Protein: PTN
Pleiotrophin (PTN) (Heparin-binding brain mitogen) (HBBM) (Heparin-binding growth factor 8) (HBGF-8) (Heparin-binding growth-associated molecule) (HB-GAM) (Heparin-binding neurite outgrowth-promoting factor) (HBNF) (Heparin-binding neurite outgrowth-promoting factor 1) (HBNF-1) (Osteoblast-specific factor 1) (OSF-1)

Gene: PTN
Organism: Homo sapiens
Interactions: 116
UniProt ID: P21246

Gene Ontology (top 5):
GO:0002232 - leukocyte chemotaxis involved in inflammatory response
GO:0002690 - positive regulation of leukocyte chemotaxis
GO:0004864 - protein phosphatase inhibitor activity
GO:0005178 - integrin binding
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

597358

PTN
Pleiotrophin

1

1

High-throughput

0.656

High

597430

UBQL4
Ubiquilin-4

2

6

High-throughput

0.620

High

597437

ALK
ALK tyrosine kinase receptor

2

1

Small-scale

0.595

High

597434

DJB11
DnaJ homolog subfamily B member 11

2

0

High-throughput

0.594

High

597384

ASPH
Aspartyl/asparaginyl beta-hydroxylase

2

0

High-throughput

0.580

High

597385

CHD3
Chromodomain-helicase-DNA-binding protein 3

2

1

High-throughput

0.566

High

506099

ITAM
Integrin alpha-M

1

1

Small-scale

0.554

High

597427

NEK6
Serine/threonine-protein kinase Nek6

1

1

Small-scale

0.549

High

597387

PTPRS
Receptor-type tyrosine-protein phosphatase S

1

3

High-throughput

0.541

High

597413

CK5P2
CDK5 regulatory subunit-associated protein 2

1

1

High-throughput

0.541

High

121679

PSD11
26S proteasome non-ATPase regulatory subunit 11

1

0

High-throughput

0.518

High

124972

CACB4
Voltage-dependent L-type calcium channel subunit beta-4

1

0

High-throughput

0.518

High

165160

PLXB2
Plexin-B2

1

0

High-throughput

0.518

High

234322

GSDME
Gasdermin-E

1

0

High-throughput

0.518

High

282403

STC2
Stanniocalcin-2

1

0

High-throughput

0.518

High

351646

GLHA
Glycoprotein hormones alpha chain

1

0

High-throughput

0.518

High

364827

FRIL
Ferritin light chain

1

0

High-throughput

0.518

High

423140

PDIA1
Protein disulfide-isomerase

1

0

High-throughput

0.518

High

448288

GSTP1
Glutathione S-transferase P

1

0

High-throughput

0.518

High

597365

T2FA
General transcription factor IIF subunit 1

1

0

High-throughput

0.518

High

597373

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.518

High

597376

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.518

High

597380

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

0

High-throughput

0.518

High

597381

BL1S1
Biogenesis of lysosome-related organelles complex 1 subunit 1

1

0

High-throughput

0.518

High

597386

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

0

High-throughput

0.518

High

597389

WFDC2
WAP four-disulfide core domain protein 2

1

0

High-throughput

0.518

High

597394

LAMA4
Laminin subunit alpha-4

1

0

High-throughput

0.518

High

597405

RIT1
GTP-binding protein Rit1

1

0

High-throughput

0.518

High

597406

FAKD4
FAST kinase domain-containing protein 4

1

0

High-throughput

0.518

High

597424

EVA1A
Protein eva-1 homolog A

1

0

High-throughput

0.518

High

597432

ITSN2
Intersectin-2

1

0

High-throughput

0.518

High

597436

TKNK
Tachykinin-3

1

0

High-throughput

0.518

High

597444

CAD10
Cadherin-10

1

0

High-throughput

0.518

High

597371

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

1

Small-scale

0.515

High

597382

ROR1
Inactive tyrosine-protein kinase transmembrane receptor ROR1

1

2

Small-scale

0.501

High

597422

RN167
E3 ubiquitin-protein ligase RNF167

1

1

Small-scale

0.501

High

597369

PSB10
Proteasome subunit beta type-10

1

1

High-throughput

0.494

High

597372

AF9
Protein AF-9

1

1

High-throughput

0.494

High

597374

ATRX
Transcriptional regulator ATRX

1

1

High-throughput

0.494

High

597388

ASPP2
Apoptosis-stimulating of p53 protein 2

1

1

High-throughput

0.494

High

597411

CREL1
Protein disulfide isomerase CRELD1

1

2

High-throughput

0.494

High

568536

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

0

High-throughput

0.493

High

597368

TGFR2
TGF-beta receptor type-2

1

0

High-throughput

0.493

High

597378

SERPH
Serpin H1

1

0

High-throughput

0.493

High

597404

KLK6
Kallikrein-6

1

0

High-throughput

0.493

High

214848

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.486

High

597377

GSK3B
Glycogen synthase kinase-3 beta

1

0

High-throughput

0.486

High

597383

B2CL1
Bcl-2-like protein 1

1

0

High-throughput

0.486

High

597390

IMB1
Importin subunit beta-1

1

0

High-throughput

0.486

High

597415

FEZ1
Fasciculation and elongation protein zeta-1

1

0

High-throughput

0.486

High

597425

RM44
Large ribosomal subunit protein mL44

1

0

High-throughput

0.486

High

597375

BAG6
Large proline-rich protein BAG6

1

6

High-throughput

0.481

High

597438

UBQL1
Ubiquilin-1

1

6

High-throughput

0.481

High

396565

ITB3
Integrin beta-3

1

1

Small-scale

0.479

High

419155

ITAV
Integrin alpha-V

