Protein: ITA5
Integrin alpha-5 (CD49 antigen-like family member E) (Fibronectin receptor subunit alpha) (Integrin alpha-F) (VLA-5) (CD antigen CD49e) [Cleaved into: Integrin alpha-5 heavy chain; Integrin alpha-5 light chain]

Gene: ITA5, ITGA5
Organism: Homo sapiens
Interactions: 117
UniProt ID: P08648

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0001618 - virus receptor activity
GO:0001726 - ruffle
GO:0005154 - epidermal growth factor receptor binding
GO:0005161 - platelet-derived growth factor receptor binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

403743

ITB1
Integrin beta-1

12

20

Small-scale

0.978

High

396555

ITB3
Integrin beta-3

2

20

Small-scale

0.768

High

362715

FINC
Fibronectin

8

6

Small-scale

0.753

High

121084

LEG8
Galectin-8

6

20

Small-scale

0.730

High

443088

ADA32
Disintegrin and metalloproteinase domain-containing protein 32

2

4

High-throughput

0.628

High

443034

ITB5
Integrin beta-5

1

20

Small-scale

0.618

High

119100

LEG9
Galectin-9

2

20

Small-scale

0.611

High

443058

CD81
CD81 antigen

2

20

Small-scale

0.601

High

168290

ANGP2
Angiopoietin-2

2

5

Small-scale

0.595

High

349814

RASK
GTPase KRas

2

20

High-throughput

0.584

High

443024

LAMP1
Lysosome-associated membrane glycoprotein 1

2

5

High-throughput

0.584

High

443096

SHRPN
Sharpin

2

7

Small-scale

0.574

High

443092

TAFA4
Chemokine-like protein TAFA-4

2

4

High-throughput

0.574

High

443039

CD9
CD9 antigen

2

20

Small-scale

0.571

High

171921

GP182
G-protein coupled receptor 182

1

2

High-throughput

0.541

High

443051

GRK6
G protein-coupled receptor kinase 6

1

4

High-throughput

0.541

High

158889

NCTR3
Natural cytotoxicity triggering receptor 3

1

1

High-throughput

0.536

High

443022

LEG1
Galectin-1

1

20

High-throughput

0.536

High

443027

MMP9
Matrix metalloproteinase-9

1

8

Small-scale

0.536

High

443032

LEG3
Galectin-3

1

20

High-throughput

0.536

High

443040

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

2

High-throughput

0.536

High

443055

BAP31
B-cell receptor-associated protein 31

1

1

High-throughput

0.536

High

443072

IL5RA
Interleukin-5 receptor subunit alpha

1

2

High-throughput

0.536

High

443074

PCDH1
Protocadherin-1

1

9

High-throughput

0.536

High

443078

RAB35
Ras-related protein Rab-35

1

7

High-throughput

0.536

High

443085

BTNL3
Butyrophilin-like protein 3

1

11

High-throughput

0.536

High

443089

T106A
Transmembrane protein 106A

1

5

High-throughput

0.536

High

443095

TMPSD
Transmembrane protease serine 13

1

11

High-throughput

0.536

High

443097

CAD23
Cadherin-23

1

4

High-throughput

0.536

High

443102

PICK1
PRKCA-binding protein

1

4

High-throughput

0.536

High

443106

PA2GE
Group IIE secretory phospholipase A2

1

1

High-throughput

0.536

High

443109

BTNL2
Butyrophilin-like protein 2

1

11

High-throughput

0.536

High

443110

FBX2
F-box only protein 2

1

11

High-throughput

0.536

High

443111

ST14
Suppressor of tumorigenicity 14 protein

1

11

High-throughput

0.536

High

443101

FBX6
F-box only protein 6

2

11

High-throughput

0.533

High

158142

GIPC1
PDZ domain-containing protein GIPC1

1

1

Small-scale

0.527

High

317700

STABP
STAM-binding protein

1

0

High-throughput

0.518

High

443031

EGLN
Endoglin

1

1

Small-scale

0.515

High

443082

TENS2
Tensin-2

1

3

High-throughput

0.515

High

443026

CD59
CD59 glycoprotein

1

0

High-throughput

0.513

High

443067

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

0

High-throughput

0.513

High

443094

UBAC1
Ubiquitin-associated domain-containing protein 1

1

0

High-throughput

0.513

High

443029

TIMP2
Metalloproteinase inhibitor 2

1

1

Small-scale

0.512

High

372979

VTNC
Vitronectin

1

5

Small-scale

0.501

High

443036

VINC
Vinculin

1

3

Small-scale

0.501

High

443044

L1CAM
Neural cell adhesion molecule L1

1

1

Small-scale

0.501

High

443075

LG3BP
Galectin-3-binding protein

1

2

Small-scale

0.501

High

256205

BRE1B
E3 ubiquitin-protein ligase BRE1B

1

3

High-throughput

0.489

High

319500

LY86
Lymphocyte antigen 86

1

2

High-throughput

0.489

High

443025

PSPC
Surfactant protein C

1

5

High-throughput

0.489

High

443043

LCN1
Lipocalin-1

1

5

High-throughput

0.489

High

443057

DEF1
Neutrophil defensin 1

1

2

High-throughput

0.489

High

443081

RN123
E3 ubiquitin-protein ligase RNF123

1

5

High-throughput

0.489

High

443083

WDR25
WD repeat-containing protein 25

1

1

High-throughput

0.489

High

443090

LEG12
Galectin-12

1

20

High-throughput

0.489

High

443112

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

5

Small-scale

