Protein: CD63
CD63 antigen (Granulophysin) (Lysosomal-associated membrane protein 3) (LAMP-3) (Lysosome integral membrane protein 1) (Limp1) (Melanoma-associated antigen ME491) (OMA81H) (Ocular melanoma-associated antigen) (Tetraspanin-30) (Tspan-30) (CD antigen CD63)

Gene: CD63
Organism: Homo sapiens
Interactions: 104
UniProt ID: P08962

Gene Ontology (top 5):
GO:0002092 - positive regulation of receptor internalization
GO:0005615 - extracellular space
GO:0005654 - nucleoplasm
GO:0005765 - lysosomal membrane
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

446010

CD9
CD9 antigen

3

17

Small-scale

0.817

High

237713

TSN2
Tetraspanin-2

2

19

High-throughput

0.811

High

344783

TIMP1
Metalloproteinase inhibitor 1

4

1

Small-scale

0.700

High

326011

TSN15
Tetraspanin-15

1

17

High-throughput

0.691

High

446021

TSN31
Tetraspanin-31

1

2

High-throughput

0.691

High

119104

LEG9
Galectin-9

3

8

High-throughput

0.667

High

121086

LEG8
Galectin-8

3

8

High-throughput

0.667

High

446007

LEG3
Galectin-3

3

8

High-throughput

0.667

High

446028

WLS
Protein wntless homolog

3

4

Small-scale

0.656

High

403744

ITB1
Integrin beta-1

3

19

Small-scale

0.640

High

237778

TSN3
Tetraspanin-3

1

17

High-throughput

0.618

High

446012

CD82
CD82 antigen

1

19

Small-scale

0.618

High

207535

RNF13
E3 ubiquitin-protein ligase RNF13

2

7

High-throughput

0.611

High

446037

RETR3
Reticulophagy regulator 3

3

7

High-throughput

0.609

High

132718

SDCB1
Syntenin-1

2

2

Small-scale

0.595

High

446019

PAR2
Proteinase-activated receptor 2

1

20

High-throughput

0.541

High

170026

PLS1
Phospholipid scramblase 1

1

3

High-throughput

0.536

High

179339

MRP4
ATP-binding cassette sub-family C member 4

1

2

High-throughput

0.536

High

234090

FADS1
Acyl-CoA

1

4

High-throughput

0.536

High

258894

RTN2
Reticulon-2

1

4

High-throughput

0.536

High

446004

SC5A1
Sodium/glucose cotransporter 1

1

4

High-throughput

0.536

High

446006

NCPR
NADPH--cytochrome P450 reductase

1

3

High-throughput

0.536

High

446009

SYT1
Synaptotagmin-1

1

1

High-throughput

0.536

High

446011

FPR2
N-formyl peptide receptor 2

1

18

High-throughput

0.536

High

446013

CALX
Calnexin

1

5

High-throughput

0.536

High

446020

KDSR
3-ketodihydrosphingosine reductase

1

9

High-throughput

0.536

High

446023

RAB35
Ras-related protein Rab-35

1

2

High-throughput

0.536

High

446024

CP2AD
Cytochrome P450 2A13

1

1

High-throughput

0.536

High

446025

SC5A9
Sodium/glucose cotransporter 4

1

4

High-throughput

0.536

High

446027

HSDL1
Inactive hydroxysteroid dehydrogenase-like protein 1

1

5

High-throughput

0.536

High

446029

ZDH20
Palmitoyltransferase ZDHHC20

1

8

High-throughput

0.536

High

446034

S27A4
Long-chain fatty acid transport protein 4

1

6

High-throughput

0.536

High

446047

YIPF5
Protein YIPF5

1

1

High-throughput

0.536

High

446049

F241B
Protein FAM241B

1

2

High-throughput

0.536

High

446050

HVCN1
Voltage-gated hydrogen channel 1

1

5

High-throughput

0.536

High

446063

TMM43
Transmembrane protein 43

1

2

High-throughput

0.536

High

446067

CCG6
Voltage-dependent calcium channel gamma-6 subunit

1

1

High-throughput

0.536

High

446070

LMA2L
VIP36-like protein

1

2

High-throughput

0.536

High

446075

PDXL2
Podocalyxin-like protein 2

1

1

High-throughput

0.536

High

446076

GPC5B
G-protein coupled receptor family C group 5 member B

1

4

High-throughput

0.536

High

321325

STR3N
STARD3 N-terminal-like protein

1

0

High-throughput

0.513

High

446022

LAPM5
Lysosomal-associated transmembrane protein 5

1

0

High-throughput

0.513

High

446030

MBLC2
Acyl-coenzyme A thioesterase MBLAC2

1

0

High-throughput

0.513

High

446062

TMM47
Transmembrane protein 47

1

0

High-throughput

0.513

High

446068

YIPF3
Protein YIPF3

1

0

High-throughput

0.513

High

446008

SDC1
Syndecan-1

1

3

Small-scale

0.501

High

161005

CLGN
Calmegin

1

5

High-throughput

0.489

High

446017

GPDM
Glycerol-3-phosphate dehydrogenase, mitochondrial

1

2

High-throughput

0.489

High

446026

ALG11
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase

1

4

High-throughput

0.489

High

446031

LEG9C
Galectin-9C

1

8

High-throughput

0.489

High

446033

MBOA5
Lysophospholipid acyltransferase 5

1

3

High-throughput

0.489

High

446035

LCLT1
