Protein: DI3L1
DIS3-like exonuclease 1 (EC 3.1.13.1)

Gene: DI3L1, DIS3L
Organism: Homo sapiens
Interactions: 45
UniProt ID: Q8TF46

Gene Ontology (top 5):
GO:0000175 - 3'-5'-RNA exonuclease activity
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0003723 - RNA binding
GO:0005813 - centrosome
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1257149

EXOS8
Exosome complex component RRP43

6

19

Small-scale

0.952

High

1063744

EXOS7
Exosome complex component RRP42

5

19

Small-scale

0.930

High

1257153

EXOS4
Exosome complex component RRP41

4

19

Small-scale

0.912

High

1257154

EXOS5
Exosome complex component RRP46

4

20

Small-scale

0.909

High

986702

EXOS9
Exosome complex component RRP45

3

20

Small-scale

0.867

High

1130037

EXOS6
Exosome complex component MTR3

3

20

Small-scale

0.861

High

1257155

EXOS3
Exosome complex component RRP40

8

4

Small-scale

0.754

High

1257157

EXOS1
Exosome complex component CSL4

5

10

Small-scale

0.723

High

1046312

EXOS2
Exosome complex component RRP4

5

5

Small-scale

0.722

High

1257158

HBS1L
HBS1-like protein

4

1

Small-scale

0.699

High

966442

EXOSX
Exosome complex component 10

3

5

Small-scale

0.667

High

1167938

GGYF2
GRB10-interacting GYF protein 2

3

1

Small-scale

0.667

High

237277

IF4E2
Eukaryotic translation initiation factor 4E type 2

2

2

Small-scale

0.611

High

1257151

MPH6
M-phase phosphoprotein 6

2

1

High-throughput

0.611

High

322914

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

2

1

High-throughput

0.584

High

786991

MTREX
Exosome RNA helicase MTR4

2

7

Small-scale

0.584

High

442335

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

3

High-throughput

0.536

High

555560

H2AX
Histone H2AX

1

3

High-throughput

0.536

High

1047030

C1D
Nuclear nucleic acid-binding protein C1D

1

1

High-throughput

0.536

High

1101735

CF184
Cilia- and flagella-associated protein 184

1

0

High-throughput

0.513

High

1199650

ZN598
E3 ubiquitin-protein ligase ZNF598

1

0

Small-scale

0.513

High

883175

HUNK
Hormonally up-regulated neu tumor-associated kinase

1

1

High-throughput

0.494

High

1191488

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.493

High

1170075

SRCAP
Helicase SRCAP

1

2

High-throughput

0.489

High

118890

GTPB1
GTP-binding protein 1

1

2

High-throughput

0.479

High

163047

XPO1
Exportin-1

1

2

High-throughput

0.479

High

1257159

RBM7
RNA-binding protein 7

1

3

High-throughput

0.479

High

857006

THOP1
Thimet oligopeptidase

1

0

High-throughput

0.458

High

1059004

STAT4
Signal transducer and activator of transcription 4

1

0

High-throughput

0.458

High

1086076

CDKN3
Cyclin-dependent kinase inhibitor 3

1

0

High-throughput

0.458

High

1157887

ZCHC8
Zinc finger CCHC domain-containing protein 8

1

0

High-throughput

0.458

High

1206002

MIB1
E3 ubiquitin-protein ligase MIB1

1

0

High-throughput

0.458

High

1254198

BICD2
Protein bicaudal D homolog 2

1

0

High-throughput

0.458

High

1257148

CNOT9
CCR4-NOT transcription complex subunit 9

1

0

High-throughput

0.458

High

1257150

EYA3
Eyes absent homolog 3

1

0

High-throughput

0.458

High

1257156

BRPF3
Bromodomain and PHD finger-containing protein 3

1

0

High-throughput

0.458

High

1138200

BRE1A
E3 ubiquitin-protein ligase BRE1A

1

1

High-throughput

0.439

High

1165631

LCN15
Lipocalin-15

3

0

High-throughput

0.347

High

1137032

LIN9
Protein lin-9 homolog

2

0

High-throughput

0.328

High

1257152

IQCN
IQ domain-containing protein N

2

0

High-throughput

0.328

High

1051180

BTG3
Protein BTG3

1

0

High-throughput

0.282

High

519045

PIP
Prolactin-inducible protein

1

0

High-throughput

0.279

Low

1173194

PAXI1
PAX-interacting protein 1

1

0

High-throughput

0.251

Low

1242031

RN214
RING finger protein 214

1

0

High-throughput

0.249

Low

886313

DSCR9
Down syndrome critical region protein 9

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024