Protein: PTPRG
Receptor-type tyrosine-protein phosphatase gamma (Protein-tyrosine phosphatase gamma) (R-PTP-gamma) (EC 3.1.3.48)

Gene: PTPRG
Organism: Homo sapiens
Interactions: 119
UniProt ID: P23470

Gene Ontology (top 5):
GO:0004725 - protein tyrosine phosphatase activity
GO:0005001 - transmembrane receptor protein tyrosine phosphatase activity
GO:0005886 - plasma membrane
GO:0007169 - cell surface receptor protein tyrosine kinase signaling pathway
GO:0010633 - negative regulation of epithelial cell migration

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

617076

PTPRG
Receptor-type tyrosine-protein phosphatase gamma

2

19

Small-scale

0.815

High

617145

DUS22
Dual specificity protein phosphatase 22

2

1

High-throughput

0.811

High

617097

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.754

High

337943

EGFR
Epidermal growth factor receptor

2

20

Small-scale

0.743

High

617102

PKD1
Polycystin-1

1

6

Small-scale

0.713

High

617143

DUS23
Dual specificity protein phosphatase 23

1

4

High-throughput

0.691

High

134520

FCN1
Ficolin-1

3

4

High-throughput

0.667

High

182086

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

5

High-throughput

0.647

High

383612

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

High-throughput

0.647

High

384279

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.647

High

411298

INSR
Insulin receptor

1

20

High-throughput

0.647

High

411597

LCK
Tyrosine-protein kinase Lck

1

20

High-throughput

0.647

High

441434

MET
Hepatocyte growth factor receptor

1

20

High-throughput

0.647

High

452357

PGFRB
Platelet-derived growth factor receptor beta

1

17

High-throughput

0.647

High

581149

EPOR
Erythropoietin receptor

1

20

High-throughput

0.647

High

610228

CBL
E3 ubiquitin-protein ligase CBL

1

6

High-throughput

0.647

High

617077

MK03
Mitogen-activated protein kinase 3

1

11

High-throughput

0.647

High

617082

TIE1
Tyrosine-protein kinase receptor Tie-1

1

20

High-throughput

0.647

High

617084

CSK
Tyrosine-protein kinase CSK

1

20

High-throughput

0.647

High

617085

TEC
Tyrosine-protein kinase Tec

1

20

High-throughput

0.647

High

617103

TIE2
Angiopoietin-1 receptor

1

17

High-throughput

0.647

High

617150

ALK
ALK tyrosine kinase receptor

1

20

High-throughput

0.647

High

578825

SDC1
Syndecan-1

2

3

High-throughput

0.628

High

617151

PCDGK
Protocadherin gamma-C3

2

13

High-throughput

0.628

High

617101

DLG4
Disks large homolog 4

1

7

Small-scale

0.621

High

318066

DIRA3
GTP-binding protein Di-Ras3

1

3

High-throughput

0.618

High

348514

RASN
GTPase NRas

1

15

High-throughput

0.618

High

349881

RASK
GTPase KRas

1

17

High-throughput

0.618

High

433579

LYN
Tyrosine-protein kinase Lyn

1

20

High-throughput

0.618

High

564415

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.618

High

576984

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

17

Small-scale

0.618

High

616899

PTPRB
Receptor-type tyrosine-protein phosphatase beta

1

20

High-throughput

0.618

High

617087

MUC18
Cell surface glycoprotein MUC18

1

14

High-throughput

0.618

High

617091

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.618

High

617093

RAB2A
Ras-related protein Rab-2A

1

3

High-throughput

0.618

High

617094

RHOA
Transforming protein RhoA

1

20

High-throughput

0.618

High

617095

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.618

High

617100

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

617112

RAB35
Ras-related protein Rab-35

1

6

High-throughput

0.618

High

617113

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.618

High

617122

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.618

High

617129

PARD3
Partitioning defective 3 homolog

1

8

High-throughput

0.618

High

617133

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.618

High

617142

DUS26
Dual specificity protein phosphatase 26

1

1

High-throughput

0.618

High

617144

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.618

High

617154

MRCKB
Serine/threonine-protein kinase MRCK beta

1

4

High-throughput

0.618

High

121108

LEG8
Galectin-8

3

20

High-throughput

0.609

High

617125

SPA12
Serpin A12

2

0

High-throughput

0.602

High

617080

CTNB1
Catenin beta-1

2

20

Small-scale

0.595

High

617118

CXB7
Gap junction beta-7 protein

2

2

High-throughput

0.574

High

617121

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.553

High

617131

CSKI2
Caskin-2

1

7

High-throughput

0.553

High

617153

FARP1
FERM, ARHGEF and pleckstrin domain-containing protein 1

1

4

High-throughput

0.553

High

449193

LEG1
Galectin-1

1

20

High-throughput

0.536

High

572281

LEG3
Galectin-3

1

20

High-throughput

0.536

High

617132

NICA
Nicastrin

1

1

High-throughput

0.536

