Protein: IRF5
Interferon regulatory factor 5 (IRF-5)

Gene: IRF5
Organism: Homo sapiens
Interactions: 72
UniProt ID: Q13568

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0002376 - immune system process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1039450

IRF5
Interferon regulatory factor 5

6

15

Small-scale

0.943

High

1039460

CBP
CREB-binding protein

2

17

Small-scale

0.834

High

1039452

IRF3
Interferon regulatory factor 3

2

16

Small-scale

0.768

High

1039463

IRF7
Interferon regulatory factor 7

2

15

Small-scale

0.754

High

998671

EP300
Histone acetyltransferase p300

1

18

Small-scale

0.724

High

157829

IRF6
Interferon regulatory factor 6

1

15

High-throughput

0.691

High

302514

CE152
Centrosomal protein of 152 kDa

3

4

High-throughput

0.656

High

1039469

MYD88
Myeloid differentiation primary response protein MyD88

2

20

Small-scale

0.624

High

501047

IRF1
Interferon regulatory factor 1

1

15

Small-scale

0.618

High

786340

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

20

Small-scale

0.618

High

855295

STAT2
Signal transducer and activator of transcription 2

1

20

Small-scale

0.618

High

962709

IRF9
Interferon regulatory factor 9

1

17

Small-scale

0.618

High

1024155

CSN1
COP9 signalosome complex subunit 1

2

3

Small-scale

0.611

High

978745

TF65
Transcription factor p65

2

20

Small-scale

0.601

High

1039458

MAVS
Mitochondrial antiviral-signaling protein

1

5

High-throughput

0.586

High

667334

IL12A
Interleukin-12 subunit alpha

2

7

Small-scale

0.584

High

1039479

TRAF6
TNF receptor-associated factor 6

2

20

Small-scale

0.584

High

213542

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

1

6

High-throughput

0.573

High

584953

RO52
E3 ubiquitin-protein ligase TRIM21

1

8

Small-scale

0.561

High

1038353

HDAC1
Histone deacetylase 1

1

5

Small-scale

0.561

High

1039477

CSN3
COP9 signalosome complex subunit 3

1

5

Small-scale

0.561

High

1039480

NCOR2
Nuclear receptor corepressor 2

1

6

Small-scale

0.561

High

1039472

TRI15
E3 ubiquitin-protein ligase TRIM15

1

10

High-throughput

0.541

High

1039465

SIN3A
Paired amphipathic helix protein Sin3a

1

0

Small-scale

0.537

High

118862

GTPB1
GTP-binding protein 1

1

2

High-throughput

0.536

High

550383

ZEP1
Zinc finger protein 40

1

1

High-throughput

0.536

High

834899

RGS3
Regulator of G-protein signaling 3

1

2

High-throughput

0.536

High

352753

IFNA1
Interferon alpha-1/13

1

20

Small-scale

0.515

High

352842

IFN14
Interferon alpha-14

1

20

Small-scale

0.515

High

614312

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

1

High-throughput

0.515

High

1029391

TIF1B
Transcription intermediary factor 1-beta

1

15

Small-scale

0.515

High

1039454

SETB1
Histone-lysine N-methyltransferase SETDB1

1

3

Small-scale

0.515

High

176184

PPM1G
Protein phosphatase 1G

1

0

High-throughput

0.513

High

924551

GRB2
Growth factor receptor-bound protein 2

1

0

High-throughput

0.513

High

1039475

TBK1
Serine/threonine-protein kinase TBK1

1

14

Small-scale

0.501

High

148776

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.500

High

1039466

PSB7
Proteasome subunit beta type-7

1

9

High-throughput

0.500

High

1039471

GTPB2
GTP-binding protein 2

1

2

High-throughput

0.489

High

1039459

S15A4
Solute carrier family 15 member 4

1

1

Small-scale

0.484

High

154360

TR10B
Tumor necrosis factor receptor superfamily member 10B

1

1

Small-scale

0.479

High

162717

XPO1
Exportin-1

1

3

Small-scale

0.479

High

166923

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

3

High-throughput

0.479

High

167542

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

15

Small-scale

0.479

High

174865

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

2

Small-scale

0.479

High

238672

IMA7
Importin subunit alpha-7

1

5

Small-scale

0.479

High

261501

NCOR1
Nuclear receptor corepressor 1

1

7

Small-scale

0.479

High

352882

IFNB
Interferon beta

1

20

Small-scale

0.479

High

386687

P53
Cellular tumor antigen p53

1

4

Small-scale

0.479

High

606846

IL10
Interleukin-10

1

1

Small-scale

0.479

High

667349

IL12B
Interleukin-12 subunit beta

1

8

Small-scale

0.479

High

841070

TNF10
Tumor necrosis factor ligand superfamily member 10

1

7

Small-scale

0.479

High

853590

IMA5
Importin subunit alpha-5

1

5

Small-scale

0.479

High

897241

CSN2
COP9 signalosome complex subunit 2

1

5

Small-scale

0.479

High

1035701

BIRC3
Baculoviral IAP repeat-containing protein 3

1

3

Small-scale

0.479

High

1039453

CASP8
Caspase-8

1

3

Small-scale

0.479

High

1039455

PP6R3
Serine/threonine-protein phosphatase 6 regulatory subunit 3

1

2

High-throughput

0.479

High

1039457

CSN6
COP9 signalosome complex subunit 6

1

1

Small-scale

0.479

High

1039461

KAT2B
Histone acetyltransferase KAT2B

1

8

Small-scale

0.479

High

1039462

CSN5
COP9 signalosome complex subunit 5

1

2

Small-scale

0.479

High

1039464

PELI1
E3 ubiquitin-protein ligase pellino homolog 1

1

1

Small-scale

0.479

High

1039468

CCL19
C-C motif chemokine 19

1

10

Small-scale

0.479

High

1039470

CSN4
COP9 signalosome complex subunit 4

1

1

Small-scale

0.479

High

1039473

IL23A
Interleukin-23 subunit alpha

1

2

Small-scale

0.479

High

1039476

PACN2
Protein kinase C and casein kinase substrate in neurons protein 2

1

1

High-throughput

0.479

High

1039478

PP6R1
Serine/threonine-protein phosphatase 6 regulatory subunit 1

1

2

High-throughput

0.479

High

235277

OGA
Protein O-GlcNAcase

1

0

Small-scale

0.458

High

1039456

WAC2A
WASH complex subunit 2A

1

0

High-throughput

0.458

High

1039467

CSN8
COP9 signalosome complex subunit 8

1

0

Small-scale

0.458

High

1039474

CSN7A
COP9 signalosome complex subunit 7a

1

0

Small-scale

0.458

High

1039451

FLOT2
Flotillin-2

1

6

High-throughput

0.457

High

456407

PPBI
Intestinal-type alkaline phosphatase

1

0

Small-scale

0.292

High


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Last updated: 15 Jul 2024