

High

454805

WASP
Actin nucleation-promoting factor WAS

3

20

Small-scale

0.670

High

454842

SH3K1
SH3 domain-containing kinase-binding protein 1

1

20

Small-scale

0.665

High

454835

CDC37
Hsp90 co-chaperone Cdc37

3

13

High-throughput

0.650

High

454795

HCLS1
Hematopoietic lineage cell-specific protein

1

20

Small-scale

0.647

High

454797

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

20

High-throughput

0.647

High

454834

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

High-throughput

0.647

High

454841

ABI1
Abl interactor 1

1

20

Small-scale

0.647

High

454848

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

14

Small-scale

0.647

High

437823

HS90B
Heat shock protein HSP 90-beta

3

20

High-throughput

0.643

High

454851

NEMO
NF-kappa-B essential modulator

2

20

Small-scale

0.624

High

269515

SKAP2
Src kinase-associated phosphoprotein 2

1

20

Small-scale

0.621

High

454787

FGR
Tyrosine-protein kinase Fgr

1

19

High-throughput

0.618

High

454802

FLT3
Receptor-type tyrosine-protein kinase FLT3

1

20

Small-scale

0.618

High

454810

CDK9
Cyclin-dependent kinase 9

1

20

High-throughput

0.618

High

454825

FAK1
Focal adhesion kinase 1

1

20

Small-scale

0.618

High

454827

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

2

20

Small-scale

0.571

High

323557

BAG2
BAG family molecular chaperone regulator 2

2

3

High-throughput

0.571

High

388170

HSPB1
Heat shock protein beta-1

2

6

High-throughput

0.571

High

432515

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

2

13

High-throughput

0.571

High

444817

ANXA5
Annexin A5

2

1

High-throughput

0.571

High

454793

PRPS2
Ribose-phosphate pyrophosphokinase 2

2

10

High-throughput

0.571

High

454796

TCPA
T-complex protein 1 subunit alpha

2

20

High-throughput

0.571

High

454798

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

2

12

High-throughput

0.571

High

454801

PYR1
Multifunctional protein CAD

2

3

High-throughput

0.571

High

454803

TCPZ
T-complex protein 1 subunit zeta

2

20

High-throughput

0.571

High

454808

TCPE
T-complex protein 1 subunit epsilon

2

20

High-throughput

0.571

High

454809

TCPG
T-complex protein 1 subunit gamma

2

20

High-throughput

0.571

High

454811

TCPQ
T-complex protein 1 subunit theta

2

20

High-throughput

0.571

High

454812

TCPD
T-complex protein 1 subunit delta

2

20

High-throughput

0.571

High

454813

FXR1
RNA-binding protein FXR1

2

5

High-throughput

0.571

High

454818

ACTB
Actin, cytoplasmic 1

2

5

High-throughput

0.571

High

454819

PRPS1
Ribose-phosphate pyrophosphokinase 1

2

10

High-throughput

0.571

High

454820

RL23
Large ribosomal subunit protein uL14

2

1

High-throughput

0.571

High

454821

TCPB
T-complex protein 1 subunit beta

2

20

High-throughput

0.571

High

454822

GSTO1
Glutathione S-transferase omega-1

2

2

High-throughput

0.571

High

454831

KPRA
Phosphoribosyl pyrophosphate synthase-associated protein 1

2

10

High-throughput

0.571

High

454832

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

2

5

High-throughput

0.571

High

454840

RBP10
Ran-binding protein 10

2

4

High-throughput

0.571

High

454843

PGAM5
Serine/threonine-protein phosphatase PGAM5, mitochondrial

2

2

High-throughput

0.571

High

454845

TCPH
T-complex protein 1 subunit eta

2

20

High-throughput

0.571

High

454846

GHC2
Mitochondrial glutamate carrier 2

2

6

High-throughput

0.571

High

454847

GHC1
Mitochondrial glutamate carrier 1

2

6

High-throughput

0.571

High

454849

ATD3A
ATPase family AAA domain-containing protein 3A

2

1

High-throughput

0.571

High

454850

COR1C
Coronin-1C

2

5

High-throughput

0.571

High

454816

COPA
Coatomer subunit alpha

2

0

High-throughput

0.547

High

454817

TPIS
Triosephosphate isomerase

2

0

High-throughput

0.547

High

454836

QPCT
Glutaminyl-peptide cyclotransferase

2

0

High-throughput

0.547

High

265847

NR1I2
Nuclear receptor subfamily 1 group I member 2

1

14

High-throughput

0.541

High

454790

ANDR
Androgen receptor

1

20

High-throughput

0.536

High

396309

APOD
Apolipoprotein D

1

1

High-throughput

0.536

High

454789

H2AZ
Histone H2A.Z

1

1

High-throughput

0.536

High

241259

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

2

12

High-throughput

0.521

High

454815

ROA3
Heterogeneous nuclear ribonucleoprotein A3

2

15

High-throughput

0.521

High

454788

LOX5
Polyunsaturated fatty acid 5-lipoxygenase

1

6

Small-scale

0.501

High

454807

TNFL6
Tumor necrosis factor ligand superfamily member 6

1

12

Small-scale

0.501

High

454823

DAB2
Disabled homolog 2

1

20

Small-scale

0.501

High

302823

HEXI1
Protein HEXIM1

1

6

High-throughput

0.479

High

454799

CBL
E3 ubiquitin-protein ligase CBL

1

20

Small-scale

0.479

High

454800

CD24
Signal transducer CD24

1

1

Small-scale

0.479

High

454814

CCR3
C-C chemokine receptor type 3

1

6

Small-scale

0.479

High

454824

UPAR
Urokinase plasminogen activator surface receptor

1

2

Small-scale

0.479

High

454828

SLAF1
Signaling lymphocytic activation molecule

1

20

Small-scale

0.479

High

454833

KIF14
Kinesin-like protein KIF14

1

9

High-throughput

0.479

High

454837

LARP7
La-related protein 7

1

12

High-throughput

0.479

High

454838

H90B3
Putative heat shock protein HSP 90-beta-3

1

20

High-throughput

0.445

High

454839

H90B2
Putative heat shock protein HSP 90-beta 2

1

20

High-throughput

0.445

High


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Last updated: 15 Jul 2024