Lysocardiolipin acyltransferase 1

1

15

High-throughput

0.489

High

446040

GHDC
GH3 domain-containing protein

1

5

High-throughput

0.489

High

446042

FITM2
Acyl-coenzyme A diphosphatase FITM2

1

3

High-throughput

0.489

High

446044

BRI3B
BRI3-binding protein

1

2

High-throughput

0.489

High

446046

CDS1
Phosphatidate cytidylyltransferase 1

1

3

High-throughput

0.489

High

446048

T4S18
Transmembrane 4 L6 family member 18

1

1

High-throughput

0.489

High

446051

TV23C
Golgi apparatus membrane protein TVP23 homolog C

1

2

High-throughput

0.489

High

446052

ALG14
UDP-N-acetylglucosamine transferase subunit ALG14

1

1

High-throughput

0.489

High

446053

CERS2
Ceramide synthase 2

1

3

High-throughput

0.489

High

446055

REEP6
Receptor expression-enhancing protein 6

1

6

High-throughput

0.489

High

446056

F210B
Protein FAM210B, mitochondrial

1

7

High-throughput

0.489

High

446057

DIESL
DGAT1/2-independent enzyme synthesizing storage lipids

1

3

High-throughput

0.489

High

446058

F210A
Protein FAM210A

1

7

High-throughput

0.489

High

446059

SGMR1
Sigma non-opioid intracellular receptor 1

1

1

High-throughput

0.489

High

446071

REEP4
Receptor expression-enhancing protein 4

1

6

High-throughput

0.489

High

446072

ZDHC6
Palmitoyltransferase ZDHHC6

1

10

High-throughput

0.489

High

446073

TMT1A
Thiol S-methyltransferase TMT1A

1

1

High-throughput

0.489

High

173261

S22A2
Solute carrier family 22 member 2

1

6

Small-scale

0.481

High

173335

S22A1
Solute carrier family 22 member 1

1

6

Small-scale

0.481

High

446016

GLP1R
Glucagon-like peptide 1 receptor

1

14

Small-scale

0.481

High

305913

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

3

Small-scale

0.479

High

354662

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

8

Small-scale

0.479

High

445999

KIT
Mast/stem cell growth factor receptor Kit

1

7

Small-scale

0.479

High

446000

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

446002

SRC
Proto-oncogene tyrosine-protein kinase Src

1

3

Small-scale

0.479

High

446003

DOB
HLA class II histocompatibility antigen, DO beta chain

1

5

Small-scale

0.479

High

446005

VATB1
V-type proton ATPase subunit B, kidney isoform

1

1

High-throughput

0.479

High

446014

DMB
HLA class II histocompatibility antigen, DM beta chain

1

8

Small-scale

0.479

High

446038

SMC5
Structural maintenance of chromosomes protein 5

1

4

High-throughput

0.479

High

446039

TM192
Transmembrane protein 192

1

3

High-throughput

0.479

High

446060

TS101
Tumor susceptibility gene 101 protein

1

1

Small-scale

0.479

High

446066

CLC7A
C-type lectin domain family 7 member A

1

14

Small-scale

0.479

High

446069

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

3

Small-scale

0.479

High

446077

FPRP
Prostaglandin F2 receptor negative regulator

1

20

Small-scale

0.479

High

446001

SRF
Serum response factor

1

0

Small-scale

0.460

High

446078

UBQL2
Ubiquilin-2

1

0

High-throughput

0.458

High

204532

PROM1
Prominin-1

1

1

Small-scale

0.457

High

446045

TSC1
Hamartin

1

8

Small-scale

0.457

High

152234

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

20

High-throughput

0.445

High

446015

VATA
V-type proton ATPase catalytic subunit A

1

2

High-throughput

0.445

High

446061

VKOR1
Vitamin K epoxide reductase complex subunit 1

1

5

Small-scale

0.439

High

446036

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.437

High

446043

RN149
E3 ubiquitin-protein ligase RNF149

1

8

High-throughput

0.437

High

446054

TMM80
Transmembrane protein 80

2

0

High-throughput

0.316

High

446018

BPL1
Biotin--protein ligase

1

0

High-throughput

0.279

Low

446032

IPIL1
Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1

1

0

High-throughput

0.279

Low

446041

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.279

Low

446064

TM208
Transmembrane protein 208

1

0

High-throughput

0.279

Low

446065

ABHEA
Protein ABHD14A

1

0

High-throughput

0.279

Low

446074

ALG13
UDP-N-acetylglucosamine transferase subunit ALG13

1

0

High-throughput

0.279

Low

446079

ANGE1
Protein angel homolog 1

1

0

High-throughput

0.279

Low

446080

DOLK
Dolichol kinase

1

0

High-throughput

0.279

Low

446081

UB2J1
Ubiquitin-conjugating enzyme E2 J1

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024