0.481

High

443105

UBAP1
Ubiquitin-associated protein 1

1

0

Small-scale

0.480

High

120283

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

146095

PLPP3
Phospholipid phosphatase 3

1

1

Small-scale

0.479

High

155248

NRP1
Neuropilin-1

1

4

Small-scale

0.479

High

204953

TGON2
Trans-Golgi network integral membrane protein 2

1

9

High-throughput

0.479

High

337805

EGFR
Epidermal growth factor receptor

1

11

Small-scale

0.479

High

348477

RASN
GTPase NRas

1

20

High-throughput

0.479

High

349073

RASH
GTPase HRas

1

13

High-throughput

0.479

High

361969

FIBG
Fibrinogen gamma chain

1

5

Small-scale

0.479

High

436126

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.479

High

443023

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

4

Small-scale

0.479

High

443028

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.479

High

443030

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.479

High

443038

FGFR2
Fibroblast growth factor receptor 2

1

7

Small-scale

0.479

High

443041

CBL
E3 ubiquitin-protein ligase CBL

1

5

Small-scale

0.479

High

443045

TSP4
Thrombospondin-4

1

5

Small-scale

0.479

High

443046

VGFR2
Vascular endothelial growth factor receptor 2

1

6

Small-scale

0.479

High

443047

TGFR1
TGF-beta receptor type-1

1

4

Small-scale

0.479

High

443048

ACVL1
Serine/threonine-protein kinase receptor R3

1

4

Small-scale

0.479

High

443050

VHL
von Hippel-Lindau disease tumor suppressor

1

4

Small-scale

0.479

High

443054

RAB7A
Ras-related protein Rab-7a

1

7

High-throughput

0.479

High

443056

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.479

High

443059

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

443060

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

443061

RAB2A
Ras-related protein Rab-2A

1

6

High-throughput

0.479

High

443062

CXCR4
C-X-C chemokine receptor type 4

1

2

Small-scale

0.479

High

443063

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

443064

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.479

High

443065

ARF6
ADP-ribosylation factor 6

1

7

High-throughput

0.479

High

443066

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.479

High

443068

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

443071

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

443073

CAV1
Caveolin-1

1

4

High-throughput

0.479

High

443076

ILK
Integrin-linked protein kinase

1

2

Small-scale

0.479

High

443077

ADA15
Disintegrin and metalloproteinase domain-containing protein 15

1

4

Small-scale

0.479

High

443079

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.479

High

443080

CAH9
Carbonic anhydrase 9

1

6

High-throughput

0.479

High

443087

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.479

High

443093

CIB1
Calcium and integrin-binding protein 1

1

2

Small-scale

0.479

High

443098

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

443099

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

443103

T106B
Transmembrane protein 106B

1

5

High-throughput

0.479

High

443108

SE1L1
Protein sel-1 homolog 1

1

7

Small-scale

0.479

High

443033

IBP2
Insulin-like growth factor-binding protein 2

1

0

Small-scale

0.458

High

443042

CD40L
CD40 ligand

1

0

Small-scale

0.458

High

443070

X3CL1
Fractalkine

1

0

Small-scale

0.458

High

443053

CLK1
Dual specificity protein kinase CLK1

1

1

High-throughput

0.457

High

443037

VCAM1
Vascular cell adhesion protein 1

1

4

High-throughput

0.445

High

443049

COIA1
Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin; Non-collagenous domain 1

1

7

Small-scale

0.445

High

443052

MSS4
Guanine nucleotide exchange factor MSS4

1

3

Small-scale

0.439

High

171190

CTDSL
CTD small phosphatase-like protein

1

2

High-throughput

0.437

High

377024

GCR
Glucocorticoid receptor

1

1

High-throughput

0.437

High

443069

RNF4
E3 ubiquitin-protein ligase RNF4

1

4

High-throughput

0.437

High

443084

VIR
Protein virilizer homolog

1

1

High-throughput

0.437

High

443086

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.437

High

443100

ST7
Suppressor of tumorigenicity 7 protein

1

2

High-throughput

0.437

High

443104

OTULL
Inactive ubiquitin thioesterase OTULINL

1

3

High-throughput

0.437

High

217765

ORC4
Origin recognition complex subunit 4

1

0

High-throughput

0.279

Low

443091

MTNB
Methylthioribulose-1-phosphate dehydratase

1

0

High-throughput

0.279

Low

443107

TXD16
Thioredoxin domain-containing protein 16

1

0

High-throughput

0.279

Low

443035

EGR1
Early growth response protein 1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024