Protein: CO2
Complement C2 (EC 3.4.21.43) (C3/C5 convertase) [Cleaved into: Complement C2b fragment; Complement C2a fragment]

Gene: CO2, C2
Organism: Homo sapiens
Interactions: 15
UniProt ID: P06681

Gene Ontology (top 5):
GO:0004252 - serine-type endopeptidase activity
GO:0005576 - extracellular region
GO:0005601 - classical-complement-pathway C3/C5 convertase complex
GO:0005615 - extracellular space
GO:0006508 - proteolysis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

416127

DAF
Complement decay-accelerating factor

2

11

High-throughput

0.789

High

416128

C1S
Complement C1s subcomponent

2

16

Small-scale

0.778

High

416129

CO4A
Complement C4-A

2

20

Small-scale

0.778

High

119682

MASP2
Mannan-binding lectin serine protease 2

1

16

Small-scale

0.647

High

416133

MASP1
Mannan-binding lectin serine protease 1

1

16

Small-scale

0.647

High

416130

CO4B
Complement C4-B

1

20

Small-scale

0.618

High

416131

MUC1
Mucin-1

2

2

High-throughput

0.606

High

416132

STOM
Stomatin

2

1

High-throughput

0.606

High

416136

F209A
Protein FAM209A

2

1

High-throughput

0.606

High

416137

SC11C
Signal peptidase complex catalytic subunit SEC11C

2

0

High-throughput

0.580

High

216650

CREB3
Cyclic AMP-responsive element-binding protein 3

1

2

High-throughput

0.523

High

416134

NTCP
Hepatic sodium/bile acid cotransporter

2

0

High-throughput

0.316

High

416135

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

0

High-throughput

0.316

High

416138

S35C2
Solute carrier family 35 member C2

2

0

High-throughput

0.316

High

416139

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

0

High-throughput

0.316

High


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Last updated: 15 Jul 2024