Protein: GCYA1
Guanylate cyclase soluble subunit alpha-1 (GCS-alpha-1) (EC 4.6.1.2) (Guanylate cyclase soluble subunit alpha-3) (GCS-alpha-3) (Soluble guanylate cyclase large subunit)

Gene: GCYA1, GUCY1A1
Organism: Homo sapiens
Interactions: 39
UniProt ID: Q02108

Gene Ontology (top 5):
GO:0004383 - guanylate cyclase activity
GO:0005525 - GTP binding
GO:0005829 - cytosol
GO:0006182 - cGMP biosynthetic process
GO:0007263 - nitric oxide mediated signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

969011

GCYB1
Guanylate cyclase soluble subunit beta-1

4

8

Small-scale

0.898

High

234207

PEPL
Periplakin

1

1

High-throughput

0.536

High

533215

PLSL
Plastin-2

1

1

High-throughput

0.536

High

667948

SPB3
Serpin B3

1

3

High-throughput

0.536

High

678437

S10A7
Protein S100-A7

1

1

High-throughput

0.536

High

820298

SPB4
Serpin B4

1

3

High-throughput

0.536

High

969017

S1A7A
Protein S100-A7A

1

1

High-throughput

0.536

High

969025

AGAP1
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1

1

0

Small-scale

0.529

High

800750

MK08
Mitogen-activated protein kinase 8

1

0

High-throughput

0.518

High

969026

NEMO
NF-kappa-B essential modulator

1

0

High-throughput

0.518

High

120078

ST2B1
Sulfotransferase 2B1

1

0

High-throughput

0.513

High

428573

INVO
Involucrin

1

0

High-throughput

0.513

High

452219

HMOX1
Heme oxygenase 1

1

0

High-throughput

0.513

High

588417

TYPH
Thymidine phosphorylase

1

0

High-throughput

0.513

High

666448

RABP2
Cellular retinoic acid-binding protein 2

1

0

High-throughput

0.513

High

787719

HUTH
Histidine ammonia-lyase

1

0

High-throughput

0.513

High

814369

AL1A3
Retinaldehyde dehydrogenase 3

1

0

High-throughput

0.513

High

935765

HBB
Hemoglobin subunit beta

1

0

High-throughput

0.513

High

969018

PA24D
Cytosolic phospholipase A2 delta

1

0

High-throughput

0.513

High

199719

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

1

0

High-throughput

0.493

High

271863

SPB7
Serpin B7

1

3

High-throughput

0.489

High

738746

SPB5
Serpin B5

1

3

High-throughput

0.489

High

814933

LEG7
Galectin-7

1

5

High-throughput

0.489

High

885232

EPIPL
Epiplakin

1

1

High-throughput

0.489

High

969019

ANKY2
Ankyrin repeat and MYND domain-containing protein 2

1

5

High-throughput

0.489

High

969024

CHIP
E3 ubiquitin-protein ligase CHIP

1

4

Small-scale

0.479

High

386557

P53
Cellular tumor antigen p53

1

0

Small-scale

0.458

High

934107

CSK21
Casein kinase II subunit alpha

1

0

Small-scale

0.458

High

969012

IRF8
Interferon regulatory factor 8

1

0

Small-scale

0.458

High

969021

CSN5
COP9 signalosome complex subunit 5

1

0

Small-scale

0.458

High

969022

CSN4
COP9 signalosome complex subunit 4

1

0

Small-scale

0.458

High

361991

FIBG
Fibrinogen gamma chain

1

0

High-throughput

0.279

Low

872907

ARSF
Arylsulfatase F

1

0

High-throughput

0.279

Low

969013

TGM3
Protein-glutamine gamma-glutamyltransferase E

1

0

High-throughput

0.279

Low

969014

TRI29
Tripartite motif-containing protein 29

1

0

High-throughput

0.279

Low

969016

SBSN
Suprabasin

1

0

High-throughput

0.279

Low

969020

TMM40
Transmembrane protein 40

1

0

High-throughput

0.279

Low

969023

CALL5
Calmodulin-like protein 5

1

0

High-throughput

0.279

Low

969015

H37
Histone H3-7

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024