Protein: LRC8A
Volume-regulated anion channel subunit LRRC8A (Leucine-rich repeat-containing protein 8A) (HsLRRC8A) (Swelling protein 1)

Gene: LRC8A, LRRC8A
Organism: Homo sapiens
Interactions: 83
UniProt ID: Q8IWT6

Gene Ontology (top 5):
GO:0001678 - intracellular glucose homeostasis
GO:0002329 - pre-B cell differentiation
GO:0005225 - volume-sensitive anion channel activity
GO:0005737 - cytoplasm
GO:0005765 - lysosomal membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1160579

LRC8B
Volume-regulated anion channel subunit LRRC8B

3

17

Small-scale

0.861

High

1219403

LRC8A
Volume-regulated anion channel subunit LRRC8A

3

17

Small-scale

0.796

High

540313

GPIX
Platelet glycoprotein IX

1

9

High-throughput

0.691

High

121187

LEG8
Galectin-8

3

5

High-throughput

0.667

High

1219407

5HT3C
5-hydroxytryptamine receptor 3C

3

7

High-throughput

0.667

High

1155896

LRC8E
Volume-regulated anion channel subunit LRRC8E

1

19

Small-scale

0.665

High

658258

5HT2C
5-hydroxytryptamine receptor 2C

2

4

High-throughput

0.628

High

1166901

DLK2
Protein delta homolog 2

2

4

High-throughput

0.628

High

385131

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.618

High

1183838

LRC8D
Volume-regulated anion channel subunit LRRC8D

1

18

Small-scale

0.618

High

1198089

TM11B
Transmembrane protease serine 11B

1

2

High-throughput

0.618

High

1219406

LRC8C
Volume-regulated anion channel subunit LRRC8C

1

16

Small-scale

0.618

High

1160136

S39A4
Zinc transporter ZIP4

2

1

High-throughput

0.611

High

409788

GLPB
Glycophorin-B

2

0

High-throughput

0.602

High

445226

STS
Steryl-sulfatase

2

0

High-throughput

0.602

High

1219425

FADS3
Fatty acid desaturase 3

2

0

High-throughput

0.602

High

1219408

CLC4D
C-type lectin domain family 4 member D

1

0

High-throughput

0.586

High

126027

UPK1A
Uroplakin-1a

1

4

High-throughput

0.536

High

234029

O10H2
Olfactory receptor 10H2

1

5

High-throughput

0.536

High

326121

TSN15
Tetraspanin-15

1

3

High-throughput

0.536

High

506332

ACHB
Acetylcholine receptor subunit beta

1

3

High-throughput

0.536

High

654517

CALX
Calnexin

1

3

High-throughput

0.536

High

798521

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

1

2

High-throughput

0.536

High

802352

5HT3A
5-hydroxytryptamine receptor 3A

1

8

High-throughput

0.536

High

816604

CXA8
Gap junction alpha-8 protein

1

6

High-throughput

0.536

High

878537

PSA
Puromycin-sensitive aminopeptidase

1

4

High-throughput

0.536

High

1083457

C3AR
C3a anaphylatoxin chemotactic receptor

1

7

High-throughput

0.536

High

1109746

CC50B
Cell cycle control protein 50B

1

1

High-throughput

0.536

High

1117551

NKAI1
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1

1

2

High-throughput

0.536

High

1219404

SIDT2
SID1 transmembrane family member 2

1

3

High-throughput

0.536

High

1219414

TTYH1
Protein tweety homolog 1

1

5

High-throughput

0.536

High

1219422

C5AR2
C5a anaphylatoxin chemotactic receptor 2

1

8

High-throughput

0.536

High

1219423

HCST
Hematopoietic cell signal transducer

1

3

High-throughput

0.536

High

217337

TYOBP
TYRO protein tyrosine kinase-binding protein

1

0

High-throughput

0.513

High

430705

CD3E
T-cell surface glycoprotein CD3 epsilon chain

1

0

High-throughput

0.513

High

1174889

SMIM5
Small integral membrane protein 5

1

0

High-throughput

0.513

High

1189983

KCNKI
Potassium channel subfamily K member 18

1

0

High-throughput

0.513

High

1217360

CNGA4
Cyclic nucleotide-gated channel alpha-4

1

0

High-throughput

0.513

High

1219410

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

1

0

High-throughput

0.513

High

1219413

CREL1
Protein disulfide isomerase CRELD1

1

0

High-throughput

0.513

High

161109

CLGN
Calmegin

1

3

High-throughput

0.489

High

1107975

LEG9B
Galectin-9B

1

5

High-throughput

0.489

High

1219412

ZDH12
Palmitoyltransferase ZDHHC12

1

1

High-throughput

0.489

High

1219420

DISC1
Disrupted in schizophrenia 1 protein

1

1

High-throughput

0.489

High

331312

CHK2
Serine/threonine-protein kinase Chk2

1

3

Small-scale

0.484

High

119441

LEG9
Galectin-9

1

5

High-throughput

0.479

High

120526

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

163874

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

5

High-throughput

0.479

High

205638

TGON2
Trans-Golgi network integral membrane protein 2

1

4

High-throughput

0.479

High

350324

RASK
GTPase KRas

1

17

High-throughput

0.479

High

374506

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

20

High-throughput

0.479

High

432037

HS90A
Heat shock protein HSP 90-alpha

1

4

High-throughput

0.479

High

436394

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.479

High

438335

HS90B
Heat shock protein HSP 90-beta

1

4

High-throughput

0.479

High

507112

LAMP1
Lysosome-associated membrane glycoprotein 1

1

2

High-throughput

0.479

High

538308

ENPL
Endoplasmin

1

4

High-throughput

0.479

High

545486

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.479

High

564604

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.479

High

686810

GP183
G-protein coupled receptor 183

1

5

High-throughput

0.479

High

892474

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

894196

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

900667

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

915813

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.479

High

925419

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

951139

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

1076654

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.479

High

1114497

ZACN
Ligand-gated cation channel ZACN

1

9

High-throughput

0.479

High

1170711

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.479

High

1219405

RN149
E3 ubiquitin-protein ligase RNF149

1

4

High-throughput

0.479

High

1219409

LPAR1
Lysophosphatidic acid receptor 1

1

4

High-throughput

0.479

High

1219415

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

1219417

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

1219418

POPD2
Popeye domain-containing protein 2

1

1

High-throughput

0.479

High

1219421

OTULL
Inactive ubiquitin thioesterase OTULINL

1

3

High-throughput

0.479

High

1219424

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

415403

ATPB
ATP synthase subunit beta, mitochondrial

1

0

High-throughput

0.458

High

1087562

CAH9
Carbonic anhydrase 9

1

0

High-throughput

0.458

High

1219419

ANLN
Anillin

1

3

High-throughput

0.437

High

887180

D131A
Beta-defensin 131A

1

0

High-throughput

0.279

Low

1134682

DIK1A
Divergent protein kinase domain 1A

1

0

High-throughput

0.279

Low

1219411

BSCL2
Seipin

1

0

High-throughput

0.279

Low

1219416

IPPK
Inositol-pentakisphosphate 2-kinase

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024