Protein: ITIH4
Inter-alpha-trypsin inhibitor heavy chain H4 (ITI heavy chain H4) (ITI-HC4) (Inter-alpha-inhibitor heavy chain 4) (Inter-alpha-trypsin inhibitor family heavy chain-related protein) (IHRP) (Plasma kallikrein sensitive glycoprotein 120) (Gp120) (PK-120) [Cleaved into: 70 kDa inter-alpha-trypsin inhibitor heavy chain H4; 35 kDa inter-alpha-trypsin inhibitor heavy chain H4]

Gene: ITIH4
Organism: Homo sapiens
Interactions: 31
UniProt ID: Q14624

Gene Ontology (top 5):
GO:0004866 - endopeptidase inhibitor activity
GO:0004867 - serine-type endopeptidase inhibitor activity
GO:0005576 - extracellular region
GO:0005886 - plasma membrane
GO:0006953 - acute-phase response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

126383

MATN2
Matrilin-2

1

4

High-throughput

0.691

High

198440

KLK10
Kallikrein-10

1

4

High-throughput

0.691

High

177891

TMPS2
Transmembrane protease serine 2

1

1

High-throughput

0.665

High

420744

KLK1
Kallikrein-1

1

5

Small-scale

0.647

High

344670

CO3
Complement C3

1

0

High-throughput

0.586

High

640003

PTX3
Pentraxin-related protein PTX3

1

1

Small-scale

0.536

High

183027

P2RX6
P2X purinoceptor 6

1

1

High-throughput

0.536

High

686659

CCR1
C-C chemokine receptor type 1

1

3

High-throughput

0.536

High

1056186

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

2

High-throughput

0.536

High

924579

GRB2
Growth factor receptor-bound protein 2

1

1

High-throughput

0.508

High

1056179

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

2

High-throughput

0.489

High

1056181

RHBL4
Rhomboid-related protein 4

1

2

High-throughput

0.489

High

1056182

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

2

High-throughput

0.489

High

1056185

PHF11
PHD finger protein 11

1

2

High-throughput

0.489

High

119376

LEG9
Galectin-9

1

2

Small-scale

0.479

High

209990

PRC1
Protein regulator of cytokinesis 1

1

1

High-throughput

0.479

High

322627

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.479

High

363149

FINC
Fibronectin

1

6

Small-scale

0.479

High

397690

IC1
Plasma protease C1 inhibitor

1

2

High-throughput

0.479

High

572359

LEG3
Galectin-3

1

2

Small-scale

0.479

High

497021

TAU
Microtubule-associated protein tau

1

4

Small-scale

0.445

High

121155

LEG8
Galectin-8

1

2

Small-scale

0.437

High

308709

KI20A
Kinesin-like protein KIF20A

1

2

High-throughput

0.437

High

818044

SOX2
Transcription factor SOX-2

1

3

High-throughput

0.437

High

1056178

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.437

High

1056180

BRWD3
Bromodomain and WD repeat-containing protein 3

1

2

High-throughput

0.437

High

1056184

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.437

High

1056183

P63
Tumor protein 63

1

0

High-throughput

0.251

Low

148815

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

824005

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

961113

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024