High

443334

VIME
Vimentin

1

1

High-throughput

0.515

High

617116

ARM12
Armadillo repeat-containing protein 12

1

0

High-throughput

0.513

High

580201

CADH2
Cadherin-2

1

20

High-throughput

0.501

High

617086

WASP
Actin nucleation-promoting factor WAS

1

6

High-throughput

0.501

High

617088

NSF
Vesicle-fusing ATPase

1

14

High-throughput

0.501

High

617089

PAXI
Paxillin

1

10

High-throughput

0.501

High

617106

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

9

High-throughput

0.501

High

119173

LEG9
Galectin-9

1

20

High-throughput

0.489

High

456375

CSF3
Granulocyte colony-stimulating factor

1

1

High-throughput

0.489

High

617107

SG2A2
Mammaglobin-A

1

1

High-throughput

0.489

High

617120

ZN517
Zinc finger protein 517

1

3

High-throughput

0.489

High

617136

CERS2
Ceramide synthase 2

1

4

High-throughput

0.489

High

617147

FBX2
F-box only protein 2

1

8

High-throughput

0.489

High

617110

PKD2
Polycystin-2

1

8

Small-scale

0.481

High

441699

CFAH
Complement factor H

1

5

Small-scale

0.479

High

506879

LAMP1
Lysosome-associated membrane glycoprotein 1

1

3

High-throughput

0.479

High

521728

CADH1
Cadherin-1

1

20

Small-scale

0.479

High

527298

LAMP2
Lysosome-associated membrane glycoprotein 2

1

3

High-throughput

0.479

High

544939

AMPN
Aminopeptidase N

1

1

High-throughput

0.479

High

566923

CXA1
Gap junction alpha-1 protein

1

2

High-throughput

0.479

High

617078

DPP4
Dipeptidyl peptidase 4

1

2

High-throughput

0.479

High

617081

MERL
Merlin

1

6

High-throughput

0.479

High

617090

LMAN1
Protein ERGIC-53

1

2

High-throughput

0.479

High

617096

ARF6
ADP-ribosylation factor 6

1

1

High-throughput

0.479

High

617099

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

1

High-throughput

0.479

High

617104

CAV1
Caveolin-1

1

1

High-throughput

0.479

High

617117

LTOR1
Ragulator complex protein LAMTOR1

1

3

High-throughput

0.479

High

617123

GRIN1
G protein-regulated inducer of neurite outgrowth 1

1

5

High-throughput

0.479

High

617124

TM11B
Transmembrane protease serine 11B

1

7

High-throughput

0.479

High

617134

CK052
Uncharacterized protein C11orf52

1

1

High-throughput

0.479

High

617141

NIBA2
Protein Niban 2

1

1

High-throughput

0.479

High

617149

S39AA
Zinc transporter ZIP10

1

4

High-throughput

0.479

High

617152

LAMP3
Lysosome-associated membrane glycoprotein 3

1

3

High-throughput

0.479

High

200370

HS12A
Heat shock 70 kDa protein 12A

1

0

High-throughput

0.458

High

274810

PALM
Paralemmin-1

1

0

High-throughput

0.458

High

617079

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.458

High

617083

ADDB
Beta-adducin

1

0

High-throughput

0.458

High

617092

ICLN
Methylosome subunit pICln

1

0

High-throughput

0.458

High

617105

FCHO2
F-BAR domain only protein 2

1

0

High-throughput

0.458

High

617114

OCLN
Occludin

1

0

High-throughput

0.458

High

617148

CDV3
Protein CDV3 homolog

1

0

High-throughput

0.458

High

617108

GAB1
GRB2-associated-binding protein 1

1

6

High-throughput

0.457

High

239785

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

5

High-throughput

0.445

High

617111

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

7

High-throughput

0.445

High

315519

SC24A
Protein transport protein Sec24A

1

1

High-throughput

0.437

High

617140

CEP89
Centrosomal protein of 89 kDa

1

2

High-throughput

0.437

High

617146

PSD3
PH and SEC7 domain-containing protein 3

1

2

High-throughput

0.437

High

617127

T185A
Transmembrane protein 185A

3

0

High-throughput

0.347

High

617137

UIF
UAP56-interacting factor

3

0

High-throughput

0.347

High

617139

CCNL2
Cyclin-L2

3

0

High-throughput

0.347

High

317545

DUS4L
tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like

2

0

High-throughput

0.328

High

617109

MED21
Mediator of RNA polymerase II transcription subunit 21

2

0

High-throughput

0.328

High

617135

ISG20
Interferon-stimulated gene 20 kDa protein

2

0

High-throughput

0.328

High

146799

CDKA1
Cyclin-dependent kinase 2-associated protein 1

1

0

High-throughput

0.279

Low

617115

PCGF3
Polycomb group RING finger protein 3

1

0

High-throughput

0.279

Low

617126

ACBD7
Acyl-CoA-binding domain-containing protein 7

1

0

High-throughput

0.279

Low

617128

NPB
Neuropeptide B

1

0

High-throughput

0.279

Low

617130

D104A
Beta-defensin 104

1

0

High-throughput

0.279

Low

617138

CLCC1
Chloride channel CLIC-like protein 1

1

0

High-throughput

0.279

Low

617155

IR3IP
Immediate early response 3-interacting protein 1

1

0

High-throughput

0.279

Low

617119

PACS1
Phosphofurin acidic cluster sorting protein 1

1

0

High-throughput

0.269

Low

617098

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024