1

1

Small-scale

0.479

High

597361

PTPRZ
Receptor-type tyrosine-protein phosphatase zeta

1

4

Small-scale

0.479

High

597370

STAT3
Signal transducer and activator of transcription 3

1

1

Small-scale

0.479

High

309833

GA45G
Growth arrest and DNA damage-inducible protein GADD45 gamma

1

1

High-throughput

0.464

High

597362

GA45A
Growth arrest and DNA damage-inducible protein GADD45 alpha

1

1

High-throughput

0.464

High

597393

T22D1
TSC22 domain family protein 1

1

0

High-throughput

0.460

High

597363

CTNB1
Catenin beta-1

1

0

Small-scale

0.458

High

597400

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

496289

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.445

High

597401

RBM23
Probable RNA-binding protein 23

1

1

High-throughput

0.439

High

597418

HGH1
Protein HGH1 homolog

1

1

High-throughput

0.439

High

345054

CYTA
Cystatin-A

1

0

High-throughput

0.438

High

597397

Q6IA98
RNPC4 protein

1

1

High-throughput

0.417

High

597407

Q96BK8
Protein HGH1 homolog

1

1

High-throughput

0.417

High

597421

TAF1D
TATA box-binding protein-associated factor RNA polymerase I subunit D

2

0

High-throughput

0.323

High

213477

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

2

0

High-throughput

0.319

High

124760

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

0

High-throughput

0.282

High

147217

TXND9
Thioredoxin domain-containing protein 9

1

0

High-throughput

0.282

High

195592

SGSM2
Small G protein signaling modulator 2

1

0

High-throughput

0.282

High

297898

ST65G
STAGA complex 65 subunit gamma

1

0

High-throughput

0.282

High

312477

ARI2
E3 ubiquitin-protein ligase ARIH2

1

0

High-throughput

0.282

High

400230

RLA1
Large ribosomal subunit protein P1

1

0

High-throughput

0.282

High

454004

COX6C
Cytochrome c oxidase subunit 6C

1

0

High-throughput

0.282

High

597359

SAT1
Diamine acetyltransferase 1

1

0

High-throughput

0.282

High

597360

GPDA
Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic

1

0

High-throughput

0.282

High

597367

ATPG
ATP synthase subunit gamma, mitochondrial

1

0

High-throughput

0.282

High

597379

RACK1
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.282

High

597391

MD2BP
MAD2L1-binding protein

1

0

High-throughput

0.282

High

597392

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

0

High-throughput

0.282

High

597398

GLYAT
Glycine N-acyltransferase

1

0

High-throughput

0.282

High

597399

PMF1
Polyamine-modulated factor 1

1

0

High-throughput

0.282

High

597403

GIPC2
PDZ domain-containing protein GIPC2

1

0

High-throughput

0.282

High

597408

S2536
Solute carrier family 25 member 36

1

0

High-throughput

0.282

High

597410

HBAP1
HSPB1-associated protein 1

1

0

High-throughput

0.282

High

597412

NP1L5
Nucleosome assembly protein 1-like 5

1

0

High-throughput

0.282

High

597414

MYCBP
c-Myc-binding protein

1

0

High-throughput

0.282

High

597419

BTBD2
BTB/POZ domain-containing protein 2

1

0

High-throughput

0.282

High

597423

CAAP1
Caspase activity and apoptosis inhibitor 1

1

0

High-throughput

0.282

High

597426

ABC3G
DNA dC->dU-editing enzyme APOBEC-3G

1

0

High-throughput

0.282

High

597428

MKKS
Molecular chaperone MKKS

1

0

High-throughput

0.282

High

597429

SAS10
Something about silencing protein 10

1

0

High-throughput

0.282

High

597431

ARL15
ADP-ribosylation factor-like protein 15

1

0

High-throughput

0.282

High

597433

BCCIP
BRCA2 and CDKN1A-interacting protein

1

0

High-throughput

0.282

High

597435

CRCT1
Cysteine-rich C-terminal protein 1

1

0

High-throughput

0.282

High

597439

DUS12
Dual specificity protein phosphatase 12

1

0

High-throughput

0.282

High

597440

LC7L2
Putative RNA-binding protein Luc7-like 2

1

0

High-throughput

0.282

High

597441

WASC3
WASH complex subunit 3

1

0

High-throughput

0.282

High

597443

SNCAP
Synphilin-1

1

0

High-throughput

0.282

High

597395

C19L2
CWF19-like protein 2

1

0

High-throughput

0.269

Low

119809

SMAP
Small acidic protein

1

0

High-throughput

0.265

Low

245941

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.265

Low

597402

PIAS4
E3 SUMO-protein ligase PIAS4

1

0

High-throughput

0.265

Low

597409

GASP2
G-protein coupled receptor-associated sorting protein 2

1

0

High-throughput

0.265

Low

597416

BARD1
BRCA1-associated RING domain protein 1

1

0

High-throughput

0.265

Low

597417

CG025
UPF0415 protein C7orf25

1

0

High-throughput

0.265

Low

597420

MFRP
Membrane frizzled-related protein

1

0

Small-scale

0.261

Low

398438

CP2E1
Cytochrome P450 2E1

1

0

High-throughput

0.251

Low

597364

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.251

Low

597366

MSX2
Homeobox protein MSX-2

1

0

High-throughput

0.249

Low

597396

Q5T8Z1
COMMD3-BMI1 readthrough

1

0

High-throughput

0.238

Low

597442

SPIN1
Spindlin-1

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024