Protein: ERD21
ER lumen protein-retaining receptor 1 (KDEL endoplasmic reticulum protein retention receptor 1) (KDEL receptor 1) (Putative MAPK-activating protein PM23)

Gene: ERD21, KDELR1
Organism: Homo sapiens
Interactions: 95
UniProt ID: P24390

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005046 - KDEL sequence binding
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005793 - endoplasmic reticulum-Golgi intermediate compartment

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

622712

UBQL4
Ubiquilin-4

2

1

High-throughput

0.628

High

622695

NPL4
Nuclear protein localization protein 4 homolog

2

0

High-throughput

0.602

High

622717

RN115
E3 ubiquitin-protein ligase RNF115

2

0

High-throughput

0.602

High

622668

RAC1
Ras-related C3 botulinum toxin substrate 1

2

1

High-throughput

0.571

High

622663

COPB
Coatomer subunit beta

2

0

Small-scale

0.569

High

622693

ARFG1
ADP-ribosylation factor GTPase-activating protein 1

2

0

Small-scale

0.569

High

226550

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

622679

DLG2
Disks large homolog 2

2

1

High-throughput

0.553

High

622699

DLG3
Disks large homolog 3

2

1

High-throughput

0.553

High

173664

SURF4
Surfeit locus protein 4

1

2

High-throughput

0.536

High

505337

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

2

High-throughput

0.536

High

528566

CFTR
Cystic fibrosis transmembrane conductance regulator

1

3

High-throughput

0.536

High

622656

EAA3
Excitatory amino acid transporter 3

1

1

High-throughput

0.536

High

622696

SPP2B
Signal peptide peptidase-like 2B

1

1

High-throughput

0.536

High

622701

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

4

High-throughput

0.536

High

622713

PLCC
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma

1

2

High-throughput

0.536

High

622716

UBQL1
Ubiquilin-1

1

2

High-throughput

0.536

High

368999

ESR1
Estrogen receptor

2

3

High-throughput

0.521

High

622674

SERC3
Serine incorporator 3

1

1

High-throughput

0.515

High

313917

PIGN
GPI ethanolamine phosphate transferase 1

1

0

High-throughput

0.513

High

622685

FA2H
Fatty acid 2-hydroxylase

1

0

High-throughput

0.513

High

622697

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.513

High

622705

SEC62
Translocation protein SEC62

1

0

High-throughput

0.513

High

622706

SGMR1
Sigma non-opioid intracellular receptor 1

1

0

High-throughput

0.513

High

622670

ARF1
ADP-ribosylation factor 1

1

3

Small-scale

0.501

High

622662

CCR9
C-C chemokine receptor type 9

1

4

High-throughput

0.494

High

622666

PAR2
Proteinase-activated receptor 2

1

7

High-throughput

0.494

High

622710

GPR35
G-protein coupled receptor 35

1

5

High-throughput

0.494

High

121680

PSD11
26S proteasome non-ATPase regulatory subunit 11

1

2

High-throughput

0.489

High

121933

PSD12
26S proteasome non-ATPase regulatory subunit 12

1

1

High-throughput

0.489

High

134362

ACKR2
Atypical chemokine receptor 2

1

4

High-throughput

0.489

High

156794

FFAR1
Free fatty acid receptor 1

1

9

High-throughput

0.489

High

299145

CSCL1
CSC1-like protein 1

1

1

High-throughput

0.489

High

328309

S1PR4
Sphingosine 1-phosphate receptor 4

1

3

High-throughput

0.489

High

580341

TSN8
Tetraspanin-8

1

1

High-throughput

0.489

High

622649

EDNRA
Endothelin-1 receptor

1

2

High-throughput

0.489

High

622651

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

4

High-throughput

0.489

High

622652

APJ
Apelin receptor

1

2

High-throughput

0.489

High

622654

P2RY2
P2Y purinoceptor 2

1

7

High-throughput

0.489

High

622655

VIPR2
Vasoactive intestinal polypeptide receptor 2

1

4

High-throughput

0.489

High

622676

PSMD6
26S proteasome non-ATPase regulatory subunit 6

1

1

High-throughput

0.489

High

622680

RABL3
Rab-like protein 3

1

4

High-throughput

0.489

High

622688

P2RY8
P2Y purinoceptor 8

1

7

High-throughput

0.489

High

622703

OPALI
Opalin

1

2

High-throughput

0.489

High

622714

GINM1
