Protein: TLR5
Toll-like receptor 5 (Toll/interleukin-1 receptor-like protein 3)

Gene: TLR5
Organism: Homo sapiens
Interactions: 31
UniProt ID: O60602

Gene Ontology (top 5):
GO:0002224 - toll-like receptor signaling pathway
GO:0004888 - transmembrane signaling receptor activity
GO:0005149 - interleukin-1 receptor binding
GO:0005886 - plasma membrane
GO:0006954 - inflammatory response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

237439

IRAK4
Interleukin-1 receptor-associated kinase 4

2

20

Small-scale

0.754

High

237435

MYD88
Myeloid differentiation primary response protein MyD88

5

19

Small-scale

0.701

High

237437

CNPY3
Protein canopy homolog 3

2

11

High-throughput

0.628

High

120116

TLR4
Toll-like receptor 4

1

19

Small-scale

0.618

High

177591

SIGL5
Sialic acid-binding Ig-like lectin 5

1

20

Small-scale

0.618

High

211412

SIGL6
Sialic acid-binding Ig-like lectin 6

1

20

Small-scale

0.618

High

237424

CD33
Myeloid cell surface antigen CD33

1

20

Small-scale

0.618

High

237425

CD22
B-cell receptor CD22

1

20

Small-scale

0.618

High

237426

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

3

Small-scale

0.618

High

237434

SIG11
Sialic acid-binding Ig-like lectin 11

1

20

Small-scale

0.618

High

237440

SIGL7
Sialic acid-binding Ig-like lectin 7

1

20

Small-scale

0.618

High

237442

SIGL9
Sialic acid-binding Ig-like lectin 9

1

20

Small-scale

0.618

High

237420

TLR5
Toll-like receptor 5

1

17

Small-scale

0.590

High

237421

DHRS3
Short-chain dehydrogenase/reductase 3

2

3

High-throughput

0.574

High

237443

DHRS7
Dehydrogenase/reductase SDR family member 7

2

2

High-throughput

0.574

High

237445

SNX14
Sorting nexin-14

2

1

High-throughput

0.574

High

237423

P53
Cellular tumor antigen p53

2

5

Small-scale

0.533

High

237427

IRAK1
Interleukin-1 receptor-associated kinase 1

1

20

Small-scale

0.479

High

237428

KPCD1
Serine/threonine-protein kinase D1

1

2

Small-scale

0.479

High

237430

TCAM1
TIR domain-containing adapter molecule 1

1

8

Small-scale

0.479

High

237432

PAUF
Pancreatic adenocarcinoma up-regulated factor

1

2

Small-scale

0.479

High

237438

RN216
E3 ubiquitin-protein ligase RNF216

1

4

Small-scale

0.439

High

234602

MA1A2
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB

2

0

High-throughput

0.328

High

237422

CNEP1
CTD nuclear envelope phosphatase 1

2

0

High-throughput

0.328

High

237436

PXL2A
Peroxiredoxin-like 2A

2

0

High-throughput

0.328

High

237441

TMX2
Thioredoxin-related transmembrane protein 2

2

0

High-throughput

0.328

High

237444

PTH2
Peptidyl-tRNA hydrolase 2, mitochondrial

2

0

High-throughput

0.328

High

237429

CHSS3
Chondroitin sulfate synthase 3

1

0

High-throughput

0.279

Low

237431

ACO12
Acetyl-coenzyme A thioesterase

1

0

High-throughput

0.279

Low

237433

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024