Glycoprotein integral membrane protein 1

1

1

High-throughput

0.489

High

622719

GPR45
Probable G-protein coupled receptor 45

1

2

High-throughput

0.489

High

205057

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.479

High

622648

ERD21
ER lumen protein-retaining receptor 1

1

1

Small-scale

0.479

High

622661

RAB7A
Ras-related protein Rab-7a

1

2

High-throughput

0.479

High

622677

SC23A
Protein transport protein Sec23A

1

1

Small-scale

0.479

High

622711

NEK6
Serine/threonine-protein kinase Nek6

1

2

High-throughput

0.470

High

568548

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

1

Small-scale

0.457

High

455097

PARP1
Poly [ADP-ribose] polymerase 1

1

1

High-throughput

0.437

High

622657

VDAC2
Voltage-dependent anion-selective channel protein 2

1

2

High-throughput

0.437

High

622659

MCM2
DNA replication licensing factor MCM2

1

2

High-throughput

0.437

High

622669

H31
Histone H3.1

1

1

High-throughput

0.437

High

622671

H33
Histone H3.3

1

1

High-throughput

0.437

High

622698

ESR2
Estrogen receptor beta

1

3

High-throughput

0.437

High

622707

RHOJ
Rho-related GTP-binding protein RhoJ

1

1

High-throughput

0.437

High

622681

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

622678

SC23B
Protein transport protein Sec23B

1

1

Small-scale

0.408

High

147596

TRAD1
TRAF-type zinc finger domain-containing protein 1

2

0

High-throughput

0.328

High

622672

UBE3A
Ubiquitin-protein ligase E3A

2

0

High-throughput

0.328

High

622686

VPS36
Vacuolar protein-sorting-associated protein 36

2

0

High-throughput

0.328

High

622687

TAXB1
Tax1-binding protein 1

2

0

High-throughput

0.328

High

622691

MINY1
Ubiquitin carboxyl-terminal hydrolase MINDY-1

2

0

High-throughput

0.328

High

622704

UBL7
Ubiquitin-like protein 7

2

0

High-throughput

0.328

High

622718

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

2

0

High-throughput

0.328

High

280527

KRT34
Keratin, type I cuticular Ha4

2

0

High-throughput

0.316

High

498212

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

2

0

High-throughput

0.298

High

622650

PEBP1
Phosphatidylethanolamine-binding protein 1

2

0

High-throughput

0.298

High

622660

DNLI4
DNA ligase 4

1

0

High-throughput

0.288

High

622665

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

0

High-throughput

0.279

Low

622675

KCNC3
Potassium voltage-gated channel subfamily C member 3

1

0

High-throughput

0.279

Low

622689

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.279

Low

622690

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.279

Low

622692

TTC9C
Tetratricopeptide repeat protein 9C

1

0

High-throughput

0.279

Low

622694

S43A3
Equilibrative nucleobase transporter 1

1

0

High-throughput

0.279

Low

622700

UFD1
Ubiquitin recognition factor in ER-associated degradation protein 1

1

0

High-throughput

0.279

Low

622702

T106A
Transmembrane protein 106A

1

0

High-throughput

0.279

Low

622684

5MP2
eIF5-mimic protein 2

1

0

High-throughput

0.269

Low

622715

TCAL9
Transcription elongation factor A protein-like 9

1

0

High-throughput

0.269

Low

119176

LEG9
Galectin-9

1

0

High-throughput

0.249

Low

486461

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.249

Low

622653

COIL
Coilin

1

0

High-throughput

0.249

Low

622658

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

0

High-throughput

0.249

Low

622664

ATX3
Ataxin-3

1

0

High-throughput

0.249

Low

622667

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

622673

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.249

Low

622682

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.249

Low

622683

UBP53
Inactive ubiquitin carboxyl-terminal hydrolase 53

1

0

Small-scale

0.249

Low

622708

BRF2
Transcription factor IIIB 50 kDa subunit

1

0

High-throughput

0.249

Low

622709

NMRL1
NmrA-like family domain-containing protein 1

1

0

High-throughput

0.249

Low

496324

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024